LOCUS       NM_001109382            2739 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus vasorin (Vasn), mRNA.
ACCESSION   NM_001109382 XM_001055204
VERSION     NM_001109382.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2739)
  AUTHORS   Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S and Zaidel-Bar R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2739)
  AUTHORS   Choksi S, Lin Y, Pobezinskaya Y, Chen L, Park C, Morgan M, Li T,
            Jitkaew S, Cao X, Kim YS, Kim HS, Levitt P, Shih G, Birre M, Deng
            CX and Liu ZG.
  TITLE     A HIF-1 target, ATIA, protects cells from apoptosis by modulating
            the mitochondrial thioredoxin, TRX2
  JOURNAL   Mol Cell 42 (5), 597-609 (2011)
   PUBMED   21658601
REFERENCE   3  (bases 1 to 2739)
  AUTHORS   Malapeira J, Esselens C, Bech-Serra JJ, Canals F and Arribas J.
  TITLE     ADAM17 (TACE) regulates TGFbeta signaling through the cleavage of
            vasorin
  JOURNAL   Oncogene 30 (16), 1912-1922 (2011)
   PUBMED   21170088
REFERENCE   4  (bases 1 to 2739)
  AUTHORS   Zhang Y, Li Y, Qiu F and Qiu Z.
  TITLE     Comprehensive analysis of low-abundance proteins in human urinary
            exosomes using peptide ligand library technology, peptide OFFGEL
            fractionation and nanoHPLC-chip-MS/MS
  JOURNAL   Electrophoresis 31 (23-24), 3797-3807 (2010)
   PUBMED   21082674
REFERENCE   5  (bases 1 to 2739)
  AUTHORS   Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta
            R, Wang NS and Knepper MA.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 2739)
  AUTHORS   Schroder B, Wrocklage C, Pan C, Jager R, Kosters B, Schafer H,
            Elsasser HP, Mann M and Hasilik A.
  TITLE     Integral and associated lysosomal membrane proteins
  JOURNAL   Traffic 8 (12), 1676-1686 (2007)
   PUBMED   17897319
REFERENCE   7  (bases 1 to 2739)
  AUTHORS   Ikeda Y, Imai Y, Kumagai H, Nosaka T, Morikawa Y, Hisaoka T, Manabe
            I, Maemura K, Nakaoka T, Imamura T, Miyazono K, Komuro I, Nagai R
            and Kitamura T.
  TITLE     Vasorin, a transforming growth factor beta-binding protein
            expressed in vascular smooth muscle cells, modulates the arterial
            response to injury in vivo
  JOURNAL   Proc Natl Acad Sci U S A 101 (29), 10732-10737 (2004)
   PUBMED   15247411
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474017.1.
            
            On Oct 4, 2007 this sequence version replaced XM_001055204.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB614933.1, FQ151950.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132299, SAMEA5756307
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2739
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..2739
                     /gene="Vasn"
                     /note="vasorin"
                     /db_xref="GeneID:679921"
                     /db_xref="RGD:1598149"
     exon            1..146
                     /gene="Vasn"
                     /inference="alignment:Splign:2.1.0"
     exon            147..2739
                     /gene="Vasn"
                     /inference="alignment:Splign:2.1.0"
     CDS             156..2177
                     /gene="Vasn"
                     /codon_start=1
                     /product="vasorin precursor"
                     /protein_id="NP_001102852.1"
                     /db_xref="GeneID:679921"
                     /db_xref="RGD:1598149"
                     /translation="MHSRSCLPPLLLLLLVLLGSGVQSCPSGCQCNQPQTVFCTARQG
                     TTVPRDVPPDTVGLYIFENGITTLDVGCFAGFPGLQLLDLSQNQITSLPGGIFQPLVN
                     LSNLDLTANKLHEISNETFRGLRRLERLYLGKNRIRHIQPGAFDALDHLLELKLPDNE
                     LRVLPPLHLPRLLLLDLSHNSIPALEAGILDTANVEALRLAGLGLRQLDEGLFGRLRN
                     LHDLDVSDNQLGHMPSVIQGLRGLTRLRLAGNTRIAQIRPEDLAGLTALQELDVSNLS
                     LQALPSDLSSLFPRLRLLAAARNPFNCLCPLSWFGPWVRESHVVLASPEETRCHFPPK
