LOCUS       NM_199207               4256 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus WASH complex subunit 2C (Washc2c), mRNA.
ACCESSION   NM_199207 XM_232289 XM_238371
VERSION     NM_199207.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4256)
  AUTHORS   McNally,K.E., Faulkner,R., Steinberg,F., Gallon,M., Ghai,R.,
            Pim,D., Langton,P., Pearson,N., Danson,C.M., Nagele,H.,
            Morris,L.L., Singla,A., Overlee,B.L., Heesom,K.J., Sessions,R.,
            Banks,L., Collins,B.M., Berger,I., Billadeau,D.D., Burstein,E. and
            Cullen,P.J.
  TITLE     Retriever is a multiprotein complex for retromer-independent
            endosomal cargo recycling
  JOURNAL   Nat Cell Biol 19 (10), 1214-1225 (2017)
   PUBMED   28892079
REFERENCE   2  (bases 1 to 4256)
  AUTHORS   Tyrrell,B.J., Woodham,E.F., Spence,H.J., Strathdee,D., Insall,R.H.
            and Machesky,L.M.
  TITLE     Loss of strumpellin in the melanocytic lineage impairs the WASH
            Complex but does not affect coat colour
  JOURNAL   Pigment Cell Melanoma Res 29 (5), 559-571 (2016)
   PUBMED   27390154
REFERENCE   3  (bases 1 to 4256)
  AUTHORS   Follett,J., Bugarcic,A., Yang,Z., Ariotti,N., Norwood,S.J.,
            Collins,B.M., Parton,R.G. and Teasdale,R.D.
  TITLE     Parkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal
            Association of Retromer and Induces alpha-Synuclein Aggregation
  JOURNAL   J Biol Chem 291 (35), 18283-18298 (2016)
   PUBMED   27385586
REFERENCE   4  (bases 1 to 4256)
  AUTHORS   Gallon,M. and Cullen,P.J.
  TITLE     Retromer and sorting nexins in endosomal sorting
  JOURNAL   Biochem Soc Trans 43 (1), 33-47 (2015)
   PUBMED   25619244
  REMARK    Review article
REFERENCE   5  (bases 1 to 4256)
  AUTHORS   McGough,I.J., Steinberg,F., Gallon,M., Yatsu,A., Ohbayashi,N.,
            Heesom,K.J., Fukuda,M. and Cullen,P.J.
  TITLE     Identification of molecular heterogeneity in
            SNX27-retromer-mediated endosome-to-plasma-membrane recycling
  JOURNAL   J Cell Sci 127 (Pt 22), 4940-4953 (2014)
   PUBMED   25278552
REFERENCE   6  (bases 1 to 4256)
  AUTHORS   Harbour,M.E., Breusegem,S.Y. and Seaman,M.N.
  TITLE     Recruitment of the endosomal WASH complex is mediated by the
            extended 'tail' of Fam21 binding to the retromer protein Vps35
  JOURNAL   Biochem J 442 (1), 209-220 (2012)
   PUBMED   22070227
REFERENCE   7  (bases 1 to 4256)
  AUTHORS   Harbour,M.E., Breusegem,S.Y., Antrobus,R., Freeman,C., Reid,E. and
            Seaman,M.N.
  TITLE     The cargo-selective retromer complex is a recruiting hub for
            protein complexes that regulate endosomal tubule dynamics
  JOURNAL   J Cell Sci 123 (Pt 21), 3703-3717 (2010)
   PUBMED   20923837
REFERENCE   8  (bases 1 to 4256)
  AUTHORS   Jia,D., Gomez,T.S., Metlagel,Z., Umetani,J., Otwinowski,Z.,
            Rosen,M.K. and Billadeau,D.D.
