LOCUS       NM_001107398            4525 bp    mRNA    linear   ROD 07-MAY-2024
DEFINITION  Rattus norvegicus WD repeat domain 33 (Wdr33), mRNA.
ACCESSION   NM_001107398 XM_001058355 XM_226076
VERSION     NM_001107398.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4525)
  AUTHORS   Gruber,A.R., Martin,G., Keller,W. and Zavolan,M.
  TITLE     Means to an end: mechanisms of alternative polyadenylation of
            messenger RNA precursors
  JOURNAL   Wiley Interdiscip Rev RNA 5 (2), 183-196 (2014)
   PUBMED   24243805
  REMARK    Review article
REFERENCE   2  (bases 1 to 4525)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 4525)
  AUTHORS   Chan,S., Choi,E.A. and Shi,Y.
  TITLE     Pre-mRNA 3'-end processing complex assembly and function
  JOURNAL   Wiley Interdiscip Rev RNA 2 (3), 321-335 (2011)
   PUBMED   21957020
  REMARK    Review article
REFERENCE   4  (bases 1 to 4525)
  AUTHORS   Ito,S., Sakai,A., Nomura,T., Miki,Y., Ouchida,M., Sasaki,J. and
            Shimizu,K.
  TITLE     A novel WD40 repeat protein, WDC146, highly expressed during
            spermatogenesis in a stage-specific manner
  JOURNAL   Biochem Biophys Res Commun 280 (3), 656-663 (2001)
   PUBMED   11162572
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On Aug 13, 2010 this sequence version replaced NM_001107398.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.2660719.1,
                                           SRR26360194.441499.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-135               JAXUCZ010000018.1  23706715-23706849
            136-362             JAXUCZ010000018.1  23733543-23733769
            363-431             JAXUCZ010000018.1  23735718-23735786
            432-536             JAXUCZ010000018.1  23736446-23736550
            537-632             JAXUCZ010000018.1  23740374-23740469
            633-784             JAXUCZ010000018.1  23740646-23740797
            785-882             JAXUCZ010000018.1  23742451-23742548
            883-1009            JAXUCZ010000018.1  23781912-23782038
            1010-1164           JAXUCZ010000018.1  23783885-23784039
            1165-1243           JAXUCZ010000018.1  23784138-23784216
            1244-1354           JAXUCZ010000018.1  23785285-23785395
            1355-1449           JAXUCZ010000018.1  23789284-23789378
            1450-1536           JAXUCZ010000018.1  23790033-23790119
            1537-1676           JAXUCZ010000018.1  23790363-23790502
            1677-1829           JAXUCZ010000018.1  23791340-23791492
            1830-2900           JAXUCZ010000018.1  23791736-23792806
            2901-3009           JAXUCZ010000018.1  23796701-23796809
            3010-3448           JAXUCZ010000018.1  23800190-23800628
            3449-3612           JAXUCZ010000018.1  23805604-23805767
            3613-3708           JAXUCZ010000018.1  23805862-23805957
            3709-3924           JAXUCZ010000018.1  23807323-23807538
            3925-4525           JAXUCZ010000018.1  23809085-23809685
FEATURES             Location/Qualifiers
     source          1..4525
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p12"
     gene            1..4525
                     /gene="Wdr33"
                     /note="WD repeat domain 33"
                     /db_xref="GeneID:307524"
                     /db_xref="RGD:1309230"
     exon            1..135
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            136..362
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     CDS             159..4154
                     /gene="Wdr33"
                     /note="WD repeat-containing protein 33"
                     /codon_start=1
                     /product="pre-mRNA 3' end processing protein WDR33"
                     /protein_id="NP_001100868.2"
                     /db_xref="GeneID:307524"
                     /db_xref="RGD:1309230"
                     /translation="MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFD
                     GKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNP
                     MNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAH
                     DSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFA
                     TCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPK
                     TGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEA
