LOCUS       NM_001033683            2612 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus vesicle amine transport 1 (Vat1), mRNA.
ACCESSION   NM_001033683 XM_213484
VERSION     NM_001033683.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2612)
  AUTHORS   Liu,J., Dong,W., Wong,T.Y., Qiu,C., Wu,J., Zhao,J., Xia,J., Xie,S.
            and Song,X.
  TITLE     Proteome-wide analysis of protein alterations in response to
            aristolochic acids in rat kidney and liver tissues
  JOURNAL   Mol Omics 17 (3), 405-412 (2021)
   PUBMED   34008672
  REMARK    GeneRIF: Proteome-wide analysis of protein alterations in response
            to aristolochic acids in rat kidney and liver tissues.
REFERENCE   2  (bases 1 to 2612)
  AUTHORS   Mori,F., Tanigawa,K., Endo,K., Minamiguchi,K., Abe,M., Yamada,S.
            and Miyoshi,K.
  TITLE     VAT-1 is a novel pathogenic factor of progressive benign prostatic
            hyperplasia
  JOURNAL   Prostate 71 (14), 1579-1586 (2011)
   PUBMED   21394740
  REMARK    GeneRIF: We demonstrate that VAT-1 is a novel pathogenic factor in
            benign prostatic hyperplasia associated with cell proliferation.
REFERENCE   3  (bases 1 to 2612)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   4  (bases 1 to 2612)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   5  (bases 1 to 2612)
  AUTHORS   Eura,Y., Ishihara,N., Oka,T. and Mihara,K.
  TITLE     Identification of a novel protein that regulates mitochondrial
            fusion by modulating mitofusin (Mfn) protein function
  JOURNAL   J Cell Sci 119 (Pt 23), 4913-4925 (2006)
   PUBMED   17105775
  REMARK    GeneRIF: Cloning of Mitofusin-binding protein.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001033683.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC101882.1, SRR26360172.1677157.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676807 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-440               JAXUCZ010000010.1  86896972-86897411   c
            441-648             JAXUCZ010000010.1  86894204-86894411   c
            649-819             JAXUCZ010000010.1  86893667-86893837   c
            820-909             JAXUCZ010000010.1  86893474-86893563   c
            910-1151            JAXUCZ010000010.1  86891402-86891643   c
            1152-2612           JAXUCZ010000010.1  86889793-86891253   c
FEATURES             Location/Qualifiers
     source          1..2612
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..2612
                     /gene="Vat1"
                     /note="vesicle amine transport 1"
                     /db_xref="GeneID:287721"
                     /db_xref="RGD:1308943"
     exon            1..440
                     /gene="Vat1"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..1235
                     /gene="Vat1"
                     /note="mitofusin-binding protein; vesicle amine transport
                     protein 1 homolog (T californica)"
                     /codon_start=1
                     /product="synaptic vesicle membrane protein VAT-1 homolog"
                     /protein_id="NP_001028855.1"
                     /db_xref="GeneID:287721"
                     /db_xref="RGD:1308943"
                     /translation="MSAEREATEAATVAAAAEARAETGAGEGAPSQPPTVEVASDPQP
                     PPAPEASASASAPPLRCLVLTGFGGYDKVKLQSRPAVPPAPGPGQVTLRVRACGLNFA
                     DLMGRQGLYDRLPPLPVTPGMEGAGVVVAVGEGVSDRKAGDRVMVLNRSGMWQEEVTV
                     PSAQTFLMPEAMTFEEAAALLVNYITAYMVLFDFGNLRPGHSVLVHMAAGGVGMAALQ
                     LCRTVENVTVFGTASASKHEVLKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLG
                     GSDTAKGYHLLKPMGKVVTYGMANLLTGPKRNLMAMARTWWNQFSVTALQLLQANRAV
                     CGFHLGYLDGEVELVSRVVTHLLALYNQGHIKPRIDSVWPFEKVADAMRQMQEKKNIG
                     KVLLVPGPEKET"
