LOCUS       NM_001106092            1323 bp    mRNA    linear   ROD 10-DEC-2024
DEFINITION  Rattus norvegicus vacuolar protein sorting 36 homolog (Vps36),
            mRNA.
ACCESSION   NM_001106092 XM_001064954 XM_214382
VERSION     NM_001106092.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1323)
  AUTHORS   Gorbea,C., Pratt,G., Ustrell,V., Bell,R., Sahasrabudhe,S.,
            Hughes,R.E. and Rechsteiner,M.
  TITLE     A protein interaction network for Ecm29 links the 26 S proteasome
            to molecular motors and endosomal components
  JOURNAL   J Biol Chem 285 (41), 31616-31633 (2010)
   PUBMED   20682791
REFERENCE   2  (bases 1 to 1323)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   3  (bases 1 to 1323)
  AUTHORS   Wang,T. and Hong,W.
  TITLE     RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their
            membrane recruitment
  JOURNAL   Biochem Biophys Res Commun 350 (2), 413-423 (2006)
   PUBMED   17010938
REFERENCE   4  (bases 1 to 1323)
  AUTHORS   Langelier,C., von Schwedler,U.K., Fisher,R.D., De Domenico,I.,
            White,P.L., Hill,C.P., Kaplan,J., Ward,D. and Sundquist,W.I.
  TITLE     Human ESCRT-II complex and its role in human immunodeficiency virus
            type 1 release
  JOURNAL   J Virol 80 (19), 9465-9480 (2006)
   PUBMED   16973552
REFERENCE   5  (bases 1 to 1323)
  AUTHORS   Slagsvold,T., Aasland,R., Hirano,S., Bache,K.G., Raiborg,C.,
            Trambaiolo,D., Wakatsuki,S. and Stenmark,H.
  TITLE     Eap45 in mammalian ESCRT-II binds ubiquitin via a
            phosphoinositide-interacting GLUE domain
  JOURNAL   J Biol Chem 280 (20), 19600-19606 (2005)
   PUBMED   15755741
REFERENCE   6  (bases 1 to 1323)
  AUTHORS   Kamura,T., Burian,D., Khalili,H., Schmidt,S.L., Sato,S., Liu,W.J.,
            Conrad,M.N., Conaway,R.C., Conaway,J.W. and Shilatifard,A.
  TITLE     Cloning and characterization of ELL-associated proteins EAP45 and
            EAP20. a role for yeast EAP-like proteins in regulation of gene
            expression by glucose
  JOURNAL   J Biol Chem 276 (19), 16528-16533 (2001)
   PUBMED   11278625
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC160860.1.
            
            On May 29, 2008 this sequence version replaced NM_001106092.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC160860.1, FQ217181.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1323
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.5"
     gene            1..1323
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /note="vacuolar protein sorting 36 homolog"
                     /db_xref="GeneID:290851"
                     /db_xref="RGD:1309754"
     exon            1..123
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..1188
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /note="ESCRT-II complex subunit VPS36; ELL-associated
                     protein of 45 kDa"
                     /codon_start=1
                     /product="vacuolar protein-sorting-associated protein 36"
                     /protein_id="NP_001099562.2"
                     /db_xref="GeneID:290851"
                     /db_xref="RGD:1309754"
                     /translation="MDRFVWTSGLLEINETLVIQQRGVRVYDGEEKIKFDAGTLLLST
                     HRLIWRDQKNNECCMAIPLSQIVFIEEQAAGIGKSAKIVVHLHPAPPNKEPGPFQSSK
                     NSYIKLSFKEHGQIEFYRRLSEEMTQRRWETVPVSQSLQTKKGPQPGRIRAVGIVGIE
                     RKLEEKRKETDKNISEAFEDLSKLMIKAKEMVELSKSIANKIKEKQGDVTEDETIRFK
                     SYLLSMGIANPVTRETYGSGTQYHMQLAKQLAGILQAPLEERGGIMSLTEVYCLVNRA
                     RGMELLSPEDLVNACKMLEGLKLPVRLRVFDSGVMVIELQTHKEEEMVASALETVSER
                     GSLTSEEFAKLVGMSVLLAKERLLLAEKMGHLCRDDSVEGLRFYPNLFMTQN"
     exon            124..192
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
     exon            193..263
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
     exon            264..378
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
     exon            379..468
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
     exon            469..555
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
     exon            556..588
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
     exon            589..666
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
     exon            667..801
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
     exon            802..867
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
     exon            868..932
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1017
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
     exon            1018..1094
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
     exon            1095..1298
                     /gene="Vps36"
                     /gene_synonym="RGD1309754"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcagagg ccggccgggt ggcggccatg gaccgcttcg tgtggaccag cggcctcctg
       61 gagatcaacg agaccctggt gatccagcag cgaggagtgc gcgtctacga cggcgaggag
      121 aagataaaat ttgatgctgg gactcttctc cttagtacac accggctgat ttggagagac
      181 cagaaaaaca atgagtgctg catggccatt cccctatcgc agattgtgtt catcgaggag
      241 caggcggctg gaattgggaa gagtgccaaa atcgtggttc atctgcaccc agcccctcct
      301 aacaaagaac ccggcccatt ccagagcagt aagaactcct acatcaagct ctccttcaaa
      361 gagcatggtc agatcgagtt ttacaggcgt ttatcagagg agatgaccca aagaagatgg
      421 gagacagtgc cagtttccca gtcactacaa acaaagaaag gaccccagcc aggaagaata
      481 agagctgttg gaattgtagg cattgaaagg aaacttgaag aaaaaaggaa agaaacagac
      541 aaaaacattt ctgaggcctt tgaagacctg agcaagctga tgatcaaggc taaggaaatg
      601 gtagagttat caaaatcgat cgctaataag attaaagaga agcaaggcga tgtcacagaa
      661 gacgagacca tcaggtttaa gtcgtacttg ctgagcatgg gaatagccaa cccagtcacc
      721 agagaaacct atggctcagg cacacagtac cacatgcaac tggccaagca gctggccggg
      781 atattgcagg ctcccttgga ggagcgtggg ggaataatgt cactcacaga ggtgtactgt
      841 ttagtgaacc gagcccgagg aatggagttg ctctcaccag aagacttagt aaatgcatgc
      901 aagatgctgg aaggcctgaa actgcctgtc agactccggg ttttcgacag tggtgtcatg
      961 gtaattgagc ttcagactca caaggaagag gaaatggtgg cctcggcctt agagacggtt
     1021 tccgagaggg gatccttaac atcagaagag tttgccaagc ttgtgggaat gtctgtcctt
     1081 ctggctaaag aaaggctgct tcttgcggag aagatgggcc acctttgccg agatgactct
     1141 gtggaaggct tgcggtttta tccaaattta tttatgacac agaactaaga atcccgtact
     1201 tgaaatattt tttgtcaata tgcttacatt atgccaacat ctcatgacac tgagttaaga
     1261 gataaactca aataaaccaa gaatttatta gaacctcaaa aaaaaaaaaa aaaaaaaaaa
     1321 aaa
//
