LOCUS       NM_001106809            3576 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus VPS26 retromer complex component B (Vps26b),
            mRNA.
ACCESSION   NM_001106809 XM_001054836 XM_217099
VERSION     NM_001106809.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3576)
  AUTHORS   Gallon M and Cullen PJ.
  TITLE     Retromer and sorting nexins in endosomal sorting
  JOURNAL   Biochem Soc Trans 43 (1), 33-47 (2015)
   PUBMED   25619244
  REMARK    Review article
REFERENCE   2  (bases 1 to 3576)
  AUTHORS   Bugarcic A, Zhe Y, Kerr MC, Griffin J, Collins BM and Teasdale RD.
  TITLE     Vps26A and Vps26B subunits define distinct retromer complexes
  JOURNAL   Traffic 12 (12), 1759-1773 (2011)
   PUBMED   21920005
REFERENCE   3  (bases 1 to 3576)
  AUTHORS   Kim E, Lee Y, Lee HJ, Kim JS, Song BS, Huh JW, Lee SR, Kim SU, Kim
            SH, Hong Y, Shim I and Chang KT.
  TITLE     Implication of mouse Vps26b-Vps29-Vps35 retromer complex in
            sortilin trafficking
  JOURNAL   Biochem Biophys Res Commun 403 (2), 167-171 (2010)
   PUBMED   21040701
REFERENCE   4  (bases 1 to 3576)
  AUTHORS   Trost M, English L, Lemieux S, Courcelles M, Desjardins M and
            Thibault P.
  TITLE     The phagosomal proteome in interferon-gamma-activated macrophages
  JOURNAL   Immunity 30 (1), 143-154 (2009)
   PUBMED   19144319
REFERENCE   5  (bases 1 to 3576)
  AUTHORS   Shultz MA, Zhang L, Gu YZ, Baker GL, Fannuchi MV, Padua AM, Gurske
            WA, Morin D, Penn SG, Jovanovich SB, Plopper CG and Buckpitt AR.
  TITLE     Gene expression analysis in response to lung toxicants: I.
            Sequencing and microarray development
  JOURNAL   Am J Respir Cell Mol Biol 30 (3), 296-310 (2004)
   PUBMED   12947022
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CA334760.1, BC161865.1, CO394403.1, CA339357.1, CF113332.1,
            EV779065.1 and CB578687.1.
            
            On or before Sep 4, 2008 this sequence version replaced
            XM_217099.4, XM_001054836.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161865.1, DY310431.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760433, SAMEA5760494
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                CA334760.1         1-64
            65-1590             BC161865.1         1-1526
            1591-1656           CO394403.1         622-687
            1657-2217           CA339357.1         59-619
            2218-2566           CF113332.1         222-570
            2567-3091           EV779065.1         226-750
            3092-3576           CB578687.1         137-621
FEATURES             Location/Qualifiers
     source          1..3576
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..3576
                     /gene="Vps26b"
                     /note="VPS26 retromer complex component B"
                     /db_xref="GeneID:300472"
                     /db_xref="RGD:1597170"
     exon            1..658
                     /gene="Vps26b"
                     /inference="alignment:Splign:2.1.0"
     CDS             436..1446
                     /gene="Vps26b"
                     /note="vacuolar protein sorting 26 homolog B"
                     /codon_start=1
                     /product="vacuolar protein sorting-associated protein 26B"
                     /protein_id="NP_001100279.1"
                     /db_xref="GeneID:300472"
                     /db_xref="RGD:1597170"
                     /translation="MSFFGFGQSVEVEILLNDAESRKRAEHKTEDGKKEKYFLFYDGE
                     TVSGKVSLSLKNPNKRLEHQGIKIEFIGQIELYYDRGNHHEFVSLVKDLARPGEITQS
                     QAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLNDVVKEMDIVVHTLSTYPELNS
                     SIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTG
                     PNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVL
                     IDEEERRYFKQQEVVLWRKGDIVRKSMSHQAAIASQRFEGTTSLGEVRTPGQLSDNNS
                     RQ"
     exon            659..815
                     /gene="Vps26b"
                     /inference="alignment:Splign:2.1.0"
     exon            816..980
                     /gene="Vps26b"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1156
                     /gene="Vps26b"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1299
                     /gene="Vps26b"
                     /inference="alignment:Splign:2.1.0"
     exon            1300..3576
                     /gene="Vps26b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcttgcccc ctcccccgcc tggcgctgcc gtagcacttc ggtgcgttgc gccgcgggag
