LOCUS       NM_001419832            7153 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus ubiquitously transcribed tetratricopeptide repeat
            containing, Y-linked (Uty), transcript variant 2, mRNA.
ACCESSION   NM_001419832
VERSION     NM_001419832.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7153)
  AUTHORS   Gao,Y.B., Chen,Z.L., Li,J.G., Hu,X.D., Shi,X.J., Sun,Z.M.,
            Zhang,F., Zhao,Z.R., Li,Z.T., Liu,Z.Y., Zhao,Y.D., Sun,J.,
            Zhou,C.C., Yao,R., Wang,S.Y., Wang,P., Sun,N., Zhang,B.H.,
            Dong,J.S., Yu,Y., Luo,M., Feng,X.L., Shi,S.S., Zhou,F., Tan,F.W.,
            Qiu,B., Li,N., Shao,K., Zhang,L.J., Zhang,L.J., Xue,Q., Gao,S.G.
            and He,J.
  TITLE     Genetic landscape of esophageal squamous cell carcinoma
  JOURNAL   Nat Genet 46 (10), 1097-1102 (2014)
   PUBMED   25151357
REFERENCE   2  (bases 1 to 7153)
  AUTHORS   Cortez,D., Marin,R., Toledo-Flores,D., Froidevaux,L., Liechti,A.,
            Waters,P.D., Grutzner,F. and Kaessmann,H.
  TITLE     Origins and functional evolution of Y chromosomes across mammals
  JOURNAL   Nature 508 (7497), 488-493 (2014)
   PUBMED   24759410
REFERENCE   3  (bases 1 to 7153)
  AUTHORS   Vieira,F.Q., Costa-Pinheiro,P., Ramalho-Carvalho,J., Pereira,A.,
            Menezes,F.D., Antunes,L., Carneiro,I., Oliveira,J., Henrique,R. and
            Jeronimo,C.
  TITLE     Deregulated expression of selected histone methylases and
            demethylases in prostate carcinoma
  JOURNAL   Endocr Relat Cancer 21 (1), 51-61 (2013)
   PUBMED   24200674
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7153)
  AUTHORS   Henriquez,B., Bustos,F.J., Aguilar,R., Becerra,A., Simon,F.,
            Montecino,M. and van Zundert,B.
  TITLE     Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in
            developing hippocampal neurons
  JOURNAL   Mol Cell Neurosci 57, 130-143 (2013)
   PUBMED   23932971
REFERENCE   5  (bases 1 to 7153)
  AUTHORS   Komers,R., Mar,D., Denisenko,O., Xu,B., Oyama,T.T. and Bomsztyk,K.
  TITLE     Epigenetic changes in renal genes dysregulated in mouse and rat
            models of type 1 diabetes
  JOURNAL   Lab Invest 93 (5), 543-552 (2013)
   PUBMED   23508046
REFERENCE   6  (bases 1 to 7153)
  AUTHORS   Audenet,F., Yates,D.R., Cancel-Tassin,G., Cussenot,O. and
            Roupret,M.
  TITLE     Genetic pathways involved in carcinogenesis of clear cell renal
            cell carcinoma: genomics towards personalized medicine
  JOURNAL   BJU Int 109 (12), 1864-1870 (2012)
   PUBMED   22035299
  REMARK    Review article
REFERENCE   7  (bases 1 to 7153)
  AUTHORS   Lee,S., Lee,J.W. and Lee,S.K.
  TITLE     UTX, a histone H3-lysine 27 demethylase, acts as a critical switch
            to activate the cardiac developmental program
  JOURNAL   Dev Cell 22 (1), 25-37 (2012)
   PUBMED   22192413
REFERENCE   8  (bases 1 to 7153)
  AUTHORS   Patani,N., Jiang,W.G., Newbold,R.F. and Mokbel,K.
  TITLE     Histone-modifier gene expression profiles are associated with
            pathological and clinical outcomes in human breast cancer
  JOURNAL   Anticancer Res 31 (12), 4115-4125 (2011)
   PUBMED   22199269
REFERENCE   9  (bases 1 to 7153)
  AUTHORS   Wilson,B.G. and Roberts,C.W.
