LOCUS       XM_003749146            5344 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus von Willebrand factor A domain
            containing 2 (Vwa2), mRNA.
ACCESSION   XM_003749146
VERSION     XM_003749146.5
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_003749146.6.
            
            On Jan 21, 2021 this sequence version replaced XM_003749146.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5344
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5344
                     /gene="Vwa2"
                     /note="von Willebrand factor A domain containing 2;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 EST, 4 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     3 samples with support for all annotated introns"
                     /db_xref="GeneID:307988"
                     /db_xref="RGD:1562000"
     CDS             1602..3980
                     /gene="Vwa2"
                     /codon_start=1
                     /product="von Willebrand factor A domain-containing
                     protein 2"
                     /protein_id="XP_003749194.3"
                     /db_xref="GeneID:307988"
                     /db_xref="RGD:1562000"
                     /translation="MRRRTRSNNMPPYLFLPAIYTLLFSRVSLSSSLQEVHVSRETTG
                     KIAVASKLIWCSAAVDILFLLDGSHSIGKGSFERSKRFATALCDALDISPGRVRVGAL
                     QFGSTPHLEFPLDAFSTRQEVKEIIKKLVFKGGRTETGLALKHLLRGLPGGRNGSVPQ
                     ILIIITDGKSQGHVALPAKQLKERGIVVFAVGVRFPRWDELLTLASEPKEQHVLLAEQ
                     VEDATNGLLSTLSSSLLCTTADPDCRVEAYPCERRTLETMRELASNALCWRGSRQADT
                     VLAVPCPFYSWKRVFQTHPANCYRTICPGPCDSQPCQNGGTCIPEGVDRYHCLCPLAF
                     GGEVNCAPKLSLECRIDVLFLLDSSAGTTPEGFRQAKAFVKRFVQAVLSEDSRARVGV
                     ASYSRDLMVAVPVGEYQHVPDLVRILDSIPFSGGPTLTGSALLQVTEHGFGSASRTGQ
                     DRPRRVVVLLTESHAQDEVAGPADHARARELLLLGMGNELMRAELERITGSRKHVIIH
                     TDPRDMFSQIPELQRRLCSQPRPGCQAQSLDLVFLLDASASVGGENFAQMQSFIRKCT
                     LRFDVNPDVTQVGLVVYGNQVQTAFGLDTHPTRASVLRAMSQAPYLGGVGSAGTALLH
                     IEDKVMTVQRGARPGVPKAVVMLTGGSGAEDAAVPAQKLRDNGISVLVMSVGAVLKEA
                     VRRLAGPRDYLIHVAAYTDLRYHQDTLIEWLCREAKRPVSLCKPSPCMNEGTCILKNG
                     SYRCECWGGWEGPHCENRVLRGDAPMAHSFRREPTGRQQPTPSQQAPKHVGV"
ORIGIN      
        1 gtttgcaaca tcaaagctgc caggaggggt tggggattta gctcagtggt agagcgcttg
       61 cctaggaagc acaaggccct gggttcggtc cccagctcct gaaaaaaaaa aagaacaaaa
      121 aaaaaaaaaa aaaaaaaaag ctgccaggag tgcatttccc tgaaagctct cttgacagaa
      181 gttggaaacc aactgagaac tacagaatga aatgcaacag attttaaaat gaatgtgtaa
      241 aagtacaaat tgggtattta cccgacagat tgacatttac agggatactg gggaaaagtc
      301 agaaaatagg gaacagatca gtttcccgga agatagttat gttaaaaaca aacaaaaaac
      361 ccagaccttg gtcaaggaga tagcctagcg ggcaaaggca cttgccccgc agcttgccaa
      421 tgtgatttca atattcaaaa atcttgtggt agaagaaaaa aggaacaaaa ccggtgcaca
      481 cacctgcacc tacaaacaca agtgtgaaaa atgtaattct tgtatgttac ttgtagtcta
