LOCUS       NM_033097               3196 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus VPS52 subunit of GARP complex (Vps52), mRNA.
ACCESSION   NM_033097
VERSION     NM_033097.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3196)
  AUTHORS   Topalidou,I., Cattin-Ortola,J., Pappas,A.L., Cooper,K.,
            Merrihew,G.E., MacCoss,M.J. and Ailion,M.
  TITLE     The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo
            Sorting to Dense-Core Vesicles
  JOURNAL   PLoS Genet 12 (5), e1006074 (2016)
   PUBMED   27191843
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3196)
  AUTHORS   Schindler,C., Chen,Y., Pu,J., Guo,X. and Bonifacino,J.S.
  TITLE     EARP is a multisubunit tethering complex involved in endocytic
            recycling
  JOURNAL   Nat Cell Biol 17 (5), 639-650 (2015)
   PUBMED   25799061
REFERENCE   3  (bases 1 to 3196)
  AUTHORS   Sugimoto,M., Kondo,M., Hirose,M., Suzuki,M., Mekada,K., Abe,T.,
            Kiyonari,H., Ogura,A., Takagi,N., Artzt,K. and Abe,K.
  TITLE     Molecular identification of t(w5): Vps52 promotes pluripotential
            cell differentiation through cell-cell interactions
  JOURNAL   Cell Rep 2 (5), 1363-1374 (2012)
   PUBMED   23142660
REFERENCE   4  (bases 1 to 3196)
  AUTHORS   Liewen,H., Meinhold-Heerlein,I., Oliveira,V., Schwarzenbacher,R.,
            Luo,G., Wadle,A., Jung,M., Pfreundschuh,M. and Stenner-Liewen,F.
  TITLE     Characterization of the human GARP (Golgi associated retrograde
            protein) complex
  JOURNAL   Exp Cell Res 306 (1), 24-34 (2005)
   PUBMED   15878329
REFERENCE   5  (bases 1 to 3196)
  AUTHORS   Hurt,P., Walter,L., Sudbrak,R., Klages,S., Muller,I., Shiina,T.,
            Inoko,H., Lehrach,H., Gunther,E., Reinhardt,R. and Himmelbauer,H.
  TITLE     The genomic sequence and comparative analysis of the rat major
            histocompatibility complex
  JOURNAL   Genome Res 14 (4), 631-639 (2004)
   PUBMED   15060004
REFERENCE   6  (bases 1 to 3196)
  AUTHORS   Walter,L. and Gunther,E.
  TITLE     Identification of a novel highly conserved gene in the centromeric
            part of the major histocompatibility complex
  JOURNAL   Genomics 52 (3), 298-304 (1998)
   PUBMED   9790748
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC166419.1.
            
            On Sep 12, 2009 this sequence version replaced NM_033097.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166419.1, AJ223830.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..3196
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..3196
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /note="VPS52 subunit of GARP complex"
                     /db_xref="GeneID:25218"
                     /db_xref="RGD:3618"
     exon            1..212
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..2294
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /note="SAC2 suppressor of actin mutations 2-like protein;
                     vacuolar protein sorting 52 homolog; VPS52 GARP complex
                     subunit"
                     /codon_start=1
                     /product="vacuolar protein sorting-associated protein 52
                     homolog"
                     /protein_id="NP_149088.1"
                     /db_xref="GeneID:25218"
                     /db_xref="RGD:3618"
                     /translation="MAAAATMAAAARELVLRAGASDMEEEEGPLGAGSGLQEPLQLGE
                     LDITSDEFILDEVDVHIQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDY
                     IQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISCEIRTLQEQSGAMNIRLRN
                     RQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLEQLQELDAKAAAVREQEARGTA
                     ACADVRGVLDRLRVKAVTKIREFILQKIYSFRKPMTNYQIPQTALLKYRFFYQFLLGN
                     ERATAKEVRDEYVETLSKIYLSYYRSYVGRLMKVQYEEVAEKDDLMGVEDTAKKGFFS
                     KPSLRSRNTIFTLGTRGAVISPAELEAPILVPHTAQRGEQRYPFEALFRSQHYALLDN
                     SCREYLFICEFFVVSGPAAHDLFHAVMGRTLSMTLKHLESYLADCYDAIAVFLCIHIV
                     LRFRNIAAKRDVPALDRYWEQVLALLWPRFELILEMNVQSVRSTDPQRLGGLDTRPHY
                     ITRRYAEFSSALVSINQTIPNERTLQLLGQLQVEVENFVLRVAAEFSSRKEQLVFLIN
                     NYDMMLGVLMERAADDSKEVESFQQLLNARTQEFIEELLSPPFGGLVAFVKEAEALIE
                     RGQAERLRGEEARVTQLIRGFGSSWKASVESLSQDVMRSFTNFRNGTSIIQGALTQLI
                     QLYHRFHRVLSQPQLRALPARAELINIHHLMVELKKHKPNF"
     exon            213..297
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            298..350
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            351..426
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            427..494
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            495..670
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            671..821
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            822..922
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            923..1055
