LOCUS       NM_001127537            2646 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Rattus norvegicus WD repeat containing planar cell polarity
            effector (Wdpcp), mRNA.
ACCESSION   NM_001127537 XM_001056634 XM_223660
VERSION     NM_001127537.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2646)
  AUTHORS   Toriyama,M., Lee,C., Taylor,S.P., Duran,I., Cohn,D.H., Bruel,A.L.,
            Tabler,J.M., Drew,K., Kelly,M.R., Kim,S., Park,T.J., Braun,D.A.,
            Pierquin,G., Biver,A., Wagner,K., Malfroot,A., Panigrahi,I.,
            Franco,B., Al-Lami,H.A., Yeung,Y., Choi,Y.J., Duffourd,Y.,
            Faivre,L., Riviere,J.B., Chen,J., Liu,K.J., Marcotte,E.M.,
            Hildebrandt,F., Thauvin-Robinet,C., Krakow,D., Jackson,P.K. and
            Wallingford,J.B.
  CONSRTM   University of Washington Center for Mendelian Genomics
  TITLE     The ciliopathy-associated CPLANE proteins direct basal body
            recruitment of intraflagellar transport machinery
  JOURNAL   Nat Genet 48 (6), 648-656 (2016)
   PUBMED   27158779
  REMARK    Erratum:[Nat Genet. 2016 Jul 27;48(8):970. doi:
            10.1038/ng0816-970b.. PMID: 27463398]
REFERENCE   2  (bases 1 to 2646)
  AUTHORS   Cui,C., Chatterjee,B., Lozito,T.P., Zhang,Z., Francis,R.J.,
            Yagi,H., Swanhart,L.M., Sanker,S., Francis,D., Yu,Q., San
            Agustin,J.T., Puligilla,C., Chatterjee,T., Tansey,T., Liu,X.,
            Kelley,M.W., Spiliotis,E.T., Kwiatkowski,A.V., Tuan,R.,
            Pazour,G.J., Hukriede,N.A. and Lo,C.W.
  TITLE     Wdpcp, a PCP protein required for ciliogenesis, regulates
            directional cell migration and cell polarity by direct modulation
            of the actin cytoskeleton
  JOURNAL   PLoS Biol 11 (11), e1001720 (2013)
   PUBMED   24302887
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC161962.1.
            
            On or before May 23, 2008 this sequence version replaced
            XM_001056634.1, XM_223660.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161962.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2646
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q22"
     gene            1..2646
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /note="WD repeat containing planar cell polarity effector"
                     /db_xref="GeneID:305552"
                     /db_xref="RGD:1309501"
     exon            1..260
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            261..345
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     CDS             285..2465
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /codon_start=1
                     /product="WD repeat-containing and planar cell polarity
                     effector protein fritz homolog"
                     /protein_id="NP_001121009.1"
                     /db_xref="GeneID:305552"
                     /db_xref="RGD:1309501"
                     /translation="MSFCLTELHLWSLKSTLHIADRDIGVYQYYDKKDLPVSAAEHGN
                     LEEKQRLAESRDYPWTLKNRRPEKLRDSLKELEELMQNSQCVLCQWKSKHICQLLFGS
                     GVLVSLSLSGPQLEKVVIDRSLVGKLISDTISDALLTDSFIILSFLAQNKLCFIQFAK
                     KMDSLDVNKRLEKLSALDYKISYHDIPGPATRTVDRHLAINSTQDLAVCWWPLLSDDA
                     WPWTPIASEKDRANMLLLGFTQGGLEVLSSVRTEWNPLDVHFGTRQPYQVFTVECSFS
                     VDQEPMADSCIYESVRNKLHCVSVTRIPLRSKAISCCKNSTEDKLIVGCEDSSVILYE
                     AHRGVTLLAQAELMPSLISCHPSGAILLVGSNQGELQVFDIALSPINIQLLAEDCLPK
                     ETLQFNKFFDFSSSLVHMQWIAPPIVFQKPKRGEICDLLFLRFNRGPLGVLLFKLGVL
                     RRGQLGLVDLIFQYIHCDEVYEAVSVLSSMNWDTLGQQCFISMSTIVNHLLRQRLTPE
                     REAQLEASLGTFYAPARPLLDTTVLAYRDPVGTYARRLFHHLLRYQRFEKAFLLAVDI
                     GARDLFMDIHYLALDMGELALAEVARRRADDIDVESVCSGVELLGPLDRRDMLNEGFA
                     GSALTPEGGNPFPDLLPSSGSTPKHTIQQKIPNGPSNRRAIERKNEVMEETEEEEEEE
                     EEAAACTDSSVATTWDAEGELREDHRRQDTEDVGSLRMVHFGLV"
     exon            346..393
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            394..444
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            445..515
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            516..575
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            576..690
