LOCUS       NM_001393948            3944 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus von Willebrand factor A domain containing 5A
            (Vwa5a), transcript variant 1, mRNA.
ACCESSION   NM_001393948 XM_039081324
VERSION     NM_001393948.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3944)
  AUTHORS   Monaco,C., Negrini,M., Sozzi,G., Veronese,M.L., Vorechovsky,I.,
            Godwin,A.K. and Croce,C.M.
  TITLE     Molecular cloning and characterization of LOH11CR2A, a new gene
            within a refined minimal region of LOH at 11q23
  JOURNAL   Genomics 46 (2), 217-222 (1997)
   PUBMED   9417908
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Mar 23, 2021 this sequence version replaced XM_039081324.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.31238.1,
                                           SRR26643297.27945.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-99                JAXUCZ010000008.1  47712386-47712484
            100-157             JAXUCZ010000008.1  47716045-47716102
            158-360             JAXUCZ010000008.1  47716218-47716420
            361-583             JAXUCZ010000008.1  47716694-47716916
            584-759             JAXUCZ010000008.1  47717035-47717210
            760-874             JAXUCZ010000008.1  47717485-47717599
            875-1044            JAXUCZ010000008.1  47722715-47722884
            1045-1133           JAXUCZ010000008.1  47723547-47723635
            1134-1278           JAXUCZ010000008.1  47723804-47723948
            1279-1358           JAXUCZ010000008.1  47724547-47724626
            1359-1473           JAXUCZ010000008.1  47727921-47728035
            1474-1638           JAXUCZ010000008.1  47728753-47728917
            1639-1739           JAXUCZ010000008.1  47729199-47729299
            1740-1999           JAXUCZ010000008.1  47729598-47729857
            2000-2068           JAXUCZ010000008.1  47731343-47731411
            2069-2167           JAXUCZ010000008.1  47731505-47731603
            2168-2298           JAXUCZ010000008.1  47732063-47732193
            2299-2425           JAXUCZ010000008.1  47734187-47734313
            2426-3944           JAXUCZ010000008.1  47734781-47736299
FEATURES             Location/Qualifiers
     source          1..3944
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q22"
     gene            1..3944
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /note="von Willebrand factor A domain containing 5A"
                     /db_xref="GeneID:301097"
                     /db_xref="RGD:735145"
     exon            1..99
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            100..157
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             115..2505
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /note="mast cell surface antigen 1; loss of heterozygosity
                     11 chromosomal region 2 gene A protein homolog; loss of
                     heterozygosity, 11, chromosomal region 2, gene A homolog;
                     von Willebrand factor A domain-containing protein 5A-like"
                     /codon_start=1
                     /product="von Willebrand factor A domain-containing
                     protein 5A"
                     /protein_id="NP_001380877.1"
                     /db_xref="GeneID:301097"
                     /db_xref="RGD:735145"
                     /translation="MEHHWGLITGNKEKVPLKSISVTLSINDFVAAVAATLHYENEEK
                     VPIEAMFVFPMDEDSAVYSFEALVDGKKIVAELQDKTKAHSKYEEALSQGHQAYLLEE
