LOCUS       NM_023101                726 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus vesicle transport through interaction with
            t-SNAREs 1A (Vti1a), mRNA.
ACCESSION   NM_023101 XM_346591
VERSION     NM_023101.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 726)
  AUTHORS   Milochau,A., Lagree,V., Benassy,M.N., Chaignepain,S., Papin,J.,
            Garcia-Arcos,I., Lajoix,A., Monterrat,C., Coudert,L.,
            Schmitter,J.M., Ochoa,B. and Lang,J.
  TITLE     Synaptotagmin 11 interacts with components of the RNA-induced
            silencing complex RISC in clonal pancreatic beta-cells
  JOURNAL   FEBS Lett 588 (14), 2217-2222 (2014)
   PUBMED   24882364
REFERENCE   2  (bases 1 to 726)
  AUTHORS   Wilhelm,B.G., Mandad,S., Truckenbrodt,S., Krohnert,K., Schafer,C.,
            Rammner,B., Koo,S.J., Classen,G.A., Krauss,M., Haucke,V., Urlaub,H.
            and Rizzoli,S.O.
  TITLE     Composition of isolated synaptic boutons reveals the amounts of
            vesicle trafficking proteins
  JOURNAL   Science 344 (6187), 1023-1028 (2014)
   PUBMED   24876496
REFERENCE   3  (bases 1 to 726)
  AUTHORS   Lu,Y., Zhang,Z., Sun,D., Sweeney,S.T. and Gao,F.B.
  TITLE     Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal
            dementia, is required for autophagosome maturation
  JOURNAL   Mol Cell 52 (2), 264-271 (2013)
   PUBMED   24095276
REFERENCE   4  (bases 1 to 726)
  AUTHORS   Shitara,A., Shibui,T., Okayama,M., Arakawa,T., Mizoguchi,I.,
            Sakakura,Y. and Takuma,T.
  TITLE     VAMP4 is required to maintain the ribbon structure of the Golgi
            apparatus
  JOURNAL   Mol Cell Biochem 380 (1-2), 11-21 (2013)
   PUBMED   23677696
  REMARK    Erratum:[Mol Cell Biochem. 2013 Aug;380(1-2):301. Shakakura,
            Yasunori [corrected to Sakakura, Yasunori]]
REFERENCE   5  (bases 1 to 726)
  AUTHORS   Bourassa,C.V., Meijer,I.A., Merner,N.D., Grewal,K.K.,
            Stefanelli,M.G., Hodgkinson,K., Ives,E.J., Pryse-Phillips,W.,
            Jog,M., Boycott,K., Grimes,D.A., Goobie,S., Leckey,R., Dion,P.A.
            and Rouleau,G.A.
  TITLE     VAMP1 mutation causes dominant hereditary spastic ataxia in
            Newfoundland families
  JOURNAL   Am J Hum Genet 91 (3), 548-552 (2012)
   PUBMED   22958904
REFERENCE   6  (bases 1 to 726)
  AUTHORS   Tai,G., Lu,L., Wang,T.L., Tang,B.L., Goud,B., Johannes,L. and
            Hong,W.
  TITLE     Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in
            transport from the early/recycling endosome to the trans-Golgi
            network
  JOURNAL   Mol Biol Cell 15 (9), 4011-4022 (2004)
   PUBMED   15215310
REFERENCE   7  (bases 1 to 726)
  AUTHORS   Kreykenbohm,V., Wenzel,D., Antonin,W., Atlachkine,V. and von
            Mollard,G.F.
  TITLE     The SNAREs vti1a and vti1b have distinct localization and SNARE
            complex partners
  JOURNAL   Eur J Cell Biol 81 (5), 273-280 (2002)
   PUBMED   12067063
  REMARK    GeneRIF: Data describe a novel SNARE complex containing vti1a and
            vti1b, found on small synaptic vesicles and clathrin-coated
            vesicles isolated from nerve terminals.
REFERENCE   8  (bases 1 to 726)
  AUTHORS   Antonin,W., Fasshauer,D., Becker,S., Jahn,R. and Schneider,T.R.
  TITLE     Crystal structure of the endosomal SNARE complex reveals common
            structural principles of all SNAREs
  JOURNAL   Nat Struct Biol 9 (2), 107-111 (2002)
   PUBMED   11786915
REFERENCE   9  (bases 1 to 726)
  AUTHORS   Antonin,W., Holroyd,C., Fasshauer,D., Pabst,S., Von Mollard,G.F.
            and Jahn,R.