  TITLE     SWI/SNF nucleosome remodellers and cancer
  JOURNAL   Nat Rev Cancer 11 (7), 481-492 (2011)
   PUBMED   21654818
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   10 (bases 1 to 7153)
  AUTHORS   Pink,C.J., Swaminathan,S.K., Dunham,I., Rogers,J., Ward,A. and
            Hurst,L.D.
  TITLE     Evidence that replication-associated mutation alone does not
            explain between-chromosome differences in substitution rates
  JOURNAL   Genome Biol Evol 1, 13-22 (2009)
   PUBMED   20333173
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000022.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643289.45465.1,
                                           SRR26360190.1123403.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-509               JAXUCZ010000022.1  1177847-1178355     c
            510-573             JAXUCZ010000022.1  1177597-1177660     c
            574-682             JAXUCZ010000022.1  1171137-1171245     c
            683-732             JAXUCZ010000022.1  1147929-1147978     c
            733-791             JAXUCZ010000022.1  1123751-1123809     c
            792-912             JAXUCZ010000022.1  1121243-1121363     c
            913-967             JAXUCZ010000022.1  1116165-1116219     c
            968-1002            JAXUCZ010000022.1  1113069-1113103     c
            1003-1096           JAXUCZ010000022.1  1098529-1098622     c
            1097-1223           JAXUCZ010000022.1  1097168-1097294     c
            1224-1322           JAXUCZ010000022.1  1083454-1083552     c
            1323-1542           JAXUCZ010000022.1  1082600-1082819     c
            1543-1677           JAXUCZ010000022.1  1081782-1081916     c
            1678-1773           JAXUCZ010000022.1  1080617-1080712     c
            1774-2507           JAXUCZ010000022.1  1068860-1069593     c
            2508-2637           JAXUCZ010000022.1  1064633-1064762     c
            2638-2743           JAXUCZ010000022.1  1062815-1062920     c
            2744-2949           JAXUCZ010000022.1  1061903-1062108     c
            2950-3014           JAXUCZ010000022.1  1044090-1044154     c
            3015-3089           JAXUCZ010000022.1  1043942-1044016     c
            3090-3238           JAXUCZ010000022.1  1043393-1043541     c
            3239-3353           JAXUCZ010000022.1  1041760-1041874     c
            3354-3541           JAXUCZ010000022.1  1036973-1037160     c
            3542-3683           JAXUCZ010000022.1  1036010-1036151     c
            3684-3810           JAXUCZ010000022.1  1025343-1025469     c
            3811-3981           JAXUCZ010000022.1  1022329-1022499     c
            3982-7153           JAXUCZ010000022.1  1018111-1021282     c
FEATURES             Location/Qualifiers
     source          1..7153
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="Y"
                     /map="Yq11"
     gene            1..7153
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /note="ubiquitously transcribed tetratricopeptide repeat
                     containing, Y-linked"
                     /db_xref="GeneID:100310845"
                     /db_xref="RGD:1565481"
     exon            1..509
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     CDS             421..4008
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /EC_number="1.14.11.68"
