LOCUS       NM_053292               3980 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus valyl-tRNA synthetase 1 (Vars1), mRNA.
ACCESSION   NM_053292 XM_001076616
VERSION     NM_053292.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3980)
  AUTHORS   Hurt,P., Walter,L., Sudbrak,R., Klages,S., Muller,I., Shiina,T.,
            Inoko,H., Lehrach,H., Gunther,E., Reinhardt,R. and Himmelbauer,H.
  TITLE     The genomic sequence and comparative analysis of the rat major
            histocompatibility complex
  JOURNAL   Genome Res 14 (4), 631-639 (2004)
   PUBMED   15060004
REFERENCE   2  (bases 1 to 3980)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   3  (bases 1 to 3980)
  AUTHORS   Vilalta,A., Donovan,D., Wood,L., Vogeli,G. and Yang,D.C.
  TITLE     Cloning, sequencing and expression of a cDNA encoding mammalian
            valyl-tRNA synthetase
  JOURNAL   Gene 123 (2), 181-186 (1993)
   PUBMED   8428657
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX883045.1.
            
            On Oct 13, 2007 this sequence version replaced XM_001076616.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760389
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..3980
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..3980
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /note="valyl-tRNA synthetase 1"
                     /db_xref="GeneID:25009"
                     /db_xref="RGD:3950"
     exon            1..88
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            89..507
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     CDS             121..3915
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /EC_number="6.1.1.9"
                     /note="valyl-tRNA synthetase 2; valRS"
                     /codon_start=1
                     /product="valine--tRNA ligase"
                     /protein_id="NP_445744.1"
                     /db_xref="GeneID:25009"
                     /db_xref="RGD:3950"
                     /translation="MSILYVSPHPDAFPSLRALIAARYGEAGDGPGWGGPHPRICLQP
                     PPSSRTPFPPPRLPALEQGPGGLWVWGAPAVAQLLWPAGLGGPGGSRAAVLVQQWVSY
                     ADTELTPAACGATLPALGLRGPGQDPQAALGALGKALNPLEEWLRLHTYLAGDAPTLA
                     DLAAVTALLLPFRYVLDPSARRIWGNVTRWFNTCVRQPEFRAVLGEVVLYSGARSVTQ
                     QPGSEITAPQKTAAQLKKEAKKREKLEKFQQKQKTQQQQPAHGEKKPKPEKKEKRDPG
                     VITYDLPTPPGEKKDVSGTMPDSYSPQYVEAAWYPWWERQGFFKPEYGRPSVSAPNPR
                     GVFMMCIPPPNVTGSLHLGHALTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVV
                     EKKLWKERGLNRHQLGREAFLQEVWKWKAEKGDRIYHQLKKLGSSLDWDRACFTMDPK
                     LSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDKKELTGRTLLSVPGYKE
                     KVEFGVLVSFAYKVQGSDSDEEVVVATTRIETMLGDVAVAVHPKDPRYQHLKGKSVVH
                     PFLSRSLPIVFDDFVDMEFGTGAVKITPAHDQNDYEVGQRHRLEAISIMDSKGALVNV
                     PPPFLGLPRFEARKAVLAALKEQGLFRGIKDNPMVVPLCNRSKDVVEPLLRPQWYVRC
                     GEMAQAASAAVTRGDLRILPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPAYFITVHD
                     PAVPPGEDPDGRYWVSGRTEAEAREKAAREFGVSPDKISLQQDEDVLDTWFSSGLFPF
                     SIFGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTEKLPFREVYLHAIVR
                     DAHGRKMSKSLGNVIDPLDVIHGVSLQGLHDQLLNSNLDPSEVEKAKEGQRADFPAGI
                     PECGTDALRFGLCAYTSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLGKGFVPSP
                     TSKPEGHESLVDRWIRSRLAEAVRLSNEGFQAYDFPAVTTAQYSFWLYELCDVYLECL
                     KPVLNGVDQVAADCARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRTPNAPASLCV
