LOCUS       NM_001134558            2632 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus UV-stimulated scaffold protein A (Uvssa), mRNA.
ACCESSION   NM_001134558 XM_001065721 XM_234083
VERSION     NM_001134558.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2632)
  AUTHORS   Zhang,X., Horibata,K., Saijo,M., Ishigami,C., Ukai,A., Kanno,S.,
            Tahara,H., Neilan,E.G., Honma,M., Nohmi,T., Yasui,A. and Tanaka,K.
  TITLE     Mutations in UVSSA cause UV-sensitive syndrome and destabilize
            ERCC6 in transcription-coupled DNA repair
  JOURNAL   Nat Genet 44 (5), 593-597 (2012)
   PUBMED   22466612
REFERENCE   2  (bases 1 to 2632)
  AUTHORS   Schwertman,P., Lagarou,A., Dekkers,D.H., Raams,A., van der
            Hoek,A.C., Laffeber,C., Hoeijmakers,J.H., Demmers,J.A.,
            Fousteri,M., Vermeulen,W. and Marteijn,J.A.
  TITLE     UV-sensitive syndrome protein UVSSA recruits USP7 to regulate
            transcription-coupled repair
  JOURNAL   Nat Genet 44 (5), 598-602 (2012)
   PUBMED   22466611
REFERENCE   3  (bases 1 to 2632)
  AUTHORS   Nakazawa,Y., Sasaki,K., Mitsutake,N., Matsuse,M., Shimada,M.,
            Nardo,T., Takahashi,Y., Ohyama,K., Ito,K., Mishima,H., Nomura,M.,
            Kinoshita,A., Ono,S., Takenaka,K., Masuyama,R., Kudo,T., Slor,H.,
            Utani,A., Tateishi,S., Yamashita,S., Stefanini,M., Lehmann,A.R.,
            Yoshiura,K. and Ogi,T.
  TITLE     Mutations in UVSSA cause UV-sensitive syndrome and impair RNA
            polymerase IIo processing in transcription-coupled
            nucleotide-excision repair
  JOURNAL   Nat Genet 44 (5), 586-592 (2012)
   PUBMED   22466610
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473963.1.
            
            On or before Sep 4, 2008 this sequence version replaced
            XM_234083.4, XM_001065721.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2632
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..2632
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /note="UV-stimulated scaffold protein A"
                     /db_xref="GeneID:314061"
                     /db_xref="RGD:1306371"
     exon            1..447
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
     exon            448..547
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
     CDS             450..2594
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /codon_start=1
                     /product="UV-stimulated scaffold protein A"
                     /protein_id="NP_001128030.1"
                     /db_xref="GeneID:314061"
                     /db_xref="RGD:1306371"
                     /translation="MDQKLSQLIEELTTSGESQLNAQKMKELKKICKSSEEQLSHAYR
                     LLMTQLTQDHAEIRLSAFQIVDELFTRSHQFRVLLVSDFQEFLELTLGTDNDHPLPPP
                     REAAQRLRQAAMQAVEGWNEKFGEAYKKLALGYHFLKHTKKVDFRDINVRTLAERKRE
                     EEKQKHLDKIHRESADRAKREMEEMSDEIGCCLTEVENCFRLLVPLDLGPYREDKFFG
                     EASGIAEDHAPCAWSPDLATPRGSGLSGPQDEEQPCCSKDLVASAHHAGSAVGLKAPA
                     PAATEDPCRDEDRHSEHSDPEDFLRSHGLGSHKYTLDVELPSDGLKVQENEDNLAVLH
                     AARDSLKLIQNKFLPAVCSWVQRFTRAGIYSGHLKQAIDLKMELELALKKYEELNIEP
                     GRGQRSRTEALEDSEEEDQDFVEVPEKEGYEPRIPDHLRAEYGLEPKAPLKTLEKHTA
                     VCSVQERTRRRREEEASDPTSAAAQMLRLQDCLSSPSSSSTRGPLGPEEAQKQAERAR
                     APMVPFGVDLCYWGQEQLTAGKILKSDSQHRFWKPHEVEEEVDSAHVSEMLHSRHITF
                     SGKFEPVQHKCRALRPNGRLCERQDRLKCPFHGKIIPRDDKGQPLNPEDRAREQRQQL
                     QQQRAHPDWQDPEFMKDVEAATGVDLGSSKYSKKGKGKKKKHPNLTDLRERANTARAR
                     LEKKVFAKSCAESSCCHEPDGPEEAREVCKSI"
     exon            548..878
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
     exon            879..999
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1404
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
     exon            1405..1517
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
     exon            1518..1646
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
