LOCUS       NM_001130492             977 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus VPS28 subunit of ESCRT-I (Vps28), mRNA.
ACCESSION   NM_001130492 XM_001073010 XM_216962
VERSION     NM_001130492.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 977)
  AUTHORS   Boura,E. and Hurley,J.H.
  TITLE     Structural basis for membrane targeting by the MVB12-associated
            beta-prism domain of the human ESCRT-I MVB12 subunit
  JOURNAL   Proc Natl Acad Sci U S A 109 (6), 1901-1906 (2012)
   PUBMED   22232651
REFERENCE   2  (bases 1 to 977)
  AUTHORS   Stefani,F., Zhang,L., Taylor,S., Donovan,J., Rollinson,S.,
            Doyotte,A., Brownhill,K., Bennion,J., Pickering-Brown,S. and
            Woodman,P.
  TITLE     UBAP1 is a component of an endosome-specific ESCRT-I complex that
            is essential for MVB sorting
  JOURNAL   Curr Biol 21 (14), 1245-1250 (2011)
   PUBMED   21757351
REFERENCE   3  (bases 1 to 977)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (bases 1 to 977)
  AUTHORS   Tsunematsu,T., Yamauchi,E., Shibata,H., Maki,M., Ohta,T. and
            Konishi,H.
  TITLE     Distinct functions of human MVB12A and MVB12B in the ESCRT-I
            dependent on their posttranslational modifications
  JOURNAL   Biochem Biophys Res Commun 399 (2), 232-237 (2010)
   PUBMED   20654576
  REMARK    Erratum:[Biochem Biophys Res Commun. 2011 Mar 4;406(1):158-9]
REFERENCE   5  (bases 1 to 977)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   6  (bases 1 to 977)
  AUTHORS   McDonald,B. and Martin-Serrano,J.
  TITLE     Regulation of Tsg101 expression by the steadiness box: a role of
            Tsg101-associated ligase
  JOURNAL   Mol Biol Cell 19 (2), 754-763 (2008)
   PUBMED   18077552
REFERENCE   7  (bases 1 to 977)
  AUTHORS   Silvestri,L.S., Ruthel,G., Kallstrom,G., Warfield,K.L.,
            Swenson,D.L., Nelle,T., Iversen,P.L., Bavari,S. and Aman,M.J.
  TITLE     Involvement of vacuolar protein sorting pathway in Ebola virus
            release independent of TSG101 interaction
  JOURNAL   J Infect Dis 196 Suppl 2, S264-S270 (2007)
   PUBMED   17940959
REFERENCE   8  (bases 1 to 977)
  AUTHORS   Morita,E., Sandrin,V., Alam,S.L., Eckert,D.M., Gygi,S.P. and
            Sundquist,W.I.
  TITLE     Identification of human MVB12 proteins as ESCRT-I subunits that
            function in HIV budding
  JOURNAL   Cell Host Microbe 2 (1), 41-53 (2007)
   PUBMED   18005716
REFERENCE   9  (bases 1 to 977)
  AUTHORS   Bishop,N., Horman,A. and Woodman,P.
  TITLE     Mammalian class E vps proteins recognize ubiquitin and act in the
            removal of endosomal protein-ubiquitin conjugates
  JOURNAL   J Cell Biol 157 (1), 91-101 (2002)
   PUBMED   11916981
REFERENCE   10 (bases 1 to 977)
  AUTHORS   Bishop,N. and Woodman,P.
  TITLE     TSG101/mammalian VPS23 and mammalian VPS28 interact directly and
            are recruited to VPS4-induced endosomes
  JOURNAL   J Biol Chem 276 (15), 11735-11742 (2001)
   PUBMED   11134028
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473950.2.