                     TPYPEPSECSWKDPEAEAALELALSITRAVRSLRADYNLTRTRPDCFLEVADEATGAL
                     ASAVSAYVQTLASAGVVAVLALGAPAPQGCAVAVASDRCSIHLQLQGLVDPARELGKL
                     QAKRSEAQRQAQRLQERRAASGYSAKVPLEVQEADEVKLQQTEAELRKVDEAIALFQK
                     ML"
     exon            508..642
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            643..781
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            782..906
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            907..991
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1092
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1220
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1385
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1467
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1468..1587
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1588..1696
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..1791
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1792..1882
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            1883..2007
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2008..2111
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2112..2270
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2271..2361
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2362..2467
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2468..2538
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2539..2664
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2665..2769
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2770..2838
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2839..2917
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            2918..3045
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            3046..3201
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            3202..3408
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            3409..3520
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            3521..3846
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
     exon            3847..3980
                     /gene="Vars1"
                     /gene_synonym="Bat6; G7a; TrsVal; Vars; Vars2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggagagctg cctccgccgc ccgccacctc ctccccggcc gccctgtggg gccgcggccg
       61 tggccggctg aggagatctc ccggccaagt cactccaccg cgctccgacc ctgcacagcc
      121 atgtccatcc tctacgtctc tccccacccc gacgccttcc ccagcctgcg agccctcatc
      181 gctgcccgct acggggaagc tggggacggt cccgggtggg gaggccctca ccctcgcatc
      241 tgcctgcagc ctcccccgag cagccggact ccattccccc cgcctcgcct gcccgccctg
      301 gagcaggggc ctggcggcct gtgggtgtgg ggggccccgg ctgtagctca gctgctgtgg
      361 ccagcaggcc tgggaggacc cgggggcagc cgggcagctg tcctggtcca gcagtgggtc
      421 agttatgccg acacggagct cacaccagct gcctgcgggg cgacgctgcc tgctctagga
      481 cttcgaggtc ctggtcagga tccccaggct gcccttgggg ccctgggcaa ggccttgaac
      541 cccttggagg aatggcttcg tctgcacacc tacctggctg gggacgctcc cactctggct
      601 gacttagctg ctgtgacagc cttactgctg cccttccgat acgttctgga cccttctgcc
      661 cgccggatct ggggtaatgt gactcgctgg tttaacacct gtgtccggca accagaattc
      721 cgggctgtgc tgggagaagt ggtcctgtac tcaggggcca ggtctgtcac tcagcagcca
      781 ggttccgaga tcactgcacc ccaaaagaca gctgctcagc tcaagaaaga agcaaagaaa
      841 cgggagaaac tagagaaatt ccaacagaag cagaagacgc agcagcagca gccggcacac
      901 ggggagaaga aaccaaaacc agagaagaag gagaagcgag accccggggt cattacctat
      961 gacctcccta ccccacctgg ggagaagaaa gacgtaagtg gcaccatgcc cgactcctac
     1021 agccctcagt atgtggaggc tgcctggtac ccttggtggg agcggcaggg cttcttcaag
     1081 ccagagtacg ggcgtcctag cgtgtcagca ccaaatcccc gaggtgtctt catgatgtgc
