LOCUS       NP_001123964             221 aa            linear   ROD 03-APR-2024
DEFINITION  vacuolar protein sorting-associated protein 28 homolog [Rattus
            norvegicus].
ACCESSION   NP_001123964 XP_001073010 XP_216962
VERSION     NP_001123964.1
DBSOURCE    REFSEQ: accession NM_001130492.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 221)
  AUTHORS   Boura,E. and Hurley,J.H.
  TITLE     Structural basis for membrane targeting by the MVB12-associated
            beta-prism domain of the human ESCRT-I MVB12 subunit
  JOURNAL   Proc Natl Acad Sci U S A 109 (6), 1901-1906 (2012)
   PUBMED   22232651
REFERENCE   2  (residues 1 to 221)
  AUTHORS   Stefani,F., Zhang,L., Taylor,S., Donovan,J., Rollinson,S.,
            Doyotte,A., Brownhill,K., Bennion,J., Pickering-Brown,S. and
            Woodman,P.
  TITLE     UBAP1 is a component of an endosome-specific ESCRT-I complex that
            is essential for MVB sorting
  JOURNAL   Curr Biol 21 (14), 1245-1250 (2011)
   PUBMED   21757351
REFERENCE   3  (residues 1 to 221)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (residues 1 to 221)
  AUTHORS   Tsunematsu,T., Yamauchi,E., Shibata,H., Maki,M., Ohta,T. and
            Konishi,H.
  TITLE     Distinct functions of human MVB12A and MVB12B in the ESCRT-I
            dependent on their posttranslational modifications
  JOURNAL   Biochem Biophys Res Commun 399 (2), 232-237 (2010)
   PUBMED   20654576
  REMARK    Erratum:[Biochem Biophys Res Commun. 2011 Mar 4;406(1):158-9]
REFERENCE   5  (residues 1 to 221)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   6  (residues 1 to 221)
  AUTHORS   McDonald,B. and Martin-Serrano,J.
  TITLE     Regulation of Tsg101 expression by the steadiness box: a role of
            Tsg101-associated ligase
  JOURNAL   Mol Biol Cell 19 (2), 754-763 (2008)
   PUBMED   18077552
REFERENCE   7  (residues 1 to 221)
  AUTHORS   Silvestri,L.S., Ruthel,G., Kallstrom,G., Warfield,K.L.,
            Swenson,D.L., Nelle,T., Iversen,P.L., Bavari,S. and Aman,M.J.
  TITLE     Involvement of vacuolar protein sorting pathway in Ebola virus
            release independent of TSG101 interaction
  JOURNAL   J Infect Dis 196 Suppl 2, S264-S270 (2007)
   PUBMED   17940959
REFERENCE   8  (residues 1 to 221)
  AUTHORS   Morita,E., Sandrin,V., Alam,S.L., Eckert,D.M., Gygi,S.P. and
            Sundquist,W.I.
  TITLE     Identification of human MVB12 proteins as ESCRT-I subunits that
            function in HIV budding
  JOURNAL   Cell Host Microbe 2 (1), 41-53 (2007)
   PUBMED   18005716
REFERENCE   9  (residues 1 to 221)
  AUTHORS   Bishop,N., Horman,A. and Woodman,P.
  TITLE     Mammalian class E vps proteins recognize ubiquitin and act in the
            removal of endosomal protein-ubiquitin conjugates
  JOURNAL   J Cell Biol 157 (1), 91-101 (2002)
   PUBMED   11916981
REFERENCE   10 (residues 1 to 221)
  AUTHORS   Bishop,N. and Woodman,P.
  TITLE     TSG101/mammalian VPS23 and mammalian VPS28 interact directly and
            are recruited to VPS4-induced endosomes
  JOURNAL   J Biol Chem 276 (15), 11735-11742 (2001)
   PUBMED   11134028
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473950.2.
            
            On or before Jul 27, 2008 this sequence version replaced
            XP_001073010.1, XP_216962.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ225519.1, CF976489.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..221
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     Protein         1..221
                     /product="vacuolar protein sorting-associated protein 28
                     homolog"
                     /note="vacuolar protein sorting 28 homolog; VPS28, ESCRT-I
                     subunit"
                     /calculated_mol_wt=25337
     Region          39..219
                     /region_name="VPS28"
                     /note="VPS28 protein; pfam03997"
                     /db_xref="CDD:427639"
     CDS             1..221
                     /gene="Vps28"
                     /coded_by="NM_001130492.1:167..832"
                     /db_xref="GeneID:300052"
                     /db_xref="RGD:1306537"
ORIGIN      
        1 mfhgipatpg vgapgnkpel yeevklykna rerekydnma elfavvktmq alekayikdc
       61 vtpneytaac srllvqykaa frqvqgseis sidefcrkfr ldcplameri kedrpitikd
      121 dkgnlnrcia dvvslfitvm dklrleiram deiqpdlrel metmhrmshl ppdfegrqtv
      181 sqwlqtlsgm sasdelddsq vrqmlfdles aynafnrflh s
//
