LOCUS       NM_001105813            2805 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus VPS53 subunit of GARP complex (Vps53), mRNA.
ACCESSION   NM_001105813 XM_001080583 XM_213395
VERSION     NM_001105813.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2805)
  AUTHORS   Topalidou I, Cattin-Ortola J, Pappas AL, Cooper K, Merrihew GE,
            MacCoss MJ and Ailion M.
  TITLE     The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo
            Sorting to Dense-Core Vesicles
  JOURNAL   PLoS Genet 12 (5), e1006074 (2016)
   PUBMED   27191843
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2805)
  AUTHORS   Schindler C, Chen Y, Pu J, Guo X and Bonifacino JS.
  TITLE     EARP is a multisubunit tethering complex involved in endocytic
            recycling
  JOURNAL   Nat Cell Biol 17 (5), 639-650 (2015)
   PUBMED   25799061
REFERENCE   3  (bases 1 to 2805)
  AUTHORS   Perez-Victoria FJ and Bonifacino JS.
  TITLE     Dual roles of the mammalian GARP complex in tethering and SNARE
            complex assembly at the trans-golgi network
  JOURNAL   Mol Cell Biol 29 (19), 5251-5263 (2009)
   PUBMED   19620288
REFERENCE   4  (bases 1 to 2805)
  AUTHORS   Liewen H, Meinhold-Heerlein I, Oliveira V, Schwarzenbacher R, Luo
            G, Wadle A, Jung M, Pfreundschuh M and Stenner-Liewen F.
  TITLE     Characterization of the human GARP (Golgi associated retrograde
            protein) complex
  JOURNAL   Exp Cell Res 306 (1), 24-34 (2005)
   PUBMED   15878329
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_001080583.1, XM_213395.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2805
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..2805
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /note="VPS53 subunit of GARP complex"
                     /db_xref="GeneID:287535"
                     /db_xref="RGD:1311391"
     exon            1..218
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..2630
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /note="vacuolar protein sorting 53 homolog; VPS53 GARP
                     complex subunit"
                     /codon_start=1
                     /product="vacuolar protein sorting-associated protein 53
                     homolog"
                     /protein_id="NP_001099283.1"
                     /db_xref="GeneID:287535"
                     /db_xref="RGD:1311391"
                     /translation="MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDQADFNA
                     VEYINTLFPTEQSLANIDDVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQK
                     AIQQLFGKIKDIKDKAEKSEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVD
                     SLEAMTRRRQYGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILAD
                     FEEAFPSQGTKRPGGPSNVLRDACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQ
                     DVAWLDKIDRRYAWVKRQLVDYEEKYGRMFPREWCMTERISVEFCHVTRTELSKIMRA
                     RAKEIEVKLLLFAIQRTTNFEGFLAKRFSGCTLTDGTLKKLESPPPSTNPFLEDETAA
                     ETEELALEKGELEQPKKPKAPDNPFHGIVSKCFEPHLYVYIESQDKNLSELIDRFVAD
                     FKAQGPPKPNTDEGGAVLPSCADLFVYYKKCMVQCSQLSTGEPMIALTTIFQKYLREY
                     AWKILSGNLPKTSSSSGGLTISSLLKEKEGSEVARFTLEELCLICSILSTAEYCLATT
                     QQLEEKLKEKVDVSLTERINLTGEMDTFSTVISSSIQLLVQDLDAACDPALIAMSKMP
                     WQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTRKYFTQFCIKFANSFIPKFITHL
                     FKCKPISMVGAEQLLLDTHSLKMVLLDLPSIGSQVVRKAPASYTKIVVKGMTRAEMIL
                     KVVMAPHEPLVVFVDNYIKLLTDCNTETFQKILDMKGLKRSEQSSMLELLRQRLPAPP
                     SGTESSSTLSLMAPTPEQESSRIRKLEKLIKKRL"
     exon            219..299
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            300..349
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            350..416
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            417..503
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            504..619
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            620..739
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            740..818
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            819..962
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1105
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1247
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            1248..1349