  TITLE     WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome
            protein (WASP) family are controlled by analogous structurally
            related complexes
  JOURNAL   Proc Natl Acad Sci U S A 107 (23), 10442-10447 (2010)
   PUBMED   20498093
REFERENCE   9  (bases 1 to 4256)
  AUTHORS   Derivery,E., Sousa,C., Gautier,J.J., Lombard,B., Loew,D. and
            Gautreau,A.
  TITLE     The Arp2/3 activator WASH controls the fission of endosomes through
            a large multiprotein complex
  JOURNAL   Dev Cell 17 (5), 712-723 (2009)
   PUBMED   19922875
REFERENCE   10 (bases 1 to 4256)
  AUTHORS   Gomez,T.S. and Billadeau,D.D.
  TITLE     A FAM21-containing WASH complex regulates retromer-dependent
            sorting
  JOURNAL   Dev Cell 17 (5), 699-711 (2009)
   PUBMED   19922874
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Nov 27, 2020 this sequence version replaced NM_199207.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY257251.1, SRR26643286.14573.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-85                JAXUCZ010000004.1  150940319-150940403
            86-208              JAXUCZ010000004.1  150940483-150940605
            209-373             JAXUCZ010000004.1  150941233-150941397
            374-436             JAXUCZ010000004.1  150949728-150949790
            437-610             JAXUCZ010000004.1  150954412-150954585
            611-704             JAXUCZ010000004.1  150956257-150956350
            705-766             JAXUCZ010000004.1  150957690-150957751
            767-811             JAXUCZ010000004.1  150959307-150959351
            812-919             JAXUCZ010000004.1  150959991-150960098
            920-1001            JAXUCZ010000004.1  150961098-150961179
            1002-1058           JAXUCZ010000004.1  150962506-150962562
            1059-1174           JAXUCZ010000004.1  150963188-150963303
            1175-1232           JAXUCZ010000004.1  150963727-150963784
            1233-1295           JAXUCZ010000004.1  150966371-150966433
            1296-1481           JAXUCZ010000004.1  150967236-150967421
            1482-1609           JAXUCZ010000004.1  150968991-150969118
            1610-1696           JAXUCZ010000004.1  150971813-150971899
            1697-1798           JAXUCZ010000004.1  150974913-150975014
            1799-1927           JAXUCZ010000004.1  150976824-150976952
            1928-2103           JAXUCZ010000004.1  150979385-150979560
            2104-2206           JAXUCZ010000004.1  150982953-150983055
            2207-2359           JAXUCZ010000004.1  150984388-150984540
            2360-2542           JAXUCZ010000004.1  150986079-150986261
            2543-2671           JAXUCZ010000004.1  150990830-150990958
            2672-2761           JAXUCZ010000004.1  150991064-150991153
            2762-2860           JAXUCZ010000004.1  150991688-150991786
            2861-2923           JAXUCZ010000004.1  150992673-150992735
            2924-3136           JAXUCZ010000004.1  150993054-150993266
            3137-3751           JAXUCZ010000004.1  150994884-150995498
            3752-3932           JAXUCZ010000004.1  150996295-150996475
            3933-4256           JAXUCZ010000004.1  150997978-150998301
FEATURES             Location/Qualifiers
     source          1..4256
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..4256