                     DDYSRDVFSCNVGNLQPGTKVAVTLRYVQELPLESDGALRYLLPAVLNPRYQLSEQSA
                     SSCLNVQKPIVPLEALPYTLSMVATITSQHGIERVQSNCSLSPIQYLTDDKTSAQVSL
                     TEGHKFDRDVELLIYYREVHSPSVAVEKGMQDKKRDSLMGAPCAMVSFYPDIPEVNAS
                     KVCGEFVFLMDRSGSMQTPMRTEENSQLRIEAAKETLLLLLKSLPMGCYFNIYGFGSS
                     YEQFFPESVKYTQETIEEAVERVKRLDADLGGTEILTPLRNIYKTSSIPGHPLQLFVF
                     TDGEVSDTYSVIREVKLNSKKHRCFSFGIGQGASTSLIKNIARVSGGTAEFITGKDRM
                     QAKALGSLKLALQCALDDISLSWELPPGLSVNMLSPEQPTIFRGQRLIIYAQLTGPMP
                     QAESRGAVCLKHTLQGKSLENKVAFSLQPKENANFTIHRLAAKFLIQTKDLGSHEVSK
                     EEKKDVMNISLQSGVLSSFTAFVAINKELNKPVQGPLAHRVIPRPMIATSTSMFMRSC
                     SRLTGPFKNSRLKRRLCAADYVPYGHESTVYSSMPSPAPIENQGVADSSNEKSNSQNE
                     HKAFGENVVLQLIFLQNANGSWKLDENLTKILGTTLEDTKAANPSQHGDPSAWATILA
                     VLWLHANGQDLKCEWELLERKAVAWLHDHAGSSIPMLVQAANSLLKLSVNPAVFDV"
     exon            158..360
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            361..583
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            584..759
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            760..874
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            875..1044
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1133
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1134..1278
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1279..1358
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1473
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1474..1638
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1639..1739
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1740..1999
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2000..2068
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2069..2167
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2168..2298
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2299..2425
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2426..3944
                     /gene="Vwa5a"
                     /gene_synonym="Loh11cr2a; masa-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctttcactt tggtttccga agctgctgag acttcaggag gctggtgatt gctgaacttt
       61 gctctctctg ggaagagtcc tgcccgatct ctctaaagga aacaggcagt taccatggag
      121 catcactggg gcctaatcac tggcaacaag gagaaagtac cactgaagag catctcagtc
      181 accttgtcca tcaatgactt tgtggctgct gtggctgcaa ccctacatta tgagaatgag
      241 gagaaagtcc caatagaggc aatgtttgtg tttcctatgg atgaagactc tgctgtctac
      301 agctttgaag ccttggtgga tgggaagaaa atcgtggcag agttgcagga taagacgaag
      361 gcgcacagca agtatgagga ggcactctcc cagggccacc aagcatactt attggaagag
      421 gatgattatt ccagggatgt cttttcttgc aatgtgggga acctgcagcc tggaactaag
      481 gttgcagtta ccttgaggta tgtgcaggaa ctgccattgg aatcagatgg ggccctgcgc
      541 tacctgctcc cagcagtctt gaatccaaga tatcagcttt ctgaacagtc agcgagcagt
      601 tgcttgaatg tacagaagcc cattgtccct ttggaggccc tgccttacac actcagcatg
      661 gttgccacca tcacttccca gcatggtatt gagagggtcc aatccaactg ctccttgagc
      721 cctattcagt accttacaga tgacaagact tctgctcagg tttccttgac tgaagggcat
      781 aagtttgacc gggatgtgga actcctgatt tactaccgtg aagtgcacag ccccagtgta
      841 gctgtggaga agggaatgca ggacaagaag cgagatagtt tgatgggagc tccttgtgca
      901 atggtgagct tctacccaga catcccagaa gtgaacgcct caaaggtctg tggagaattt
      961 gtgtttctaa tggaccgctc aggaagtatg caaaccccca tgagaacaga ggaaaattct
     1021 cagctacgca tagaggctgc caaggaaact ctgctgttgt tgctgaagag tttgcctatg
     1081 ggttgttatt ttaacatcta tggatttgga tcttcctatg aacaattctt cccggagagt