     1141 atcccacccc ccaacgtgac aggttccctg cacctgggcc acgcgctcac caacgccatc
     1201 caggactccc tgactcgatg gcaccgcatg cggggggaga ccaccctatg gaacccaggc
     1261 tgtgaccatg ctggcatcgc cacccaggtg gtggtggaaa agaaactctg gaaagagcgg
     1321 ggtctgaacc gtcaccagct gggccgcgag gcctttcttc aggaggtctg gaagtggaaa
     1381 gcggagaagg gtgacaggat ttaccaccaa ttaaagaaac ttggcagctc cttggactgg
     1441 gatcgagcct gcttcaccat ggatccaaaa ttgtcagcaa ctgtgacaga agcttttgtt
     1501 aggctccatg aagaaggggt catttaccgc agtacccgcc tggtcaactg gtcctgcacc
     1561 ctcaactctg ccatttctga catcgaggtg gataagaaag agctgacggg ccgcaccctg
     1621 ctctctgtgc ctggctacaa ggagaaggtg gagtttgggg tcctcgtgtc ctttgcctac
     1681 aaggtccaag gctcagacag cgacgaggag gtggtggtgg caacaacccg gatcgagaca
     1741 atgctggggg acgtggctgt ggctgtgcac cccaaagatc ccagatacca gcatttaaag
     1801 ggaaagagtg tcgtccaccc gttcttgtcc cggagccttc ccattgtctt tgatgacttt
     1861 gtggacatgg agtttggcac aggtgctgtg aagatcaccc cggcccatga ccagaatgac
     1921 tatgaggttg ggcagcgaca taggctggag gccattagca tcatggactc gaagggggcc
     1981 cttgtcaatg tgcctccacc tttcctgggc ctgcccaggt ttgaggccag gaaggctgtg
     2041 ctggcggccc tgaaggagca gggcctgttc cgcggcatca aggacaaccc catggtagtg
     2101 ccactatgca accgctccaa ggatgtggtg gagcctctgc taaggccaca gtggtacgtg
     2161 cgctgtgggg agatggctca ggccgccagt gctgccgtga cccggggaga cctccgtata
     2221 ctgcctgagg cccatcagcg gacgtggcat tcttggatgg acaacatccg agactggtgc
     2281 atctctcggc agctgtggtg gggccaccga atccctgcct acttcatcac tgtccatgac
     2341 ccagcggtac cccctgggga ggaccctgat gggcggtact gggtaagcgg acgcactgaa
     2401 gcagaggccc gggagaaggc agcacgggaa tttggagtgt cccctgacaa gatcagcctt
     2461 cagcaagatg aggatgtgtt agacacctgg ttctcgtctg gtctctttcc cttctccatc
     2521 tttggctggc ccaatcagtc agaagatctc agtgtgttct accctgggac cctgctggag
     2581 acgggccatg atatcctctt cttctgggtg gcgcgaatgg tcatgcttgg cctgaagctc
     2641 actgagaagc tgcccttcag agaggtctac ctccatgcaa tcgtgcggga cgctcatggc
     2701 cggaagatga gcaagtctct cggcaatgtc atcgaccccc tggatgtcat ccatggagtt
     2761 tccttgcagg gcctccatga ccaactactg aacagcaacc tggatcccag tgaggtggag
     2821 aaagccaaag aaggacagag ggccgacttt ccagcaggga ttcccgagtg tggcactgat
     2881 gccctacgct ttggactctg tgcctacaca tcccaaggtc gagacattaa cctggatgtg
     2941 aacaggatcc tggggtaccg tcacttctgc aacaaactct ggaatgccac caagtttgct
     3001 ttgcgcggcc ttgggaaggg ctttgtaccc tcaccaacct ccaagccgga agggcacgag
     3061 agcctggtgg accgctggat ccgcagccgg ctggcggagg ccgtgaggct cagcaatgaa
     3121 ggcttccagg cttatgattt cccagccgtc accactgccc agtacagctt ttggctctat
     3181 gagctctgtg atgtctactt ggagtgccta aaacccgttc tgaacggagt ggaccaggta
     3241 gcagcagact gtgctcggca aaccctctac acctgcctgg atgtcggcct gcggctgctc
     3301 tcacccttca tgccctttgt cacagaggag ctattccaga ggctgcctcg gcggacacca
     3361 aacgctcctg ctagcctctg tgtcaccccc tacccagagc cctcagagtg ctcctggaag
     3421 gaccctgaag ccgaagctgc tcttgagcta gcgctgagca tcactagagc tgtgcgctcc
     3481 ctgcgtgcag actacaacct gacccggacc aggcccgact gtttcttgga agtagctgat
     3541 gaggctacgg gtgccttggc ctcggcagtg tcggcctacg tgcagactct ggccagtgcg
     3601 ggtgtggtgg ccgtcctggc cctgggtgct cccgcaccac agggctgcgc tgtggctgtg
     3661 gcctcagacc gctgctccat ccacctgcag ctgcaggggc tcgtggaccc agcccgggag
     3721 ctgggcaagc tgcaggccaa gcggagtgag gcacagcgac aggctcagcg gctgcaggag
     3781 cgccgtgctg cctctggcta ctcagcaaag gtgccccttg aggtccagga ggccgacgaa
     3841 gtgaagttac aacagacaga ggcggagctc aggaaggtgg atgaggccat cgccctgttt
     3901 cagaagatgc tgtgacaccc ccagttccaa cccccagtgt tccaccaaac agggatggca
     3961 gcaataaaat attttgccaa
//