      541 gggaatttat tactttgttt ccagatgtag ttgggcagcc ccaggaagac atttgatcgc
      601 ggtgttacac ttgaggcctt agcattgagc agtagcaacg ggtgaacagg tagagcggtg
      661 gtggcccaaa ccacagatgt tcaacacagg tgaatcaagt ttcaacggaa tgaaccaagg
      721 ttttgtagga ggaaatgaaa gctttttcct agtgctccgt agctgagtac ctgtggcttt
      781 tctatttgtt ttctcttgtt ttctattttt taaacttttc caatgagcac ataatatgta
      841 gtttttatta agtatgaaaa agagagttta tgtgcacaga gtacctgcca gaaagcacag
      901 ttttgttttg tgacctggcg ctctctaagt caaaaggaga atgctgccca ataatcaccc
      961 aactgcaaga actaacaggc tggttggcaa aaagcagaaa ccgtgacaag tcgaaacgag
     1021 gccaaagtca acatttcctc aggtgtggaa tcgataaaac ctgcggaata gccaacgcgc
     1081 tctgtgacca cagtgcaccg tttgtggcgg cccgctctct cggaagtgtt tacagtgctg
     1141 cggttgcggg tcgcccagta gaaagagagt cgaggcgggc gcggttcccc ggagcagcgg
     1201 ttgcaccgcc ctcacgctga acgtagggat cctcacaggc tgcattcgag cggtctggcc
     1261 cgcctccgct gggagagacc aacaggtgcc ccacgtggct gcgccccggg aacagagccc
     1321 agcctgcgcc gctgcagagc agctgcgcgc tccgcgggtg ggaacccctc accttccaac
     1381 aggcggggca gggcgaggcg cacccctgcc agtaagcggg caagcgatag tgcggagccc
     1441 cagccccgcg cccgcgcccg cgcccgcgcc cgtgcccgtg cccgcgcccc tacctgccga
     1501 gtcaagagga gcgccgcggg ctttgttcgc tttgtcctca cgcacctaag ctaccctccc
     1561 ggaaggatac cctcccggaa ggataccatc ccggagaacg catgcggcgc cgcaccaggt
     1621 ctaacaacat gcctccatat ctgtttctac cagccatcta cactctcctg ttctccagag
     1681 tttccctgtc cagctctctt caggaagtgc atgtgagccg ggagaccacg ggaaagatcg
     1741 cagtggccag caaattgata tggtgctcag ccgcggtcga catcctgttc ctgttagatg
     1801 gctctcacag cattgggaaa gggagcttcg agaggtccaa gcgctttgcc actgctctct
     1861 gcgatgccct ggacatcagt cctggcaggg tcagagtggg cgccttgcag tttggttcca
     1921 ctcctcatct ggaattccct ttggatgcct tttcaacccg acaggaagtg aaggagatca
     1981 tcaagaagtt ggtttttaaa ggtgggcgca cagagacagg cctagccctg aaacacctgc
     2041 tcagagggct ccccggagga agaaatggct ctgtgcccca gatcctcatc atcatcacag
     2101 acggcaagtc ccaggggcac gtggctctgc cggctaagca gctgaaagaa aggggtatcg
     2161 ttgtgtttgc agtaggggtc cgttttccca ggtgggatga gctgctgacg ctggccagcg
     2221 agccgaagga gcagcatgtg ctgttggccg agcaagtgga ggatgccacc aatggcctcc
     2281 tcagcaccct cagcagctcc ttgctctgca ccactgctga tccagactgc agggtggaag
     2341 cttacccgtg tgagcggaga acgctggaga ccatgagaga gctcgccagc aatgccttgt
     2401 gctggagagg atcaaggcag gcggacactg tgctggctgt gccctgtccc ttctacagct
     2461 ggaagagagt gttccagact caccccgcca attgctacag aaccatctgt ccaggcccct
     2521 gtgactccca gccatgccaa aatggaggca cgtgcattcc agaaggtgtg gacaggtacc
     2581 actgtctctg cccactggca ttcggagggg aagtcaactg tgccccgaag ctgagcctgg
     2641 aatgcaggat cgatgtcctc ttcctgctgg acagttctgc aggcaccact ccggagggct
     2701 tccgtcaggc caaggccttt gtgaagcgct ttgtgcaggc cgtgctgagt gaggactccc
     2761 gagcccgtgt tggggtagcc agttacagca gggatctaat ggtggcggtg cctgttgggg
     2821 agtaccagca tgtgccagac ctggtcagga tccttgacag cattcccttc agcggtggcc
     2881 caactctgac cgggagtgcc ttgctgcagg tgacagagca tggctttggg agtgccagcc