     exon            1647..1752
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
     exon            1753..1924
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
     exon            1925..2047
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
     exon            2048..2231
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
     exon            2232..2343
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
     exon            2344..2518
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
     exon            2519..2632
                     /gene="Uvssa"
                     /gene_synonym="RGD1306371"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgtggagcca cccgggcaaa tgcgggagac tggtggtggc ctaatctgaa aggaccagag
       61 cgggcgcgcc gcggtaactt ccgctcctgc gccgcgggtc ttctggagtt tgtgcccgcc
      121 gctccctggg gcctgtaaca gagcgctgcc tacaccggaa ggggtgggtg agacaagagg
      181 ctgcatccgg tggtccgtgt caccggaaca gcggaacgct ggtactgtct cctgaagcgg
      241 agggtcaggc agcgattgcg gcggactgaa gggtcgtggc cggtcagatt ctcggcccgc
      301 agggtcggat cggtcgcccc cgcagttatc tagagactgt cgcttgcaga gagagagtat
      361 cctgtgcgac cagttggagt aaaatttagt gacatttccc cttaaccgcg gcagcgtcac
      421 ccacacagct gacctaagac tgctggaata tggatcagaa actttcacag ttgatagagg
      481 agctcacaac ttcaggagaa tcccaactga atgctcagaa aatgaaggaa ctgaagaaaa
      541 tttgcaagtc ttcagaggag cagctgagcc atgcctaccg cctgctaatg acacagctga
      601 cccaggacca cgctgagatc cgcctctcag ccttccagat cgtggatgag ctcttcaccc
      661 ggtcccatca gttcagagtg ctgcttgttt ctgacttcca ggaattcctg gagctcacac
      721 tgggcacaga caatgaccat cccttgccac cccctcggga ggcagctcag aggctaaggc
      781 aggcagccat gcaagctgtg gaaggttgga atgagaagtt tggggaagcc tataagaagc
      841 tagccttggg ctaccacttc ctaaaacaca ccaaaaaggt ggattttcgg gatataaatg
      901 ttaggactct ggcagaaagg aagcgagaag aggagaagca gaagcacttg gataagatcc
      961 acagagaaag tgctgaccgg gctaagaggg agatggaaga aatgtctgat gaaattggat
     1021 gctgcctgac agaagtggag aactgcttta ggctgctggt gcccttggat ttgggcccgt
     1081 accgagagga taagttcttt ggtgaggcat ctggcatagc agaggaccat gctccttgcg
     1141 cctggagccc agacctggca actccccgag ggtctggtct ctctggaccc caggatgaag
     1201 agcagccatg ctgtagcaag gacctggttg cctctgcaca ccatgcagga tctgcagttg
     1261 gtctgaaggc accagcccca gcagccacgg aagacccctg cagggatgaa gacagacaca
     1321 gcgaacacag cgacccagag gatttcctgc ggagccatgg gctgggctcc cacaagtaca
     1381 cgctggacgt ggaactcccc tcagacggtc tgaaggtaca ggagaatgaa gacaacctgg
     1441 ccgtgctcca cgctgctcga gactcgctca aactcatcca gaacaagttt ctgccagcgg
     1501 tgtgctcctg ggtccagcgg tttacccgtg cagggatcta cagtggacat ttaaagcagg
     1561 ccattgacct gaaaatggaa ctggaacttg ctctgaagaa atatgaagaa ctgaacattg
     1621 agcctgggag aggacaaagg agcaggacag aagcactgga ggacagtgag gaggaggacc
     1681 aggacttcgt ggaggttcca gagaaagagg gttacgagcc tcgaatcccc gaccatctac
     1741 gagctgaata tgggctggag ccaaaggccc cactgaagac tctggagaaa catacagctg
     1801 tatgtagcgt acaggagagg accaggagga gaagggaaga ggaggcctca gaccccacct
     1861 ctgcagctgc ccagatgttg cggctccagg actgcttgtc atctccctcc tcctcctcta
     1921 ccaggggacc tctgggacca gaagaagccc agaagcaagc ggagcgagcc cgagcaccca
     1981 tggtgccctt cggagtggac ctgtgctact ggggccagga gcagctaaca gctgggaaga
     2041 ttcttaaatc cgactctcaa caccgcttct ggaaacccca cgaggtagag gaagaggtgg
     2101 acagtgccca tgtttctgag atgctccaca gccgacacat taccttttct gggaaattcg
     2161 agcctgtgca gcacaagtgc cgggccctca ggcctaatgg caggctctgc gagcgccagg
     2221 atcggctgaa gtgcccgttc catgggaaga tcatccccag agatgacaag gggcagcctc
     2281 tcaaccctga agacagagcc cgtgaacaga ggcagcagct tcagcagcaa cgggcacatc
     2341 cagattggca ggaccctgag tttatgaagg acgtggaggc agccacaggg gtggacctcg
     2401 gttcctccaa gtatagcaag aagggcaaag ggaaaaagaa gaagcacccc aacctcactg
     2461 accttcgaga acgtgccaac actgcccgag cccgccttga gaagaaggtc tttgccaaga
     2521 gctgtgcaga gagtagttgc tgccatgaac cagatggacc agaagaagca cgagaagttt
     2581 gcaaatcaat ttaattatgc actgaagtaa aagggtgtgg gtgtggcgaa tg
//
