LOCUS       NM_031355               1361 bp    mRNA    linear   ROD 16-FEB-2025
DEFINITION  Rattus norvegicus voltage-dependent anion channel 3 (Vdac3), mRNA.
ACCESSION   NM_031355
VERSION     NM_031355.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1361)
  AUTHORS   Ha,S.D., Park,S., Han,C.Y., Nguyen,M.L. and Kim,S.O.
  TITLE     Cellular adaptation to anthrax lethal toxin-induced mitochondrial
            cholesterol enrichment, hyperpolarization, and reactive oxygen
            species generation through downregulating MLN64 in macrophages
  JOURNAL   Mol Cell Biol 32 (23), 4846-4860 (2012)
   PUBMED   23028046
REFERENCE   2  (bases 1 to 1361)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 1361)
  AUTHORS   Zhao,X., Leon,I.R., Bak,S., Mogensen,M., Wrzesinski,K., Hojlund,K.
            and Jensen,O.N.
  TITLE     Phosphoproteome analysis of functional mitochondria isolated from
            resting human muscle reveals extensive phosphorylation of inner
            membrane protein complexes and enzymes
  JOURNAL   Mol Cell Proteomics 10 (1), M110.000299 (2011)
   PUBMED   20833797
REFERENCE   4  (bases 1 to 1361)
  AUTHORS   Morciano,M., Beckhaus,T., Karas,M., Zimmermann,H. and Volknandt,W.
  TITLE     The proteome of the presynaptic active zone: from docked synaptic
            vesicles to adhesion molecules and maxi-channels
  JOURNAL   J Neurochem 108 (3), 662-675 (2009)
   PUBMED   19187093
REFERENCE   5  (bases 1 to 1361)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 1361)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   7  (bases 1 to 1361)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   8  (bases 1 to 1361)
  AUTHORS   Weeber,E.J., Levy,M., Sampson,M.J., Anflous,K., Armstrong,D.L.,
            Brown,S.E., Sweatt,J.D. and Craigen,W.J.
  TITLE     The role of mitochondrial porins and the permeability transition
            pore in learning and synaptic plasticity
  JOURNAL   J Biol Chem 277 (21), 18891-18897 (2002)
   PUBMED   11907043
REFERENCE   9  (bases 1 to 1361)
  AUTHORS   Shinohara,Y., Ishida,T., Hino,M., Yamazaki,N., Baba,Y. and
            Terada,H.
  TITLE     Characterization of porin isoforms expressed in tumor cells
  JOURNAL   Eur J Biochem 267 (19), 6067-6073 (2000)
   PUBMED   10998068
REFERENCE   10 (bases 1 to 1361)
  AUTHORS   Anflous,K., Blondel,O., Bernard,A., Khrestchatisky,M. and
            Ventura-Clapier,R.
  TITLE     Characterization of rat porin isoforms: cloning of a cardiac type-3
            variant encoding an additional methionine at its putative
            N-terminal region
  JOURNAL   Biochim Biophys Acta 1399 (1), 47-50 (1998)
   PUBMED   9714728
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On Nov 26, 2020 this sequence version replaced NM_031355.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB039664.1, BC061780.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-87                JAXUCZ010000016.1  76137489-76137575
            88-156              JAXUCZ010000016.1  76142065-76142133
            157-206             JAXUCZ010000016.1  76143216-76143265
            207-359             JAXUCZ010000016.1  76147053-76147205
            360-412             JAXUCZ010000016.1  76148653-76148705
            413-640             JAXUCZ010000016.1  76150536-76150763
            641-791             JAXUCZ010000016.1  76151906-76152056
            792-849             JAXUCZ010000016.1  76152931-76152988
            850-1361            JAXUCZ010000016.1  76153422-76153933
FEATURES             Location/Qualifiers
     source          1..1361
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.5"
     gene            1..1361
                     /gene="Vdac3"
                     /note="voltage-dependent anion channel 3"
                     /db_xref="GeneID:83532"