     2941 ggacaggaca ggacaggcca cgcagagtag tggttctgct cactgaatca cacgcccaag
     3001 atgaggtggc tgggccagca gatcatgcga gggcccggga gctgctactc ctgggcatgg
     3061 gaaatgagct catgcgggca gagctggaga ggatcacggg tagccggaag catgtgatca
     3121 tccacacaga ccctcgggac atgttcagcc aaatcccaga gctgcagagg aggctatgta
     3181 gccaaccacg gccaggctgc caggcacagt cactagacct ggtcttcctg ttggatgcct
     3241 ctgcctcagt gggaggtgag aactttgctc aaatgcagag cttcatcagg aaatgcaccc
     3301 tccgctttga tgtgaatcct gacgtgacac aggttggcct ggtggtatac ggtaaccagg
     3361 tgcagaccgc tttcggactt gacacccatc ccacccgtgc ttctgtgctg cgggccatga
     3421 gccaggcccc ctacctaggg ggtgtgggct ctgctggcac agccttgctg cacattgagg
     3481 acaaggtgat gacggtccag aggggagccc gccccggtgt ccccaaggct gtggtgatgc
     3541 tcacaggtgg cagtggggca gaagatgcag ctgtccctgc ccagaagctg agagacaatg
     3601 gcatctcagt cttggtaatg agtgtgggag ctgtcctcaa ggaggcagtg aggaggcttg
     3661 ctggtccacg ggactacctg atccatgtgg cagcttacac agacctgcgg taccatcagg
     3721 acacgctcat cgagtggcta tgcagagaag ccaagcggcc agtcagcctc tgcaaaccta
     3781 gcccatgcat gaatgaaggc acctgtatcc tgaagaacgg cagttaccga tgcgagtgct
     3841 ggggtggctg ggaaggcccc cactgtgaga accgcgtctt gagaggagat gcccccatgg
     3901 cacacagctt ccgccgagag cctacaggaa gacaacagcc aaccccctcc cagcaagctc
     3961 ccaagcatgt tggagtctga aaggccctat cgtcagccaa gtaaatctcc tgggggccct
     4021 ggagcatctg cttctagctc taagagccgt tttgcccata agcctctgcc acaggggaca
     4081 ctgcttagga cagtagcagc tgtcactcac tgtggtgatg atggaaaggc ctgatgtgtc
     4141 agtatttacc tcctgtatct gtttgtacct tgttaaggta agctgccttg tcacttttcc
     4201 tgaggataag gggcaggctg gagagatctg aagacccgta tgagggtcat cacagattaa
     4261 ctagacagat gttgaaaaag gtttctgtca gagctcacca cctggtgatt ggtgcaaaag
     4321 gtgggcttct ccattttcca aaagacagct cctatggatc tagtttgaaa agggattatg
     4381 tgccatttgt gattttattt tttctggtga ccagatctat gaatagggga gacctgggaa
     4441 ggtctcagac agccatctga ccaactaacc agtttgtaca taggggaggg gcatattgtg
     4501 ggaacagtgt gtgtgattgg tctgggcgct gagcagtcac cctccagagg ggcttccttt
     4561 cagagtttac ttgggagaga gtggcagtac gttggctgcc ctcctcttag tggtggcagt
     4621 gatgggcaga cttctcaaac tcagcaagtg aggggtgagg ggtgcccggg aggtgtgctc
     4681 tcaaaccttt ctatgctgtt ctgtcttaat atgtgtcttg tgcccagtcg gtaatgtttc
     4741 aagacagatt ggtcatttgt ccctcaggac tatttgtatc ccctggcaac gcagattctt
     4801 tggactatcc ttggcaaact agatacttaa ctgcagcact aacacatccg ttccccaccc
     4861 ccctgctgtt tgaagctggg ttttcagaag aagtgatttg tagagctctg ggagctacag
     4921 gacagcatct gagaagcact ggtaatgaca cgtcccatgt gcggccagtg ccgtaaactg
     4981 tccgtgttct gtgcgccagt ctggctggct gagacactac tccaggtttg cagtattttt
     5041 tccccttcac atttacactg ggatgtgaat gtgacatact gttacatttc aatcattgaa
     5101 ccgatttgta gacgtcaccg caaagcagtg ctcactttat catggaacac tagggtttcc
     5161 caaacttctg cccagctgtt gtcatagtac cttctggtaa actcttctct gcgtcagaac
     5221 ttaacagctt tcttgtcatt ctgctatatt ctactttact ttggggttgt cggcaccagg
     5281 ttcaaggagt cagaatttgg tcttgatgat ttttaaacat aaaataaaac atttatgttc
     5341 caaa
//