                     TAVAWHPVHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILCS
                     GSNDHTSKFWTRNRPGDKMRDRYNLNLLPGMSEDGVEYDDLEPNSLAVIPGMGIPEQL
                     KLAMEQEQMGKDESNDIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQAW
                     MQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQ
                     KQADQIQPPPSSGTPLLGPQPFSGQGPMSQIPQGFQQPHPSQQMPLVAQMGPPGPQGQ
                     FRAPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGP
                     HGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPAPQGHMGPQGPPGTQGMQ
                     GPPGPRGMQGPPHPHGIQGGPTSQGIQGPLMGLNPRGMQGPPGPRENQGPAPQGIMIG
                     HPPQEMRGPHPPSGLLGHGPQEMRGPQEMRGMQGPPPQGSMLGPPQELRGPSGSQGQQ
                     GPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKAPLLGDGPRAPFNQ
                     EGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHLGPMSERRHEQS
                     GGPEHGPDRGPFRGGQDCRGPPDRRGSHPDFPDDFSRPDDFHPDKRFGHRLREFEGRG
                     GPLPQEEKWRRGGPGPPFPPDHREFNEGDGRGAARGPPGAWEGRRPGDERFPRDPDDP
                     RFRGRREESFRRGAPPRHEGRAPPRGRDNFPGPDDFGPEEVFDASDEAARGRDLRGRG
                     RGTPRGGSRKCLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDAPRPDHPPHDGH
                     SPASRERSSSLQGMDMASLPPRKRPWHDGSGTSEHREMEAQGGPSEDRGSKGRGGPGP
                     SQRVPKSGRSSSLDGDHHDGYHRDEPFGGPPGSSSSSRGGRSGSNWGRGSNMNSGPPR
                     RGTSRGSGRGR"
     exon            363..431
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            432..536
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            537..632
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            633..784
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            785..882
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            883..1009
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1164
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1243
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1354
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            1355..1449
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1536
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            1537..1676
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            1677..1829
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            1830..2900
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            2901..3009
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            3010..3448
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            3449..3612
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            3613..3708
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            3709..3924
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
     exon            3925..4525
                     /gene="Wdr33"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagatggcg gctgcatctt tgaaggagag gaattgagag tggggagaag ggaagaggac
       61 cagacgggag agacattccc tacggcgccg aaggacgccg cgctcgcggt taggagctct
      121 tcccggcccc ccacgtgact tagtaggaaa acatcaccat ggctacagaa attggctctc
      181 ctccacgatt tttccatatg ccgaggttcc agcaccaggc tccccgacag ttgttctata
      241 agcggcctga ctttgcacag cagcaggcaa tgcagcagct cacctttgac gggaagcgga
      301 tgagaaaggc cgtgaaccgg aaaaccatag actacaaccc ctctgtcatt aagtatttgg
      361 agaataggat atggcaaaga gatcagagag atatgcgggc aattcagccg gatgcaggtt
      421 attataatga tctggtccca cctataggaa tgttgaataa tcctatgaat gcagtaacaa
      481 cgaaatttgt taggacatca acaaacaaag taaaatgccc agtgtttgtt gtgaggtgga
      541 ccccggaagg aagacggttg gtcactggag cttctagtgg ggagttcacc ttgtggaacg
      601 ggctgacttt caactttgaa accatattgc aggctcatga tagccctgtg agggccatga
      661 cttggtcaca taatgacatg tggatgttga cagcagatca tggaggatat gtgaaatatt
      721 ggcaatccaa catgaacaac gtcaagatgt tccaggcaca taaggaggcg attagagagg
      781 ccagtttctc acccacggat aataaatttg ctacatgctc tgatgacggc actgttagaa
      841 tctgggattt tcttcgttgc catgaggaaa gaattctccg aggtcatggt gctgatgtga
      901 agtgtgtaga ttggcatcca accaaagggt tggttgtttc aggaagtaaa gatagccagc
      961 agccaatcaa gttctgggac cccaagactg ggcagagtct tgcaacactt cacgcccata
     1021 aaaacacggt gatggaagtg aaattaaacc tcaacggcaa ctggctcctc acggcctctc
