LOCUS       NM_001173451            1090 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus vacuolar protein sorting 25 homolog (Vps25),
            mRNA.
ACCESSION   NM_001173451
VERSION     NM_001173451.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1090)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   2  (bases 1 to 1090)
  AUTHORS   Wang,T. and Hong,W.
  TITLE     RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their
            membrane recruitment
  JOURNAL   Biochem Biophys Res Commun 350 (2), 413-423 (2006)
   PUBMED   17010938
REFERENCE   3  (bases 1 to 1090)
  AUTHORS   Langelier,C., von Schwedler,U.K., Fisher,R.D., De Domenico,I.,
            White,P.L., Hill,C.P., Kaplan,J., Ward,D. and Sundquist,W.I.
  TITLE     Human ESCRT-II complex and its role in human immunodeficiency virus
            type 1 release
  JOURNAL   J Virol 80 (19), 9465-9480 (2006)
   PUBMED   16973552
REFERENCE   4  (bases 1 to 1090)
  AUTHORS   Bowers,K., Piper,S.C., Edeling,M.A., Gray,S.R., Owen,D.J.,
            Lehner,P.J. and Luzio,J.P.
  TITLE     Degradation of endocytosed epidermal growth factor and virally
            ubiquitinated major histocompatibility complex class I is
            independent of mammalian ESCRTII
  JOURNAL   J Biol Chem 281 (8), 5094-5105 (2006)
   PUBMED   16371348
REFERENCE   5  (bases 1 to 1090)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   6  (bases 1 to 1090)
  AUTHORS   Martin-Serrano,J., Yarovoy,A., Perez-Caballero,D. and Bieniasz,P.D.
  TITLE     Divergent retroviral late-budding domains recruit vacuolar protein
            sorting factors by using alternative adaptor proteins
  JOURNAL   Proc Natl Acad Sci U S A 100 (21), 12414-12419 (2003)
   PUBMED   14519844
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):152845.
            Yaravoy, A [corrected to Yarovoy, A]]
REFERENCE   7  (bases 1 to 1090)
  AUTHORS   Kamura,T., Burian,D., Khalili,H., Schmidt,S.L., Sato,S., Liu,W.J.,
            Conrad,M.N., Conaway,R.C., Conaway,J.W. and Shilatifard,A.
  TITLE     Cloning and characterization of ELL-associated proteins EAP45 and
            EAP20. a role for yeast EAP-like proteins in regulation of gene
            expression by glucose
  JOURNAL   J Biol Chem 276 (19), 16528-16533 (2001)
   PUBMED   11278625
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ220187.1, FQ213477.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                JAXUCZ010000010.1  86696387-86696465
            80-225              JAXUCZ010000010.1  86696688-86696833
            226-279             JAXUCZ010000010.1  86697596-86697649
            280-368             JAXUCZ010000010.1  86698525-86698613
            369-444             JAXUCZ010000010.1  86699399-86699474
            445-1090            JAXUCZ010000010.1  86701226-86701871
FEATURES             Location/Qualifiers
     source          1..1090
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..1090
                     /gene="Vps25"
                     /note="vacuolar protein sorting 25 homolog"
                     /db_xref="GeneID:681059"
                     /db_xref="RGD:1584685"
     exon            1..79
                     /gene="Vps25"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..557
                     /gene="Vps25"
                     /note="ESCRT-II complex subunit VPS25; ELL-associated
                     protein of 20 kDa"
                     /codon_start=1
                     /product="vacuolar protein-sorting-associated protein 25"
                     /protein_id="NP_001166922.1"
                     /db_xref="GeneID:681059"
                     /db_xref="RGD:1584685"
                     /translation="MAMSFEWPWQYRFPPFFTLQPNVDTRQKQLAAWCSLVLSFCRLH
                     KQSSMTVMEAQESPLFNNVKLQRKLPVESIQIVLEELRKKGNLEWLDKNKSSFLIMWR
                     RPEEWGKLIYQWVSRSGQNNSVFTLYELTSGEDTEEEEFHGLDEATLLRALQALQQEH
                     KAEIITVSDGRGVKFF"
     exon            80..225
                     /gene="Vps25"
                     /inference="alignment:Splign:2.1.0"
     exon            226..279
                     /gene="Vps25"
                     /inference="alignment:Splign:2.1.0"
     exon            280..368
                     /gene="Vps25"
                     /inference="alignment:Splign:2.1.0"
     exon            369..444
                     /gene="Vps25"
                     /inference="alignment:Splign:2.1.0"
     exon            445..1090
                     /gene="Vps25"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggttccgggt tttgtgggct actacgatgg cgatgagttt cgagtggccg tggcagtacc
       61 gcttcccgcc cttctttacg ttacagccga acgtggacac ccggcagaag cagctggccg
      121 cctggtgctc tctggttctg tccttctgcc gcctgcacaa acagtccagc atgacggtga
      181 tggaagccca ggagagcccg ctcttcaaca acgtcaagct acagcggaaa cttcctgtgg
      241 agtcgattca gattgtatta gaagaactga ggaagaaagg gaacctcgag tggttggata
      301 agaataagtc tagcttcctg atcatgtggc ggaggccaga agaatggggg aaactcattt
      361 atcaatgggt ttccaggagt ggccagaata actctgtgtt caccctgtat gaactgacca
      421 gtggggaaga cacagaggag gaagagttcc atgggctgga tgaggcgacc ctgctgcgtg
      481 ctctgcaggc cctacagcag gagcacaagg ctgagattat cactgtcagc gatggccgag
      541 gagtcaaatt cttctagcag agacctgtct ccctttactt cttacctccc acctttccag
      601 ggctttcaaa aggagacaga cctagtgtcc ccacagactg gatctgtcac tccaccagac
      661 tcaaagggct caagtcctga aagctcagac ttagggatgt ttcccacata acctgttcta
      721 tctgtccctg ggatagggta gcccacagtg ccatggagaa aggatgtgtt gcctgcccta
      781 cctcctttcc tatcctgtac tgtccctgag ctagggtcta taaacctgac actttacatg
      841 tgttctcaca cataagtaca cacccaccta catgcgcctg cacaagcttc tttctcctcc
      901 tcctcctccc actcctgtag ctgctgttgc ctcccttctc aggctggtgc tggatccttc
      961 ctagggatgg gggaagccct ggctgcaggc agccttccag gcaatataaa gataggaagc
     1021 cccagaaggg gcctggcagt gagaggcagg cccactgatt tatgatatta aaatctctac
     1081 tcccactgtc
//