            
            On or before Jul 27, 2008 this sequence version replaced
            XM_001073010.1, XM_216962.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ225519.1, CF976489.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..977
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..977
                     /gene="Vps28"
                     /note="VPS28 subunit of ESCRT-I"
                     /db_xref="GeneID:300052"
                     /db_xref="RGD:1306537"
     exon            1..134
                     /gene="Vps28"
                     /inference="alignment:Splign:2.1.0"
     exon            135..203
                     /gene="Vps28"
                     /inference="alignment:Splign:2.1.0"
     CDS             167..832
                     /gene="Vps28"
                     /note="vacuolar protein sorting 28 homolog; VPS28, ESCRT-I
                     subunit"
                     /codon_start=1
                     /product="vacuolar protein sorting-associated protein 28
                     homolog"
                     /protein_id="NP_001123964.1"
                     /db_xref="GeneID:300052"
                     /db_xref="RGD:1306537"
                     /translation="MFHGIPATPGVGAPGNKPELYEEVKLYKNAREREKYDNMAELFA
                     VVKTMQALEKAYIKDCVTPNEYTAACSRLLVQYKAAFRQVQGSEISSIDEFCRKFRLD
                     CPLAMERIKEDRPITIKDDKGNLNRCIADVVSLFITVMDKLRLEIRAMDEIQPDLREL
                     METMHRMSHLPPDFEGRQTVSQWLQTLSGMSASDELDDSQVRQMLFDLESAYNAFNRF
                     LHS"
     exon            204..232
                     /gene="Vps28"
                     /inference="alignment:Splign:2.1.0"
     exon            233..270
                     /gene="Vps28"
                     /inference="alignment:Splign:2.1.0"
     exon            271..360
                     /gene="Vps28"
                     /inference="alignment:Splign:2.1.0"
     exon            361..466
                     /gene="Vps28"
                     /inference="alignment:Splign:2.1.0"
     exon            467..568
                     /gene="Vps28"
                     /inference="alignment:Splign:2.1.0"
     exon            569..622
                     /gene="Vps28"
                     /inference="alignment:Splign:2.1.0"
     exon            623..714
                     /gene="Vps28"
                     /inference="alignment:Splign:2.1.0"
     exon            715..977
                     /gene="Vps28"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attgggcttg ctatgtgcgt aggctcaagt tggagaatga gcgccgagct gccgatcggg
       61 tttcccggca ggcgcaggcg gaaaaagcga gcaccgagct tctgtcgcca tctccgggac
      121 tccaaacgcc ccaggtctct tgtgctgtag ctgacaggcc tgcaggatgt ttcacgggat
      181 cccagctact cctggtgttg gagcccctgg gaacaagccg gagctatacg aggaagtaaa
      241 gttgtacaag aatgcccggg agcgggagaa gtatgacaac atggcggagc tctttgcggt
      301 ggtgaaaacg atgcaagcgc tggagaaggc atacatcaag gactgcgtca cccccaatga
      361 gtacactgca gcctgctcca ggctcctggt ccagtacaaa gctgccttcc ggcaggtcca
      421 aggctcagag atcagctcca ttgatgaatt ttgccgaaag ttcagactgg actgcccact
      481 tgctatggag cggatcaaag aggaccgacc catcaccatc aaggacgaca agggcaatct
      541 caaccgctgt attgcggacg tcgtctcgct cttcattaca gtcatggaca agctgcgtct
      601 ggagatccgc gccatggacg agatccagcc agacctgcgg gagctaatgg agaccatgca
      661 cagaatgagc cacctgcctc cagactttga gggccgccaa acagtcagcc agtggctgca
      721 gaccctgagt ggtatgtcgg cctctgatga gctagatgac tcccaagttc gccagatgct
      781 cttcgatctg gagtcagctt acaatgcctt caaccgcttc ctacactcct gagtgtcatc
      841 gaggcaagaa agagactgat ggagatgtga cgcctcagct ccctgtgtct acacctgtcc
      901 cacatgtcta tattgtcagg acattgccca caataaagat ctctctaacc ttcctgctat
      961 gagcagttat gctgagc
//