                     /db_xref="RGD:621577"
     exon            1..87
                     /gene="Vdac3"
                     /inference="alignment:Splign:2.1.0"
     exon            88..156
                     /gene="Vdac3"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..941
                     /gene="Vdac3"
                     /note="voltage-dependent anion-selective channel protein
                     3; VDAC-3; rVDAC3; outer mitochondrial membrane protein
                     porin 3; mitochondrial voltage dependent anion channel 3"
                     /codon_start=1
                     /product="non-selective voltage-gated ion channel VDAC3"
                     /protein_id="NP_112645.2"
                     /db_xref="GeneID:83532"
                     /db_xref="RGD:621577"
                     /translation="MCSTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTS
                     GHAYTDTGKASGNLETKYKVCNYGLIFTQKWNTDNTLGTEISWENKLAEGLKLTVDTI
                     FVPNTGKKSGKLKASYRRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTA
                     KSKLCQNNFALGYKAEDFQLHTHVNDGTEFGGSIYQRVNEKIETSINLAWTAGSNNTR
                     FGIAAKYRLDCRTSLSAKVNNASLIGLGYTQSLRPGVKLTLSALVDGKNFNAGGHKVG
                     LGFELEA"
     exon            157..206
                     /gene="Vdac3"
                     /inference="alignment:Splign:2.1.0"
     exon            207..359
                     /gene="Vdac3"
                     /inference="alignment:Splign:2.1.0"
     exon            360..412
                     /gene="Vdac3"
                     /inference="alignment:Splign:2.1.0"
     exon            413..640
                     /gene="Vdac3"
                     /inference="alignment:Splign:2.1.0"
     exon            641..791
                     /gene="Vdac3"
                     /inference="alignment:Splign:2.1.0"
     exon            792..849
                     /gene="Vdac3"
                     /inference="alignment:Splign:2.1.0"
     exon            850..1361
                     /gene="Vdac3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggtcgcgca ggcgcagacg gcgttggttc gagaagacct tcagcgttgc cttggtggag
       61 cgggacgggc ccaccctcgg gttgtagata tgtgtagcac accaacttac tgcgacctag
      121 gaaaggctgc caaggatgtc tttaacaaag ggtatgggtt tggcatggtc aaaatagatc
      181 tgaaaaccaa gtcttgtagt ggagtggaat tttctacttc tggtcatgct tatactgata
      241 cagggaaagc atcaggcaac ctagagacca aatataaggt ctgtaactac gggctcatct
      301 tcacccaaaa gtggaataca gacaatactc ttgggacaga aatctcttgg gagaataagt
      361 tggctgaagg gttgaaactg acggttgata ccatatttgt accaaacaca gggaagaaga
      421 gtgggaaatt aaaggcctcc tatagacggg attgttttag tgtgggcagt aacgttgaca
      481 tagatttttc tggaccgacc atctatggct gggccgtgtt ggcctttgaa ggttggcttg
      541 ctggctacca gatgagtttt gacacagcca aatccaaact gtgtcagaat aattttgctc
      601 ttggttacaa ggctgaagac ttccaactgc atactcatgt aaacgatggc actgaatttg
      661 gaggctccat ctaccagaga gttaatgaga agatcgaaac atcaataaac ctggcatgga
      721 cagctggcag caacaacact cgttttggca tcgctgctaa gtataggctg gattgtagaa
      781 cttctctgtc tgccaaagta aacaatgcca gtttaattgg actgggttat acgcagagtc
      841 tccgaccggg agtcaaactg accctgtcag ctttagtgga tggaaagaac ttcaatgcag
      901 gaggccacaa ggttggcttg ggatttgaac tggaagctta atggggtttt gagtagagta
      961 tcaattgtcc ctggaaatga agagaaatga acccactatg ttttggcctt aaaattctgt
     1021 gaaatttcaa aagtgaactt tttattcttc caaagaattg taattcttcc cacaccgaag
     1081 tctagagatt acagatccat ccagtgggag ttccttgaag gcaatgcctg gaaattgtca
     1141 tgtttgtgcc acatttcagt tgagttctgc agagttaatt taaatatgtt cctcagcaac
     1201 aacgtagtgt cacgttaaag gaagtgatct gcccggtctg tacatcgagt cctgcatgtc
     1261 ccaactccac tttccatgac cttttgttac atcagtctct gctctagtga gacctttggt
     1321 ttgcatcaga gtaaaataaa cccatcacat ttggaacata a
//
