LOCUS       NM_001106776            1039 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus WASH complex subunit 3 (Washc3), mRNA.
ACCESSION   NM_001106776 XM_001079910 XM_216873
VERSION     NM_001106776.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1039)
  AUTHORS   Tyrrell BJ, Woodham EF, Spence HJ, Strathdee D, Insall RH and
            Machesky LM.
  TITLE     Loss of strumpellin in the melanocytic lineage impairs the WASH
            Complex but does not affect coat colour
  JOURNAL   Pigment Cell Melanoma Res 29 (5), 559-571 (2016)
   PUBMED   27390154
REFERENCE   2  (bases 1 to 1039)
  AUTHORS   Gallon M and Cullen PJ.
  TITLE     Retromer and sorting nexins in endosomal sorting
  JOURNAL   Biochem Soc Trans 43 (1), 33-47 (2015)
   PUBMED   25619244
  REMARK    Review article
REFERENCE   3  (bases 1 to 1039)
  AUTHORS   Derivery E, Sousa C, Gautier JJ, Lombard B, Loew D and Gautreau A.
  TITLE     The Arp2/3 activator WASH controls the fission of endosomes through
            a large multiprotein complex
  JOURNAL   Dev Cell 17 (5), 712-723 (2009)
   PUBMED   19922875
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473960.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001079910.1, XM_216873.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CF110590.1, FM069272.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1039
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..1039
                     /gene="Washc3"
                     /gene_synonym="Ccdc53; RGD1563761"
                     /note="WASH complex subunit 3"
                     /db_xref="GeneID:299707"
                     /db_xref="RGD:1563761"
     exon            1..198
                     /gene="Washc3"
                     /gene_synonym="Ccdc53; RGD1563761"
                     /inference="alignment:Splign:2.1.0"
     CDS             148..732
                     /gene="Washc3"
                     /gene_synonym="Ccdc53; RGD1563761"
                     /note="WASH complex subunit CCDC53; coiled-coil domain
                     containing 53"
                     /codon_start=1
                     /product="WASH complex subunit 3"
                     /protein_id="NP_001100246.1"
                     /db_xref="GeneID:299707"
                     /db_xref="RGD:1563761"
                     /translation="MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRF
                     SAVCEEKLADLSLRIQQIETTLNILDAKLSSIPGLEDVTVDMSPLSVTAVTNGSHSET
                     TAEQLQQNSTQDSGVQQGEAPSENVLTVAKDPRYARYLKMVQVGVPVMAIRDKMISEG
                     LDPELLEKPDAPVPSGESEKAIEESSESESSFSD"
     exon            199..297
                     /gene="Washc3"
                     /gene_synonym="Ccdc53; RGD1563761"
                     /inference="alignment:Splign:2.1.0"
     exon            298..363
                     /gene="Washc3"
                     /gene_synonym="Ccdc53; RGD1563761"
                     /inference="alignment:Splign:2.1.0"
     exon            364..471
                     /gene="Washc3"
                     /gene_synonym="Ccdc53; RGD1563761"
                     /inference="alignment:Splign:2.1.0"
     exon            472..582
                     /gene="Washc3"
                     /gene_synonym="Ccdc53; RGD1563761"
                     /inference="alignment:Splign:2.1.0"
     exon            583..647
                     /gene="Washc3"
                     /gene_synonym="Ccdc53; RGD1563761"
                     /inference="alignment:Splign:2.1.0"
     exon            648..1039
                     /gene="Washc3"
                     /gene_synonym="Ccdc53; RGD1563761"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctccgaag ccaccgattg attggtgaac acacgcgctc tcttccggaa aggccccgaa
       61 ggcaggaact tgggaaagga gtctggtctc tctaccaggc tgggaggagc ttgtgcctga
      121 gccccggggt ccccatccgc tgaggagatg gatgaggatg ggcttcctct catggggtca
      181 ggcatagacc tgaccaaggt gccagctatt caacagaaaa gaaccgtggc ttttctaaac
      241 cagtttgtgg tgcacactgt gcagtttctc aaccggtttt ccgcagtttg tgaagagaaa
      301 ctggcagacc tttctcttcg gattcaacaa attgaaacaa ctctcaatat tttagatgcg
      361 aagctgtcat ctatcccagg cctagaggat gtcacagttg acatgtctcc tttaagtgtc
      421 actgctgtca caaatggatc acattctgaa accactgctg agcaactgca gcagaacagc
      481 acgcaagact ccggagtaca acaaggtgaa gcgccatcag aaaatgtcct aactgtagcc
      541 aaggacccac gatatgccag atacctcaag atggttcaag tgggtgttcc ggtgatggca
      601 atcagagaca agatgatctc agaaggacta gacccagagc tactggagaa gccagatgct
      661 ccggtgccga gtggcgagag tgaaaaagcc atagaagaaa gttcagagag tgagtcttcc
      721 ttcagtgact aagctgtgag aatcacagaa cgtggaaggg tggatttatg ttctaggaac
      781 gagcgtaaac tctagctctc ggtgagagaa atcaccacat gctatgctac atacctaccc
      841 cagccttcct gtttaaaaat gataataaag catttataat ctttcagtat tgcttgttga
      901 ccaaataaaa tgccctgaaa ttaaaaatag gacaacatat attgctacaa gtgctatgaa
      961 cagtaggatg ggttcaggga acattctaaa atggagttcc tgtaggttta ctgatcaaaa
     1021 atagacttca cgtaaaaat
//