                     /note="ubiquitously transcribed tetratricopeptide repeat
                     gene, X chromosome; ubiquitously transcribed
                     tetratricopeptide repeat, X chromosome; lysine
                     (K)-specific demethylase 6A; lysine demethylase 6A;
                     histone demethylase UTY; ubiquitously transcribed
                     tetratricopeptide repeat gene, Y chromosome; histone
                     demethylase UTY-like"
                     /codon_start=1
                     /product="lysine-specific demethylase 6A"
                     /protein_id="NP_001406761.1"
                     /db_xref="GeneID:100310845"
                     /db_xref="RGD:1565481"
                     /translation="MAAEKARGEGEEGSFSLTVEEKKALCGLDSSFFGFLSLCKDGVK
                     MKTLLNKAIHCYESLIVKAEGKVESDFFCQLGHFNLLLEDYSKALSSYQRYYSLQTDY
                     WKNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLRLGFMFKVNTDYE
                     SSLKHFQLALRDSNVCTLSSVEIQFHIAHLFEIQRKYHSAKAAYEQLLQIESLPSQVK
                     ATVLQQLGWMHHNMDLVGDNTTKERYAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKV
                     QDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDL
                     GILYESCNQTQDAIKCYLNATRSKSCSNTSVLISRIKFLQAQLCNLPQSSLQNKTKLL
                     PSIEEAWSLPIPAELTSRQGAMNTAQQNVSDSWNSVHTASHHPVQQQVYTQCFTTQKL
                     QGLGKDQQRPFQTGSTRYIHAACVDNQNQNGNHTLPQNSKGDTQNHSSLHIPTSEEQK
                     IFNFTKESKDSRSKSLSPKTSRQDRDTSNIYVNAKEHSKNIHEITSVPISSLNNEDSV
                     SPNLIIVDNPQLSVLVGEAMDSVDHDSRTCDKVNNVHPTLHKKPDNLTASSPSSASST
                     ETLSLKVTEQMHTHIVTSFISPNSGLDTINGGPENSESSISVSVGLRPRPQIIPSMSV
                     SIYSSSTEVLKACRNLGKNGLSNGHILLDICPPPRPPTSPYPPLPKEKLNPPTPSIYL
                     ENKRDAFFPPLHQFCINPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHIVEVRTQ
                     FLQPADENWDPSGTKKIWRYENKSSHTTIAKYAQYQACSFQESLREENERKTQVKDYS
                     DNESTCSDISRRRQKVPFKTIKCGINIDLSDNKKWKLQLHELTKLPAFVRVVSAGNLL
                     SHVGYTILGMNSVQLCMKVPGSRIPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVL
                     NDFCEKNNLNFLMSSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCN
                     NITWNVGPLTAFQYKLAVERYEWNKLQSIKSVVPMVHLSWNMARNIKVSDPKLFEMIK
                     YCLLKILKQCQTLREALVAAGKEVLWHGRINDEPAPYCSICEVEVFNLLFVTNESNSQ
                     KTYIVHCQNCARKTSGNLENFVVLEQYKMEDLIQVYDQFTLAPSLSSSS"
     exon            510..573
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            574..682
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            683..732
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            733..791
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            792..912
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            913..967
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1002
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1096
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1223
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1224..1322
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1323..1542
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1543..1677
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1678..1773
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            1774..2507