                     NAGRLLLELDYADFGCPVTTTTATVPTIRPTVREPTPSTSSQAPTWPSPTEPTTQAPI
                     VLSTAPPTMRPAPQPQDCPASICLNGGSCRVGAKHHLECLCPEGFIGLYCESPVEQRT
                     KPSSIPDTPRPPRLLPLRIEPVSPTSLRVELQRYLQGNTVQLRSLRLTYRNLSGPDKR
                     LVTLRLPASLAEYTVTQLRPNATYSICVTALGAGRTPEGEEACGEANTPQAVRSNHAP
                     VTQAREGNLPLLIAPALAAVLLAVLAASGAVYCVRRARASSTAQDKGQVGPGTGPLEL
                     EGVKVPLEPGSKASEGGGEALSGGPECEVPLMGYPGPSLQGVLPAQPYI"
ORIGIN      
        1 ggagcccggg gttgggagac ccggacgcag tagcctccgg atcccgggac cccggacctt
       61 tcaggaccgg ccggaggcga aggactgagg ccccattgag gccttgggcc gcaccgcccc
      121 gctccctcag ccacagtcgt ctcccgggac agaagatgca ctccaggagc tgcctgccac
      181 ctcttctgtt gttgctcctg gtgctcctgg ggtctggagt acagagctgc ccatcaggct
      241 gccagtgcaa ccaaccacag acagtcttct gcactgcccg tcagggaacc acggtgcccc
      301 gagacgtgcc gcctgacaca gtgggcctgt acatctttga gaacggcatc actacacttg
      361 atgtaggctg ttttgctggc ttcccaggcc tgcagcttct ggacttgtca cagaaccaga
      421 tcactagcct gcccggtggc atctttcagc cacttgtgaa cctcagtaac ctggacctga
      481 ctgctaacaa actgcacgag atctccaacg agaccttccg tggcctgcgg cgcctcgaac
      541 gcctctacct gggcaagaac cgcattcgcc acatccagcc tggtgccttc gatgcacttg
      601 accacctcct ggagctcaag ctgccagaca atgagcttcg ggtgctgccc ccactgcact
      661 tgcctcgcct gctgctgctt gacctcagcc acaacagtat cccagccctg gaagctggaa
      721 tactggatac tgccaatgtg gaggcactgc ggctggctgg cctcgggctg cggcagctgg
      781 atgaggggct ttttggccgc cttcgcaacc tccatgacct ggatgtttct gacaaccagt
      841 tggggcacat gccctccgtg attcaaggcc tgcgtggcct gacacgcctg cggctggctg
      901 gcaacacccg gattgcccag atccggcccg aggacctcgc tggcctgact gccctacagg
      961 aactggatgt gagcaacctg agcctgcagg ccctgcccag tgacctctcc agtctctttc
     1021 cccgcctgcg cctcctagca gctgcccgaa acccctttaa ctgcttatgc cccttgagct
     1081 ggtttggtcc ttgggttcgt gagagccatg ttgtgctggc cagccctgag gagacacgtt
     1141 gtcacttccc acccaagaac gccggccgac tgctcctgga gctggattat gcagattttg
     1201 gctgcccagt caccactacc acagccacag ttcctactat aaggcctact gtcagggagc
     1261 ccacaccttc aacttccagc caagctccca cctggcccag ccccacagag ccaactaccc
     1321 aggcccccat cgtactgtcc actgccccac caaccatgag gccggctcct cagccccagg
     1381 actgtccagc atccatctgc ctgaatggtg gtagctgccg tgtaggggca aaacaccacc
     1441 tggagtgcct gtgccccgag ggcttcattg gcctgtactg tgagagtccc gtggaacaaa
     1501 ggacaaagcc cagctccata ccggacaccc cacggccccc gcggctgctg cctctgcgca
     1561 ttgagccggt gagccccacc tccctgcgtg tggagctgca gcgctacctg cagggcaaca
     1621 ccgtgcagct gcggagcctc cggctcacct accgcaacct gtctggccct gacaagcggc
     1681 tggtgacgct gcggctgcct gcttcacttg cagagtacac agtcacccag ctgcggccca
     1741 atgccaccta ttctatctgt gtcacagccc tgggagctgg gcggacacct gaaggtgagg
     1801 aggcctgtgg ggaggccaac actccccagg ccgtccgctc caaccatgcc ccagtcaccc
     1861 aggcccggga gggcaacctg ccactcctca ttgcacccgc cctggctgct gtgcttctgg
     1921 ctgtgttggc tgcctcgggg gcagtctact gtgtgcgacg ggcgcgggca agttccacag
     1981 ctcaggacaa agggcaggtg ggaccaggga ccgggcccct ggaactagag ggggtgaaag
     2041 tccccttgga gccaggctcc aaggcatcag agggaggcgg ggaggcccta tcaggtggtc
     2101 ctgaatgtga ggtgcccctc atgggctacc cagggcccag tcttcagggg gtcctccctg
     2161 ctcagcccta catttaagca cgtgagaagg agcagccagg aggctgggct ttcagtctcc
     2221 accctcctgc tgctacagaa ggaagttctc aatgcgcacc acagtgcaca tgtgtgaccg
     2281 gtgctgtggg acagcagcca gtccccgacc ctctctgggc tgggtcatct gaaagctgct
     2341 acagcccaaa tgaactccca gcaccagcat ccagtacaga gcctgctgcc ttgcgcagtc
     2401 tgcagtcctg ggacgggaac cctgccatgt gctggtagca tggctaggat gttgggcttc
     2461 ccgggccctg gggtctggta accagtgaag gaagccccca aaaatagtgg gtagggaagg
     2521 cactagggcc gtggccgtgg ccccgaaagt gcaggaacac ttgaaactgg aaaggaaggt
     2581 gctctgggca cacgtggatt tgcttctatt gttttgtttt tctcctaatg tatttataaa
     2641 agatcttttc ccgtttatgc tgggaaaaag tgtttttcaa actcagtgac aaggactttt
     2701 ggtttttgta agactattga tgatatgaag gccttttgt
//
