LOCUS       NM_001135039            2500 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus UTP18 small subunit processome component (Utp18),
            mRNA.
ACCESSION   NM_001135039 XM_001081275 XM_220851
VERSION     NM_001135039.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2500)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 2500)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 2500)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   4  (bases 1 to 2500)
  AUTHORS   Yokoyama,A., Wang,Z., Wysocka,J., Sanyal,M., Aufiero,D.J.,
            Kitabayashi,I., Herr,W. and Cleary,M.L.
  TITLE     Leukemia proto-oncoprotein MLL forms a SET1-like histone
            methyltransferase complex with menin to regulate Hox gene
            expression
  JOURNAL   Mol Cell Biol 24 (13), 5639-5649 (2004)
   PUBMED   15199122
REFERENCE   5  (bases 1 to 2500)
  AUTHORS   Lee,N.H., Weinstock,K.G., Kirkness,E.F., Earle-Hughes,J.A.,
            Fuldner,R.A., Marmaros,S., Glodek,A., Gocayne,J.D., Adams,M.D.,
            Kerlavage,A.R. et al.
  TITLE     Comparative expressed-sequence-tag analysis of differential gene
            expression profiles in PC-12 cells before and after nerve growth
            factor treatment
  JOURNAL   Proc Natl Acad Sci U S A 92 (18), 8303-8307 (1995)
   PUBMED   7667285
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001135039.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1045022.1,
                                           SRR26360186.2922693.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-350               JAXUCZ010000010.1  79335408-79335757   c
            351-460             JAXUCZ010000010.1  79333834-79333943   c
            461-559             JAXUCZ010000010.1  79332238-79332336   c
            560-630             JAXUCZ010000010.1  79330321-79330391   c
            631-719             JAXUCZ010000010.1  79328492-79328580   c
            720-845             JAXUCZ010000010.1  79326031-79326156   c
            846-1020            JAXUCZ010000010.1  79325768-79325942   c
            1021-1121           JAXUCZ010000010.1  79319328-79319428   c
            1122-1212           JAXUCZ010000010.1  79318653-79318743   c
            1213-1336           JAXUCZ010000010.1  79317296-79317419   c
            1337-1511           JAXUCZ010000010.1  79315314-79315488   c
            1512-1654           JAXUCZ010000010.1  79311411-79311553   c
            1655-1697           JAXUCZ010000010.1  79310247-79310289   c
            1698-2500           JAXUCZ010000010.1  79308787-79309589   c
FEATURES             Location/Qualifiers
     source          1..2500
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..2500
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /note="UTP18 small subunit processome component"
                     /db_xref="GeneID:303456"
                     /db_xref="RGD:1309957"
     exon            1..350
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..1679
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /note="WD repeat domain 50; UTP18, small subunit (SSU)
                     processome component, homolog; UTP18 small subunit (SSU)
                     processome component"
                     /codon_start=1
                     /product="U3 small nucleolar RNA-associated protein 18
                     homolog"
                     /protein_id="NP_001128511.1"
                     /db_xref="GeneID:303456"
                     /db_xref="RGD:1309957"
                     /translation="MPPERRSRTKGDRRAGAMPRRKARPGSGSTPGKAARSSQRTLPA
                     GPKAAPSAISAAEEESRLRQRNRLMLENDKPAAERCLEQLVFGDVEDDEDALLRRLRS
                     SRGHLHGSSDDSEVEDEAVDNLSQKKPVWVDEDDEDEEIVDMMNNRFRKDMMKNASES
                     KLSKDKLQKRLKEEFQHAMGGVPDWAEPGSKRKTSSDDESEEDEDDLLQRTGNFISTS
                     TSLPRGILKMKNCRPANAERPTTARISSVQFHPGAQVVMVSGVDHAISLFQVDGKTNP
                     KIQSIYLEKFPIFKACFSANGEEVLATSMHSKVIYVYDMIAGKLIPVHQVRGLKEKIV
                     KRFEVSPDGSFLLISGIAGFSHLLSMKTKELIGSMKINGRISASTFSSDSKRIYTSSG
                     NGEVYVWDVNSRKCINRFLDEGSLYGLSIAASKNGQYVACGSKSGVVNIYNQDSCLQQ
                     TNPKPIKAIMNLVTGVTSLAFNPTTEILAVASRKMKEAVRLVHLPSCTVFSNFPVYKK
                     STLSRVQTMDFSPRGGYFALGNEQGKALLYRLHHYSDF"
