LOCUS       NM_001105928            2520 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus VPS37B subunit of ESCRT-I (Vps37b), mRNA.
ACCESSION   NM_001105928 XM_001074854 XM_213769
VERSION     NM_001105928.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2520)
  AUTHORS   Okumura,M., Katsuyama,A.M., Shibata,H. and Maki,M.
  TITLE     VPS37 isoforms differentially modulate the ternary complex
            formation of ALIX, ALG-2, and ESCRT-I
  JOURNAL   Biosci Biotechnol Biochem 77 (8), 1715-1721 (2013)
   PUBMED   23924735
REFERENCE   2  (bases 1 to 2520)
  AUTHORS   Agromayor,M., Soler,N., Caballe,A., Kueck,T., Freund,S.M.,
            Allen,M.D., Bycroft,M., Perisic,O., Ye,Y., McDonald,B., Scheel,H.,
            Hofmann,K., Neil,S.J., Martin-Serrano,J. and Williams,R.L.
  TITLE     The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA
            domain
  JOURNAL   Structure 20 (3), 414-428 (2012)
   PUBMED   22405001
REFERENCE   3  (bases 1 to 2520)
  AUTHORS   Boura,E. and Hurley,J.H.
  TITLE     Structural basis for membrane targeting by the MVB12-associated
            beta-prism domain of the human ESCRT-I MVB12 subunit
  JOURNAL   Proc Natl Acad Sci U S A 109 (6), 1901-1906 (2012)
   PUBMED   22232651
REFERENCE   4  (bases 1 to 2520)
  AUTHORS   Bajorek,M., Morita,E., Skalicky,J.J., Morham,S.G., Babst,M. and
            Sundquist,W.I.
  TITLE     Biochemical analyses of human IST1 and its function in cytokinesis
  JOURNAL   Mol Biol Cell 20 (5), 1360-1373 (2009)
   PUBMED   19129479
REFERENCE   5  (bases 1 to 2520)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 2520)
  AUTHORS   Silvestri,L.S., Ruthel,G., Kallstrom,G., Warfield,K.L.,
            Swenson,D.L., Nelle,T., Iversen,P.L., Bavari,S. and Aman,M.J.
  TITLE     Involvement of vacuolar protein sorting pathway in Ebola virus
            release independent of TSG101 interaction
  JOURNAL   J Infect Dis 196 Suppl 2, S264-S270 (2007)
   PUBMED   17940959
REFERENCE   7  (bases 1 to 2520)
  AUTHORS   Morita,E., Sandrin,V., Alam,S.L., Eckert,D.M., Gygi,S.P. and
            Sundquist,W.I.
  TITLE     Identification of human MVB12 proteins as ESCRT-I subunits that
            function in HIV budding
  JOURNAL   Cell Host Microbe 2 (1), 41-53 (2007)
   PUBMED   18005716
REFERENCE   8  (bases 1 to 2520)
  AUTHORS   Stuchell,M.D., Garrus,J.E., Muller,B., Stray,K.M., Ghaffarian,S.,
            McKinnon,R., Krausslich,H.G., Morham,S.G. and Sundquist,W.I.
  TITLE     The human endosomal sorting complex required for transport
            (ESCRT-I) and its role in HIV-1 budding
  JOURNAL   J Biol Chem 279 (34), 36059-36071 (2004)
   PUBMED   15218037
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473973.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_213769.4, XM_001074854.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132262,
                              SAMD00132263 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2520
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q15"
     gene            1..2520
                     /gene="Vps37b"
                     /gene_synonym="RGD1304576"
                     /note="VPS37B subunit of ESCRT-I"
                     /db_xref="GeneID:288659"
                     /db_xref="RGD:1304576"
     exon            1..152
                     /gene="Vps37b"
                     /gene_synonym="RGD1304576"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..899
                     /gene="Vps37b"
                     /gene_synonym="RGD1304576"
                     /note="vacuolar protein sorting 37B; vacuolar protein
                     sorting 37 homolog B; VPS37B, ESCRT-I subunit"
                     /codon_start=1
                     /product="vacuolar protein sorting-associated protein 37B"
                     /protein_id="NP_001099398.1"
                     /db_xref="GeneID:288659"
                     /db_xref="RGD:1304576"
                     /translation="MAGAVSEARFAGLSLMQLHELLEDDAQLGDMVRGMEETQTVQHN
