LOCUS       NM_001270417            2385 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus WW domain containing adaptor with coiled-coil
            (Wac), mRNA.
ACCESSION   NM_001270417 XM_003751718 XM_003753006
VERSION     NM_001270417.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2385)
  AUTHORS   McKnight NC, Jefferies HB, Alemu EA, Saunders RE, Howell M,
            Johansen T and Tooze SA.
  TITLE     Genome-wide siRNA screen reveals amino acid starvation-induced
            autophagy requires SCOC and WAC
  JOURNAL   EMBO J 31 (8), 1931-1946 (2012)
   PUBMED   22354037
REFERENCE   2  (bases 1 to 2385)
  AUTHORS   Totsukawa G, Kaneko Y, Uchiyama K, Toh H, Tamura K and Kondo H.
  TITLE     VCIP135 deubiquitinase and its binding protein, WAC, in
            p97ATPase-mediated membrane fusion
  JOURNAL   EMBO J 30 (17), 3581-3593 (2011)
   PUBMED   21811234
  REMARK    GeneRIF: WAC is hence thought to function in p97/p47-mediated Golgi
            membrane fusion by activating the deubiquitinating function of
            VCIP135.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2385)
  AUTHORS   Zhang F and Yu X.
  TITLE     WAC, a functional partner of RNF20/40, regulates histone H2B
            ubiquitination and gene transcription
  JOURNAL   Mol Cell 41 (4), 384-397 (2011)
   PUBMED   21329877
REFERENCE   4  (bases 1 to 2385)
  AUTHORS   Xu GM and Arnaout MA.
  TITLE     WAC, a novel WW domain-containing adapter with a coiled-coil
            region, is colocalized with splicing factor SC35
  JOURNAL   Genomics 79 (1), 87-94 (2002)
   PUBMED   11827461
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB574169.1.
            
            On or before Jul 6, 2012 this sequence version replaced
            XM_003751718.1, XM_003753006.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: AB574169.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMD00132261, SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2385
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.1"
     gene            1..2385
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /note="WW domain containing adaptor with coiled-coil"
                     /db_xref="GeneID:307029"
                     /db_xref="RGD:1562407"
     exon            1..249
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
     CDS             209..2149
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /codon_start=1
                     /product="WW domain-containing adapter protein with
                     coiled-coil"
                     /protein_id="NP_001257346.1"
                     /db_xref="GeneID:307029"
                     /db_xref="RGD:1562407"
                     /translation="MVMYARKQQRLSDGCHDRRGDSQPFQTLKYSSKSHPSSGDHRHE
                     KMRDAADPSPPNKMLRRSNSPENKYSDNTGHNKAKNVHTQRVREREGGTSYSPQENSH
                     NHSALHSSNSHSSNPSNNPSKASDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKP
                     KEWLEREQRQKEANKLAVNSFPKDRDYRREVMQAAATSGFTSGMEDKHSSDASSLLPQ
                     NILSQTSRHNDKDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQP
                     KKSFDANGASTLSKLPTPTASLPAQKTERKESAPGDKSVSHSCTTPSTSSASGLNPTS
                     APPTSASAVPVSPVPQSTIPPLLQDPNLFRQLLPALQATLQLNNSNVDISKINEVLTA
                     AVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSY
                     VSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKPGPVSHSATQQPVTADKQQGHD
                     PVSPRSLQRLSSQRSPSPGPNHTCSSNASTAAVVPQNASARPACSLTPTLAAHFNDNL
                     IKHVQGWPADHAEKQASRLREEAHNMGSVHMSEICTELKNLRSLVRVCEIQATLREQR
                     ILFLRQQIKELEKLKNQNSFMV"
     exon            250..286
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
     exon            287..482
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
     exon            483..589
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
