LOCUS       NM_001107978            1343 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus UTP11, small subunit processome component
            (Utp11), mRNA.
ACCESSION   NM_001107978 XM_001056249 XM_233498
VERSION     NM_001107978.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1343)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 1343)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 1343)
  AUTHORS   Heese,K., Nagai,Y. and Sawada,T.
  TITLE     Comparative gene identification-94--a pivotal regulator of
            apoptosis
  JOURNAL   Neuroscience 116 (2), 321-324 (2003)
   PUBMED   12559088
  REMARK    GeneRIF: CGI-94 interacts with second mitochondria-derived
            activator of caspases/Diablo, inhibits nerve growth factor-induced
            neurite outgrowth and that its neuronal expression leads to cell
            death point to its pivotal role in the control of cellular
            survival.
REFERENCE   4  (bases 1 to 1343)
  AUTHORS   Heese,K., Nakayama,T., Hata,R., Masumura,M., Akatsu,H., Li,F.,
            Nagai,Y., Yamamoto,T., Kosaka,K., Suemoto,T. and Sawada,T.
  TITLE     Characterizing CGI-94 (comparative gene identification-94) which is
            down-regulated in the hippocampus of early stage Alzheimer's
            disease brain
  JOURNAL   Eur J Neurosci 15 (1), 79-86 (2002)
   PUBMED   11860508
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC168964.1.
            
            On Sep 4, 2008 this sequence version replaced NM_001107978.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168964.1, FQ226285.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1343
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1343
                     /gene="Utp11"
                     /gene_synonym="Cgi-94; Cgi94; RGD1559610; Utp11l"
                     /note="UTP11, small subunit processome component"
                     /db_xref="GeneID:313581"
                     /db_xref="RGD:621412"
     exon            1..131
                     /gene="Utp11"
                     /gene_synonym="Cgi-94; Cgi94; RGD1559610; Utp11l"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..830
                     /gene="Utp11"
                     /gene_synonym="Cgi-94; Cgi94; RGD1559610; Utp11l"
                     /note="U3 snoRNA-associated protein 11; UTP11-like, U3
                     small nucleolar ribonucleoprotein; UTP11, small subunit
                     processome component homolog"
                     /codon_start=1
                     /product="probable U3 small nucleolar RNA-associated
                     protein 11"
                     /protein_id="NP_001101448.1"
                     /db_xref="GeneID:313581"
                     /db_xref="RGD:621412"
                     /translation="MSAAFRKAAKTRQREHRERSQPGFRKRLGLLEKKKDYKLRANDY
                     HKKQDFLRALRKKALEKNPDEFYYKMTRAKLQDGVHIFKDNKEEVTAEQLKLMRTQDI
                     KYIEMKRVAEAKKIERLKSELHLLDVQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPE
                     LLDRVYNRPRIETLQKERVKGVTPQTRLKRIAKERQKQYDCLTQRIEREKQLFVVAQK
                     IQTRKDLMDKTQKVKVKKETVNSPAIYRFQTRRKR"
     exon            132..193
                     /gene="Utp11"
                     /gene_synonym="Cgi-94; Cgi94; RGD1559610; Utp11l"
                     /inference="alignment:Splign:2.1.0"
     exon            194..296
                     /gene="Utp11"
                     /gene_synonym="Cgi-94; Cgi94; RGD1559610; Utp11l"
                     /inference="alignment:Splign:2.1.0"
     exon            297..410
                     /gene="Utp11"
                     /gene_synonym="Cgi-94; Cgi94; RGD1559610; Utp11l"
                     /inference="alignment:Splign:2.1.0"
     exon            411..504
                     /gene="Utp11"
                     /gene_synonym="Cgi-94; Cgi94; RGD1559610; Utp11l"
                     /inference="alignment:Splign:2.1.0"
     exon            505..635
                     /gene="Utp11"
                     /gene_synonym="Cgi-94; Cgi94; RGD1559610; Utp11l"
                     /inference="alignment:Splign:2.1.0"
     exon            636..746
                     /gene="Utp11"
                     /gene_synonym="Cgi-94; Cgi94; RGD1559610; Utp11l"
                     /inference="alignment:Splign:2.1.0"
     exon            747..1319
                     /gene="Utp11"
                     /gene_synonym="Cgi-94; Cgi94; RGD1559610; Utp11l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcggctggt tcttgtagtg cggtcgccgt ggtggagttt gccgagcatt tcttagacct
       61 caggaggcat gtcggcggct tttcgcaagg cagccaagac ccggcagcgg gaacaccgag
      121 aacgaagcca gcctggcttt cggaaacgcc tgggtttgct agagaaaaag aaagattaca
      181 aactccgtgc aaatgactat cataaaaaac aagatttcct cagagctctc cggaagaagg
      241 ctcttgaaaa aaatccagat gaattctact ataaaatgac tcgggccaag ctccaggacg
      301 gagttcatat tttcaaagac aacaaggaag aagtgacagc agagcagcta aaactgatga
      361 gaactcagga catcaagtac atagagatga agagggtggc ggaggcgaag aaaattgaaa
      421 gactgaaatc agagctccac ctgctggatg tccaggggaa gcaacagaat aagcacgtgt
      481 tcttttttga caccaaaaag gaagttgaac agtttgatgt tgcgactcac ttgcagacgg
      541 ccccagaact actcgatagg gtctataata gacccagaat agagaccttg cagaaggaga
      601 gagtgaaagg agttacccct cagactcgcc tcaagcggat agccaaagaa cgacaaaagc
      661 agtatgactg cttgacacag cgcatcgagc gggagaagca gctgtttgtt gttgcccaga
      721 aaatccagac acgcaaagac ctcatggata aaactcagaa ggtgaaggtg aagaaagaaa
      781 cagtaaactc cccagcgata tacagattcc agactcgccg gaaacgttga tgtcttaaaa
      841 atcagcctca gcagtctgta tggaaaagaa ttcttaccgt tttcctcctt tcttttgtaa
      901 taacttcaga ttttattagt ccaaagggct cggtcttcct cttttgtaat catggcttac
      961 tgtcaaccca gtacttgaca tctttctatg aaaatagtaa agtccctccc cagtgttatt
     1021 gtctctgtat tgatgaactg agcctcttac ataagtactt atgtttgtct aggagagtta
     1081 tataatctca tgtaacaaag tagaaaatag atgaatacat tccattctca gtattaagac
     1141 aacttatcta ttccatagca ggacctaggg ctactgatgt gagcggctac tgcaggcatt
     1201 ctggtttatg ttccccgttt gggagagtta tacattggct ttgtttataa ttttgttttg
     1261 tcattctcct tctagtagat tttattctaa tttttaatta aatcattagt tctattccaa
     1321 aaaaaaaaaa aaaaaaaaaa aaa
//
