LOCUS       NM_001109312            3364 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus von Willebrand factor C domain containing 2
            (Vwc2), mRNA.
ACCESSION   NM_001109312 XM_001055520 XM_576652
VERSION     NM_001109312.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3364)
  AUTHORS   Schwenk J, Harmel N, Brechet A, Zolles G, Berkefeld H, Muller CS,
            Bildl W, Baehrens D, Huber B, Kulik A, Klocker N, Schulte U and
            Fakler B.
  TITLE     High-resolution proteomics unravel architecture and molecular
            diversity of native AMPA receptor complexes
  JOURNAL   Neuron 74 (4), 621-633 (2012)
   PUBMED   22632720
REFERENCE   2  (bases 1 to 3364)
  AUTHORS   Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C,
            Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D,
            Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N,
            Kimata K, Hayashizaki Y and Sekiguchi K.
  TITLE     Transcriptome-based systematic identification of extracellular
            matrix proteins
  JOURNAL   Proc Natl Acad Sci U S A 105 (35), 12849-12854 (2008)
   PUBMED   18757743
REFERENCE   3  (bases 1 to 3364)
  AUTHORS   Koike N, Kassai Y, Kouta Y, Miwa H, Konishi M and Itoh N.
  TITLE     Brorin, a novel secreted bone morphogenetic protein antagonist,
            promotes neurogenesis in mouse neural precursor cells
  JOURNAL   J Biol Chem 282 (21), 15843-15850 (2007)
   PUBMED   17400546
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474055.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001055520.1, XM_576652.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760396,
                              SAMN12840105 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3364
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..3364
                     /gene="Vwc2"
                     /note="von Willebrand factor C domain containing 2"
                     /db_xref="GeneID:501231"
                     /db_xref="RGD:1589624"
     exon            1..311
                     /gene="Vwc2"
                     /inference="alignment:Splign:2.1.0"
     exon            312..1107
                     /gene="Vwc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             415..1389
                     /gene="Vwc2"
                     /note="brorin"
                     /codon_start=1
                     /product="brorin precursor"
                     /protein_id="NP_001102782.1"
                     /db_xref="GeneID:501231"
                     /db_xref="RGD:1589624"
                     /translation="MPSSSAMAVGALSSSLLVTCCLMVALCSPSIPLEKLAQAPEQPG
                     QEKREHASRDSPGRVSELGRASRDEGSSARDWKSKGSRALSGREAWSKQKQAWAAQSG
                     SAKAADWQVRPRGDTPQGEPPAAAQEAISLELMPTPELPEEYAYPDYRGKGCVDESGF
                     VYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCE
                     FRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGP
                     NCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECRQM"
     exon            1108..1237
                     /gene="Vwc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..3364
                     /gene="Vwc2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgagactggg ctctgacggc tccctagggc gcgcttcttg atggagattc agggacgaga
       61 cccggggatg agaggtggaa ggcagcgcgg gcactgacag gactccggga ggaggctacc
      121 agccatcagc agccagatga acaggctagg tcaaatgctc taaccgggtg catgcgccag
      181 gcggagcgcg ctggtcggac tgttctctgc ggtccgccct gcgctggtcc ccggtcatca
      241 ccagaatgga cactggagcc ccagggccgc gcccgctaga gcccggcgtc cctcctgcgt
      301 cctgagctca tggacaacga ctcccggctg gcagcggcgc gccccagggc tgtgaatgcg
      361 acttgctcaa cgtccgcgct ccccgcccgc ccgcccgccg ggacgtggta ggggatgcct
