LOCUS       NM_001013986            2668 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus UTP25 small subunit processome component (Utp25),
            mRNA.
ACCESSION   NM_001013986 XM_223085
VERSION     NM_001013986.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2668)
  AUTHORS   Aryal,N.K., Wasylishen,A.R., Pant,V., Riley-Croce,M. and Lozano,G.
  TITLE     Loss of digestive organ expansion factor (Diexf) reveals an
            essential role during murine embryonic development that is
            independent of p53
  JOURNAL   Oncotarget 8 (61), 103996-104006 (2017)
   PUBMED   29262616
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2668)
  AUTHORS   Tao,T., Shi,H., Guan,Y., Huang,D., Chen,Y., Lane,D.P., Chen,J. and
            Peng,J.
  TITLE     Def defines a conserved nucleolar pathway that leads p53 to
            proteasome-independent degradation
  JOURNAL   Cell Res 23 (5), 620-634 (2013)
   PUBMED   23357851
REFERENCE   3  (bases 1 to 2668)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB569988.1 and BC087114.1.
            
            On Sep 15, 2005 this sequence version replaced NM_001013986.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087114.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                CB569988.1         13-58
            47-2668             BC087114.1         1-2622
FEATURES             Location/Qualifiers
     source          1..2668
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q27"
     gene            1..2668
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /note="UTP25 small subunit processome component"
                     /db_xref="GeneID:305076"
                     /db_xref="RGD:1359148"
     exon            1..200
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /inference="alignment:Splign:2.1.0"
     CDS             94..2385
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /note="novel putative protein similar to YIL091C yeast
                     hypothetical 84 kD protein from SGA1-KTR7; UTP25, small
                     subunit processor component"
                     /codon_start=1
                     /product="U3 small nucleolar RNA-associated protein 25
                     homolog"
                     /protein_id="NP_001014008.1"
                     /db_xref="GeneID:305076"
                     /db_xref="RGD:1359148"
                     /translation="MGKRRSRGRSQLLSTMTKKQKKHLRDFGEEHPFYDRVSKKEVKP
                     QICQLSESSDSSHSESESESEQEHVSGYHRLLATLKNISEEEEEEEEEEEEEEEDKEE
                     VDDSAVGDSEMNGEDGGEDVRVEETAESSETQDHMSLADNSKGKDGEEPPGVSQKSSE
                     EFTDVKHESLFSLETNFLEEESGGSYSQRTSQDPFQHHINKELQEKEIQAAASSPAAT
                     QQLKWPVLGHLVFSSKFQKMETFKPPKDIDLKSLHLQKPLESTWAKTNSQFLSGPGPQ
                     KSSSCFTPLQKELFLIMNSYRDLFYPERTALKNGEEVRHVYCLHAINHVLKANAQVLA
                     NNSRRRTQKLGVGDDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEGDSKKKII
                     VSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFY
                     SSDILIASPLGLRTIIGGEGEKKRDFDFLSSIELLIIDQADIYLMQNWEHVLHLMNHM
                     NLLPLDSHGVNFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKHCVNAQGQVAV
                     RNVPMTGSISHVLVQLPHVFQRMEAQDLASVIDARFHFFINKILPQYRDAVMSHTLIY
                     VPSYFDFVRLRNYFKKEELNFTHICEYTQRSGVSRARHFFLQGEKQFLLLTERFHFYK
                     RYTIKGIRNLIFYELPTYAHFYSEVCNMLRATSRGEEATWTCTVLYSKYDAQRLAAVV
                     GVERAAQMLQSPKSVHLFITGEK"
     exon            201..240
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /inference="alignment:Splign:2.1.0"
     exon            241..499
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /inference="alignment:Splign:2.1.0"
     exon            500..670
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /inference="alignment:Splign:2.1.0"
     exon            671..759
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /inference="alignment:Splign:2.1.0"
     exon            760..1176
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1396
