LOCUS       NM_001013938            2357 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus von Willebrand factor A domain containing 1
            (Vwa1), mRNA.
ACCESSION   NM_001013938 XM_233714
VERSION     NM_001013938.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2357)
  AUTHORS   Barallobre-Barreiro,J., Oklu,R., Lynch,M., Fava,M., Baig,F.,
            Yin,X., Barwari,T., Potier,D.N., Albadawi,H., Jahangiri,M.,
            Porter,K.E., Watkins,M.T., Misra,S., Stoughton,J. and Mayr,M.
  TITLE     Extracellular matrix remodelling in response to venous
            hypertension: proteomics of human varicose veins
  JOURNAL   Cardiovasc Res 110 (3), 419-430 (2016)
   PUBMED   27068509
REFERENCE   2  (bases 1 to 2357)
  AUTHORS   Allen,J.M., Zamurs,L., Brachvogel,B., Schlotzer-Schrehardt,U.,
            Hansen,U., Lamande,S.R., Rowley,L., Fitzgerald,J. and Bateman,J.F.
  TITLE     Mice lacking the extracellular matrix protein WARP develop normally
            but have compromised peripheral nerve structure and function
  JOURNAL   J Biol Chem 284 (18), 12020-12030 (2009)
   PUBMED   19279005
REFERENCE   3  (bases 1 to 2357)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   4  (bases 1 to 2357)
  AUTHORS   Manabe,R., Tsutsui,K., Yamada,T., Kimura,M., Nakano,I., Shimono,C.,
            Sanzen,N., Furutani,Y., Fukuda,T., Oguri,Y., Shimamoto,K.,
            Kiyozumi,D., Sato,Y., Sado,Y., Senoo,H., Yamashina,S., Fukuda,S.,
            Kawai,J., Sugiura,N., Kimata,K., Hayashizaki,Y. and Sekiguchi,K.
  TITLE     Transcriptome-based systematic identification of extracellular
            matrix proteins
  JOURNAL   Proc Natl Acad Sci U S A 105 (35), 12849-12854 (2008)
   PUBMED   18757743
REFERENCE   5  (bases 1 to 2357)
  AUTHORS   Allen,J.M., Brachvogel,B., Farlie,P.G., Fitzgerald,J. and
            Bateman,J.F.
  TITLE     The extracellular matrix protein WARP is a novel component of a
            distinct subset of basement membranes
  JOURNAL   Matrix Biol 27 (4), 295-305 (2008)
   PUBMED   18314316
REFERENCE   6  (bases 1 to 2357)
  AUTHORS   Palmer,D.J., Kelly,V.C., Smit,A.M., Kuy,S., Knight,C.G. and
            Cooper,G.J.
  TITLE     Human colostrum: identification of minor proteins in the aqueous
            phase by proteomics
  JOURNAL   Proteomics 6 (7), 2208-2216 (2006)
   PUBMED   16502470
REFERENCE   7  (bases 1 to 2357)
  AUTHORS   Allen,J.M., Bateman,J.F., Hansen,U., Wilson,R., Bruckner,P.,
            Owens,R.T., Sasaki,T., Timpl,R. and Fitzgerald,J.
  TITLE     WARP is a novel multimeric component of the chondrocyte
            pericellular matrix that interacts with perlecan
  JOURNAL   J Biol Chem 281 (11), 7341-7349 (2006)
   PUBMED   16407285
REFERENCE   8  (bases 1 to 2357)
  AUTHORS   Fitzgerald,J., Tay Ting,S. and Bateman,J.F.
  TITLE     WARP is a new member of the von Willebrand factor A-domain
            superfamily of extracellular matrix proteins
  JOURNAL   FEBS Lett 517 (1-3), 61-66 (2002)
   PUBMED   12062410
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC081983.1.
