LOCUS       NM_001393984            4333 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus WD repeat and FYVE domain containing 1 (Wdfy1),
            transcript variant 1, mRNA.
ACCESSION   NM_001393984 XM_006245190
VERSION     NM_001393984.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4333)
  AUTHORS   Hu,Y.H., Zhang,Y., Jiang,L.Q., Wang,S., Lei,C.Q., Sun,M.S.,
            Shu,H.B. and Liu,Y.
  TITLE     WDFY1 mediates TLR3/4 signaling by recruiting TRIF
  JOURNAL   EMBO Rep 16 (4), 447-455 (2015)
   PUBMED   25736436
REFERENCE   2  (bases 1 to 4333)
  AUTHORS   Ridley,S.H., Ktistakis,N., Davidson,K., Anderson,K.E., Manifava,M.,
            Ellson,C.D., Lipp,P., Bootman,M., Coadwell,J., Nazarian,A.,
            Erdjument-Bromage,H., Tempst,P., Cooper,M.A., Thuring,J.W.,
            Lim,Z.Y., Holmes,A.B., Stephens,L.R. and Hawkins,P.T.
  TITLE     FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct
            functions in the endosomal and Golgi compartments
  JOURNAL   J Cell Sci 114 (Pt 22), 3991-4000 (2001)
   PUBMED   11739631
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Mar 25, 2021 this sequence version replaced XM_006245190.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643291.26090.1,
                                           SRR26360172.1739010.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760389,
                                           SAMEA5760434 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-176               JAXUCZ010000009.1  88541011-88541186   c
            177-244             JAXUCZ010000009.1  88518473-88518540   c
            245-318             JAXUCZ010000009.1  88511839-88511912   c
            319-373             JAXUCZ010000009.1  88507568-88507622   c
            374-524             JAXUCZ010000009.1  88505062-88505212   c
            525-637             JAXUCZ010000009.1  88503209-88503321   c
            638-764             JAXUCZ010000009.1  88501034-88501160   c
            765-870             JAXUCZ010000009.1  88499829-88499934   c
            871-972             JAXUCZ010000009.1  88495746-88495847   c
            973-1103            JAXUCZ010000009.1  88494606-88494736   c
            1104-1212           JAXUCZ010000009.1  88493123-88493231   c
            1213-4333           JAXUCZ010000009.1  88489227-88492347   c
FEATURES             Location/Qualifiers
     source          1..4333
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q34"
     gene            1..4333
                     /gene="Wdfy1"
                     /note="WD repeat and FYVE domain containing 1"
                     /db_xref="GeneID:301549"
                     /db_xref="RGD:1305996"
     exon            1..176
                     /gene="Wdfy1"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..1272
                     /gene="Wdfy1"
                     /codon_start=1
                     /product="WD repeat and FYVE domain-containing protein 1"
                     /protein_id="NP_001380913.1"
                     /db_xref="GeneID:301549"
                     /db_xref="RGD:1305996"
                     /translation="MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASE
                     DRTIRVWLKRDSGQYWPSIYHTMASPCSAMAYHHDSRRVFVGQDNGAVMEFHVSEDFN
                     KMNFIKTYPAHQNRVSAIVFSLAAEWVVSTGHDKCVSWMCTRSGNMLGRHFFSSWASC
                     LQYDLDTQHAFVGDYSGQITLLKLEQNSCSVITTLKGHEGSIACLWWDPIQRLLFSGA
                     SDNSIIMWDIGGRKGRTLLLQGHHDRVQSLCYLQLTRQLVSCSADGGIAVWNMDVSRE
