LOCUS       NM_001126266             992 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus UTP23, small subunit processome component
            (Utp23), mRNA.
ACCESSION   NM_001126266 XM_001063726 XM_216918
VERSION     NM_001126266.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 992)
  AUTHORS   Timofeeva MN, Kinnersley B, Farrington SM, Whiffin N, Palles C,
            Svinti V, Lloyd A, Gorman M, Ooi LY, Hosking F, Barclay E, Zgaga L,
            Dobbins S, Martin L, Theodoratou E, Broderick P, Tenesa A, Smillie
            C, Grimes G, Hayward C, Campbell A, Porteous D, Deary IJ, Harris
            SE, Northwood EL, Barrett JH, Smith G, Wolf R, Forman D, Morreau H,
            Ruano D, Tops C, Wijnen J, Schrumpf M, Boot A, Vasen HF, Hes FJ,
            van Wezel T, Franke A, Lieb W, Schafmayer C, Hampe J, Buch S,
            Propping P, Hemminki K, Forsti A, Westers H, Hofstra R, Pinheiro M,
            Pinto C, Teixeira M, Ruiz-Ponte C, Fernandez-Rozadilla C, Carracedo
            A, Castells A, Castellvi-Bel S, Campbell H, Bishop DT, Tomlinson
            IP, Dunlop MG and Houlston RS.
  TITLE     Recurrent Coding Sequence Variation Explains Only A Small Fraction
            of the Genetic Architecture of Colorectal Cancer
  JOURNAL   Sci Rep 5, 16286 (2015)
   PUBMED   26553438
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 992)
  AUTHORS   Sloan,K.E., Bohnsack,M.T., Schneider,C. and Watkins,N.J.
  TITLE     The roles of SSU processome components and surveillance factors in
            the initial processing of human ribosomal RNA
  JOURNAL   RNA 20 (4), 540-550 (2014)
   PUBMED   24550520
REFERENCE   3  (bases 1 to 992)
  AUTHORS   Wang M, Anikin L and Pestov DG.
  TITLE     Two orthogonal cleavages separate subunit RNAs in mouse ribosome
            biogenesis
  JOURNAL   Nucleic Acids Res 42 (17), 11180-11191 (2014)
   PUBMED   25190460
REFERENCE   4  (bases 1 to 992)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 992)
  AUTHORS   Takagi M, Absalon MJ, McLure KG and Kastan MB.
  TITLE     Regulation of p53 translation and induction after DNA damage by
            ribosomal protein L26 and nucleolin
  JOURNAL   Cell 123 (1), 49-63 (2005)
   PUBMED   16213212
  REMARK    Erratum:[Cell. 2005 Nov 4;123(3):536-7]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473950.2.
            
            On or before May 7, 2008 this sequence version replaced
            XM_216918.4, XM_001063726.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161887.1, CK604137.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..992
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q31"
     gene            1..992
                     /gene="Utp23"
                     /gene_synonym="RGD1307179"
                     /note="UTP23, small subunit processome component"
                     /db_xref="GeneID:299900"
                     /db_xref="RGD:1307179"
     exon            1..266
                     /gene="Utp23"
                     /gene_synonym="RGD1307179"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..828
                     /gene="Utp23"
                     /gene_synonym="RGD1307179"
                     /note="UTP23, small subunit (SSU) processome component,
                     homolog"
                     /codon_start=1
                     /product="rRNA-processing protein UTP23 homolog"
                     /protein_id="NP_001119738.1"
                     /db_xref="GeneID:299900"
                     /db_xref="RGD:1307179"
                     /translation="MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQ
                     LRDQLPRYLMGETQLCTTRCVLKELETLGKELYGAKLIAQKCQVRNCPHFKSAVSGSE
                     CLLSMVDDGNPHHYFVATQDQNLSVKVKKNPGIPLMFIIQNTIVLDKPSPRTVAFVKA
                     VEAGQLVSVHEKQSIKELKEEQGLVRNPELRKRRKKKKVGGPNPLSCLKKKKKAQDTK
                     SPASEKKRKRKRIRIRNKSTPKVSAQQGAEG"
     exon            267..441
                     /gene="Utp23"
                     /gene_synonym="RGD1307179"
                     /inference="alignment:Splign:2.1.0"
     exon            442..992
                     /gene="Utp23"
                     /gene_synonym="RGD1307179"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaggcgttt cgttccgggg agtagacttg gagtgcggaa gtgaaggtcg cgcctgttgt
       61 cctgttgctt aagcaggcat gaagatcacc aggcagaaac acgccaagaa gcatcttggc
      121 tttttccgca acaatttcgg agtccgcgag ccctaccaga tccttctaga tggcacattc
      181 tgccaggcgg cgctgcgggg tcgcatccag ctgcgggacc agctgccccg ctaccttatg
      241 ggagagaccc agctgtgcac cacgagatgt gtgttaaagg agttagaaac actgggaaag
      301 gaattatatg gagccaaact gattgcacag aaatgccagg ttcgaaactg tcctcatttc
      361 aagagcgcag tgagtggatc tgaatgtctc ctgtctatgg tggatgacgg gaatcctcac
      421 cattatttcg tggccacaca ggatcagaac ttatctgtga aagtcaagaa aaatcctgga
      481 attcctctca tgttcattat tcagaacacc atagtgttgg acaagccttc tcccagaacc
      541 gtggcctttg tgaaggcggt ggaggcaggc cagctggtct ctgtgcacga gaaacaaagc
      601 atcaaggaac tcaaggagga gcaaggcttg gtgcggaacc ctgaactgag gaagaggaga
      661 aaaaaaaaga aggtgggcgg ccccaatcct ctcagctgcc tgaagaaaaa gaagaaagca
      721 caggatacaa agtcccctgc ttcggaaaag aaaaggaaaa ggaaacggat tcggattcga
      781 aacaaatcca ctcctaaagt gtctgcgcag cagggtgcgg aaggatgatg ggtgctgtgg
      841 ctactcagat gtcagagtga aagcgaattt ccttctcaaa ctgtgaaaat gtttatacca
      901 gaggactaac ttatttttgt aaactaatac tggcacatac acttttgcct aaaattaaag
      961 aatggttggg tttgtcagtg tgcatcttca gt
//
