LOCUS       NM_031140               1796 bp    mRNA    linear   ROD 17-MAR-2024
DEFINITION  Rattus norvegicus vimentin (Vim), mRNA.
ACCESSION   NM_031140
VERSION     NM_031140.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1796)
  AUTHORS   Zholudeva,A.O., Potapov,N.S., Kozlova,E.A., Lomakina,M.E. and
            Alexandrova,A.Y.
  TITLE     Impairment of Assembly of the Vimentin Intermediate Filaments Leads
            to Suppression of Formation and Maturation of Focal Contacts and
            Alteration of the Type of Cellular Protrusions
  JOURNAL   Biochemistry (Mosc) 89 (1), 184-195 (2024)
   PUBMED   38467554
  REMARK    GeneRIF: Impairment of Assembly of the Vimentin Intermediate
            Filaments Leads to Suppression of Formation and Maturation of Focal
            Contacts and Alteration of the Type of Cellular Protrusions.
REFERENCE   2  (bases 1 to 1796)
  AUTHORS   Coelho,N.R., Tomkiewicz,C., Correia,M.J., Goncalves-Dias,C.,
            Barouki,R., Pereira,S.A., Coumoul,X. and Monteiro,E.C.
  TITLE     First evidence of aryl hydrocarbon receptor as a druggable target
            in hypertension induced by chronic intermittent hypoxia
  JOURNAL   Pharmacol Res 159, 104869 (2020)
   PUBMED   32416216
REFERENCE   3  (bases 1 to 1796)
  AUTHORS   Liang,J.R. and Yang,H.
  TITLE     Ginkgolic acid (GA) suppresses gastric cancer growth by inducing
            apoptosis and suppressing STAT3/JAK2 signaling regulated by ROS
  JOURNAL   Biomed Pharmacother 125, 109585 (2020)
   PUBMED   32106377
REFERENCE   4  (bases 1 to 1796)
  AUTHORS   Vakhrusheva,A., Endzhievskaya,S., Zhuikov,V., Nekrasova,T.,
            Parshina,E., Ovsiannikova,N., Popov,V., Bagrov,D., Minin
            Acapital,A. Cyrillic and Sokolova,O.S.
  TITLE     The role of vimentin in directional migration of rat fibroblasts
  JOURNAL   Cytoskeleton (Hoboken) 76 (9-10), 467-476 (2019)
   PUBMED   31626376
  REMARK    GeneRIF: The role of vimentin in directional migration of rat
            fibroblasts.
REFERENCE   5  (bases 1 to 1796)
  AUTHORS   Zhu,W.B., Zhao,Z.F. and Zhou,X.
  TITLE     AMD3100 inhibits epithelial-mesenchymal transition, cell invasion,
            and metastasis in the liver and the lung through blocking the
            SDF-1alpha/CXCR4 signaling pathway in prostate cancer
  JOURNAL   J Cell Physiol 234 (7), 11746-11759 (2019)
   PUBMED   30537000
REFERENCE   6  (bases 1 to 1796)
  AUTHORS   Bussemakers,M.J., Verhaegh,G.W., van Bokhoven,A., Debruyne,F.M. and
            Schalken,J.A.
  TITLE     Differential expression of vimentin in rat prostatic tumors
  JOURNAL   Biochem Biophys Res Commun 182 (3), 1254-1259 (1992)
   PUBMED   1540169
REFERENCE   7  (bases 1 to 1796)
  AUTHORS   Bussemakers,M.J., van Bokhoven,A., van Groningen,J.J.,
            Debruyne,F.M. and Schalken,J.A.
  TITLE     Increased expression of retroviral sequences in progressionally
            advanced rat prostatic tumors
  JOURNAL   Biochem Biophys Res Commun 182 (1), 318-324 (1992)
   PUBMED   1370615
REFERENCE   8  (bases 1 to 1796)
  AUTHORS   Monteiro,M.J. and Cleveland,D.W.
  TITLE     Expression of NF-L and NF-M in fibroblasts reveals coassembly of
            neurofilament and vimentin subunits
  JOURNAL   J Cell Biol 108 (2), 579-593 (1989)
   PUBMED   2493000
REFERENCE   9  (bases 1 to 1796)
  AUTHORS   Akoglu,T., Kozakoglu,H. and Akoglu,E.
  TITLE     Antibody to intermediate filaments of the cytoskeleton in patients
            with Behcet's disease
  JOURNAL   Clin Immunol Immunopathol 41 (3), 427-432 (1986)
   PUBMED   3780056
REFERENCE   10 (bases 1 to 1796)
  AUTHORS   Kurki,P., Helve,T. and Virtanen,I.
