LOCUS       NM_001105932            1159 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus VPS29 retromer complex component (Vps29), mRNA.
ACCESSION   NM_001105932 XM_001079533 XM_213780
VERSION     NM_001105932.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1159)
  AUTHORS   McNally,K.E., Faulkner,R., Steinberg,F., Gallon,M., Ghai,R.,
            Pim,D., Langton,P., Pearson,N., Danson,C.M., Nagele,H.,
            Morris,L.L., Singla,A., Overlee,B.L., Heesom,K.J., Sessions,R.,
            Banks,L., Collins,B.M., Berger,I., Billadeau,D.D., Burstein,E. and
            Cullen,P.J.
  TITLE     Retriever is a multiprotein complex for retromer-independent
            endosomal cargo recycling
  JOURNAL   Nat Cell Biol 19 (10), 1214-1225 (2017)
   PUBMED   28892079
REFERENCE   2  (bases 1 to 1159)
  AUTHORS   Follett,J., Bugarcic,A., Yang,Z., Ariotti,N., Norwood,S.J.,
            Collins,B.M., Parton,R.G. and Teasdale,R.D.
  TITLE     Parkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal
            Association of Retromer and Induces alpha-Synuclein Aggregation
  JOURNAL   J Biol Chem 291 (35), 18283-18298 (2016)
   PUBMED   27385586
REFERENCE   3  (bases 1 to 1159)
  AUTHORS   Gallon,M. and Cullen,P.J.
  TITLE     Retromer and sorting nexins in endosomal sorting
  JOURNAL   Biochem Soc Trans 43 (1), 33-47 (2015)
   PUBMED   25619244
  REMARK    Review article
REFERENCE   4  (bases 1 to 1159)
  AUTHORS   Hesketh,G.G., Perez-Dorado,I., Jackson,L.P., Wartosch,L.,
            Schafer,I.B., Gray,S.R., McCoy,A.J., Zeldin,O.B., Garman,E.F.,
            Harbour,M.E., Evans,P.R., Seaman,M.N.J., Luzio,J.P. and Owen,D.J.
  TITLE     VARP is recruited on to endosomes by direct interaction with
            retromer, where together they function in export to the cell
            surface
  JOURNAL   Dev Cell 29 (5), 591-606 (2014)
   PUBMED   24856514
REFERENCE   5  (bases 1 to 1159)
  AUTHORS   Popovic,D. and Dikic,I.
  TITLE     TBC1D5 and the AP2 complex regulate ATG9 trafficking and initiation
            of autophagy
  JOURNAL   EMBO Rep 15 (4), 392-401 (2014)
   PUBMED   24603492
REFERENCE   6  (bases 1 to 1159)
  AUTHORS   Kim,E., Lee,Y., Lee,H.J., Kim,J.S., Song,B.S., Huh,J.W., Lee,S.R.,
            Kim,S.U., Kim,S.H., Hong,Y., Shim,I. and Chang,K.T.
  TITLE     Implication of mouse Vps26b-Vps29-Vps35 retromer complex in
            sortilin trafficking
  JOURNAL   Biochem Biophys Res Commun 403 (2), 167-171 (2010)
   PUBMED   21040701
REFERENCE   7  (bases 1 to 1159)
  AUTHORS   Haft,C.R., de la Luz Sierra,M., Bafford,R., Lesniak,M.A., Barr,V.A.
            and Taylor,S.I.
  TITLE     Human orthologs of yeast vacuolar protein sorting proteins Vps26,
            29, and 35: assembly into multimeric complexes
  JOURNAL   Mol Biol Cell 11 (12), 4105-4116 (2000)
   PUBMED   11102511
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473973.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_001079533.1, XM_213780.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB557496.1, FQ213481.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760494
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1159
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..1159
                     /gene="Vps29"
                     /note="VPS29 retromer complex component"
                     /db_xref="GeneID:288666"
                     /db_xref="RGD:1308332"
     exon            1..86
                     /gene="Vps29"
                     /inference="alignment:Splign:2.1.0"
     CDS             84..632
                     /gene="Vps29"
                     /EC_number="3.1.3.3"
                     /note="vacuolar protein sorting 29 homolog"
                     /codon_start=1
                     /product="vacuolar protein sorting-associated protein 29"
                     /protein_id="NP_001099402.1"
                     /db_xref="GeneID:288666"
                     /db_xref="RGD:1308332"
                     /translation="MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKE
                     SYDYLKTLAGDVHIVRGDFDESLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALL
                     QRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTV
                     VTYVYQLIGDDVKVERIEYKKS"
     exon            87..278
                     /gene="Vps29"
                     /inference="alignment:Splign:2.1.0"
     exon            279..514
                     /gene="Vps29"
                     /inference="alignment:Splign:2.1.0"
     exon            515..1159
                     /gene="Vps29"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggaagaagt gggcgggtca gcgaggtgcc tgaggaagag ggcagcggcg ttcgtggtga
       61 ctgaacggaa tcccggtgac aggatgttgg tgttggtatt aggagatctg cacattccac
      121 accggtgcaa cagcctgccg gccaaattta aaaaactcct ggtgccagga aaaatccagc
      181 acattctctg cactggaaac ctttgcacca aggagagcta tgactatctc aagactctgg
      241 ctggtgatgt ccacatcgta agaggagact tcgatgagag tctgaattac ccagaacaga
      301 aggttgtgac tgtggggcag ttcaagatcg gtctgatcca tggccaccaa gttattccgt
      361 ggggagacat ggctagctta gccctgctgc agaggcagtt tgatgtggac attcttatct
      421 caggacacac acacaaattc gaagcatttg agcatgaaaa taaattctat attaacccag
      481 gttctgccac tggagcctat aatgccttgg aaacaaatat tattccgtca tttgtgctga
      541 tggacatcca ggcttctacc gtggtcactt acgtctatca gctaattgga gatgacgtaa
      601 aagtagaacg aattgagtat aaaaagtcat aaagccaggc cggtctccac cacttatttt
      661 tttctcattt ccttgttcaa atcagataat taaacactta agaggcacac agttgtatca
      721 cttttataat attttgcact aaaaagtctt ctctgttgat acagttgctc taaagcttct
      781 tgtaaactct taagaatata tttagtttgc agtatatggc ttctataaga agcagcccac
      841 cccacagtcc aggaccatgt taggaagttt gtccttgtaa atagcttccc agttggtttt
      901 ggactgcata gaaaactagt gcatgaggag aaaggatcca ggctttgtgt gtgttttctc
      961 ttctctggta ataaatgtgt accttccatt tagacgttct tgaaagcctg tgtttaattt
     1021 aaaaagcaaa cgtgaaatct cagcactcaa gaggcagagg cgggtggatc tcttcagcat
     1081 tttttgccag tttggtctac attgttaatg ctaggccagc caaaactaca caggagaccc
     1141 tgtctcaaga aaaccaaaa
//