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            1350..1444
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..1687
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            1688..1835
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            1836..1918
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..1997
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            1998..2146
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            2147..2216
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            2217..2354
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            2355..2459
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
     exon            2460..2805
                     /gene="Vps53"
                     /gene_synonym="RGD1311391"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggaagtgcc gggctagacg agcgagtagc ggctttctcg agccctgtac ctggaggatt
       61 gcaattctgg ggtcctggtg atagacagat cacgacaggg ttggagaggg cgtcgggggc
      121 tgagcggcgg gatgatggag gaggaggaac tggagtttgt ggaggagctg gaggctgtgc
      181 tgcagctcac gccagaggtg caactagcca tcgagcaggt attcccaagc caggatcctc
      241 ttgatcaagc tgacttcaat gccgttgagt acatcaatac tctgttccca acagagcaat
      301 ctctggcaaa cattgacgat gttgtgaaca agattagact gaaaataagg agactggatg
      361 ataatatccg cactgtcgta agaggtcaga caaatgtggg acaggatgga aggcaagcac
      421 ttgaagaagc ccagaaagcc attcagcaac tctttggcaa aatcaaggat attaaagaca
      481 aagcagaaaa gtcagaacaa atggtgaaag agatcacccg agatattaag cagttagatc
      541 acgccaagcg ccacctgacc acctcgatca caacactgaa ccacctgcac atgctggcag
      601 gcggggtgga ctccttggaa gccatgacca gacgcagaca gtatggagaa gttgctaatc
      661 tccttcaggg tgtaatgaat gttctggagc actttcacaa gtacatggga atcccacaga
      721 tccgacagct ttctgaacgg gtgaaggctg cacagacaga gctaggacag caaatcctgg
      781 ctgattttga agaagcattt ccttcacagg gtaccaagag gccaggagga cccagcaatg
      841 tcctgagaga tgcgtgcctg gtggctaata ttttggaccc cagaatcaaa caagaaatca
      901 tcaaaaagtt tattaaacag catctatcag agtatctagt actttttcaa gaaaatcaag
      961 atgtcgcctg gctggacaaa attgacagac gttatgcctg ggtaaaacgc cagcttgtgg
     1021 actatgaaga gaagtatggt cggatgtttc ctcgtgagtg gtgcatgaca gagagaatct
     1081 cagtagaatt ttgccatgtg acgaggacag aactttccaa aatcatgcga gccagagcta
     1141 aggaaattga ggtgaagttg cttctttttg ccattcagag aacaactaac tttgaggggt
     1201 ttctcgcaaa acgcttctcc ggttgcacct tgacagatgg aaccctgaaa aagctggagt
     1261 ccccaccgcc atctaccaat cccttcctgg aagatgagac agcagcagag acggaggagc
     1321 tggctctgga gaagggagag ttagagcaac caaagaagcc caaagcccca gataatccat
     1381 ttcatggcat tgtttccaag tgtttcgagc ctcatctcta cgtgtacatt gagtcccagg
     1441 acaaaaacct cagtgagctg atagaccggt ttgtggcaga tttcaaagcc cagggcccac
     1501 ccaagcccaa cactgatgaa gggggtgctg tactccccag ctgtgctgac ctctttgtct
     1561 actataagaa gtgcatggta cagtgctcac agctcagcac aggcgagccc atgattgccc
     1621 tgaccaccat cttccagaag tacctccgag aatacgcctg gaaaatcctc tctggcaacc
     1681 tgcctaaaac cagcagcagc agtggggggc tgaccatcag cagcctcctc aaagagaaag
     1741 agggctcaga agtggccaga ttcactctgg aggagctgtg tctcatctgc agcatcctga
     1801 gcacagccga gtactgtctg gctaccactc agcagctaga agaaaaactc aaagaaaaag
     1861 ttgatgtgag tctgactgag cgaattaacc tcacaggaga aatggacaca ttcagcactg
     1921 tcatctccag cagcattcag ctgttggttc aagatctaga tgcagcctgt gaccctgccc
     1981 tgattgccat gagcaagatg ccgtggcaga acgtggagca tgttggtgac cagagccctt
     2041 atgtcacctc tgttattctt cacataaagc agaatgtccc catcatccgt gacaacctgg
     2101 cttccacacg gaaatacttc acacagttct gcattaaatt tgcaaattcg ttcattccca
     2161 aattcatcac ccacctcttc aagtgtaagc cgatcagcat ggtgggagca gagcagcttc
     2221 tgctggacac ccactccctg aagatggtcc tgctcgatct cccgtccatt ggctcacagg
     2281 tggtgaggaa ggcccctgcc agttacacta agattgtcgt gaaaggcatg acccgggctg
     2341 aaatgatcct caaggtggtg atggcccctc atgaaccatt ggtagtattt gttgacaact
     2401 acatcaaact ccttacagac tgcaacacag aaaccttcca gaaaatactg gatatgaagg
     2461 ggctgaagag gagtgagcag agcagcatgc tggaactttt gcggcagagg ctccctgccc
     2521 caccctcagg gacagaaagt tctagcacac tgtccctgat ggccccaaca ccagagcagg
     2581 aatcatcacg catccgaaaa cttgaaaaac tgattaaaaa gagactgtaa ggaacatgcc
     2641 gacattgcca gggtccctga gcaactgatt tctggaaacc ctcgccctta tgactccagg
     2701 tcctaagtcc tgaaggctct gaggacatta cggttattaa agtatctctc ccagaacatg
     2761 tcttactttc tatctcagtc agggacgttc agtgaagtct ggctt
//
