LOCUS       NM_172072               2034 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus vacuolar protein sorting 45 homolog (Vps45),
            mRNA.
ACCESSION   NM_172072
VERSION     NM_172072.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2034)
  AUTHORS   Boyken,J., Gronborg,M., Riedel,D., Urlaub,H., Jahn,R. and Chua,J.J.
  TITLE     Molecular profiling of synaptic vesicle docking sites reveals novel
            proteins but few differences between glutamatergic and GABAergic
            synapses
  JOURNAL   Neuron 78 (2), 285-297 (2013)
   PUBMED   23622064
REFERENCE   2  (bases 1 to 2034)
  AUTHORS   Burkhardt,P., Hattendorf,D.A., Weis,W.I. and Fasshauer,D.
  TITLE     Munc18a controls SNARE assembly through its interaction with the
            syntaxin N-peptide
  JOURNAL   EMBO J 27 (7), 923-933 (2008)
   PUBMED   18337752
REFERENCE   3  (bases 1 to 2034)
  AUTHORS   Richardson,S.C., Winistorfer,S.C., Poupon,V., Luzio,J.P. and
            Piper,R.C.
  TITLE     Mammalian late vacuole protein sorting orthologues participate in
            early endosomal fusion and interact with the cytoskeleton
  JOURNAL   Mol Biol Cell 15 (3), 1197-1210 (2004)
   PUBMED   14668490
REFERENCE   4  (bases 1 to 2034)
  AUTHORS   Bock,J.B., Klumperman,J., Davanger,S. and Scheller,R.H.
  TITLE     Syntaxin 6 functions in trans-Golgi network vesicle trafficking
  JOURNAL   Mol Biol Cell 8 (7), 1261-1271 (1997)
   PUBMED   9243506
REFERENCE   5  (bases 1 to 2034)
  AUTHORS   El-Husseini,A.E., Guthrie,H., Snutch,T.P. and Vincent,S.R.
  TITLE     Molecular cloning of a mammalian homologue of the yeast vesicular
            transport protein vps45
  JOURNAL   Biochim Biophys Acta 1325 (1), 8-12 (1997)
   PUBMED   9106478
REFERENCE   6  (bases 1 to 2034)
  AUTHORS   Tellam,J.T., James,D.E., Stevens,T.H. and Piper,R.C.
  TITLE     Identification of a mammalian Golgi Sec1p-like protein, mVps45
  JOURNAL   J Biol Chem 272 (10), 6187-6193 (1997)
   PUBMED   9045632
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC081705.1.
            
            On Sep 16, 2004 this sequence version replaced NM_172072.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081705.1, U81160.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2034
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..2034
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /note="vacuolar protein sorting 45 homolog"
                     /db_xref="GeneID:64516"
                     /db_xref="RGD:621267"
     exon            1..144
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..1764
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /note="rvps45; vesicular transport protein rvps45"
                     /codon_start=1
                     /product="vacuolar protein sorting-associated protein 45"
                     /protein_id="NP_742069.1"
                     /db_xref="GeneID:64516"
                     /db_xref="RGD:621267"
                     /translation="MNVVFAVKQYISKMIEDSGPGMKVLLMDKETTGIVSMVYTQSEI
                     LQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVDSLIQELRRPKYSIYFIYFSNVI
                     SKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSLNILGCCQGRNWDPAQLSRTTQ
                     GLTALLLSLKKCPMIRYQLSSEAAKRLGECVKQVISKEYELFEFRRTEVPPLLLILDR
                     CDDAITPLLNQWTYQAMVHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNM
                     YLNFAEIGSNIKNLMEDFQKKRPKEQQKLESIADMKAFVENYPQFKKMSGTVSKHVTV
                     VGELSRLVSERNLLEVSEVEQELACQNDHSSALQNVKRLLQNPKVTEFDAVRLVMLYA
                     LHYERHSSNSLPGLIVDLRSKGVAEKYRKLVSAVVEYGGKRVRGSDLFSPKDAVAITK
                     QFLKGLKGVENVYTQHQPFLHETLDHLIKGKLKENLYPYLGPSTLRDRPQDIIVFVIG
                     GATYEEALTVYNLNRTTPGVRIVLGGTTIHNTKSFLEEVLASGLHSRSRESSQATSRS
