LOCUS       NM_001014171            3068 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus ventricular zone expressed PH domain-containing 1
            (Veph1), mRNA.
ACCESSION   NM_001014171 XM_342256
VERSION     NM_001014171.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3068)
  AUTHORS   Shathasivam,P., Kollara,A., Ringuette,M.J., Virtanen,C., Wrana,J.L.
            and Brown,T.J.
  TITLE     Human ortholog of Drosophila Melted impedes SMAD2 release from
            TGF-beta receptor I to inhibit TGF-beta signaling
  JOURNAL   Proc Natl Acad Sci U S A 112 (23), E3000-E3009 (2015)
   PUBMED   26039994
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC087055.1.
            
            On Apr 20, 2005 this sequence version replaced XM_342256.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087055.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5756307,
                                           SAMEA5760383 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3068
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q31"
     gene            1..3068
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /note="ventricular zone expressed PH domain-containing 1"
                     /db_xref="GeneID:361954"
                     /db_xref="RGD:1308217"
     exon            1..73
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
     exon            74..358
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
     CDS             221..2719
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /note="protein melted homolog; ventricular zone expressed
                     PH domain homolog 1"
                     /codon_start=1
                     /product="ventricular zone-expressed PH domain-containing
                     protein homolog 1"
                     /protein_id="NP_001014193.1"
                     /db_xref="GeneID:361954"
                     /db_xref="RGD:1308217"
                     /translation="MHQLFRLVLGQKDLSRAGDLFSLDDAEIEDSLTEALEQIKVISS
                     SLDYQTNNNDQAVVEICITRITTAIRETESIEKHARALVGLWDSCLEHNLRPAGKDED
                     TPHAKIASDIMSCILQNYNRTPVMVLAVPIAVKFLHRGSKELCRNMSNYLSLAAITKA
                     DLLADHTEGIVKSILQGNAMLLRVLPAVYEKQPQPINRHLAELLALMSQLEQTEQYHL
                     LRLLHVAAKRKDVEVVQKCVPFLIRNLKESTYNDIILNILIEIAGHEPLALNSFLPML
                     KEIAEQFPYLTGQMARIFGAVGHVDEERARSCLRYLVSQLANMEHSFHHILLLEIKSL
                     TDAFSSILGPHSRDIFRMSNSFTNIAKLLSRQLENSKAESGRRRTGTEVSFPEKFREP
                     KTMEPKSEDHEKLQVKIQAFEDKINAESHTPGSVRRYSLDHVSKEERKNVRFSRSRSL
                     ALNTVLTNSVNVEDGEIEGKTGMHASISLSEIDPPGHGIGKVPFKTDTHGSQLRNSSA
                     SHPSIIHSEPENMPETFKENVQEEIPEAAISPVEYQDKLYLHLKENLSKVKAYALEIA
                     KKVPIPDQCTIEDNTRSCVAKLFFTCSLKGHYCLYSKSSFTLVSQAPQPWIQIMFLFQ
                     QSLFPEPLSIQSGSVQFLKALWEKTQGTGTHSFEVAMTESTFPQQKDLDQLQLHLEEV
                     RFFDVFGFSETAGAWQCFMCNNPEKATVINQDGQPLIEGKLKEKQVRWKFIKRWKTRY
                     FTLAGNQLLFQKGKSDDPDDSPIELSKVQSVKAVAKKRRDRSLPRAFEIFTDNKTYVF
                     KAKDEKNAEEWLQCINVALAQAKERESREVTTYL"
     exon            359..574
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
     exon            575..749
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
     exon            750..916
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1126
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1347
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
     exon            1348..1557
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
     exon            1558..1955
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
     exon            1956..2095
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
     exon            2096..2230
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
     exon            2231..2348
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
     exon            2349..2485
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
     exon            2486..3009
