LOCUS       NM_001108845             791 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus V-set pre-B cell surrogate light chain 1A
            (Vpreb1a), mRNA.
ACCESSION   NM_001108845
VERSION     NM_001108845.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Erlandsson L, Licence S, Gaspal F, Lane P, Corcoran AE and
            Martensson IL.
  TITLE     Both the pre-BCR and the IL-7Ralpha are essential for expansion at
            the pre-BII cell stage in vivo
  JOURNAL   Eur J Immunol 35 (6), 1969-1976 (2005)
   PUBMED   15909309
REFERENCE   2  (bases 1 to 791)
  AUTHORS   Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M,
            Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail
            S, Li P and Sutton G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   3  (bases 1 to 791)
  AUTHORS   Shimizu T, Mundt C, Licence S, Melchers F and Martensson IL.
  TITLE     VpreB1/VpreB2/lambda 5 triple-deficient mice show impaired B cell
            development but functional allelic exclusion of the IgH locus
  JOURNAL   J Immunol 168 (12), 6286-6293 (2002)
   PUBMED   12055243
REFERENCE   4  (bases 1 to 791)
  AUTHORS   Martensson A, Argon Y, Melchers F, Dul JL and Martensson IL.
  TITLE     Partial block in B lymphocyte development at the transition into
            the pre-B cell receptor stage in Vpre-B1-deficient mice
  JOURNAL   Int Immunol 11 (3), 453-460 (1999)
   PUBMED   10221657
REFERENCE   5  (bases 1 to 791)
  AUTHORS   Dul JL, Argon Y, Winkler T, ten Boekel E, Melchers F and Martensson
            IL.
  TITLE     The murine VpreB1 and VpreB2 genes both encode a protein of the
            surrogate light chain and are co-expressed during B cell
            development
  JOURNAL   Eur J Immunol 26 (4), 906-913 (1996)
   PUBMED   8625987
REFERENCE   6  (bases 1 to 791)
  AUTHORS   Hasegawa M and Ebihara S.
  TITLE     Circadian rhythms of pineal melatonin release in the pigeon
            measured by in vivo microdialysis
  JOURNAL   Neurosci Lett 148 (1-2), 89-92 (1992)
   PUBMED   1300510
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473999.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_577195.2, XM_001062818.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN06621351,
                              SAMN06680412 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q23"
     gene            1..791
                     /gene="Vpreb1a"
                     /gene_synonym="Vpreb1"
                     /note="V-set pre-B cell surrogate light chain 1A"
                     /db_xref="GeneID:303782"
                     /db_xref="RGD:1588558"
     exon            1..170
                     /gene="Vpreb1a"
                     /gene_synonym="Vpreb1"
                     /inference="alignment:Splign:2.1.0"
     CDS             125..535
                     /gene="Vpreb1a"
                     /gene_synonym="Vpreb1"
                     /note="pre-B lymphocyte gene 1; Immunoglobulin lambda
                     Vpreb1 chain; immunoglobulin iota chain; immunoglobulin
                     omega chain-like; pre-B lymphocyte 1; V-set pre-B cell
                     surrogate light chain 1"
                     /codon_start=1
                     /product="immunoglobulin iota chain precursor"
                     /protein_id="NP_001102315.1"
                     /db_xref="GeneID:303782"
                     /db_xref="RGD:1588558"
                     /translation="MAWTSALLILLAHLTGCGPQPVLHQPPSASSFLGTSIRLTCALS
                     SNHNIGIYSIYWYQQRPGHPPTFLLRFFSHSDKLQGPKIPPRFSGSKDTARNLGYLSI
                     SDLQPEDEAVYYCAVGLRSWEKEKRMEREWEEEK"
     exon            171..791
                     /gene="Vpreb1a"
                     /gene_synonym="Vpreb1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccagaaagcc tgggagggtg gtgagcagga accagtggtg caaagcaggg gcgagactgc
       61 ttcctagctg gtcagggcac cggagcagtg gctgtagggg tcagggtgct gcaggtctgg
      121 aaccatggcc tggacgtctg ccctgctcat actgctggcc catctcacag gttgtggccc
      181 tcagcccgtg ctgcatcagc caccatcggc ctcttccttc cttggaacct ccatccgcct
      241 cacctgtgcc ctgagcagca accataacat tggcatttac agcatttact ggtaccagca
      301 gaggccgggc caccctccca cgttcctgct gagattcttc tcacactcag acaagctcca
      361 gggtcccaag atcccccctc gcttctccgg atccaaagat acagccagga acctggggta
      421 cctgagcatc tctgacctgc agccagagga cgaggctgtg tattactgcg ccgtggggct
      481 tcggagctgg gaaaaggaga agaggatgga gagggagtgg gaagaagaaa agtagcggac
      541 agattcggga tcttaggctc tggagacatt cagacctaga accgaagacg gagtttgctt
      601 tgctcggcta ggctggtttg gggaggaggg gtagaacacc gggcttcgca gagccaggaa
      661 ggtggagcca gccgcttttc cttgtattgc agtgttgcta tgcgccccat cggaggctgg
      721 attgtagaat taaagctgtt tttttttttt ttgttttgtt tttttgtttt ttgtttcttt
      781 tttcttaact g
//