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            2508..2637
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            2638..2743
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            2744..2949
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            2950..3014
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3015..3089
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3090..3238
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3239..3353
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3354..3541
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3542..3683
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3684..3810
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3811..3981
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
     exon            3982..7153
                     /gene="Uty"
                     /gene_synonym="Kdm6a; RGD1565481; Utx"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtttccattg gaaagcctgg ctttaggaag aggttatggc ctctgtgtgc ggttcacact
       61 gactcgatta taacaacttt atgcagatgc cagtgaagtt tgatattcta agaatctcgg
      121 gtaggttctg caacaatgcc tgcctcttgc gttcatcacc tgcgtgataa tgtgaccaga
      181 tagcttctgc cgctttctcc tttgccacgg agtttatcgt ggcccacagc ggcgcccaca
      241 actgcggcgg taaagttggc atggtggttt caagcaacga ttgaagctat catttcaaaa
      301 gaagatctgg attgttagtg gtggtgagcc tagacgtgga acttagactt tttttacatt
      361 tccgtgaaat catacggatt gtctctcact actgctgtcc taggtaatga ggaaaagaaa
      421 atggcggcgg aaaaggctag aggcgagggc gaagaggggt ccttcagtct cacagtcgaa
      481 gagaagaagg cgctttgtgg attagacagc agcttcttcg ggttcttgag cctatgcaaa
      541 gatggcgtca agatgaagac gctgttgaac aaggcaattc attgctatga atctttaata
      601 gtaaaagctg aaggaaaagt ggaatcagat ttcttttgtc aattaggtca cttcaatctc
      661 ttactggaag attattcaaa agcattgtca tcttaccaga gatactacag tttacagact
      721 gactactgga agaatgctgc atttttatat ggtcttggtt tggtctactt ctactacaat
      781 gcatttcaat gggcaattag agcatttcaa gaagtccttt atgttgaccc taatttttgc
      841 agagccaagg aaattcattt acgacttggc tttatgttca aagtaaatac agattatgag
      901 tctagtttaa agcattttca gctggctcta agggactcta atgtctgtac cttgtccagt
      961 gttgaaattc agtttcatat tgctcactta tttgaaattc agaggaaata ccattctgca
     1021 aaagcagcct atgaacaact tttacaaatt gaaagccttc catcacaagt caaagcaact
     1081 gtattgcaac agttaggttg gatgcaccat aatatggatc tagtaggaga caataccacc
     1141 aaagaaagat atgccattca gtatcttcaa aagtcattgg aggaagatcc taattctggc
     1201 caatcttggt atttccttgg aaggtgttac tcgtgtattg ggaaagttca ggatgccttt
     1261 gtatcttata ggcaatccat tgataaatca gaagcaagtg cagacacatg gtgttcaata
     1321 ggtgtgcttt atcaacagca aaatcaacct atggatgcct tgcaagctta tatatgtgct
     1381 gtacagttag atcatggaca tgcagcagcc tggatggact taggtattct ttatgaatcc
     1441 tgcaaccaaa cccaggacgc cattaaatgc tacttaaatg caactcggag caaaagctgt
     1501 agtaacacct ctgtgcttat atcaagaatt aagtttttac aggctcagtt gtgtaacctt
     1561 ccacaaagta gtctacagaa taaaactaaa ttacttccta gtattgagga ggcatggagc
     1621 ctaccaatcc ccgcagagct tacctccagg cagggtgcca tgaacacagc acagcagaat
     1681 gtttctgata gctggaatag tgtccacaca gcttcacatc atccagtaca gcagcaagtt
     1741 tatacacagt gcttcacaac acagaaatta cagggtcttg gtaaagatca acaacgtccg
     1801 tttcaaactg ggtctacacg gtatatccat gcagcttgcg ttgataatca gaatcagaat