                     EAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQAVCGKCSSKRSSYPV
                     MGFEFQVRVCDSCYDSIKDEDRTSLATFHEGKHNISHMSMDIARGLMVTCGTDRVVKI
                     WDMTPVVGCSLATGFSPH"
     exon            177..244
                     /gene="Wdfy1"
                     /inference="alignment:Splign:2.1.0"
     exon            245..318
                     /gene="Wdfy1"
                     /inference="alignment:Splign:2.1.0"
     exon            319..373
                     /gene="Wdfy1"
                     /inference="alignment:Splign:2.1.0"
     exon            374..524
                     /gene="Wdfy1"
                     /inference="alignment:Splign:2.1.0"
     exon            525..637
                     /gene="Wdfy1"
                     /inference="alignment:Splign:2.1.0"
     exon            638..764
                     /gene="Wdfy1"
                     /inference="alignment:Splign:2.1.0"
     exon            765..870
                     /gene="Wdfy1"
                     /inference="alignment:Splign:2.1.0"
     exon            871..972
                     /gene="Wdfy1"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1103
                     /gene="Wdfy1"
                     /inference="alignment:Splign:2.1.0"
     exon            1104..1212
                     /gene="Wdfy1"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..4333
                     /gene="Wdfy1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agctgatggg ccgcccgcgg gggaggccgc ggctcgaaca tggcggccga gatccactcc
       61 aggccgcaga gcagccgccc ggtgctgctg agcaagattg agggccacca ggacgccgtc
      121 accgcagcgc ttctcatccc caaggaggac ggcgtgatca ccgctagcga ggacagaacc
      181 atcagagtat ggctgaaaag agacagcggc cagtactggc ccagcatcta ccacacaatg
      241 gcctctcctt gctctgccat ggcttaccat cacgacagca gacgggtgtt tgtgggccag
      301 gataacgggg ctgtaatgga atttcacgtt tctgaagatt ttaataaaat gaattttatc
      361 aagacctatc cagctcatca gaaccgagtg tctgccatcg tcttcagctt ggctgccgag
      421 tgggtggtca gcacgggcca cgacaagtgt gtgagctgga tgtgcacgcg cagcgggaac
      481 atgcttggcc gtcacttctt ctcgtcatgg gcttcctgtc tgcagtacga tctggatact
      541 cagcatgcat ttgtgggcga ttactcggga cagatcaccc tgctgaagct ggagcagaac
      601 tcctgctcag ttatcaccac cctcaagggc catgaaggta gtatcgcctg cctttggtgg
      661 gaccctatcc agcggttact cttctcagga gcatccgaca acagcatcat catgtgggac
      721 atcgggggtc ggaaaggccg aacactcctc cttcagggcc accatgacag ggtgcagtca
      781 ctgtgctacc tgcagctcac caggcagctc gtctcctgct cggcggatgg cggaattgcg
      841 gtgtggaaca tggatgttag ccgagaagag gctcctcagt ggttagaaag cgattcctgt
      901 cagaagtgtg agcagccctt cttctggaat ataaagcaga tgtgggacac gaagacactg
      961 gggctgaggc agcatcactg caggaagtgt gggcaggccg tctgtgggaa gtgcagcagc
     1021 aagaggtcca gctaccctgt catgggcttt gagttccagg ttcgagtttg tgattcctgt
     1081 tatgactcca tcaaagatga ggaccgcact tctctagcaa cgtttcatga aggaaaacat
     1141 aacatttccc atatgtccat ggacattgcg aggggactga tggtgacctg tgggacagat
     1201 cgtgttgtaa agatatggga tatgactcct gtggtgggct gcagcctggc aactggattt
     1261 tctccacact gatcctggag ctggatggta cgtctgctac acgttacgca cagcaacctc
     1321 catgaaccga agcccttcat gtagctcagc agccgctgtc atgtaaatgg acagtagcca
     1381 cctaaaaaaa aacaaatcaa tatttttaaa aagaaaaaaa tacataaagg tgtgttctgg
     1441 ggtatttgtg gaaattatct ttggggagta acacccaaaa ggtctgtcca tacctgtctc
     1501 ctgaggaatg gaatttcctc agcaaaactg cctcatgatc attgagccag tgggtgagga