     1081 gtgaccatct ctgtaagctt ttcgatatcc gaaacctgaa agaagagctt caggtattcc
     1141 gaggtcacaa gaaggaagcc acagctgtag cctggcatcc tgtccacgaa ggactttttg
     1201 ccagcggagg atccgacggc tccttgttat tctggcacgt tggggtggag aaggaagtag
     1261 gtgggatgga gatggcccac gaagggatga tctggagttt ggcttggcat cctctgggac
     1321 atattctctg ctcgggctca aatgaccata ccagcaaatt ctggactcga aatcggccag
     1381 gtgacaaaat gcgagatcga tataatctga accttttacc tggcatgtca gaagacggag
     1441 tagagtatga tgacctggaa cctaatagcc tggcagtgat tccagggatg ggaatcccag
     1501 aacaactgaa actggccatg gagcaggagc agatggggaa agatgaatca aatgacattg
     1561 aaatgacaat tccaggcttg gattggggaa tggaagaagt aatgcaaaag gatcagaaaa
     1621 aagttcctca gaagaaagtc ccttatgcaa agcccattcc tgctcagttc cagcaggcct
     1681 ggatgcaaaa taaagttcca attcctgctc caaatgaggt gctgaatgac aggaaagagg
     1741 atattaagct agaagagaag aaaaaaacac aagcagaaat cgagcaagaa atggccacgc
     1801 tgcagtatac caacccacag cttttagagc aacttaaaat tgaaaggctt gcccagaagc
     1861 aggccgatca gatccagcct cctccctcgt ctggtactcc tctcctcgga cctcagccct
     1921 tttctggtca aggcccaatg tctcagatcc ctcaaggttt tcagcagcct cacccatctc
     1981 agcagatgcc attggtggct caaatggggc ctccaggtcc acagggccag ttcagagccc
     2041 ctggacccca gggacaaatg ggaccacaag gccctccatt gcatcaagga ggtggggggc
     2101 cacaaggatt catgggacca caaggacccc agggccctcc ccagggtctg ccacggcctc
     2161 aggacatgca tggtccacaa ggaatgcaga ggcaccctgg acctcatggc cctttgggac
     2221 ctcaagggcc acccggacct caaggtagtt ctggtcctca aggtcatatg ggtcctcagg
     2281 gtccaccagg acctcagggt cacattggcc cccaaggccc acctgctcct cagggccata
     2341 tgggcccaca gggtcctcct ggtactcaag gaatgcaggg accacctggt cccagaggaa
     2401 tgcaaggacc tcctcatcct catgggatac agggtgggcc aacatctcaa gggatccagg
     2461 gacctctgat gggactgaat ccaagaggaa tgcagggacc cccaggacct cgggagaatc
     2521 agggtcctgc tcctcaaggg ataatgattg gccatccacc tcaggagatg agaggaccac
     2581 atcctccaag tggactgctg ggacatggcc ctcaggaaat gagaggtcct caggagatgc
     2641 ggggcatgca ggggcctcca ccacaggggt caatgttggg ccctccccag gaacttcgag
     2701 gaccctcagg ttcacagggg cagcaggggc caccccaggg ctctttggga cctccacccc
     2761 agggtggcat gcaaggaccc cctggacctc agggacaaca gaacccggca agagggccac
     2821 atccatctca agggccaata ccattccagc agcagaaagc acctctgcta ggtgatgggc
     2881 cccgggcccc cttcaatcag gaaggacaga gtacaggtcc cccacccttg ataccaggcc
     2941 tagggcaaca gggagcacaa ggccgcattc ctcctctgaa ccctggacaa ggacccggcc
     3001 ctaacaaagg tgactctcga ggccctccca accatcacct gggccccatg tcagagaggc
     3061 ggcatgagca gagcggtggt cctgagcatg gtcctgacag gggacctttc cggggtggcc
     3121 aggactgcag gggtcctcct gacaggcgtg gctctcaccc tgatttccct gatgacttca
     3181 gcagaccaga tgacttccat cctgacaagc gctttggcca ccggttacgg gaattcgagg
     3241 gacgaggagg acccttacca caagaagaaa agtggaggcg agggggccct ggacctccct
     3301 ttccacctga tcacagggag ttcaatgagg gggacggccg gggtgcagcc cgaggccctc
     3361 caggggcatg ggaaggccgc agacctggag acgaacgatt cccccgggat cctgatgacc
     3421 cacgatttcg agggcgcaga gaagaaagct ttagaagagg tgctccccca agacacgaag
     3481 gccgtgctcc tccaagagga agggacaact ttcctggtcc tgatgacttt ggtccagaag
     3541 aggttttcga tgcttctgat gaagcagccc gaggacgaga tctcagaggt cgaggccgtg
     3601 gcacccctag agggggatcc aggaagtgct tactccccac tcctgatgag tttcctcgct
     3661 ttgaaggagg acggaagcca gactcctggg atggaaaccg agagcccgga ccaggtcatg
     3721 aacactttcg tgatgctccc cgtcctgatc atccccctca cgatggccat tcaccagcta
     3781 gcagagagcg ctcctcttct ctccaaggca tggacatggc ctccctacca ccccggaagc
     3841 gcccctggca tgatgggtcg ggcacttctg aacacagaga gatggaggcc caaggaggcc
     3901 cctcggagga ccgaggaagc aaaggccgag ggggcccagg accttcccag agagttccaa
     3961 aatccgggcg ttccagctct ttggacggag accatcatga tggataccac agagatgaac
     4021 cttttggtgg ccctccaggc agcagctcat cttctcgagg gggccggagt ggcagtaact
     4081 ggggtagagg gagtaacatg aactctggcc ctccaaggag aggcacttca agaggtagtg
     4141 ggaggggtcg gtaggagggc cgaatcgcct taggcctctc tggatactat ttaagaagtt
     4201 cttgtggact taccacagaa gcaaaaacaa gcctttacca ctgtagccct gaacaattct
     4261 tctggggcag ctgagttcta ttctaggagc ccagtgaggt gctcgagaca aaagactgat
     4321 gccgactccc cagggagttg gccgttttgt cttgtacctc ctcattgctc taagtctccc
     4381 gttcgtttgt gaagagaaaa gctggaatcc tttttttaag tgtcatgaga aatggagcac
     4441 ctccacaaag ttcagttcat gtccaattgg aaatttattt ctatatgtac agtttgtcag
     4501 agaaaaaaac cttgttttgt atgaa
//