                     /gene="Veph1"
                     /gene_synonym="RGD1308217"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccagctgaa gtgttcgaag aatcaagcat ttgccttctg ttgcctgcac ctgccagtgt
       61 cccgtgctag gagagactgc caaaggagac cttagggcct gaagaactat ggctcttcat
      121 ggaatataag tgtaccaact gctacatggt tttctatctc taaccctgga taacagagca
      181 tggccccgga gctacagaaa gccaactgat ccaactcaca atgcaccaac ttttcagatt
      241 ggttttggga caaaaagatc tttcaagagc tggggacctc ttctctttag atgacgctga
      301 gatagaagac agcctgacag aagctttgga gcagattaaa gtaattagct catctttgga
      361 ttatcaaact aataacaatg accaggcagt ggttgaaatc tgtatcacga ggattacaac
      421 agccatcaga gagacggaat ccattgaaaa gcacgccagg gccctggtgg gactgtggga
      481 ttcctgcttg gagcacaacc tgagacctgc agggaaagac gaagatactc cacacgctaa
      541 aatcgcatcc gatatcatga gttgtatctt acaaaattac aaccggaccc ctgtgatggt
      601 cttagctgta cccatcgcag tgaaattcct ccacagaggc agcaaggagc tgtgtaggaa
      661 catgtccaac tacctgtcct tggctgccat caccaaggcc gatctcctgg ctgaccacac
      721 tgaagggata gtaaagagca tactccaagg aaatgccatg ctactgaggg tgttgcctgc
      781 tgtgtatgaa aagcagcccc aaccaatcaa caggcacctg gcagaactcc tggccttgat
      841 gtctcaattg gagcagacag aacagtacca tctactacgg cttctccatg tagcagcaaa
      901 gagaaaagat gtggaggtgg ttcagaaatg tgttcctttc ctgatcagaa acctgaagga
      961 gtcaacctat aatgacatca tcctgaacat cctcatagaa atagcaggcc atgagccgct
     1021 ggccttgaac agttttctcc caatgctgaa agagattgca gagcaattcc cctacctcac
     1081 tggacaaatg gcgaggatct ttggtgctgt tgggcatgtg gatgaagaga gagccaggag
     1141 ctgcctacgg tacctggtga gccagctggc taacatggag cattcattcc accacattct
     1201 cctgctggaa attaagagtc tcacagatgc cttctcctcc attctgggcc ctcacagcag
     1261 ggacatcttc cgaatgagca acagcttcac caacatcgcc aagctgcttt cccgacaact
     1321 ggaaaacagc aaggccgaga gtggcaggag aagaaccggc actgaagtta gctttcctga
     1381 gaaattcaga gaacccaaga ccatggagcc taaaagtgaa gaccacgaaa aactccaagt
     1441 taaaatccag gccttcgaag ataaaataaa tgctgagagc catacccctg gctctgtccg
     1501 gagatacagt ttagaccacg tctccaagga agaacgaaaa aacgttcgat ttagcaggtc
     1561 cagaagtttg gctttgaata ctgtgctcac aaacagtgtg aatgtggaag acggagaaat
     1621 cgaaggaaag acaggaatgc atgccagcat ctcgctttca gaaatagacc cacctggcca
     1681 cggaattggc aaggtgccct ttaagacgga tacccatgga tcacagctga gaaattcctc
     1741 agcttcacac ccaagtatta tacacagtga accagaaaat atgcctgaaa cttttaaaga
     1801 aaacgtccaa gaagaaattc cagaggcggc cataagtcct gtggaatacc aagataagct
     1861 ctacttacac ttaaaggaaa acctcagcaa agtgaaggca tacgccttgg aaatcgcaaa
     1921 aaaagtccca atcccagacc agtgcaccat tgaagataat acgagaagct gtgtggcaaa
     1981 gctgttcttt acgtgttcgt taaagggtca ttactgccta tacagcaagt ccagtttcac
     2041 ccttgtcagc caagcccccc agccatggat tcagatcatg tttctcttcc aacagagcct
     2101 gtttcctgag cccctgtcca ttcagagtgg ctcggtgcag ttcctcaagg ccctatggga
     2161 gaagacacag ggcacaggaa cccacagctt tgaggtcgcc atgacagagt ccacatttcc
     2221 acagcagaag gatctggacc agcttcagct ccatctggaa gaagtgcggt tctttgatgt
     2281 gtttggcttc agcgaaacag caggggcatg gcaatgcttc atgtgtaaca accccgaaaa
     2341 ggcaactgtt ataaatcaag atggccagcc tctcattgaa ggaaagctta aggagaaaca
     2401 agtgaggtgg aagttcatca agaggtggaa aacacgttat tttacactgg ctggaaacca
     2461 acttctgttt caaaagggga aatctgacga ccccgatgat tccccgatag aactcagcaa
     2521 agtacagagc gtgaaagctg tggccaagaa gcgtcgggac cgctctctcc ctcgggcttt
     2581 tgaaatcttc acagacaata agacctatgt tttcaaagcc aaggatgaga aaaacgcaga
     2641 ggagtggctg cagtgcatca acgtggcgct ggcccaggca aaggagaggg agagccgaga
     2701 agtaaccaca tatctgtagg gattcgtaca cccgctctta tggccactca agacaggcat
     2761 tgttagtgtc aacaaagaac ccaccatggc actattgggt ttcactaaat accagggaaa
     2821 ccattaaccc taaggagagc ctaaaatggc agggttctca gtaaacccct tgccctcaca
     2881 gatcttgtat taactccaag atttctgcct gaagacatgg gaaagagaaa ccatggagat
     2941 catattgaat ggagcacata ggtcaggaat ggaaagttaa cgaataaaag aacttctgta
     3001 gctatgtgaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     3061 aaaaaaaa
//
