LOCUS       NM_001109584            2597 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus VANGL planar cell polarity protein 1 (Vangl1),
            mRNA.
ACCESSION   NM_001109584 XM_001072325 XM_001072362 XM_001072392
VERSION     NM_001109584.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2597)
  AUTHORS   DiTommaso T, Jones LK, Cottle DL, Gerdin AK, Vancollie VE, Watt FM,
            Ramirez-Solis R, Bradley A, Steel KP, Sundberg JP, White JK and
            Smyth IM.
  CONSRTM   WTSI Mouse Genetics Program
  TITLE     Identification of genes important for cutaneous function revealed
            by a large scale reverse genetic screen in the mouse
  JOURNAL   PLoS Genet 10 (10), e1004705 (2014)
   PUBMED   25340873
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2597)
  AUTHORS   Dai D, Li L, Huebner A, Zeng H, Guevara E, Claypool DJ, Liu A and
            Chen J.
  TITLE     Planar cell polarity effector gene Intu regulates cell
            fate-specific differentiation of keratinocytes through the primary
            cilia
  JOURNAL   Cell Death Differ 20 (1), 130-138 (2013)
   PUBMED   22935613
REFERENCE   3  (bases 1 to 2597)
  AUTHORS   Katoh Y and Katoh M.
  TITLE     Comparative genomics on Vangl1 and Vangl2 genes
  JOURNAL   Int J Oncol 26 (5), 1435-1440 (2005)
   PUBMED   15809738
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474015.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001072362.1, XM_001072392.1, XM_001072325.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2597
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..2597
                     /gene="Vangl1"
                     /note="VANGL planar cell polarity protein 1"
                     /db_xref="GeneID:690366"
                     /db_xref="RGD:1597324"
     exon            1..98
                     /gene="Vangl1"
                     /inference="alignment:Splign:2.1.0"
     exon            99..282
                     /gene="Vangl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             212..1792
                     /gene="Vangl1"
                     /note="vang, van gogh-like 1; vang-like 1 (van gogh,
                     Drosophila)"
                     /codon_start=1
                     /product="vang-like protein 1"
                     /protein_id="NP_001103054.1"
                     /db_xref="GeneID:690366"
                     /db_xref="RGD:1597324"
                     /translation="MDTESTYSGYSYYSSHSKKSHRQGERTRERHKSPRNKDGRGSEK
                     SVTIQAPTGEPLLANDSAHTGTEEVQDDNWGETTTAITGTSEHSISQEDIARISKDME
                     DSVGLDCKRYLGLTIASFLGLLVFLTPIAFILLPQILWREELKPCGAICEGLLISVSF
                     KLLILLIGTWALFFRKQRADVPRVFVFRALLLVLIFLFVVSYWLFYGVRILDSRDQNY
                     KDIVQYAVSLVDALLFIHYLAIVLLELRQLQPMFTLQVVRSTDGESRFYSLGHLSIQR
                     AALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDGPSNNATGQSRAMIAAA
                     ARRRDSSHNELYYEEAEHERRVKKRRARLVVAVEEAFIHIQRLQAEEQQKSPGEVMDP
                     REAAQAIFPSMARALQKYLRTTRQQHYHSMESILQHLAFCITNSMTPKAFLERYLSAG
                     PTLQYDKDRWLSTQWRLISDEAVTNGLRDGIVFVLKCLDFSLVVNVKKIPFIVLSEEF
                     IDPKSHKFVLRLQSETSV"
     exon            283..421
                     /gene="Vangl1"
                     /inference="alignment:Splign:2.1.0"
     exon            422..1029
                     /gene="Vangl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1163
                     /gene="Vangl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1164..1296