     1141 gtgaagtaca ctcaggaaac aattgaggaa gcagtggaac gagtgaagcg tttagatgcc
     1201 gatttagggg gtactgaaat cttgacaccc ctccgcaaca tttacaagac atcctccatt
     1261 cctggacatc ccctacagct ctttgtcttc acagacggag aagtgagtga cacatatagt
     1321 gtcatcagag aagttaagtt aaacagcaag aaacacagat gtttctcatt tggtattgga
     1381 caaggagcct ccaccagctt aatcaaaaac atcgcccggg tatcaggggg cactgcagag
     1441 tttatcacag gcaaggacag gatgcaggct aaggctcttg ggtctctcaa gcttgcgcta
     1501 cagtgtgcat tggatgatat ctccctgagt tgggaattgc ctcctggtct gtctgttaac
     1561 atgctctctc cagagcagcc taccatcttt aggggtcaga ggttaatcat ctatgcccaa
     1621 ctgactgggc ctatgcctca agcggagagc agaggagcag tgtgcctcaa gcacaccctc
     1681 cagggcaaga gtctggaaaa caaggtggca ttttccctac aacccaagga aaatgccaat
     1741 tttaccattc atcggttggc ggcaaagttc ttgattcaga ccaaggattt gggatcccat
     1801 gaagtctcaa aagaagagaa aaaggatgtg atgaacatca gccttcagtc tggagttctc
     1861 agctccttca cagcctttgt tgccataaac aaagagctta acaagccagt gcagggccct
     1921 ctggcccaca gagtcattcc taggccaatg atagctacat ctacatctat gtttatgagg
     1981 tcatgcagtc gtctcacagg tccctttaaa aactcacgcc taaaacgtag attatgtgca
     2041 gcagactatg ttccatatgg acatgaaagc actgtgtatt ctagcatgcc aagtccagca
     2101 cccatagaaa atcagggagt ggcagattct tcgaacgaga aaagcaactc gcaaaatgaa
     2161 cacaaagcat ttggggagaa tgttgtgttg cagctgattt ttctgcaaaa tgcaaatggc
     2221 tcctggaagc tggatgaaaa tctgaccaag atcctgggca ctacattgga agacaccaag
     2281 gctgccaacc cttctcagca tggggacccc tcagcctggg ccacaatcct ggctgtgctc
     2341 tggctccatg ccaatggcca ggacttaaag tgtgagtggg agcttctgga acggaaggct
     2401 gtggcctggc ttcatgatca tgcaggctct tctatcccca tgctcgttca agctgccaat
     2461 agtctcctga aattatctgt gaatcctgct gtctttgatg tctaaaggtg tcacccatga
     2521 aaggagagcc tttcctggct acccctgtgt ccctcacttc tcctcagctg agatagcttt
     2581 ggggttctat ccttcccttt tctttcttgt cataacaagg acatactgac agccttggtg
     2641 atcattccta gtacctttgt atctgatttt ctacccctat catttcttct gtgagaagtt
     2701 agcatggtct cccaacatgt tttcttcctt gagactttta ttcatgtgca gaatgacaca
     2761 tgaagttttc caagccaatt atgatataac ggttggcata agatctagag taagcatgca
     2821 gtgttgacca tgggtaatgc ttgagttaat aacctgcatt actgttattg cctctctatg
     2881 cagagccatg tagtatggtc aacaaatggc tttaaactcg tgggatcggc ctaccagtta
     2941 gcacagccac gatggatgct cctcagttga ggtaggacct gtaggattac atgttctgag
     3001 gacctcatgc tgtgaatgga tttttttgct ctgcctgttg ccttcacatt cttcataaac
     3061 taaggattgt ttgaaaagtc taagcaggat tccagcacca ccctgggcag tgtcattggc
     3121 actaaacgat aataatgttt gatatctttc aagtactggt ggtggagcag attaatgatt
     3181 caattactac cctaggaaac aacttagaga tgaagatttt cagcagtgac cactaccctt
     3241 agaatcttta tttggaaaaa taaagttttg tgaacctatg ttaagttttt ttttttccta
     3301 ttgacacggt tttaaaaaat cctagcgaac agttcgaagt tctgagaggc acatttaagc
     3361 tagggatggt ttatggtcag aggacaagaa caatggcaac aagggctaac atgaggatca
     3421 ctgaggctgg actggtgatg attgattttt tatgtctatt tttgccttct gtttcctgat
     3481 acgattcaat aagaattgct gatgagtaga tatgcattct taggatttta attgatatga
     3541 ccgactttta tataaaagtt tagatttcag attcattaaa gatctgtctg agcttactct
     3601 tcaagataaa tgaaataatc agtccttcct ttgtaagtgg aaatttcagc ctgccagtaa
     3661 gaagagctgg gcgaaaaaaa attatcttgt ttacttacac attttaaatc tataacaagt
     3721 tgcttaatta tgaatgtaca tgggttcttg gtaataattt ttcttcttta cctatattac
     3781 ataatgttat ttcttctaaa gatattgtat aacatcctgt tttttttttt tcgtagtcat
     3841 tcgctagaag gaaaagagaa tgtaatccaa ttgtaatttt atactgctta aaagattttg
     3901 ctggaatata taagagatgg gaaaaaataa aatcattgaa cctc
//