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /note="WASH complex subunit 2C"
                     /db_xref="GeneID:297530"
                     /db_xref="RGD:735230"
     exon            1..85
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             86..4072
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /note="WASH complex subunit FAM21; family with sequence
                     similarity 21, member C"
                     /codon_start=1
                     /product="WASH complex subunit 2"
                     /protein_id="NP_954677.2"
                     /db_xref="GeneID:297530"
                     /db_xref="RGD:735230"
                     /translation="MNRTSPDSEQPPASEPVWERPWSVEEIRRSSQNWSLAADAGLLQ
                     FLQEFSQQTISRTHEIKKQVDGLIQETKATHCRLHNVFNDFLMLSNTQFIENRVYDEE
                     VEDQALKTEAEKAEQEKTREQKEIDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSE
                     EEDANERVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIV
                     DSEDEKEEEESDDFASHSDNEQNQHITQMSDEEEDDDADLFADSEKEGDDIEDIEESA
                     KSKRPTSFADELAARIKGDVSNQRKEGHTDGKPQRTVKEKKERRTPADDEEDILFPPP
                     TLTDEDFSPFGSRGGLFSDRQGLFDDDDESDLFKEAPRGQPAQGPVSEESPPSPKPGK
                     KIPAGAVSVFLGYTDVSGSTSAPSLKEFQKHEQSTPGKGPHLPAPTGLFDDDDNDSDE
                     DDNFFMPSSSKPSKTDKVKPTTIIFDDDEGDLFKEKTTALPAASVSQTDENKARTDKT
                     ITLPSSKNPKLVSETKTQKGLFSDEEDSEDLFSSQSSSKTKSASVLSSQPPASVSLFG
                     DEDEEDNLFGSAAAKKQTSSLPPQSQEKAKPSEQPPKKASALFSSDEEDQWSVADSQT
                     KLASERKSKGERWDAGTNQGQEAKAVKKTNLFEEEDDDGVDLFAIAKDSQKKTQRTSL
                     LFEDDTDSGSSLFSLPPTSVPPAATKKESIPKVPLLFSDEEDSEVPSGVKPVDLKAEN
                     AAASPEVGSADVANVAQKEGLLPTSDQEAGGPSDIFSSSSPLDKGAKGRTKTVLSLFD
                     EDEDKVEDDSNTCAPQGGLEKGAKTDRRPKSTGVFQDEELLFSHKLQKDNDPDVDLFA
                     GTKKTRLSMPSGGSLFGDDDDDDLFSTAKTQPAQPVVPEKKGTLRKDHKPPELTEGSK
                     EKSTWKAETAQDSSGLTPFKSREPSSRIGKIQANLAINPATLLPSVAPQIPGAKPASS
                     ELAFPSSEPARSHIREAVPTLPGSEEAGVSFDLPAQADTLHSANKGRVKVRGKRRPQT
                     RAARRLAAQESSEAEDVIIDRGPVTQLSSSPVLPNGHQPLLQPRMASGETSSEKAMAV
                     PWEGGPVLSAVDRSFFVKSLPQTGNEAHLFDSGDIFPKSTGSQSMEGASVKAGETPAH
                     SSAGRKEKSLVFPDLSEASGVDDLFQSAKPRPTKKRNPFPLLEDEEDLFADQKGKKNQ
                     WKSDSHQDVVSKTQDIFEDDIFATEAIKKPFPKKREKERTLEPNLFDDNIDIFADLTV
                     KPKEKPKKKVTAKSMFDDDTDDIFSSGLQAKASKPKSQSAEAASELRSENQVSNIFDD
                     PLNAFGSQ"
     exon            86..208
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            209..373
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            374..436
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            437..610
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            611..704
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            705..766
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            767..811
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            812..919
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1001
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1058
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1174
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1175..1232