      421 agctcctctg cgatggcagt tggcgcgctc tccagttccc tcttggtcac ctgctgcctg
      481 atggtggctc tgtgcagtcc gagcatcccg ctggagaagc tggcccaagc tccagagcaa
      541 cccggccagg aaaagcgcga gcacgcgtct cgggacagcc cgggaagggt gagcgagctc
      601 gggcgcgcct ctagggacga gggcagcagt gcccgggact ggaagagcaa gggcagccgc
      661 gcgctctcgg gccgggaggc gtggagcaag cagaagcagg cctgggctgc ccagagcggg
      721 agcgccaagg ccgcggactg gcaggtccgg cctcgcgggg ataccccaca gggggagccc
      781 ccggccgccg cccaggaagc gatcagtctg gaactcatgc ccacaccgga gctgcctgag
      841 gaatacgcct atcccgacta ccgcgggaag ggctgcgtgg acgagagtgg cttcgtgtat
      901 gcgattgggg agaagttcgc cccaggtccc tcagcctgcc catgtctgtg tacggaggag
      961 gggccccttt gcgcccagcc agagtgcccg cggcttcacc cgcgctgcat ccacgttgac
     1021 accagtcagt gctgtccgca gtgcaaagag aggaagaact actgcgagtt ccggggcaag
     1081 acctaccaga ctttggagga gttcgtggtg tctccatgtg aacggtgtcg ctgtgaagcc
     1141 aatggtgaag tgctgtgcac agtgtcggcg tgtccccaga cggaatgtgt ggaccccgtg
     1201 tatgagcctg atcagtgctg cccgatctgc aaaaacggtc caaactgctt tgcagaaacc
     1261 gctgtcatcc cagctggtcg agaggtgaag actgacgaat gcaccatatg tcattgtact
     1321 tatgaggagg gcacgtggag aattgaacgg caagccatgt gcacgagaca tgaatgcagg
     1381 caaatgtaga cttcgtgata cagaaactct catgtttttc tagaatattt tactaatgtg
     1441 acattctaga tgactctgag aaatatcaat caaaaacaga agactttgga taaggagtca
     1501 aggaaaatgg ttggtacttt tgtttttctt ggtaacaatt acagcaagag acagaaatgg
     1561 atgtatttca aaacatcaat aagaactttg ggcatactcc ctctctaaat aaatgtgcta
     1621 ttttcacagt aagtacacta aagttcacta ttatatatta aatgtgtttc tataatccct
     1681 ctattagagt cttctatatt aaaaatgctg ttgtcaaccg tcctcactgt gtaccggtat
     1741 atctttgtta gccttcactg caccacaaga gggtgctagt gggtccaggg atctcttaca
     1801 cctgcacacg gaatgctcta ctccattagg aactacagga aataatgact gttttatatc
     1861 aaaaccctgt tcaaatgcta cttaactaat gctatgtatc taatgcttaa aacgcaatct
     1921 aatttacaca aacaggctta ttttaataac ccacttcttt ttttagttca ttcttagtca
     1981 tttctaaatt gtagctataa agatggctag catagcctgt ttcagttctc atagtagccc
     2041 acaaataaac acttatgtgc atttcatgtt catccaatgg tacatgttct tctaagcatg
     2101 acattaattc attccctgag caagaggaag gttgggatat atgtgttatt aaaaaaaaat
     2161 ggaggaaagg gagtctttgg gttctgcaga gaaaagttat gaaaagtcaa attcctgaac
     2221 aggtttatgc ttgaaatata aaatatacta gacatctcag gactcagcac aggttcctgt
     2281 actgctagtt gaggtagcta tctgccctct gtaacagaca gagtgagaga ataaatcaat
     2341 tttgccccaa gaacggtgta cagaagctat tctttgtcca attatgttta agcatttgaa
     2401 aatgaaggct actaagtctc tcctgcagtc atatatcacc caaattttct tcctttgaat
     2461 ataaaatgat aaaactgtca ttaagtgttg ctgactggag cacagtgata gggaacagct
     2521 cccttgttgt gagtgacatc aacagttggt gcaggagtca gagaggcatc agggtcctaa
     2581 tctgtgtaaa aacactaaac atcaagaaca tttccctcca tttacacttt ctgaatttta
     2641 aaatgaggac ctatcgcaca acagatcttg tgaagacaag aaggaaatga ggactggttt
     2701 gttttcccca tgtgctctgc atctttttct gtagcataac aggactataa aattacactg
     2761 taagatatta tatataaagc aaattagagg ctagaaaatg gagatttcta agaaagtaca
     2821 atttatatcc ccaaaccctg tcagtatata agaatttcag taatttacta tttaatgttt
     2881 tctcatcatt gaaaagttaa tcattatata ctttaataca aaaattacca agatatttgc
     2941 atatgcttat attttatctt gatttttgaa gactattttg ggttaggtaa agtagcaaat
     3001 aaatcaattt catgaaaata ctcaggggta ttattggcca gttactctca ggtacctgtt
     3061 ttgagctttc caaaacttaa gtgttagtat gaacgaccat taggcatcat ctgtctttcc
     3121 gtttctcaac agtaggttta ctttaagaca aaggtcatct aaggttacca tcctgccaac
     3181 aaatgactta acctcctaca atacatgggt taaagagccg gttgtaatta catacaactt
     3241 gcctcttctt tccacatgag acatgatgaa ttacaactgc agtgtatgag gcccagtttt
     3301 cttattttcc ttggcaacag aattcccaca gaatggaaaa tgggctctca gattacttca
     3361 gtgg
//
