LOCUS       NM_001107705            3417 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus WD repeat domain 3 (Wdr3), mRNA.
ACCESSION   NM_001107705 XM_001065786 XM_227527
VERSION     NM_001107705.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3417)
  AUTHORS   Sloan,K.E., Bohnsack,M.T., Schneider,C. and Watkins,N.J.
  TITLE     The roles of SSU processome components and surveillance factors in
            the initial processing of human ribosomal RNA
  JOURNAL   RNA 20 (4), 540-550 (2014)
   PUBMED   24550520
REFERENCE   2  (bases 1 to 3417)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 3417)
  AUTHORS   Akdi A, Gimenez EM, Garcia-Quispes W, Pastor S, Castell J, Biarnes
            J, Marcos R and Velazquez A.
  TITLE     WDR3 gene haplotype is associated with thyroid cancer risk in a
            Spanish population
  JOURNAL   Thyroid 20 (7), 803-809 (2010)
   PUBMED   20578902
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474015.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_227527.3, XM_001065786.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB546918.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3417
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..3417
                     /gene="Wdr3"
                     /note="WD repeat domain 3"
                     /db_xref="GeneID:310720"
                     /db_xref="RGD:1307480"
     exon            1..50
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            51..253
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     CDS             83..2911
                     /gene="Wdr3"
                     /codon_start=1
                     /product="WD repeat-containing protein 3"
                     /protein_id="NP_001101175.1"
                     /db_xref="GeneID:310720"
                     /db_xref="RGD:1307480"
                     /translation="MGLTKQYLRYVASAVFGLIGSQKGNIVFVTLRGEKGRYVAVPAC
                     EHVFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGAIRVFSLLSGEGNIT
                     FNGHRAAVTSLKYDQLGGRLASGSKDTDVIIWDVINESGLYRLKGHKDAVTQALFLRE
                     RNLLVTSGKDTMVKWWDLDNQHCFKTMVGHRTEVWGLVLVSEETRLITGAADSELRAW
                     DIAYLQEIDDPEEPEPKKIKECPGIQDTPEAEDRTLEADDEKSEDRILSCRKAGSLMR
                     EGRDRVVNLAVDKTGRILACHGTDSVLEVFCILSKAEVQKKMDKKLKKARKKARLNSA
                     NEEEDPETSVSMTLQDEILRVTKIKTSAKIKSFDLIHSPQGELKAVFLLQNNLVELYS
                     LSTSLPNPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAAESVKIWNRSTLQCIRT
                     MPCEYALCSFFVPGDRQVVIGTKTGNMQLYDLASGNLLETIAAHDGALWSMSLSPDQR
                     GFVTGGADKAVKFWDFELVTDKNSTQKRLSVKQTRILQLDEDVLYVCYSPDQRLLAVS
                     LLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDC
                     HRSLFAHDDSVMHLRFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAV
                     SPSGDYVVSASHDKSLRLWERTREPLILEEERELQREAEYEESVAKEEQPAVPGETQG
                     DNYFTGKKTIETVKAAERIMEAIELYREETAKMKEHRAICRAAGKEVPLPVNPILMAH
                     GNISPSAYVLETFKGIRSSELEEALLVLPFSYVPDILTLFNGFIQTGSDVELLCRCLF
                     FLLRIHFGQITSNQMLVPVIEKLKETTISKVRQVQDVIGFNMAGLNYLKRECEAKSEV
                     MFFAEATSHLEEKKRKRKNRRKMILTLT"
     exon            254..463
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            464..582
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            583..661
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            662..757
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            758..871
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            872..973
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1071
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1176
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1407
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1408..1501
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1502..1603
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1604..1689
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1690..1825
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1826..1882
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1883..1983
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1984..2095
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            2096..2230
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            2231..2281
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            2282..2347
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            2348..2440
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            2441..2488
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            2489..2532