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            691..824
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            825..1016
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1626
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            1627..1815
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            1816..1939
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            1940..2003
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            2004..2106
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            2107..2269
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            2270..2385
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            2386..2414
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
     exon            2415..2622
                     /gene="Wdpcp"
                     /gene_synonym="RGD1309501"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacagcaccc gccactccac cgagaatcta tcctccccca agactaaaca agggaggcaa
       61 agagaccttc cgttgcaaaa aaaaaaaagc cagctcgacc cggaaacaaa accttttaaa
      121 aacgcactct ctcagaggcg ggaggaattg acgcttgcgg aggaaccggc agcttcaccg
      181 ttgctaggcg acagggaagg ctcacctgaa cgctctcgga accgagacag agtggagctg
      241 cgtccccacg cctgaagcag gacagagatt tcctccgctg tcagatgtct ttctgcttga
      301 ctgaactgca cctgtggtct ctgaaaagca ccttacacat tgcggataga gacatcggcg
      361 tctaccagta ctatgacaag aaagatctac cagtatcagc agcagagcat ggtaacttag
      421 aagaaaaaca aaggctggca gaatcacgag attatccttg gacactcaaa aatagacgcc
      481 cagaaaaact tcgagattca ctgaaagagt tggaggaact gatgcagaac agtcagtgtg
      541 tgctgtgcca atggaagagc aaacacatct gtcagctcct ctttggttca ggtgtgctgg
      601 tgtccctaag cctttctggg cctcagctgg agaaagtggt gattgacagg agcctggtgg
      661 ggaagctcat ctcagacacc atcagtgatg ctctccttac agacagtttc atcatcttat
      721 catttctggc acaaaacaaa ttatgtttta ttcaatttgc aaagaagatg gattctcttg
      781 atgtaaacaa gaggttggaa aagctctcag ccttggatta taagatttcc taccatgaca
      841 tacctggccc agccaccagg acagtagatc gtcacttagc catcaactcc actcaggatc
      901 tagctgtttg ctggtggcct ctgctcagcg atgatgcttg gccttggact ccgatcgctt
      961 ctgagaagga cagagccaat atgctgctcc tgggctttac tcaaggagga ttggaggtcc
     1021 tgagctctgt tcgcacagaa tggaatcctc tggatgttca ctttggcacc agacaacctt
     1081 atcaggtgtt cacagtggag tgctccttca gtgtagacca ggagcccatg gctgacagct
     1141 gtatctacga gtctgtccgg aacaaactcc attgcgtgtc agttactaga ataccactaa
     1201 ggtcgaaggc catcagctgc tgtaagaatt ctacggaaga caaactgatt gtgggctgtg
     1261 aagactcgtc cgtaattctc tatgaagctc accgtggagt gactctcttg gcccaggctg
     1321 aacttatgcc ttcattaata agctgccacc caagtggtgc cattctgctg gttggcagca
     1381 accaagggga attacaagtt tttgacattg ctctgtcccc tatcaacatc cagctcttgg
     1441 cagaagattg cttaccaaag gagactctgc aattcaataa attctttgat ttttccagca
     1501 gtcttgttca tatgcagtgg atagctcctc ccattgtttt ccagaagcct aagagaggag
     1561 aaatctgtga tctcctcttc ctcaggttca acagaggacc tttgggtgtg ctgttgttta
     1621 aacttggtgt cctcaggcga gggcagctgg gcctggtgga ccttatcttc cagtacattc
     1681 actgtgatga ggtgtacgag gccgtcagcg ttctgagcag catgaactgg gacaccctgg
     1741 ggcagcagtg cttcatcagc atgagcacca ttgtgaacca tcttctcaga cagaggctca
     1801 ctccggagag ggaagcacag cttgaggcaa gccttggaac cttctatgct ccagcgagac
     1861 cgcttctgga tacaactgtt ctggcataca gagacccggt tggcacgtac gccaggaggc
     1921 tcttccacca cttgctcagg taccagagat ttgaaaaggc ctttcttcta gcggttgaca
     1981 ttggagctcg tgacctgttc atggatattc attaccttgc cctggatatg ggtgagctgg
     2041 cactggctga agtggcaaga agaagggcag atgacattga tgtcgagtca gtgtgctctg
     2101 gagtcgaact cctgggaccc ttggacagaa gagacatgct gaatgaaggt tttgccggct
     2161 cagctttaac acctgaagga ggaaacccat ttccagacct tcttccttcc agtggttcaa
     2221 cacccaagca tactattcaa cagaaaatac caaatggccc ttcaaacaga cgggcaattg
     2281 aaagaaagaa tgaggtgatg gaggagacag aggaggaaga ggaggaggag gaggaggcag
     2341 cggcctgcac tgactcttca gtggctacca cctgggatgc agaaggagaa ctgagggaag
     2401 accacaggag acaggacact gaagatgttg gttctctcag aatggttcac tttggtttgg
     2461 tgtaatgatt agaaacacca aaaagaaagc tgtccttttt atatcttttc tattgacctt
     2521 atcaacaaaa gtcttcacgc atggactgta gtagaaggaa agctagtgca tgcagcacag
     2581 cgtaacatag ctaagcagcc ctcagtaaaa gttcctaaac aaaaaaaaaa aaaaaaaaaa
     2641 aaaaaa
//