     1561 gggcacggcc agcaagtgaa gggtttagaa ggaaaatgtc tgaacaaaaa gaatagtgct
     1621 tagaactgct taaatgcaaa cccaagagca cacatggagt ctaccgagcc ggtcctcgag
     1681 gcccctgaga gcactccaat atgcaatcag gagctggggg aagagctctt cttcagggga
     1741 ggcaaccagc tataacaagc ctaagcttgt catacaaatg atctctacac caggttgctg
     1801 atcactcctt caaggcacct gttctgtcag gtctcctcct gatctgctct tgggtttggc
     1861 tcactgcagt tgtttctgtc ccagccagtg tcccatgggt gaacctttac agctgtcata
     1921 taacaagaca gcacacatcc atctctttct cccaaacctg ctctgtggac aaagctttct
     1981 tttatggtgc tgttgtacaa gcctcctgac ttttttttct ttgtagctag tcatgaccca
     2041 tggcaaactc agccaccgcc atggtggtga tgggtgccag cagcccagtc catggaacag
     2101 cccagtcttg ctaactgata catttgtttg cagtcccagg acaagccctt gtgatatggt
     2161 agcaatttat gcccctcaga agtactctgg agcttttata ttctgttgta gcagccaatg
     2221 ttactcatgt gtcataggaa gaaatcggtg gcccattgca gaaattatca gtcaggtctt
     2281 gtacagtaat ccctaacttg taaatcactt ttataacatt tagaaaaact gttgtatgaa
     2341 atgtgttgtc caagttttga ccagattacc aggagatgtt tatgtatttt tgtgttgaca
     2401 gaaagtagca catgaactat ttcagtagag ccgcgggagc ctgctgcttt ccagtaggaa
     2461 agggctactg ggttaaagga taaatcatga atacccacag catctgggtg actcttgctg
     2521 ctgggtatca atttaaaatc tcactgtgcc actttgttgg attacgtcaa gatcagggcc
     2581 attctgccag acaggactaa ggcttaatca ctttatcaac atggcttaca aggaggggaa
     2641 actctgtaac aggcagtaaa gctatgatgt cccaatggac aagacacaaa tggtaaggaa
     2701 aggaaaggca gcaggcataa cgggctctat ttgtagagag ctcttaactt cagaaataag
     2761 accaaagggt tttgttgccc cctttaaatt ttatgtcact ttaactgatg atctttcacc
     2821 ggatttccct tacactgcac gaaatgtgca ttgctggagt gctctggaca agagagtggg
     2881 tgatgttttg aaaccacaat gtagaatgtt ctccttgctc tgctcgtttt agctcaccct
     2941 atgattctgc ccatacaagg gaaatagacc ttggcagagt cattgccctg tggaatagtg
     3001 ctgagctgtg tgtggtttta ttgtcctaaa agcatctgta aaatgtgact tttggatatc
     3061 tgtggtagtc tctttctcct ttttaaagcc tcttaatgta aaaccccatg ccccatagaa
     3121 agcatgtagt tggtttgagc cttttagggg gctaatagaa atccaggggg aaattatatt
     3181 aaggaagaat tagggggagg ggcctttgga gggaatgcag gctctttgaa tgcactttgc
     3241 tcctcacttg agcctgtggt catggtctcc tttcggaagt gttcttgtca ggctcccctt
     3301 acgtgtcaca cgtcaggtaa caaagggggt catattttct atagagggtg aagattatag
     3361 tctcaagttt actgactgaa gggacagcaa ggctcatggt ctttgcctta tttggactct
     3421 gttgctaaac agaccactta aaagagttcc tcaagaaaca gctactgtcc tttcacaaga
     3481 cagtttgtac agacaaggat caagaagtag aggatgttag acaagagcct tgaacttaga
     3541 tctagtatgt aataaagtga tgccaagcct ttattctcaa tgtgttcttt aatggtcctt
     3601 tattagttgg tcctagtgtt agtagtaggc ctgtaccttg gtagaaacca cttcttactc
     3661 actagactgt aattgtttac tatgtcccgg tcttaacttg ctgcctagtg gacagaatag
     3721 acactgttgc tgtagactgt tgctttgttc tcccgcacag tgattcggtt tgttaacatc
     3781 tgtatttatt aaatgtcaaa atgggtaaat agaatagcag ctcagatcca agaagatatt
     3841 tttgaaaatc agggtttcat taaaagtact tttcatatct cctaaatgac aagtatcaag
     3901 ttactattaa tgaaaatgat ctgctcatga taaatggagg cttaacaaat aagtaataca
     3961 tgctaatctc tgccgtgtct gtgcttagtt gttaatgtga gcagatattg aatgcctctc
     4021 tattttctgc cgtttactac acagtaactc tttgagtaag ttgaagttta attgtgcagc
     4081 aaatttctat caaagaacaa tttaaagtgt tttactctgt aacctttttt tccccgactc
     4141 ggaaagcaaa aggtgacata aagtaattca gtttgtcctt gcacagctgt gtttccatag
     4201 agttgggcgc cctgtgtatc ctagagacgc taaaattctt gttctttcta cttgtgggtt
     4261 ccatctttgt ggggcttttt agtttttgtt ttgagaatac acatataata aaataccctt
     4321 tgcttgttcc tta
//