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1233..1295
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1481
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..1609
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1610..1696
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..1798
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1799..1927
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1928..2103
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2104..2206
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2207..2359
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2360..2542
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2543..2671
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2672..2761
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2762..2860
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2861..2923
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2924..3136
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3137..3751
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3752..3932
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3933..4256
                     /gene="Washc2c"
                     /gene_synonym="Fam21; Fam21c; NP61201; Washc2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtgactacc acagcgctgg gtgggcgctg ctggtagcag ctccggtagt cactttggac
       61 cttgctgagt agcggtgcaa acgtgatgaa ccggacgagc cccgactcgg agcagcctcc
      121 ggcgtccgaa cccgtgtggg aacggccctg gtcggtggag gagatccgcc gcagcagtca
      181 gaactggtcg ctggcggctg acgctggtct tctacagttt ctacaggagt tctcacagca
      241 gactatctcc aggactcacg aaatcaagaa gcaggtggat ggattaattc aggagaccaa
      301 ggccacacat tgtcgtctgc ataatgtctt caacgacttc ctcatgctgt ctaacaccca
      361 gttcattgag aatcgggtgt acgatgagga agtggaggat caggcgctca agacggaggc
      421 ggaaaaagct gagcaggaga agactcggga acagaaagaa atagatctga ttcctaaagt
      481 ccaggaggct gtgaactatg ggttacaggt cctggatagt gcgtttgagc aacttgacat
      541 aaaagcaggg aattcggact ctgaagagga agatgccaat gagcgggtgg aattgatcct
      601 tgagccaaag gacctctaca ttgaccggcc tttgccctac ctcatcgggt cgaagctctt
      661 catggaacag gaagacgtgg ggcttggaga gctgtccagc gaagaaggct ctgtgggcag
      721 tgaccgcggg agcattgtgg acagtgaaga tgagaaagaa gaggaggagt cagatgattt
      781 tgccagtcat agtgacaatg aacaaaacca gcatatcaca cagatgagtg acgaagaaga
      841 ggatgatgat gctgacctct ttgctgactc tgagaaggag ggggatgata tcgaggatat
      901 tgaggaaagt gctaagtcta aaagacctac gtcttttgcg gatgagctgg ctgctcggat
      961 caaaggagat gtctcaaacc agcggaaaga gggacacaca gatggaaagc ctcagaggac
     1021 agtgaaggag aagaaggaaa ggagaacccc tgcagatgat gaggaagaca tcttgttccc
     1081 accccccacg ctgactgatg aagacttctc accgtttggc tctagaggtg gtctgttcag
     1141 tgatcggcag gggctttttg atgatgatga tgagagtgac ctcttcaagg aagctccccg
     1201 ggggcagcca gcccaaggtc ctgtcagtga agaatcacct ccatccccta aacctggaaa
     1261 gaaaatccca gcaggggctg tttctgtatt tttagggtat actgatgtgt ctgggtccac
     1321 ctctgcccca tcactgaagg agttccagaa acatgagcag tccactccag ggaagggccc
     1381 acatttgcca gctcctactg gcctctttga tgatgatgat aacgacagtg atgaagatga
     1441 taactttttt atgccatctt ctagcaagcc ttctaagacc gacaaagtca agcccaccac
     1501 cattatcttt gatgatgacg aaggagatct gtttaaagaa aaaacaacag ctttgccagc
     1561 agcttctgtc agccagacag atgaaaacaa agcacggaca gataaaacga tcaccttacc