     exon            441..648
                     /gene="Vat1"
                     /inference="alignment:Splign:2.1.0"
     exon            649..819
                     /gene="Vat1"
                     /inference="alignment:Splign:2.1.0"
     exon            820..909
                     /gene="Vat1"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1151
                     /gene="Vat1"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..2612
                     /gene="Vat1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcacgtcgg gagtctagcc atgtcggcgg agagggaggc aaccgaggcg gctactgtgg
       61 cggcggcagc cgaggcccgg gcggagaccg gagcagggga gggtgcgcct tcgcaacccc
      121 cgaccgtcga ggtggcgagc gacccgcagc cgccaccggc ccccgaagcg tcggcatccg
      181 cctcggctcc gccacttcgc tgcctggtac tcaccggctt cggtggctac gataaagtga
      241 agctgcagag ccgaccggcg gtgcccccgg ccccgggtcc cggtcaggtg acgctgcggg
      301 tgcgagcctg cgggctcaac tttgccgacc tcatgggccg ccaggggctg tacgaccggc
      361 tgccgcctct gccggtcacc cccggcatgg agggcgcggg cgtggtggtg gccgtgggcg
      421 agggtgtcag cgaccgtaag gcaggggata gggtgatggt gttgaaccgg tcagggatgt
      481 ggcaggagga agtgactgtg ccatcagccc agactttcct gatgccggag gccatgactt
      541 ttgaggaagc tgctgccttg ctggtcaatt atatcaccgc ctacatggtt ctctttgact
      601 tcggcaacct aagacccggc cacagcgtct tggtacacat ggctgcaggt ggtgttggca
      661 tggcagccct gcagttatgc cgcaccgtgg agaacgtgac agtgttcgga acggcctcag
      721 ccagcaagca tgaggtgctg aaggagaacg gggtcacaca ccccatcgac taccacacga
      781 ctgactatgt ggatgagatc aaaaagatct cccccaaagg agtagacatc gtcatggacc
      841 ctctgggtgg gtcggacact gcgaagggct accaccttct caaacccatg ggcaaagttg
      901 tcacttacgg aatggccaac ctgctgacgg gccccaagcg gaacctgatg gccatggccc
      961 gcacctggtg gaatcagttc agtgtgacag ctctgcagct gctgcaggcc aaccgagctg
     1021 tgtgcggctt ccacctgggc tacctggacg gtgaggtgga gctcgtcagt agagtggtta
     1081 cccacctcct ggctctgtac aatcagggcc acatcaaacc ccgaatcgac tcagtctggc
     1141 ccttcgagaa ggtggctgat gccatgaggc agatgcagga gaagaaaaac ataggcaaag
     1201 tcctcttggt tcctgggcct gagaaggaga cctagggcca gcggctgagg gccctggaga
     1261 gccaggaagg gggaagatgg gaagtcctgt tgtgttgccc accagcctct cacatttcat
     1321 cctgtcatga tgctctaccc tccctcccca gaaaaggtct ctgtgctgat gactgcttcc
     1381 ctgctctgag cttgctcttt gctcaggggc ctccctcccc cttccttccc tcgagagagg
     1441 ttgggaagtg accacttgga tgtctgagcc ctgctaaggg gacagggagg gtcagcagga
     1501 ggctggctgc ttcctgccac cccccctctc ccgggcctgc catgctgctt ttgtgccaag
     1561 gttagccagt ctgtccctgc cctatcctgt gtgcttcccc cttagcctca tcttccctcc
     1621 tgccccaccc ccacccaaag aatctgtgtc agctcaggat gtggggctaa tctgtgtgag
     1681 tgagtccagc atgtacccgt gcctcggtag tattcatgca acccaggccg acgaggccca
     1741 ccccaacctt gtctcccgtc cccagtgtcg taagcacaat tagacttctt ccacctccag
     1801 tttgctgcct cctaccgcaa gggcaggaat cagaccgact ccctggctca ccgctctggg
     1861 aggggtactg ggtaccccac ccttcactga ggtctctgga tttgtctcag tgccttagca
     1921 tcagaaaacc tgtgcttgtg tgtgtgtgtg tagcgggcag ccctatctct ggctcctttt
     1981 ccacccttct ccccagtgcc ttcctcgtcc tggtggagct gaggcctact cctccccagt
     2041 ccaacactgc caaaaatctg tgtatgtgcc aggggtcggg ggtagggagt agctctaacc
     2101 tctggggatc aattgttttt actgtggtct ggggcctggc ctatctgtca gtggtggaga
     2161 atgaagaggc agtatactgg atcagcccga gttctgggag acactgctgg gtctcattct
     2221 gggaccgaag tgaaactcca agcacattcc ctttgctatc taggaggctc ctgccttccc
     2281 agagctctgt tgttcagccc caaactctgt ttacactggt gggggagaag gagctcgggt
     2341 aggggaatta ctgggctggt taaaaggaca ggggcttctg gagccaaagt ggggaccttt
     2401 gaggctaggt gggggtcacc tgctgcttct gagcttggat tagagagagc tgttactcca
     2461 gccactgtca gaaggagtgt gaggggaggg acccagcctc tctcttgtct aattgaggcc
     2521 tccatgtagg aagtgtgatt tttgcttttg tgtcccccac cccattacca cagctgcctt
     2581 tgtgtctgtg tcaataaaca gccaaaccct ga
//