                     /gene="Vangl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..1531
                     /gene="Vangl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1532..2597
                     /gene="Vangl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccgcggc ggggctgtgc ctccactgca gcccagcgca ggccgcggag ccggggcgct
       61 tcagccgaga gcgtggagcg cggcgggctg gcgccgggag tcctgttgaa gagtagcggc
      121 tctgagtccc acaaggcctt cagagctagt gggtgagact gctcctggga gaacagcccc
      181 gctccttcat cagaggaagc ttgccgttgc tatggatacc gaatccactt attctggata
      241 ttcctactac tcaagccatt caaaaaaatc tcacaggcaa ggggaaagaa caagagaaag
      301 acacaaatca ccacggaata aagatggcag ggggtcagaa aagtctgtca ccatccaggc
      361 tcccactgga gagcccttgc tggcgaatga ctctgcccac acaggcacag aggaagttca
      421 ggatgacaac tggggagaga ccaccacagc catcacaggc acctcagagc acagtatatc
      481 ccaagaggac attgccagga ttagcaagga catggaggac agtgtggggc tggattgcaa
      541 gcgctacctg ggcctcacca ttgcctcgtt cctcggacta ctcgtcttcc tcacccccat
      601 cgccttcatc ctgctacccc agatcctgtg gagggaggag ctgaaaccct gtggcgccat
      661 ttgtgaggga cttctcatat ctgtatcgtt caaactgctt atcctgctca tcggaacctg
      721 ggcgcttttc ttccgcaagc aaagagcgga tgtgccgcgg gtgtttgtgt tccgagcgct
      781 gttattggtc cttatctttc tttttgtggt ttcttattgg cttttttatg gggtccgcat
      841 tctggactcc cgggaccaaa attacaagga catcgtgcaa tatgcagtct ctctcgtgga
      901 tgcgctgctt ttcatccact accttgccat cgtcctgctg gaactgaggc agctgcaacc
      961 catgttcaca ctgcaggtgg tccgctccac cgacggagag tcccgcttct acagcttggg
     1021 acacttgagc atccagcgag cagccttggt ggttctggaa aattactaca aggacttcac
     1081 tatctataac ccgaacctcc taacagcatc caaattccga gcagccaagc acatggctgg
     1141 cctgaaagtc tacaatgtag atgggcccag taacaatgcc actggtcagt cccgagccat
     1201 gatcgctgca gcagctcggc gcagggactc cagccacaac gagttgtatt atgaagaggc
     1261 cgaacacgag cggagggtga agaagcggag agcgagactg gtggtggctg tggaagaagc
     1321 cttcatccac atccagcgcc tccaggctga ggagcagcag aagtctccag gggaggtgat
     1381 ggaccccaga gaggcggctc aggccatctt cccctccatg gccagggcgc tgcagaaata
     1441 cctgcgcacc acccggcagc agcactacca cagcatggag agcatcctgc agcacctggc
     1501 cttctgcatc accaacagca tgacccccaa ggctttcctt gaacgatacc tcagtgcagg
     1561 ccccaccttg cagtatgaca aggatcgatg gctctcgaca cagtggagac ttattagtga
     1621 cgaggctgtg acgaacgggt tacgggatgg aattgttttc gtccttaaat gcttggactt
     1681 cagcctcgtg gtcaatgtga agaaaatccc attcatagtt ctctcagaag agttcataga
     1741 ccctaaatct cacaagtttg ttcttcgctt acagtccgag acatcagtct aaaatttcta
     1801 tgcttgtggc tttatggaaa acaaaagaag aatatataaa tatatatata tatgtgtgtg
     1861 tatgtccagg gggaagttct tttataaaga ttttttttaa ttcttcaatg ctgactcaaa
     1921 ctggcagagg atagaccagt atccttcaac catctgcact ttatttggaa gaaagcagat
     1981 gtctaccccg acaagcaact ggtggcatct gacttaacta gataggactt ctgaagaagc
     2041 tgttccccag agtttttgtg acagctgtaa accaaagtgt agctgctgtg tcctcgggag
     2101 ccatgcctta caactgtccc tgcctgcggc ccagtaccac acccatctgt acttctggtc
     2161 aaccccttca tagattctag gggacttact ttattctgct tcaggaaatc agacactaca
     2221 cactcatgtg tgtgtttgta tgcataatta tccacatcac cacagcaccc tggggagtgg
     2281 tgggcagtcc aggaaatgtc cacccacccg agtctttgtt ctttgctgcc ttacattggc
     2341 gaagagaaag aaaggacccg acagaaaatg ttcactgctg gtttacagct gttaagtgat
     2401 tggctttcca ttttccagag agagagccta cctgccctgt ttctggctct gctcctctgt
     2461 tggcctgagg cacgtagccg ttccttagcc ctaggactgc ctacccaggc ttcactctgt
     2521 acccactctc ctgagcatct ggaccatggc cgcacccagt gggcagctct ggccaggcta
     2581 gattggccct ccagaac
//