       61 tctaggcagt tcagtgagtg cggctgggcg ctggacccca cccggtgggc gacgagacgc
      121 gcgtgcttgg cgcctctcct cccggggccc tagtcgctgc accgccagga tctggggagg
      181 tactgtgcct ggcctctcgg tgcaccgctg ctctgtgcac cgcaacccgc agccgaccgc
      241 cttcctccgc cctgcctctc cccaggggcg caggccgtcg gcgatcgccc accgcccagc
      301 tcagaggagc ggggctgcgg tgcggcgtcc agcgcgttcc cgcagccggc cctccggcct
      361 gccttccctg aaggcagccc gagccttgga gggagggagc agtctgtgcc gacaccggcg
      421 cggccaggcg gggagatgag cttcttcggc ttcgggcaga gcgtggaggt ggaaatcttg
      481 ctgaatgatg cggagagtag gaagcgagca gagcacaaga ctgaggacgg gaagaaggag
      541 aaatatttcc tcttctacga cggggaaacc gtctcgggga aggtgagcct atctctgaag
      601 aaccccaaca agcgactaga gcaccagggc atcaagatcg agttcattgg gcaaatcgaa
      661 ctctactatg accgtgggaa ccaccatgag tttgtgtctc tggtgaagga cctggctcgg
      721 ccaggagaga tcacccaatc gcaggccttc gacttcgagt tcacccatgt ggaaaagccg
      781 tatgaatcct acacaggaca gaatgtgaag ctgcgctatt tccttcgagc caccatcagc
      841 cgccgcctca acgacgttgt caaagagatg gacattgtag ttcacacgct tagcacgtac
      901 cccgagctga actcatccat caagatggaa gttggaatcg aggactgcct gcacatcgaa
      961 tttgagtaca acaaatccaa gtaccacttg aaagatgtca ttgtagggaa gatctacttc
     1021 ctgctggtga gaatcaagat caagcacatg gagatagaca tcatcaaacg ggagacaaca
     1081 ggcacgggtc ccaacgtgta ccacgagaac gacacaatag ccaagtatga gatcatggac
     1141 ggggcgccgg tccgaggtga gtccatcccc atcagactct tcctggcagg gtatgagctc
     1201 acgcctacca tgcgggacat aaataagaag ttctctgtgc gctattacct caacttggtg
     1261 ctgatagatg aggaggaacg gcgctacttc aagcagcagg aagtggtgtt gtggcggaag
     1321 ggtgacatcg tacggaagag catgtcccac caggcagcca ttgcctcaca gcgcttcgag
     1381 ggcacaacct ccctgggtga ggtgcggacc cctggccagc tgtctgacaa caacagcagg
     1441 cagtaggccc atggggccaa gaagttgctg ggcttccacc acagaacccc catctaccaa
     1501 ataccagcca ctgggggagg gggaggatgg tgtgaggttc aactggctgt tacttgcaac
     1561 cttggaaaca aatcatgttt tttacttaaa ttcttttctc tgaagaacct aaggggcttg
     1621 ggttgggcag cagtcttcct gggattctgc agcctaggta gggataagga gaggaaacat
     1681 tctggaagct agtctcttcc ttgggaatga gctgtgtgtc aaggctatct caagccttaa
     1741 agcagagttg agagcacaca tccttgactc caggatctct aggcttcctg atacagaagc
     1801 tgagtatgtc cctggcattt acctgccatc aaggctctgg gtaatcatgt cttatactcc
     1861 ccttgactgt tctgaggtag tggcaaaaat ggttgggcct gtctcatcta agttggagga
     1921 agactcaagg tcaggaagct acctctctgg atgtccggga cgtggtgctc tgaagtttct
     1981 acagtcacct ctggcctctc actactggga ccagaccctt ctccatcttc tctagcttgt
     2041 cagaaaatat acaggaacag aagcttaagg aagggtctgg gtctgactat tctctcactt
     2101 gtgagaaaca ggggcacgag aaaccctgat acggtgtcat acatggatgg ctaggagctg
     2161 agctaggtct cctgtagggg aaacatcaga gaaggcaacc gtttgccttc accacatgac
     2221 tccacttggc aacccatcat ctgggttcta gggaattaat ttaagttatc caacaagccc
     2281 taagcagagg atctatttcc tttagcctag atccctacaa gacgctggga tccatctgcc
     2341 tccctaaagc agtccgtcgt tactccttgt cttctgcttg gtttctggaa ctgggcttgg
     2401 tttcaggctt gtagaagttt tgttcttact cccacccata ccctttcatc ccactgttaa
     2461 gggaggacgg gcctctgcac aactatgcta ccatgacttc agagtaattc tgcttgccaa
     2521 attagtctat cttcaccact tcactgacta aagtttagga ccactgtttt gttttgtttt
     2581 gttttgaact taaaaacaaa ataggaaaac tctggtgaat gctggtatac tagagaagaa
     2641 gcagttcttc ctcctgctct gtgcttggcc tgtaagtaga aaagggatga aatgtctttt
     2701 tctaccttgt ctggaaatga ctagaattac catctcctgt tggccgccct cccctgtctg
     2761 agaaagatca agtggacctg atgttcaaca agtacagtat tcactgctct gtgttctttg
     2821 taatttggaa agtaaaggat ttgttcctgt gtcatcttca gttcatgtag aaaatgggga
     2881 ttcttgcaat ctctggcttt gacagggcgg ggctgatgtt taaaagttca gatgaaagac
     2941 tcttggaatg actgaggtta gcgagctaag gaaagtagtt ttctccatgc ctgaccccca
     3001 agtttaggcg tgacatacaa tccccatggg aacaggttca cccatccagc tgtccttggc
     3061 tatcaaggct gggccctagc atatgaagga ggtgggttct gtgcttttgc ccttttcagg
     3121 gtttgacact agactctgct gtgcctcctt taatatctta ttaaaaagca tttgtcaact
     3181 tctctgcctc ccagctgacc acacaaagcc attttccaac tttgctaata tcgtaagcct
     3241 ttcttctggg aaaactagaa ggtagaatat gctgtttctc tcaggagctg tgcacaagcc
     3301 aagtcttgtt ttctctgcct ctgcccccat tctcttttct ctgccaactg tgaaagtatg
     3361 gggaggctcc catccccatc ctttagggtt cccaaacctg gggtgcatag gtactaaacc
     3421 aagcagtgca acctgtaatt aagaagctgc agtgtttcca tgtttcttaa tgtgttgtct
     3481 tttcaatggc tgtattttca aagaacattt gttttaatga tgtctctaat taaaggaagc
     3541 cctatggctt tggaggcatt gtgcccatgc tccacc
//