                     KEMTLASNRSLAEGNLLYQPQLDAQKARLTQKYQELQVLFEAYQIKKTKLDKQSNSAS
                     LETLLALLQAEGAKIEEDTENMAEKFLDGELPLDAFIDVYQSKRKLAHIRRVKVEKLQ
                     ELVLKGQRLPQAGVPLPPRVPEPSPATALPYPPLEATGLPSVVPRRIPPPPPPVPAGH
                     VATPFTAAMGSGQASAYPGLQCPPLPPRVGLPSQQGFSTQLVSPYPPALPQRPPPRMA
                     PHQPGFILQ"
     exon            153..324
                     /gene="Vps37b"
                     /gene_synonym="RGD1304576"
                     /inference="alignment:Splign:2.1.0"
     exon            325..407
                     /gene="Vps37b"
                     /gene_synonym="RGD1304576"
                     /inference="alignment:Splign:2.1.0"
     exon            408..2520
                     /gene="Vps37b"
                     /gene_synonym="RGD1304576"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcttggcg gccggagcgg cggcggcggc cgagtggcgg gatggcgggc gccgtgagcg
       61 aggcgcgctt cgcggggctg tcgctgatgc agctgcacga gctgctggag gacgatgccc
      121 agctcggcga catggtgcgg gggatggagg agacgcagac tgttcagcat aacaaagaga
      181 tgacactggc tagcaaccgg agcctggcag agggaaacct tttgtaccag ccccaactgg
      241 atgctcagaa ggcgcgcctg acccaaaaat accaggaact ccaggttctc tttgaggcct
      301 atcagataaa gaagaccaaa ctagataaac aatctaacag cgcttccttg gagacgctgt
      361 tagcgcttct tcaagcagaa ggggccaaga ttgaggaaga cactgagaac atggcagaga
      421 agtttctgga tggagagctt cctctagatg cctttattga tgtctaccag agcaagcgga
      481 agctggcaca catacgacgt gtcaaagtgg agaagctcca ggagctggtg ctgaagggac
      541 agagactccc acaagccggg gtcccacttc caccccgggt gcccgagcca tcacctgcca
      601 ccgcccttcc ctacccacct ctggaggcca ctgggctccc ttctgttgtg cctcggcgca
      661 tccccccacc tccacccccg gtgcctgcag gacacgtagc caccccgttc actgctgcca
      721 tgggctcagg acaggcttct gcgtacccag gattacagtg cccacctctg cctcccagag
      781 tgggcctccc ctctcagcaa ggattctcca cacagttggt gtcaccgtac ccaccagccc
      841 tgccccagag accccctcca cggatggctc ctcaccagcc aggcttcatc ctgcagtgag
      901 ctcaggggcc tactcttcct tcaagacatc ctctgcctgc cgtgccgagc tctgcacaca
      961 caggctgtga ggttcagctt ctgggccaag ggcttggatg ccctgggcca gtgtgtccgt
     1021 ctgactttag aactgtaggt ccgtggtaag taagtaatag agagccggtt ttgtgcacca
     1081 agggagctct gtttgtacca ggccagtcag catcacatcg gtctgtgttc tgggtgtgat
     1141 ttctgagtgt ctagtgttgt tgatggactc gtgcatttgg aaagataaac ctcccccctc
     1201 caatttagaa tcatggccct cctgttgcag ctttatttaa taagcatgat taattatgtc
     1261 tgttttattt tcaagtcttg gcccaccagc tgctgtggca ctagtaaagg ctggtctaca
     1321 gcggccagcc ggagcgtgtg ccggtgccca ggccatgctg ggcagctatg ctgttcattg
     1381 aatctgtgca gggcagggca tcacagtgac ctcgtgttcc cgccaagctg gatgctttca
     1441 tggttccaag tcacaggcag aatttgcact tggctgctgt gtgcagaggc caggagagct
     1501 gtggccctgg gggtgaggcc agtgtgttgc acagtacagc cctcagccct cccctcacac
     1561 cgtcaagccg catgacggtt tctgtgaaaa aaatactcag tgtttttact acacttgtaa
     1621 ttttcctgtt ttatatttca aaagaaaact tttttgacac tctcaagacc attcagggaa
     1681 acttttttaa aaatgcagat agactgtttt gagttggtta aaaatgcaga tttattgagt
     1741 gccgcttcct gtcaggcgag cagtgcgtgg tcacatccgt ccgtggccgt gctgtgcctt
     1801 agcttcacct ggtgccaggg ctcagatgcc tgcagcgtgc cagccacagc tgccctacag
     1861 agccgttagg cggggcctaa caggccacat cactttgtga caggtcagaa agggtccctc
     1921 ctcctccaac caggatgact taggcagctg gctgtgctgc aggtgtcggc caaggcacgg
     1981 aatgggtttg gggaaggccc accccacagg attggcggca gcagctccgt cctctctggg
     2041 acctcatctg caggtgcccc atgtgcagag ttcccaaggc ccagccgggg aggggcagtc
     2101 ccacacctgt tctgcgaaga gggctgcgcg actgttggta gaactcagaa ccccctccac
     2161 cctgccagct ggctgcagcc cagggcaaca gtcaaggcag cgctggttag agcctgtccc
     2221 agctgggcca ccggcaggac catcagcctt tgtccccaag tcatcctata ttcctcatca
     2281 cggatttgga ctctgtaccc tactggaact attctgtaga gacaaagctg tatgtgccac
     2341 ctcaatacct ctgccaccag ctgccaccag gaacgcccac tgcccagtcc tgggctgcag
     2401 ccacatggga gctccaggtg gatgtaggaa aggggctgcc aggctgacct tgccgggcca
     2461 gagctggcac cgtggctgta aaggtgtaga cctcttaata aattgagaat tattaatttc
//