  TITLE     A SNARE complex mediating fusion of late endosomes defines
            conserved properties of SNARE structure and function
  JOURNAL   EMBO J 19 (23), 6453-6464 (2000)
   PUBMED   11101518
REFERENCE   10 (bases 1 to 726)
  AUTHORS   Antonin,W., Riedel,D. and von Mollard,G.F.
  TITLE     The SNARE Vti1a-beta is localized to small synaptic vesicles and
            participates in a novel SNARE complex
  JOURNAL   J Neurosci 20 (15), 5724-5732 (2000)
   PUBMED   10908612
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF262221.1.
            
            On Dec 17, 2003 this sequence version replaced XM_346591.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF262221.1, SRR8487231.156339.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..726
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q55"
     gene            1..726
                     /gene="Vti1a"
                     /gene_synonym="DD6A4-2(1); Vti1"
                     /note="vesicle transport through interaction with t-SNAREs
                     1A"
                     /db_xref="GeneID:65277"
                     /db_xref="RGD:621490"
     exon            1..119
                     /gene="Vti1a"
                     /gene_synonym="DD6A4-2(1); Vti1"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..679
                     /gene="Vti1a"
                     /gene_synonym="DD6A4-2(1); Vti1"
                     /note="vti1-rp2; vesicle transport v-SNARE protein
                     Vti1-like 2; SNARE Vti1a-beta protein"
                     /codon_start=1
                     /product="vesicle transport through interaction with
                     t-SNAREs homolog 1A"
                     /protein_id="NP_075589.1"
                     /db_xref="GeneID:65277"
                     /db_xref="RGD:621490"
                     /translation="MSADFEGYEQDFAVLTAEITSKISRVPRLPPDEKKQMVANVEKQ
                     LEEARELLEQMDLEVREIPPQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNE
                     LLGDAGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDRERI
                     QRARERLRETDANLGKSSRILTGMLRRIIQNRILLVILGIIVVITILTAITFFVRGH"
     exon            120..178
                     /gene="Vti1a"
                     /gene_synonym="DD6A4-2(1); Vti1"
                     /inference="alignment:Splign:2.1.0"
     exon            179..289
                     /gene="Vti1a"
                     /gene_synonym="DD6A4-2(1); Vti1"
                     /inference="alignment:Splign:2.1.0"
     exon            290..367
                     /gene="Vti1a"
                     /gene_synonym="DD6A4-2(1); Vti1"
                     /inference="alignment:Splign:2.1.0"
     exon            368..452
                     /gene="Vti1a"
                     /gene_synonym="DD6A4-2(1); Vti1"
                     /inference="alignment:Splign:2.1.0"
     exon            453..523
                     /gene="Vti1a"
                     /gene_synonym="DD6A4-2(1); Vti1"
                     /inference="alignment:Splign:2.1.0"
     exon            524..585
                     /gene="Vti1a"
                     /gene_synonym="DD6A4-2(1); Vti1"
                     /inference="alignment:Splign:2.1.0"
     exon            586..726
                     /gene="Vti1a"
                     /gene_synonym="DD6A4-2(1); Vti1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccggccggc cgttccggag ctgccatgtc agccgacttc gaagggtacg agcaggactt
       61 cgcagtgctc actgctgaga tcaccagcaa gatttccagg gtccctcgac tccctcccga
      121 tgagaagaag caaatggttg ccaacgtgga gaaacagctc gaagaggcca gagaactgct
      181 cgaacagatg gacttggaag ttcgagaaat cccaccccaa agtcgaggaa tgtacagcaa
      241 cagaatgagg agctacaagc aagaaatggg gaaactggaa acggatttta aaaggtcacg
      301 gatcgcctac agtgacgaag tacggaatga gctcctaggg gatgctggga attcctcaga
      361 gaaccagagg gcacatctgc tggataacac ggaaaggctg gagaggtcat ctcggagact
      421 agaggctgga taccagatag cagtggagac cgagcaaatc ggccaagaga tgttggaaaa
      481 cctgagtcat gacagagaga ggatacagcg ggcacgtgag cgactccggg aaacagatgc
      541 aaacttgggg aagagctctc ggattctgac tgggatgttg cgaagaatca tccaaaaccg
      601 catcctgctc gtcatcctgg ggatcatcgt ggtcatcacc atcctgacgg ccatcacttt
      661 ttttgtcaga ggacactgag gcgtctgctc tcccttgata aacagtgatc ttggcttgtt
      721 ctgagt
//