  TITLE     Antibodies to cytoplasmic intermediate filaments in rheumatic
            diseases
  JOURNAL   J Rheumatol 10 (4), 558-562 (1983)
   PUBMED   6352937
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X62952.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X62952.1, BC061847.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1796
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Fischer Copenhagen"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.3"
     gene            1..1796
                     /gene="Vim"
                     /note="vimentin"
                     /db_xref="GeneID:81818"
                     /db_xref="RGD:621646"
     exon            1..643
                     /gene="Vim"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..1481
                     /gene="Vim"
                     /codon_start=1
                     /product="vimentin"
                     /protein_id="NP_112402.1"
                     /db_xref="GeneID:81818"
                     /db_xref="RGD:621646"
                     /translation="MSTRSVSSSSYRRMFGGSGTSSRPSSNRSYVTTSTRTYSLGSAL
                     RPSTSRSLYSSSPGGAYVTRSSAVRLRSSMPGVRLLQDSVDFSLADAINTEFKNTRTN
                     EKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQ
                     VDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAESTLQSFRQDVDNASLARL
                     DLERKVESLQEEIAFLKKLHDEEIQELQAQIQEQHVQIDVDVSKPDLTAALRDVRQQY
                     ESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESNEYRRQVQSLTCEVDALK
                     GTNESLERQMREMEENFALEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMA
                     LDIEIATYRKLLEGEESRISLPLPNFSSLNLRETNLESLPLVDTHSKRTLLIKTVETR
                     DGQVINETSQHHDDLE"
     exon            644..704
                     /gene="Vim"
                     /inference="alignment:Splign:2.1.0"
     exon            705..800
                     /gene="Vim"
                     /inference="alignment:Splign:2.1.0"
     exon            801..962
                     /gene="Vim"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1088
                     /gene="Vim"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1309
                     /gene="Vim"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1353
                     /gene="Vim"
                     /inference="alignment:Splign:2.1.0"
     exon            1354..1439
                     /gene="Vim"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1796
                     /gene="Vim"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttcacagcc actgcgccct cgctctcttc ttgcagatct tgcagccgca gcaagccagg
       61 ccacctcgtc cttcgaagcc atgtccacca ggtccgtgtc ctcgtcctcc taccgcagga
      121 tgttcggtgg ctccggcaca tcgagccggc ccagctccaa ccggagctat gtgaccacat
      181 ccacccgcac ctacagccta ggcagcgcgc tgcgccccag cactagccgc agcctctatt
      241 cctcgtcccc gggtggcgcc tatgtgaccc ggtcctccgc cgtgcgcctg cggagcagca
      301 tgcccggcgt gcggctgctg caggactccg tggacttctc gctggccgac gccatcaaca
      361 ccgagttcaa gaacacccgc accaacgaga aggtggaatt gcaggagctg aatgaccgct
      421 tcgccaacta catcgacaag gtgcgcttcc tcgagcagca gaacaaaatc ctgctggccg
      481 agctcgagca gcttaagggc cagggcaagt cgcgcctggg cgacctctac gaggaggaga
      541 tgagggagtt gcgccggcag gtggatcagc tcaccaatga caaggcccgt gtcgaggtgg
      601 agagggacaa cctggccgag gacatcatgc ggctgcgaga aaaattgcag gaggagatgc
      661 tccagaggga ggaagccgag agcaccctgc agtcattcag acaggatgtt gacaatgctt
      721 ctctggcacg tcttgacctt gaacgtaaag tggaatcctt gcaggaagaa attgcctttt
      781 tgaagaagct gcacgatgaa gagatccagg agctgcaggc ccagattcag gaacagcatg
      841 tccagatcga tgtggacgtt tccaagcctg acctcaccgc tgccctgcgt gatgtccgcc
      901 agcagtatga aagtgtggct gccaagaacc tccaggaggc cgaggaatgg tacaagtcca
      961 agtttgctga cctctctgag gctgccaacc ggaacaacga tgccctgcgc caggcaaagc
     1021 aggagtcaaa cgaataccgg agacaggtgc agtcactcac ctgcgaagtg gatgccctta
     1081 aaggcactaa tgagtccctg gagcgccaga tgcgtgaaat ggaagagaat tttgcccttg
     1141 aagctgctaa ctaccaggac actattggcc gcctgcagga tgagatccag aacatgaagg
     1201 aagagatggc tcgccacctt cgtgaatacc aggacctgct caatgtaaag atggctcttg
     1261 acattgagat cgccacctac aggaagctgc tggaagggga ggagagcagg atttctctgc
     1321 ctcttccaaa cttttcttcc ctgaacctga gagaaactaa cctggagtca cttcctctgg
     1381 ttgacaccca ctccaaaaga acactcctga ttaagacggt tgaaaccaga gacggacagg
     1441 tgatcaatga gacttctcag caccacgatg accttgaata aaaactgcac aggctcagtg
     1501 caacggcgca gtaccagcaa gaaggaaaaa aaaatcgtat cttagaaaaa agagctttca
     1561 agtgccttta ctgcagtttt caggagcgca agatagatct gggatagaaa cgagctcagc
     1621 acataacaac tgacaccccc aaaaggcgta gaaaaggttt acaaaataat ctagttttac
     1681 gaagaaatct tgtgctagaa tactttttaa agtatttttg aataccatta aaactgcttt
     1741 ctttttccag aaaatatctg accaacttgt tactgcttca ataaaacttc agaaat
//
