LOCUS       NP_001102606             500 aa            linear   ROD 22-MAR-2023
DEFINITION  vascular non-inflammatory molecule 3 precursor [Rattus norvegicus].
ACCESSION   NP_001102606 XP_001055514 XP_574282
VERSION     NP_001102606.1
DBSOURCE    REFSEQ: accession NM_001109136.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 500)
  AUTHORS   Martin F, Malergue F, Pitari G, Philippe JM, Philips S, Chabret C,
            Granjeaud S, Mattei MG, Mungall AJ, Naquet P and Galland F.
  TITLE     Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and
            encode isoforms of pantetheinase ectoenzymes
  JOURNAL   Immunogenetics 53 (4), 296-306 (2001)
   PUBMED   11491533
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474002.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_001055514.1, XP_574282.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760494
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p12"
     Protein         1..500
                     /product="vascular non-inflammatory molecule 3 precursor"
                     /EC_number="3.5.1.-"
                     /note="vascular non-inflammatory molecule 3"
                     /calculated_mol_wt=54063
     sig_peptide     1..22
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
                     /calculated_mol_wt=2377
     Region          26..310
                     /region_name="biotinidase_like"
                     /note="biotinidase and vanins (class 4 nitrilases);
                     cd07567"
                     /db_xref="CDD:143591"
     Site            order(80,179,183,186,212..213,215..216,238)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:143591"
     Site            order(80,179,212)
                     /site_type="active"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:143591"
     Site            order(180..183,185,192..194,213,215..219,222..223,
                     244..245,247..249,251..252,276..277)
                     /site_type="other"
                     /note="putative dimer interface [polypeptide binding]"
                     /db_xref="CDD:143591"
     Region          337..488
                     /region_name="Vanin_C"
                     /note="Vanin C-terminal domain; pfam19018"
                     /db_xref="CDD:465946"
     CDS             1..500
                     /gene="Vnn3"
                     /gene_synonym="RGD1560609"
                     /coded_by="NM_001109136.1:118..1620"
                     /db_xref="GeneID:498992"
                     /db_xref="RGD:1560609"
ORIGIN      
        1 mvslyfpqcv vsfvlfaqav gamdtfiaav yehavilpnk tespvsneea lllinknidi
       61 lenaiklaar qgahiivtpe dgiygwiftr etiypyledi pdpevnwipc rdpkrfgftp
      121 vqerlsclak ensiyivani gdkkpcnttd pqcprdgryq yntnvvfdse grltaryhky
      181 nlfepeiqfd fpkdselvtf dtpfgkfgvf tcfdifsydp avmvvkdsrv dsvllptawy
      241 ntlpllsavp fhsawaramg vnvlaanthn trmhmtgsgi yspdavrvyy ydmetengql
      301 llselrsrpr qhgfpaevdw sayartvkpf sseqadfqgt iyfdefsftk lmgsagnytv
      361 cqkdlcchlt ykmsesrmde ayvlgafdgl htvegqyylq ictllkcqtt nlrtcgepvg
      421 saftkfeefs lsgtfgtkyv fpqivlsgsq laleryyevs rdgrlrsrgg aplpvlvmal
      481 ygrvferdpp rlgqgpgkvq
//