     exon            590..705
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
     exon            706..818
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
     exon            819..1127
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1373
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
     exon            1374..1496
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
     exon            1497..1645
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1764
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..1951
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
     exon            1952..2079
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
     exon            2080..2385
                     /gene="Wac"
                     /gene_synonym="RGD1562407"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctgtcccg gctgacccta agcggtggtg acggagggag atgaccgggg accgccggcg
       61 ccagtaacgg ggaggtgccg cgagccgccg agggtgcgcc gagtcctggt gccggggctg
      121 cccgccgccc gcccgccgcc cgcgcgcgcg cccgcccgcc tcgcggccgc tctccccctc
      181 cccgacacac acacacagcc gggcattgat ggtaatgtat gcgaggaaac agcagagact
      241 cagtgatggc tgtcacgacc ggagggggga ctctcagcct ttccagacac ttaagtattc
      301 gtcaaagagt caccccagca gtggtgatca cagacatgaa aagatgcgag acgccgcaga
      361 tccttcacca ccaaacaaaa tgttgcggag atctaatagt cctgaaaaca aatacagtga
      421 caacacaggt cacaataagg ccaaaaatgt gcatactcaa agagttagag aaagggaagg
      481 tgggaccagt tactctccac aagaaaactc acacaaccac agtgctcttc atagttcaaa
      541 ttcacattct tctaatccaa gcaataatcc gagcaaagct tctgatgcac cttatgattc
      601 tgcagatgat tggtctgagc acattagctc atctggaaaa aaatactact acaattgtcg
      661 cacagaagtt tcacagtggg agaaaccaaa agagtggctt gaaagagaac agagacaaaa
      721 agaagcaaat aagttggcag ttaatagttt cccaaaagac agggattaca gaagagaggt
      781 gatgcaagca gcagccacta gtgggttcac cagtggaatg gaagacaagc attccagcga
      841 tgccagtagt ttgctcccac agaatatttt gtctcaaaca agcagacaca atgacaaaga
      901 ctacagactg ccaagagcag agactcacag tagctctacg ccagtacagc accccatcaa
      961 accagtggtt catccaaccg ctaccccaag cactgttcct tctagtccat ttacgcttca
     1021 gtctgatcac cagccaaaga aatcatttga tgctaatgga gcatctactt tatcaaaact
     1081 gcctacaccc acagcttctc tccctgcaca gaaaacagag agaaaagaat ctgctccagg
     1141 agacaagtca gtatcacact cttgcacaac tccttccaca tcttcagcct ctggcctgaa
     1201 ccctacatct gcgcccccaa catctgcttc agccgtacct gtttctcccg tcccacagtc
     1261 gacaatacct ccattacttc aggacccaaa cctttttaga cagttgcttc ctgctttgca
     1321 agccacgcta cagcttaata attctaatgt ggacatatcc aaaataaatg aagttcttac
     1381 agcagctgta acacaagctt ccctgcagtc tatcatccac aagtttctta ctgctggacc
     1441 atctgctttc aacatcacct ctctgatttc tcaagctgcc cagctttcta cacaagccca
     1501 gccatctaat cagtctccaa tgtctctaac gtctgatgct tcatccccaa gatcctatgt
     1561 gtctccaaga ataagcacac ctcagactaa cacagtcccc attaaacctt tgattagtac
     1621 tccgcctgtc tcatcacagc caaaggttag tactccagta gttaagccag gaccagtgtc
     1681 acattcggct acacagcagc ccgtgactgc tgacaagcag cagggccatg atcctgtctc
     1741 tccacgaagt cttcagcgct taagtagcca gagaagtcca tcacctggtc caaatcatac
     1801 ttgtagtagt aatgcatcaa ctgcagctgt tgtaccacag aacgcatctg ctaggcctgc
     1861 gtgctcatta acacctactc tagcagcaca cttcaatgat aatctcataa aacatgttca
     1921 agggtggcct gcagaccatg cagagaaaca ggcatcaaga ttgcgtgaag aagcccataa
     1981 tatgggaagt gttcatatgt cagaaatatg tactgagtta aaaaatttga gatcattagt
     2041 tcgagtatgt gaaattcaag caactttgcg agagcagagg atactctttt tgagacaaca
     2101 aattaaggaa ctcgaaaagc taaaaaatca gaattccttc atggtttgaa gatgtgaata
     2161 attgcacatg atctcataga ggaactgtaa atctgttgcc cagtcataac attttgagct
     2221 gcatttcagt agaccatgga ccgttaagct gggcaaatga aatgacaagg ggacggggtc
     2281 tgtgagagtc aattcagggg aaagatacaa gattgatttg taaaaccctt gaaatgtaga
     2341 tttcttgtag atgtatcttc acgttgtaaa tatgttttgt agagt
//