     1861 ggaaatcata ctttgcctca aaattcaaag ggggatactc aaaaccactc ttccttacat
     1921 attcctacct cagaagaaca aaagatcttt aactttacca aagagagcaa ggattcaaga
     1981 agtaaatcct tgagtcctaa aacaagtagg caagatagag acacatctaa tatctatgtt
     2041 aatgcaaagg aacattctaa aaatattcat gagatcacat cagttcctat ttccagtctt
     2101 aataatgaag attctgtgtc accaaattta ataattgtag ataatcctca gctttctgtc
     2161 ttggtaggag aagctatgga cagtgtggac catgactcta gaacttgtga caaagtcaat
     2221 aatgttcatc caacccttca caaaaagcct gataatctta ctgcttcttc accctcttca
     2281 gccagttcca cagaaacact ttctctaaag gtcactgagc agatgcacac acacattgtt
     2341 accagcttta tcagccctaa cagtggatta gacacaatta atggaggacc tgagaactca
     2401 gaaagttcta tcagtgttag tgttggcctc agacctagac ctcaaatcat accatcgatg
     2461 tctgtgtcca tatactcgag ttcaacagaa gttctgaaag catgcaggaa tctaggtaaa
     2521 aatggtttgt caaatggtca tattctcttg gatatatgcc cacctccaag accaccaact
     2581 tcaccatacc ctcccttacc aaaagagaag ttgaatccac ccactcctag tatttatttg
     2641 gaaaataagc gtgatgcctt tttccctcca ttacatcaat tttgcatcaa tccaaaaaac
     2701 cctgttacgg taattcgtgg ccttgctgga gctcttaagt tagatcttgg acttttctct
     2761 accaaaactt tggtagaagc taacaatgag catatcgtag aagtgaggac ccaatttttg
     2821 cagccagcag atgaaaactg ggatccttct ggaacaaaga aaatctggcg gtatgaaaat
     2881 aaaagttctc atactacaat tgctaaatat gcacagtacc aggcctgctc cttccaggaa
     2941 tcattgagag aagaaaatga gagaaaaaca caagttaaag actattcaga taatgaatca
     3001 acatgttcag atatttccag aaggagacag aaagtacctt ttaaaaccat aaaatgtggc
     3061 attaacattg acctgtctga taacaaaaag tggaagttgc agttacatga gctgactaag
     3121 cttcctgctt ttgtacgtgt tgtatcagca gggaatcttc tcagtcatgt tggctatacc
     3181 atactgggaa tgaattcagt tcaactttgt atgaaagttc cagggagtag gataccaggt
     3241 caccaagaaa ataacaactt ctgttctgtt aacataaata ttggtccagg tgattgtgaa
     3301 tggtttgttg tacctgaaga ttattggggt gttctgaatg acttctgtga aaaaaataat
     3361 ttgaatttct tgatgagttc ttggtggccg aaccttgaag atctttatga agcaaatgtt
     3421 cctgtttata ggtttattca aagacctgga gatttggtct ggataaatgc aggcactgtt
     3481 cactgggttc aggctattgg gtggtgtaac aacatcacct ggaatgttgg tccactcaca
     3541 gccttccagt ataaattggc agttgaaaga tatgaatgga acaaattgca aagtatcaag
     3601 tcagtagtac ccatggttca tctttcatgg aatatggcac gaaatatcaa agtctcagat
     3661 ccaaagcttt ttgaaatgat taaatattgt ctcctcaaga ttctaaagca gtgtcaaact
     3721 ttgagagaag ctcttgttgc agcagggaaa gaggttttgt ggcacggaag gataaatgat
     3781 gaaccagctc cttactgtag catctgtgag gtggaagttt ttaatttgct ttttgtcaca
     3841 aatgaaagca attctcaaaa gacatacata gtacattgtc agaactgtgc acgaaaaaca
     3901 agtgggaatc tggaaaattt tgtggtgcta gaacagtaca aaatggagga tctgattcaa
     3961 gtctatgacc agtttacatt agctccttca ttatcttctt catcttaaca ttgttccaaa
     4021 aatactaaga ctcttcgtga aatatactac tcatcttaat gttatttcat atgagactgc
     4081 tatctcaaag ctgtctatgc accctttcaa gagtagaaaa tcaggagact aagcagaaag
     4141 cattacttct attccaagat ttgcaaagtt gacccaaatg tatttcataa ttaaaaatta
     4201 atagtaatac cacatgattt gtatatatct cacagaaatg ccattttcac aaagactaat
     4261 ggcttgaaaa caaccctttt tatgtctgca tttctgggct gatggattga tttctttatg
     4321 cttgtaagtt accctttcaa attttttctt cagaatcaaa tagcatctta cttggctact
     4381 tcttttcaag acaactaaca aattaaaaaa cttttttttg ccaattttta tctaaaacca
     4441 aaataatatg aaaatgttta taatgctctg tcactattgt tttgaagtca caaaacatta