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            2533..2661
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            2662..2755
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
     exon            2756..3417
                     /gene="Wdr3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcgggtcc ggctggcggt gctgtctgct ggaacctcgt ggaggctgag attgcctccc
       61 ctgtggcatc agacatccta acatggggct taccaaacag tatctccgct atgtggctag
      121 tgctgtcttt ggcttgattg gcagccaaaa aggcaacatt gttttcgtga cactccgagg
      181 tgaaaaagga cgctacgtgg cagtacctgc ctgtgaacac gtttttatct gggacctaag
      241 gaaaggcgag aagatcctta tccttcaggg gcttaaacaa gaagtcactt gcttgtgtcc
      301 ctccccggat gggctgcatc tagctgttgg ctatgaggat ggagccatcc gagtcttcag
      361 cctcctcagt ggtgagggaa acataacctt caatggacac agagcagccg tcaccagctt
      421 aaagtacgat cagctaggag gcagactggc ttccgggtct aaggatacgg atgtcattat
      481 ttgggatgtg atcaatgaaa gtggcctcta ccgtctaaag ggacacaagg atgccgtcac
      541 acaagctctg tttctccgag aaaggaatct gctagttaca agtgggaaag acactatggt
      601 gaagtggtgg gacctggata accagcactg cttcaaaaca atggttggcc accgaactga
      661 ggtgtggggc ttggttctgg tttcagaaga aactcgacta atcactgggg ctgcagacag
      721 tgagctgaga gcctgggaca tcgcctatct acaggagatt gatgacccag aagaaccaga
      781 gcccaagaaa atcaaagagt gtccagggat acaggacacg cctgaagcag aggaccgcac
      841 ccttgaggcg gatgatgaga agtctgaaga ccgcatactc tcatgtagaa aagctggctc
      901 cttaatgcga gaaggaagag acagagttgt gaaccttgcc gtggacaaga caggccggat
      961 ccttgcttgc cacggaactg attctgtgtt agaagtattt tgtattcttt ccaaagcaga
     1021 agttcagaag aaaatggata aaaagctaaa gaaagctaga aagaaagcaa gattgaactc
     1081 tgccaatgag gaggaggacc ctgaaacaag tgtctcaatg actctgcagg atgagatcct
     1141 tcgggtaacc aagatcaaga cttctgccaa gatcaaatct tttgacctga ttcattcgcc
     1201 tcaaggagag ttaaaggcag tcttcctgct gcagaacaat ctggtagaac tgtattcgct
     1261 cagtacatcc ttgccaaacc cccagcctgt gaggacgagc aggatcacca tcggaggcca
     1321 ccgcagcgat gtgcgcacgc tgtctttcag ctcggataac atagctgtgc tttcagccgc
     1381 agccgagtcc gttaagatat ggaacaggtc taccctgcag tgcatccgca ccatgccttg
     1441 tgaatatgct ctctgctcct tctttgttcc tggtgacagg caggtggtca tcgggacaaa
     1501 gacaggaaat atgcaacttt atgacctggc ctcgggcaat ctcttggaga caatagctgc
     1561 ccatgatgga gctctgtggt ccatgtctct ttctccagat cagcgtggct ttgtgacagg
     1621 tggtgctgat aaagctgtca agttctggga ttttgagttg gtgacagata aaaatagtac
     1681 ccagaagaga ctctctgtga aacaaactag aatcttgcag ctagatgagg atgtcctata
     1741 tgtctgctac tctcctgatc aaaggctgct ggctgtatct ttgctggact gcactgtgaa
     1801 gattttctat gttgacactt taaagttttt tctctcactg tatggacaca agctgcctgt
     1861 tatatgcatg gacatctccc atgatggagc actaatagca actggttctg ctgatagaaa
     1921 tgtgaaaatc tggggtctgg actttgggga ctgccacagg tctctctttg cacatgatga
     1981 cagtgtgatg catctccgat tcgtgcccaa gtcccacctt ttcttcaccg cggggaagga
     2041 ccacaagatc aagcagtggg atgcggacaa gtttgagcac atccaaacgc tggaggggca
     2101 tcaccaggaa atatggtgtt tggctgtcag ccctagtgga gactacgtgg tgtcagcctc
     2161 tcatgacaag tctctgagac tctgggagag aacgagagag cctcttattc ttgaggaaga
     2221 aagggaactg caaagggaag cagagtatga ggagagtgtg gccaaagaag agcagccagc
     2281 agttccaggg gagacccagg gtgacaacta cttcactggg aagaagacaa ttgaaacagt
     2341 caaagcggct gagaggatca tggaggcaat tgagctgtac cgagaagaaa ctgcaaaaat
     2401 gaaagaacac agagccattt gtagagcagc ggggaaagag gttcctcttc ctgtcaaccc
     2461 catcctgatg gcccatggca atatttctcc ctcagcgtat gtgttagaga cttttaaagg
     2521 gatcaggtca agtgaactgg aagaggccct gcttgtgctg ccgttctcct atgtcccaga
     2581 cattcttacg ctgttcaatg ggttcatcca gacaggatca gatgtcgagc tgttgtgccg
     2641 gtgcctcttt tttctcctca ggattcactt tggccagatc accagcaacc agatgcttgt
     2701 gcccgtgata gagaagctaa aagaaacaac tatttcaaaa gtcagacaag tccaggatgt
     2761 cattggcttc aatatggctg gtctcaatta tcttaagaga gaatgcgaag caaagagtga
     2821 agttatgttt tttgcagaag ctactagtca cttggaagag aagaagagaa aacgaaaaaa
     2881 tagaagaaag atgattttaa cactgactta gaactggagt gctatatctt ttcctgcttc
     2941 tcttctaagg agcgttcaca taaactgtgg gcaacatctt aaaaataccg aaaaagaaga
     3001 tcatgttgta gatcttgggg tatagaagtc agccttggct gaagaaaccc aacatggctg
     3061 tgagttctgt cttccatctt ttgaaagaaa cagatttagt ttaaaaaatc tgtatttttc
     3121 agagttggac ctttaaatta cagcaagaaa gaaaagaata tttttaattg tgtatttgat
     3181 tcattcagaa gtgtgaattt tatttatggc agattatttg tattagagct tttccattca
     3241 gcatgtgtgt ctttgtcttc taaaggaaga atcatggact gtggggctgg agggatgatg
     3301 ggatgcctgg ggaagcctcc ttacaccatg caggttgttg agtctgcatg taagatcatg
     3361 atgctgtttg tacttctggg aatacaatag ctttttcatt aaaaccactt aaaataa
//