     exon            351..460
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
     exon            461..559
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
     exon            560..630
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
     exon            631..719
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
     exon            720..845
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
     exon            846..1020
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1121
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1212
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1336
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1511
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
     exon            1512..1654
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
     exon            1655..1697
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
     exon            1698..2500
                     /gene="Utp18"
                     /gene_synonym="RGD1309957; Wdr50"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctccacgtga acgtctgcgt ttctcctcag acctgaggat gccgcccgaa cgcaggagcc
       61 ggaccaaagg agaccggaga gccggcgcaa tgccgaggag gaaagccaga cccgggagcg
      121 gcagcacgcc cggaaaggcc gcccgttcat cccaacggac actgccggcc gggccgaagg
      181 cggcccctag cgcgatatcc gcggcggagg aggagagccg gcttcggcag cggaaccgcc
      241 tgatgctcga gaacgacaag ccggctgctg agcgctgcct ggagcagctt gtcttcggcg
      301 acgtcgagga tgacgaggac gcgctgctgc ggcgactgcg gagctcgcgg ggtcatctgc
      361 atggaagctc agatgactcg gaggtggagg acgaagcagt agataatctt tctcagaaga
      421 agccagtttg ggtggatgaa gacgatgaag atgaggaaat agttgacatg atgaacaatc
      481 ggtttcggaa agatatgatg aaaaatgcca gcgaaagtaa actttcaaaa gataaacttc
      541 aaaagagact taaagaagaa ttccagcatg ccatgggagg agtaccagac tgggcagagc
      601 ctggaagcaa gcggaagaca tcttcagatg atgaaagtga agaggatgaa gatgatttgt
      661 tgcaaaggac tgggaatttc atatccacat ccacttctct tccaagagga atcttgaaga
      721 tgaagaactg caggcctgcc aatgctgaac gtcctaccac tgctcggatc tcatcagtac
      781 agttccatcc tggtgcgcag gtggtgatgg tctctggggt agatcatgct atctcactgt
      841 ttcaggttga tggcaaaaca aaccctaaaa tccagagcat ctatttggaa aagtttccaa
      901 tctttaaggc ttgtttcagt gctaatggag aagaggtttt agccacaagt atgcacagca
      961 aggttattta tgtctatgat atgatagctg ggaagttaat tcctgtacat caagtgagag
     1021 gtttgaaaga gaaaatagtg aaacgatttg aagtctcccc agatggctcc ttcttgctca
     1081 taagtggcat tgctgggttt tctcatttgc tatcaatgaa gaccaaagag ctgataggta
     1141 gcatgaagat taatggaaga atttcagcat ccacattctc ctcagatagt aagaggatat
     1201 atacctcttc tgggaatgga gaagtttatg tgtgggatgt gaattcaagg aagtgcatta
     1261 accgatttct tgatgaaggc agtttatatg gattaagcat tgccgcgtca aagaatggac
     1321 agtatgtggc ttgtggttct aagagtggag tggtaaacat atacaatcaa gattcctgcc
     1381 tccaacaaac aaacccaaag ccaataaaag caataatgaa cctggttacg ggtgtcactt
     1441 ccttggcctt caaccctacc acagaaatct tggcagtggc atcaagaaaa atgaaagaag
     1501 ctgtcagatt ggttcatctt ccttcctgta cagtattttc taactttcca gtttataaga
     1561 agagtactct ttctcgtgtt cagaccatgg atttttctcc cagaggtgga tactttgcct
     1621 tagggaatga gcaagggaag gccctgctgt ataggttgca tcattactca gacttctgaa
     1681 gatttttttt ttatgaaatt cagtcaaaac atcccatctc tacatcccag acatttccaa
     1741 gtgtgtgtga taatatatgg ataatgactt atggaatctg cttaaattag cagcagtgtc
     1801 ttaataaatg tatgatagct ttgtttgaca ataagtgtac atgattcttt ttaatctata
     1861 cacacagtca agaatgtgat ttggatgcat tttctttaaa actaaatgtg agaaagggaa
     1921 atggaaacct gtctgtaata aaaaataata taggtggata ttttcattaa tgttcctcct
     1981 gtgtacagat ctggccaggc ttcagagcag tcaccatttt tttttttttt tttttctttg
     2041 agatggtttg tctctgtaac tctggctgtc ttggaacttg ctatgcagac caggctgact
     2101 tcacagagat ctgcttcagc ctccaaagtg ctaatactaa ataataaaca tattaaattg
     2161 tatatgccac tccacctggc tctagcacca attctttact caagaatttt tatctatgta
     2221 tataggtata aaaattggta tataagcatt tatttatata attttaccac ctagggtaaa
     2281 aagcaagttt gtatactaaa gagatagatg taaatgttta ttacataaag aattgtttct
     2341 tggctgaatt tgatactgga agacacagtt tttgattttg taatcacaga tgagaatgtt
     2401 gtaccttaat acattataga aaatggaaga agtaatattt aggactgttt cagaaattag
     2461 aaattctgtt ctaatcctta ttaaacttta attactaaaa
//