            
            On Apr 20, 2005 this sequence version replaced XM_233714.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081983.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2357
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2357
                     /gene="Vwa1"
                     /gene_synonym="RGD1311476"
                     /note="von Willebrand factor A domain containing 1"
                     /db_xref="GeneID:298683"
                     /db_xref="RGD:1311476"
     exon            1..120
                     /gene="Vwa1"
                     /gene_synonym="RGD1311476"
                     /inference="alignment:Splign:2.1.0"
     CDS             48..1295
                     /gene="Vwa1"
                     /gene_synonym="RGD1311476"
                     /note="von Willebrand factor A domain-containing protein
                     1"
                     /codon_start=1
                     /product="von Willebrand factor A domain-containing
                     protein 1 precursor"
                     /protein_id="NP_001013960.1"
                     /db_xref="GeneID:298683"
                     /db_xref="RGD:1311476"
                     /translation="MLFWTVLSMALSLRLALAQSGIERGPTASAPQGDLLFLLDSSAS
                     VSHYEFSRVREFVGQLVATMPFGPGALRASLVHVGSRPHTEFTFDQYSSGQAIQDAVR
                     VAPQRMGDTNTGLALAYAKEQLFAEEAGARLGVPKVLVWVTDGASSDSVGPPMQELKD
                     LGVTIFIVSTGRGNLLELLAAASAPAEKHLHFVDVDDLPIIARELRGAIIDAMQPHQL
                     HASEILSNGFRLSWPPLLTADSGYYVLELVPSGKLAATRRQQLPGNATSWTWTDLNPD
                     TDYEVSLLPESNVRLLRPQHLRVRTLQEEAGPERIVISHTRPRSLRVSWAPALGPDST
                     LGYLVQLGPLQGGSLEHVEVPAGQNSTTIQGLTPCTTYLVTVTAAFRSGRQRALSAKA
                     CTASGERIRVPQAMRPEAGLREP"
     exon            121..678
                     /gene="Vwa1"
                     /gene_synonym="RGD1311476"
                     /inference="alignment:Splign:2.1.0"
     exon            679..957
                     /gene="Vwa1"
                     /gene_synonym="RGD1311476"
                     /inference="alignment:Splign:2.1.0"
     exon            958..2336
                     /gene="Vwa1"
                     /gene_synonym="RGD1311476"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttagctgcc agctgtggtc ggtcaggagc ccgccactcc aggcgcgatg ctgttctgga
       61 ctgtgctcag catggctttg agtctgcggt tggcactggc gcagagcggc atagagcgcg
      121 gtcccacagc atcagccccc cagggggacc tgttgttcct gctggacagc tcagccagtg
      181 tgtcacacta tgagttctca agagttcgag agtttgtggg gcagctggtg gctacgatgc
      241 ctttcggacc cggggctctg cgtgctagtc tggtgcacgt gggcagccgg cctcacacgg
      301 agtttacttt tgatcagtac agttcaggcc aggccataca ggatgctgta cgtgttgcgc
      361 cccaacgtat gggtgacacc aacacgggcc tggcactggc ttatgccaaa gaacaattat
      421 ttgctgagga agcaggtgcc cggctagggg ttcccaaggt actggtgtgg gtgacagatg
      481 gggcctccag tgactctgtg ggccccccta tgcaggagct caaggacctg ggtgtcacca
      541 tcttcattgt cagcactggc cgaggcaacc tgttggagct gttggcagct gcctcagctc
      601 cggctgagaa gcacctacac tttgtggatg tggatgacct tcctatcatt gcccgggagc
      661 ttcggggtgc cattattgat gcgatgcagc cacatcagct tcatgcctcg gagattctgt
      721 ccaatggctt ccgcctgtcc tggccgcccc tgctgacagc ggactctggt tactacgtgc
      781 tggagttggt gcccagtggc aaactggcag ccacaagacg ccaacagctg cccgggaatg
      841 ctaccagctg gacctggacc gacctcaacc cagacacaga ttacgaagta tcgctgttgc
      901 cggagtccaa tgtgcgcctc ctgaggcccc agcacttgcg agtacgcaca ctgcaagagg
      961 aggcagggcc agaacgcatc gtcatctcgc atactaggcc gcgcagcctc cgtgtaagtt
     1021 gggcccccgc acttggcccg gactccactc tcggctacct tgtacagctc ggacctctgc
     1081 agggcggatc cctagaacac gtggaggtgc cagctggcca gaacagcact accatccagg
     1141 gcctgacgcc ctgcaccact tacctggtga ctgtgactgc tgccttccgc tcgggccgcc
     1201 agagggcgct gtcggctaag gcctgtacgg catctggcga gcggatccgt gtcccgcagg
     1261 ccatgcggcc ggaggccgga ctgcgggagc cctgaccttc ctgcctcgtc cacccgaggg
     1321 gccctcttcc ctaatccagt gagagaggca ccgctgctcg tggtttttct tgtggatgga
     1381 gtggggtggg gagatggggg tgctggtcct acctttgacc tgcgtaactc ctccggtcgt
     1441 ttccccactg gtcatcaccg cccttgcctg actcccggga aacctgtagc aaccctggta
     1501 gcctcacgcg caatgacaat cctctccggt tgccagtgga gttgagcaca cggtggtcct
     1561 tgggcaacat ttggtgaggg gatggacagt gtttgaggtc aggttgagac ccaggagaag
     1621 cattcaggag aggaggccac agagttttct acctgtgcca aagactgggc cctctggtgg
     1681 caaggactac acatggcttg gaggaaatgt ccaggaccct tcaagtcctg cctgtgccta
     1741 gaaagtgggt aggagaaagg gaggagagag tagtgtaggc aaggttccca aagacttcct
     1801 tagggcaagg aaaggtaggg agagataccg ggaggctgat gatgttgcca actagttttc
     1861 atcaagattt tctgccagcc tggaggccag gatctgtcag ggtcactgac tctgccttcc
     1921 tgcccaggac ctgcactggg ccccgctatc agtgcggggg ggggggtgca gagtcttcac
     1981 aggaatgggg gatgagacct tggcatgtag tacattgggg ataggagagc cctgctgtga
     2041 cagacttaca gggagtctcc tgctttagtg tagggagcaa ggtgacatgc aggtgggcta
     2101 cctcctgtca tcactactgc cctggggcat ctgacagata cctaagggta gtcaggaaca
     2161 ggcttcctct ccagtcccta tgtacgcaga gcccctcctc cccagaacct cttgccctaa
     2221 cctaagctta ctccatctct cttccccact aatgacccag actctaacaa taatacagta
     2281 agccagacgt aaactgtgcc tgcagtctca ttaaaatgct ttatttttcg tcaaaaaaaa
     2341 aaaaaaaaaa aaaaaaa
//