     4501 acaaccaagg taaaaagatt ataggttgca tataaataat ttcatatttg tggtttttta
     4561 tttgttttta atattgacac aaacttaaac tatttatata tgtatattgc ttgaaaatac
     4621 ttgtggattg aatgttattt ttcctagatt cccttgccat taaatattaa gaagttgtgt
     4681 aattttaaat gccacaatta aattttctat gtgtaaatag agctacttaa cattgtacat
     4741 aaacttttat taaaattgtt gagtgtttaa aggattttgc aatgtttgag ttttgaagac
     4801 tatatagatc cactctttgt tctttttaaa aactaatgaa tatatgtatt ttatgtgtct
     4861 gtaaacacat gtattatatg tagaaatctc aatatttcac gctacaagga aatccaaatt
     4921 tttcaacttt tttatgtctg atagtttttg aaggtatttg tttacaaaat atgtatgctt
     4981 atttttaaag accataagta tcttttagtc tgattaggtt gcatcttata caatgacaac
     5041 tagtaagtag ttgctgtcag aaatattttt taagggcaga aaaaaaagtt aaattaagtt
     5101 ttttataaga tacatataga tttgacaaat gcttatcatt tagaattttg ctttaataga
     5161 aaagttaatt ggaatgataa cctctatttt agagtattaa tatacttttt taaaagttag
     5221 ataattttaa aattccatgt gttcctgctt atgtgttgtt gggagacaaa ggcattaaaa
     5281 tttgttattc gtaaatctta acaaggtcta tgaagacttt atttcatatt taaaaattta
     5341 cttttttact tacaagctta gttttacagt ttaacaaaaa acattcctat tttcttctga
     5401 tttttgaagt attagcctta cattctcatt ttattatttg tactttccaa agtgtttttc
     5461 taagaatttt attgaagaat tgatgaagca ttctaagtga agtcaaatta caaattttta
     5521 tttcttggtg gtaagctagc ttgattgaat tatgatgttt cctatatagt ttgaaatatg
     5581 tcatcataga aataaaagag tcataaatat atatatatta ttaaacaact tgcaagtact
     5641 catggttagt gactattata taagaaagaa attgttataa ttttttgtta aaggatatgt
     5701 agtaagcgtg tgatgaaatg atttagtaga taaagcactt gctttgaaat cctgccaact
     5761 taattaagat tggtccctgg accctatgtt cacgtaggag aaaactgact ccagtgagct
     5821 atcccctgag ttaatactta tgccacaaaa ttaatgttac actcaacaca tacaaatgta
     5881 aacagtataa aatattaaat gatactgtgt gttttaagtg gctaaattct ttcattttct
     5941 gaaatccagt tcaaaggctg tagcaagaaa aatccttatt tttaaacaaa ttgcaaatca
     6001 gtcaagagaa aataaagatt tttgtattat atacaaaatt ttttcttatt tgctctgatt
     6061 tacattactt aatcttattg ttatcttaaa ttattcaaag ttaggtcatt tcaagatcag
     6121 cataaattta gcttaatgga tttatttaga attcaaaaag gagttagttt ttattgactg
     6181 caattatatg aaacaacact tagagataaa aagagagaga ctacagcaga caccaaggaa
     6241 attcagaaaa atctaaggat atacttgaaa attttttact ccagtaagct aaaaaaaact
     6301 ttaaatttgt attggaaatt ttctttaaat atatatttat aggagaataa gttccctgat
     6361 acttacatta aaaaccaggt gtagtggtac acacttttaa catcagtcta gaagaaactt
     6421 atttttgatg tctaaataaa tccactaagt taaatttaaa ttttgaaaaa tttaagacaa
     6481 caataaatta agtaatgcaa atcagaacaa ataacaaatt tttgtatgca ataatcatta
     6541 tattctattg gctgatttgt agtctgtttg aaaataagat ttttcttgct taaaccattg
     6601 aactgatttt ctgggctttg cttgatagct aatctggccg tttggcaaac aaggtgatag
     6661 ctcctgcaga ataccagggt tgacctctga cctctacaag cagtcctata caagtgtaca
     6721 tccattatta tctttttaca gtattcttcc tgcatgtatg cctgtactcc agaaaagggt
     6781 acagatctca ttacagatgg atataaacta ccatgtagtt gttggggatt gaactcaaga
     6841 cctttggaag aacagtcagt gctcttaacc tgtaagctat cttatagccc cttgaaacat
     6901 tttcttaaac acatcacaga aaagtatgtt tggtataact aagatgacat caaacgttca
     6961 gatttttctt gctatgagaa ttggtacagt tgactgtttt taaacaagaa tgtatgatgg
     7021 aatatataaa aaatatgtag actatatagc atactctgtg tgctgtatat gttttataga
     7081 gaaatatttc tttatacaga aattcaagac aagtgtctgc acaaatttac ataaacataa
     7141 acaaccgttt cta
//