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1599
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /inference="alignment:Splign:2.1.0"
     exon            1600..1782
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /inference="alignment:Splign:2.1.0"
     exon            1783..1895
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /inference="alignment:Splign:2.1.0"
     exon            1896..2141
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /inference="alignment:Splign:2.1.0"
     exon            2142..2643
                     /gene="Utp25"
                     /gene_synonym="Def; Diexf"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggcgtacc cacgtgcgac aacttcccac tggaaacctt gggtttggtt gttgtgtttt
       61 ttatgttgtg gtgggaagct tgacgtttcc gctatgggca aacgccggag tcgtggccgc
      121 agccagctgc tcagcacaat gaccaagaag cagaagaagc acctccgcga cttcggcgag
      181 gagcacccct tctacgacag ggtttccaag aaggaagtca agccgcaaat ttgtcagctg
      241 tcagagagct cagattcttc acattctgaa agtgaatcag agagtgaaca agagcatgtt
      301 tcggggtacc acagactgct tgctacatta aagaacattt ctgaggagga ggaggaagag
      361 gaggaagaag aagaggagga ggaggaagac aaagaggagg tggatgacag tgctgtaggt
      421 gattcggaaa tgaatggtga agatggcggt gaggatgtcc gtgtggaaga aactgcagag
      481 tcctctgaga cacaggacca tatgtctcta gctgacaact caaaaggaaa agatggtgaa
      541 gagccacctg gtgtatcaca gaaatcttca gaggagttca cagatgtgaa acacgagtca
      601 ctgttcagcc tggaaaccaa ttttctagaa gaggagagtg ggggcagtta ttcccagaga
      661 acatcccaag atccatttca acatcacatc aacaaagaac tgcaagaaaa ggaaattcaa
      721 gccgctgcct caagccctgc agctacccag caactgaaat ggccagtcct gggacatctt
      781 gtcttttcat caaagttcca gaagatggaa acatttaaac ctccaaagga tattgaccta
      841 aagtcacttc atcttcagaa gcccctagaa tccacctggg caaaaaccaa cagccaattt
      901 ctatctggtc ctggtcctca aaaatcaagt agctgcttta ccccactcca gaaagagctg
      961 ttcttgatta tgaattctta ccgggacctg ttctaccctg agaggactgc cctgaagaat
     1021 ggagaagaag tccgccatgt gtactgcctg catgccataa accacgtcct caaagccaat
     1081 gctcaagtgc tggctaacaa cagcaggcgc cggacccaga aactcggggt gggtgacgat
     1141 gatgacttca gggaccaggg gctcaccagg cccaaggtac ttatagtggt gcctttccgg
     1201 gaagctgccc ttcgggtggt ccagctcttc atcagcctcc ttgaggggga cagcaagaag
     1261 aaaatcattg taagcaataa aaagaggttt cagggggaat atggatctga ccctgaggag
     1321 agacctccca acctgaagag gcctgaggat tatgaagctg tgttcgtggg caatattgat
     1381 gaccacttca ggattggagt ggcgatactt cagaggagca tccgtctcta cgccccgttt
     1441 tactcctctg acatcctcat tgcctccccc ctgggcttga ggaccatcat tggtggtgaa
     1501 ggagagaaga agagagattt tgacttcctg tcttctattg agcttctgat cattgaccag
     1561 gctgacattt acctgatgca gaactgggaa catgtcttgc atttgatgaa ccacatgaac
     1621 ctgttaccct tggactcaca tggggtgaac ttctctagag tacgcatgtg gagcctcaat
     1681 aactggtcca agtattaccg tcagactctg ctctttggtg ccctgcagga tgcccagatc
     1741 aactctgtgt tcaacaagca ctgtgtcaat gctcaaggcc aagtggctgt gaggaatgtc
     1801 cccatgacgg gttccatcag tcatgtgttg gtgcagctgc ctcacgtctt ccagagaatg
     1861 gaagcacaag acctagcttc agtgatcgat gccaggtttc actttttcat aaacaagatt
     1921 ctgcctcagt accgggatgc tgtcatgtct cacaccctca tctatgtccc ctcctacttt
     1981 gactttgttc gtctccgaaa ttacttcaag aaagaagaac tgaactttac acacatctgt
     2041 gagtatacac agaggtctgg cgtctccagg gctcgacact tctttctcca aggagagaag
     2101 cagtttctgc tcctcacaga acgcttccat ttctacaaaa ggtacacaat aaaaggcatc
     2161 aggaacctca tattctacga actgccaaca tacgctcact tctacagtga ggtctgtaat
     2221 atgctgagag ccaccagcag aggagaggag gccacatgga cgtgcactgt gctgtattcc
     2281 aagtatgatg cccagaggct ggctgctgtg gttggtgtgg agcgggcagc acagatgctg
     2341 cagtctccaa agagtgtcca cctcttcatc actggagaaa aatgagtgtg gagtgggaca
     2401 actacattga tggacctcat agacttggtc tgctcactgc ccaggagcag gctctaggca
     2461 gtctgcagtc ctgtgccctg gaaagtgcag tgtgacccgt gcgggtaacc atagctctcg
     2521 gggcccagag cagtaaaagg actgccacac acagaaacca aagcttgtgc ttgtcacact
     2581 ttttaagctg taacttctca attatgattt taatttttta atttaattat tattttatat
     2641 gcaaaaaaaa aaaaaaaaaa aaaaaaaa
//
