LOCUS       NM_053555                670 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus vesicle-associated membrane protein 5 (Vamp5),
            mRNA.
ACCESSION   NM_053555
VERSION     NM_053555.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 670)
  AUTHORS   Takahashi,M., Tajika,Y., Khairani,A.F., Ueno,H., Murakami,T. and
            Yorifuji,H.
  TITLE     The localization of VAMP5 in skeletal and cardiac muscle
  JOURNAL   Histochem Cell Biol 139 (4), 573-582 (2013)
   PUBMED   23180306
REFERENCE   2  (bases 1 to 670)
  AUTHORS   Hasan,N., Corbin,D. and Hu,C.
  TITLE     Fusogenic pairings of vesicle-associated membrane proteins (VAMPs)
            and plasma membrane t-SNAREs--VAMP5 as the exception
  JOURNAL   PLoS One 5 (12), e14238 (2010)
   PUBMED   21151919
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 670)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (bases 1 to 670)
  AUTHORS   Schwenk,R.W., Dirkx,E., Coumans,W.A., Bonen,A., Klip,A., Glatz,J.F.
            and Luiken,J.J.
  TITLE     Requirement for distinct vesicle-associated membrane proteins in
            insulin- and AMP-activated protein kinase (AMPK)-induced
            translocation of GLUT4 and CD36 in cultured cardiomyocytes
  JOURNAL   Diabetologia 53 (10), 2209-2219 (2010)
   PUBMED   20582536
REFERENCE   5  (bases 1 to 670)
  AUTHORS   Rose,A.J., Jeppesen,J., Kiens,B. and Richter,E.A.
  TITLE     Effects of contraction on localization of GLUT4 and v-SNARE
            isoforms in rat skeletal muscle
  JOURNAL   Am J Physiol Regul Integr Comp Physiol 297 (5), R1228-R1237 (2009)
   PUBMED   19675279
  REMARK    GeneRIF: VAMP2, VAMP5, and VAMP7 may be involved in translocation
            of GLUT4 during muscle contractions.
REFERENCE   6  (bases 1 to 670)
  AUTHORS   Zeng,Q., Tran,T.T., Tan,H.X. and Hong,W.
  TITLE     The cytoplasmic domain of Vamp4 and Vamp5 is responsible for their
            correct subcellular targeting: the N-terminal extenSion of VAMP4
            contains a dominant autonomous targeting signal for the trans-Golgi
            network
  JOURNAL   J Biol Chem 278 (25), 23046-23054 (2003)
   PUBMED   12682051
REFERENCE   7  (bases 1 to 670)
  AUTHORS   Zeng,Q., Subramaniam,V.N., Wong,S.H., Tang,B.L., Parton,R.G.,
            Rea,S., James,D.E. and Hong,W.
  TITLE     A novel synaptobrevin/VAMP homologous protein (VAMP5) is increased
            during in vitro myogenesis and present in the plasma membrane
  JOURNAL   Mol Biol Cell 9 (9), 2423-2437 (1998)
   PUBMED   9725904
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FQ127573.1, FQ217123.1 and JAXUCZ010000004.1.
            
            On Dec 3, 2020 this sequence version replaced NM_053555.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ217123.1, FQ127573.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840121, SAMN16676788
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                FQ127573.1         1-11
            12-372              FQ217123.1         1-361
            373-184426853       JAXUCZ010000004.1  1-184426481
            184426854-184427150 FQ217123.1         363-659
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q32"
     gene            1..670
                     /gene="Vamp5"
                     /note="vesicle-associated membrane protein 5"
                     /db_xref="GeneID:89818"
                     /db_xref="RGD:620419"
     exon            1..116
                     /gene="Vamp5"
                     /inference="alignment:Splign:2.1.0"
     CDS             114..422
                     /gene="Vamp5"
                     /note="VAMP-5; myobrevin"
                     /codon_start=1
                     /product="vesicle-associated membrane protein 5"
                     /protein_id="NP_446007.1"
                     /db_xref="GeneID:89818"
                     /db_xref="RGD:620419"
                     /translation="MAGKELERCQRQADQVTEIMLNNFDKVLERDGKLSELQQRSDQL
                     LDMSSAFSKTTKTLAQQKRWENIRCRVYLGLAVAGGLLLILVVLLVIFLPSGEDSSKP
                     "
     exon            117..254
                     /gene="Vamp5"
                     /inference="alignment:Splign:2.1.0"
     exon            255..670
                     /gene="Vamp5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaccgccgg tccgccccgc cccgccgctt cctctgcggc cgcgggcact gaggcagcgc
       61 gaggcagagg agccggagcc cgcgatcagg cagcggcggc agctgcggag gcgatggcag
      121 ggaaagaatt ggagcgatgc cagcggcagg cagaccaagt gacggaaatc atgctcaaca
      181 atttcgacaa ggtcctggaa cgcgatggga agctgtcaga gttgcagcag cgctcagacc
      241 agctcctgga catgagttct gccttcagca agacaaccaa gactttagcc cagcagaagc
      301 gctgggagaa tatccggtgc cgggtctacc tggggctagc cgtggctggc ggccttctcc
      361 tcatcctggt tgtgcttctg gtcatctttc ttccgagtgg agaggacagt agtaaaccat
      421 aggcctagga tgcaggcacg gccttaggga ctggggcctg acccagcctg gcctgaagga
      481 aaggctgaat ggctgcactg gcctgttctg gtctccagag aatcctggtg tttgcttcca
      541 tctaggacac cccactgact gctgaagggc atgctggata tgtgcacctc tgcgtctccc
      601 atcatgccat ggactggccc tattgggcca caccactgga gctcagtaaa agctgctgtt
      661 tggttaaaaa
//