                     ASRR"
     exon            145..279
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     exon            280..340
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     exon            341..420
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     exon            421..489
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     exon            490..627
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     exon            628..738
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     exon            739..873
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     exon            874..987
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1155
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1314
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     exon            1315..1422
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     exon            1423..1544
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     exon            1545..1676
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
     exon            1677..1997
                     /gene="Vps45"
                     /gene_synonym="Vsp45a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagccaggaa agtgggtggg gagggtgtgg ggcacctgtc aattcgccac catgaacgtg
       61 gtctttgctg tgaagcagta tatttccaaa atgatagaag acagcggacc cggcatgaag
      121 gtacttctca tggataaaga gacgactggt atagtgagca tggtctacac acagtcagag
      181 attcttcaga aggaagtata cctcttcgaa cgaattgatt ctcaaaatcg agagatcatg
      241 aaacacctaa aagcaatttg tttccttcga cctacaaagg agaatgtgga ttctctgatc
      301 caggagctcc gaagacccaa gtatagcata tattttattt atttcagtaa tgtgatcagc
      361 aagagtgacg tgaagtcctt ggctgaagct gacgagcagg aagttgtggc tgaagttcag
      421 gaattttatg gagattatat tgctgtgaat ccacatttgt tttccctcaa tatcttgggc
      481 tgctgtcagg gtcgaaattg ggatccagcc cagctatcca gaaccactca agggctgacc
      541 gctctccttt tgtctctgaa gaagtgtccc atgattcgtt atcagctttc atcagaggct
      601 gcaaagagac tgggagagtg tgttaagcaa gtgataagta aagagtatga actctttgag
      661 ttccggcgga cagaggttcc tccactgctt ctcattctgg atcgctgcga tgacgccatc
      721 accccactgc tcaaccagtg gacatatcag gccatggtcc atgaactact gggcataaac
      781 aacaaccgga ttgatctttc cagagtgcca ggaatcagca aagacttaag agaggtggtc
      841 ctgtccgctg aaaatgatga attctatgct aataacatgt acctgaactt tgccgagatt
      901 ggtagcaata taaagaatct catggaagat ttccagaaga agagaccgaa agagcagcaa
      961 aagctagagt ccatagcgga catgaaggcc tttgttgaaa attatccaca attcaagaag
     1021 atgtctggga ctgtctcaaa gcatgtgaca gtcgttggag aactgtctcg gttggtcagt
     1081 gaacgaaacc tgctggaggt ttcagaggtt gagcaagaac tggcctgtca gaatgaccat
     1141 tctagtgctc ttcagaatgt gaagagactc ctgcagaatc cgaaagttac agaatttgat
     1201 gcagttcgcc tagtgatgct ttatgctcta cattatgagc gccacagcag caacagcctg
     1261 ccagggctca tagtggacct caggagtaaa ggtgtcgctg agaaatatcg gaagcttgtg
     1321 tctgcagttg ttgaatatgg tggtaaacgg gttagaggaa gtgacctctt cagccccaaa
     1381 gatgctgtgg ctattaccaa acagttcctc aaaggcctga agggagtgga aaatgtgtac
     1441 acccagcacc agccttttct gcatgagacc ctggaccatc tcatcaaagg gaagcttaag
     1501 gaaaacctct atccgtattt aggccccagc acactcagag acaggcctca ggacatcatc
     1561 gtgttcgtta ttggaggagc cacctatgaa gaggcactga cagtctataa cctcaaccgt
     1621 accactcctg gagtgaggat cgttctggga ggaacaacaa tacacaacac aaaaagtttc
     1681 ctagaggaag tcctggcttc tgggctgcac agccgcagca gagagagctc acaggccacc
     1741 tcaaggtcag caagcagaag atgagatggc agttgagaac agagagaatg tcacggcctc
     1801 cctcttatcc cgtctcggcc ttccctgtga ccaggggctt cagggtagct cttgtgtttg
     1861 ctctaactca ctccaggtaa ccctgattcc tgaactgctg gcacacacgc cggctgggac
     1921 tgccaatgat gagcccaccc caacccactt gtgattctgt atcaaataaa tatgttcttt
     1981 gtgtatttga cagcacaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//