     1621 ttctagcaaa aatccgaagc ttgtatcaga aacaaagact cagaaaggtt tgttttcaga
     1681 tgaagaagac tctgaggatt tgttttcttc tcaaagttca agtaagacga aaagtgcatc
     1741 agttctgtcc agccaacccc cagcatcggt ctcccttttt ggtgatgaag atgaagagga
     1801 caatcttttt gggagtgcag cagctaagaa gcagacttca tctctgccac ctcagagtca
     1861 agagaaagca aaaccttcag agcagccccc aaagaaagca tctgccttgt tcagcagtga
     1921 cgaggaggac cagtggagtg ttgctgattc acagaccaag ttagcctccg agagaaagtc
     1981 caaaggagag aggtgggacg cggggaccaa ccaaggccaa gaagcgaagg ctgtgaaaaa
     2041 gaccaatctc tttgaggagg aggatgatga tggagtcgat ctctttgcta ttgcgaagga
     2101 cagccaaaag aagactcaga gaacctcact tctgtttgaa gatgacactg atagcggaag
     2161 ctctctgttc agccttcctc ctacatctgt tcctcctgca gcaacgaaaa aagagagcat
     2221 ccccaaggtg ccgttgttgt ttagtgatga agaggacagt gaggtaccat ctggtgtgaa
     2281 acctgtggat ctgaaggctg agaatgccgc ggcgtcccca gaggtgggga gtgctgatgt
     2341 ggccaatgtg gcacagaagg aaggactttt acccacatct gatcaggaag caggcgggcc
     2401 ttctgatata ttttcttctt catctccact ggacaaagga gccaagggta ggaccaaaac
     2461 tgtccttagt ttgtttgatg aggacgagga caaagtagaa gatgacagca acacctgtgc
     2521 gccacaaggt ggactggaaa agggtgccaa aactgaccgc cgccctaaga gcacaggagt
     2581 ctttcaggat gaagagctgc ttttcagcca caagctgcaa aaggacaacg acccagatgt
     2641 tgatcttttc gctggtacca aaaaaaccag gttgtccatg ccaagtgggg ggagcctctt
     2701 tggtgatgac gacgatgatg atctcttcag cactgccaag actcagcctg cacagcctgt
     2761 ggtaccagaa aaaaaaggaa cactgagaaa agaccacaaa cctcctgaat tgactgaagg
     2821 tagcaaagag aaaagcacat ggaaagcaga aacggcccag gattcttcag gtctcactcc
     2881 atttaaaagc agagagccat ccagtcgcat cgggaaaata caagcaaatt tagcaattaa
     2941 cccagccact ttgctgccct cagtggctcc gcagatcccc ggagcaaagc ctgcttcgtc
     3001 tgaactagct tttccttcat ctgagcctgc aaggagccac atccgggaag ctgtgcccac
     3061 tcttcctggg agtgaggagg ctggtgtgag tttcgatctt cctgcccagg cagacacctt
     3121 acacagtgca aacaagggtc gtgtcaaagt gagaggaaag aggagaccac agacccgtgc
     3181 tgctcggcgg ctggctgccc aggagtccag cgaggctgag gacgtgatca ttgatagagg
     3241 acctgttaca cagttgagca gtagtcctgt cttaccaaac ggccatcaac ctcttctgca
     3301 gcctaggatg gccagtggag agaccagctc tgaaaaagcc atggccgtac cttgggaagg
     3361 tggtcctgtt ttatctgcag tggacagaag cttctttgta aagtctctgc ctcagactgg
     3421 aaatgaggcc cacctgtttg attctgggga cattttcccc aagagcacag gatcacagtc
     3481 catggaggga gcaagtgtca aggcagggga gaccccagcc cactcgtcag cagggcggaa
     3541 ggagaagagc ctggtatttc ctgatcttag tgaggccagc ggtgtcgatg accttttcca
     3601 gtctgccaag ccaagaccaa caaagaaaag aaaccctttc cccctccttg aagatgagga
     3661 ggacctcttt gcagatcaga aaggcaaaaa gaatcagtgg aaatctgaca gccatcagga
     3721 cgttgtgtca aaaactcaag acatctttga ggatgatata tttgctacgg aagcaattaa
     3781 gaagcctttt ccaaaaaaaa gagagaagga gagaactttg gaacccaact tatttgatga
     3841 taatattgat atcttcgctg acttgactgt gaaacccaaa gaaaagccca aaaagaaagt
     3901 cacagccaag tccatgtttg acgatgatac agatgatatt ttctcctctg gcctccaggc
     3961 taaagcatct aaacccaaaa gccaatctgc tgaggcagca tctgaattaa ggtctgagaa
     4021 ccaagtgtcc aacatttttg atgaccctct gaatgccttt ggaagccagt agagcatgca
     4081 ggaccttcgc agttcaccct ccattctgtc tttcatttag tgatgctgtt tcctacaccg
     4141 tcttcactgg attacaggca aatactgcaa caatcactac ttttacccaa tgtagctaat
     4201 atttttctgc attgatttta attatgctta aaattacaaa taaaaaataa acgctt
//