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1113
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1247
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1248..1403
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1404..1522
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..1646
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1647..1742
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1743..1850
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1851..1916
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            1917..2028
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            2029..2147
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
     exon            2148..3169
                     /gene="Vps52"
                     /gene_synonym="Are1; Sacm2l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgttagctca actatctggg aaccttttgt tgctccgtag aagacgttcc aggacttgtg
       61 gctttgcttc gggaaacgga ctctcagaga ctgacagctg ccggaagtga ggctgcgggg
      121 gaatggcagc cgcggcgacc atggcggctg ctgcccggga gctggtgttg cgggccggcg
      181 cttcagatat ggaggaggag gagggcccgc tgggggctgg ttctggactc caagagcccc
      241 tacaactcgg ggagttggat atcacctctg atgaattcat cttggatgaa gtggatgttc
      301 acatccaggc aaatctggaa gacgagttag tgaaggaagc tctcaaaacg ggtgtggatc
      361 ttcgacacta ttcaaagcag gtggagctag agctgcagca gattgagcag aagtcaatcc
      421 gggactacat ccaagagagt gaaaacatag cctctctgca caatcagatc acagcctgtg
      481 atgccgtcct agagcgcatg gagcagatgc tgggagcttt tcagagcgac ctcagctcca
      541 tcagctgtga gatccgcacc ctgcaggagc agtcgggggc catgaacatc cgacttcgta
      601 accggcaggc agttcggggg aaacttgggg aactcgtcga tgggctagtg gtgccctctg
      661 ctctggtcac agcaattctc gaagctccag tgacagagcc caggttcctg gagcagctcc
      721 aggagctgga cgccaaggcg gctgcggtca gagagcagga ggcgagaggc acggccgcct
      781 gtgcagacgt cagaggcgtg ctcgaccggc tccgggtcaa ggcggtgaca aagatccgtg
      841 agttcattct ccagaagatt tactcgttcc gaaagccgat gaccaactat cagatccccc
      901 agacggccct gctgaagtac aggtttttct atcagtttct gctgggcaac gagcgtgcta
      961 cagccaagga ggtcagggat gagtacgtag agacgctgag caagatctac ctgtcatact
     1021 accgctcgta cgtggggcgg ctcatgaaag tgcagtacga ggaagttgct gagaaagacg
     1081 atctaatggg tgtagaagac acagcaaaga aaggattctt ctcgaagccg tccctgcgaa
     1141 gcaggaacac catctttacc ctgggcaccc gtggtgctgt catctcaccg gccgagctcg
     1201 aggcccccat cctggtgccc catactgccc agcgtggaga gcagaggtac ccgtttgaag
     1261 cactcttccg cagccagcac tatgccctcc ttgacaattc ttgccgtgaa tatctcttca
     1321 tctgtgaatt tttcgtcgtc tctggcccgg ctgcccatga cctgttccac gccgtcatgg
     1381 gccgcacgct gtccatgacg ctgaaacacc tggagtccta cctggccgac tgctacgacg
     1441 ccattgctgt ttttctctgt atccacatcg ttctccggtt ccgcaacata gcagcaaaga
     1501 gggacgtccc tgccctggac agatactggg agcaggtgct ggccctgctg tggcctcgat
     1561 ttgagctcat cctggagatg aatgtgcaga gcgtccgcag cactgacccc cagcgcctcg
     1621 gggggctgga cacccggccc cactatatca cacgccgcta cgccgagttc tcctccgcgc
     1681 ttgtcagcat caaccagacc atccccaatg agcgcacgct gcagctgctg ggacagctac
     1741 aggtggaggt ggagaacttt gtcctccgcg tggctgcgga gttctcctcc aggaaggagc
     1801 agctcgtgtt tctgatcaac aactatgaca tgatgctggg tgtgctgatg gagcgggctg
     1861 ctgacgacag caaagaggtg gagagtttcc agcagctgct caatgctcgg acacaggagt
     1921 tcattgaaga gttgctgtca cccccctttg gaggtctggt ggcatttgtg aaggaggctg
     1981 aagccttgat tgagcgtggg caggctgagc ggctccgagg ggaggaagcc cgagtcaccc
     2041 agctgatccg cggctttggt agttcctgga aggcgtcagt ggagtccctg agtcaggatg
     2101 taatgcggag ttttaccaac tttcgaaatg gaaccagcat catccagggg gcgctcacac
     2161 agctgatcca gctctaccat cgcttccacc gtgtgctgtc ccagcctcag ctccgtgccc
     2221 tccctgccag ggccgaactc atcaacatcc atcacctcat ggtggagctg aagaaacaca
     2281 agccgaactt ctgattcaga ccccggggcc cgaagctccc atgggctctg cagtcacaca
     2341 gtgtctgtca cctgggaccc ctttcctgtt cctgatgtct ctaaggcttt cacacacctc
     2401 actcagcctc cattgccagg actctgcctc aacagagtgt gccctcggcc actccctggg
     2461 cttctgaggt gaccttcata gcccagccca gccccctcct ctgctgttca ctcacagcct
     2521 gtgagctctc accgccccag tccctgactg acactcggct ctcatggcag agcggtgcag
     2581 gccacactgc ccacgctgca gctgatcttc aggctccact gggacagtgg catcagctcc
     2641 cggcgggtgc actctgcctg tggcaataca gtacttactg tgctgggacg tgtcctcccc
     2701 tgtgtccctg ggtccagcat ttctttattg tagacctagt cagttcctgg tgggctgcag
     2761 caagggtggg gtagtagccc gaggactgtt ggtgcttctg gcccaggggt ggcatagtgg
     2821 ctcaggtgag gactgttttt acctctccag gagggtggca cacgccacag gcctgggaag
     2881 gtgagagctc tgtgcactgt cttgagggct gccatgggag aatccacaca gactctgaga
     2941 ttgtctgtgt tgtcctctaa gtggctgtca cagctccttt gagagtggag ggcctgtaat
     3001 acctgcaccc atgtgtcgag gcaggggtgg acctagtccc aaaacagacc ttgtcatgtc
     3061 catgtgaccc agacccttcc cactgccctc tgccccacct ctgtatggag tttccagagc
     3121 agtggttctc aaccttcctg agactcttta atacagttct tcatggtaaa aaaaaaaaaa
     3181 aaaaaaaaaa aaaaaa
//
