LOCUS       NM_001131032            1030 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus undifferentiated embryonic cell transcription
            factor 1 (Utf1), mRNA.
ACCESSION   NM_001131032 XM_001058894
VERSION     NM_001131032.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1030)
  AUTHORS   van Bragt,M.P., Roepers-Gajadien,H.L., Korver,C.M., Bogerd,J.,
            Okuda,A., Eggen,B.J., de Rooij,D.G. and van Pelt,A.M.
  TITLE     Expression of the pluripotency marker UTF1 is restricted to a
            subpopulation of early A spermatogonia in rat testis
  JOURNAL   Reproduction 136 (1), 33-40 (2008)
   PUBMED   18390688
REFERENCE   2  (bases 1 to 1030)
  AUTHORS   Gao,X., Tate,P., Hu,P., Tjian,R., Skarnes,W.C. and Wang,Z.
  TITLE     ES cell pluripotency and germ-layer formation require the SWI/SNF
            chromatin remodeling component BAF250a
  JOURNAL   Proc Natl Acad Sci U S A 105 (18), 6656-6661 (2008)
   PUBMED   18448678
REFERENCE   3  (bases 1 to 1030)
  AUTHORS   Kristensen,D.M., Nielsen,J.E., Skakkebaek,N.E., Graem,N.,
            Jacobsen,G.K., Rajpert-De Meyts,E. and Leffers,H.
  TITLE     Presumed pluripotency markers UTF-1 and REX-1 are expressed in
            human adult testes and germ cell neoplasms
  JOURNAL   Hum Reprod 23 (4), 775-782 (2008)
   PUBMED   18281244
REFERENCE   4  (bases 1 to 1030)
  AUTHORS   Wissmuller,S., Kosian,T., Wolf,M., Finzsch,M. and Wegner,M.
  TITLE     The high-mobility-group domain of Sox proteins interacts with
            DNA-binding domains of many transcription factors
  JOURNAL   Nucleic Acids Res 34 (6), 1735-1744 (2006)
   PUBMED   16582099
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1030)
  AUTHORS   Fukushima,A., Okuda,A., Nishimoto,M., Seki,N., Hori,T.A. and
            Muramatsu,M.
  TITLE     Characterization of functional domains of an embryonic stem cell
            coactivator UTF1 which are conserved and essential for potentiation
            of ATF-2 activity
  JOURNAL   J Biol Chem 273 (40), 25840-25849 (1998)
   PUBMED   9748258
REFERENCE   6  (bases 1 to 1030)
  AUTHORS   Okuda,A., Fukushima,A., Nishimoto,M., Orimo,A., Yamagishi,T.,
            Nabeshima,Y., Kuro-o,M., Nabeshima,Yi., Boon,K., Keaveney,M.,
            Stunnenberg,H.G. and Muramatsu,M.
  TITLE     UTF1, a novel transcriptional coactivator expressed in pluripotent
            embryonic stem cells and extra-embryonic cells
  JOURNAL   EMBO J 17 (7), 2019-2032 (1998)
   PUBMED   9524124
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001131032.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EU176857.1, EV772699.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMN17050749
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-557               JAXUCZ010000001.1  204169954-204170510
            558-1030            JAXUCZ010000001.1  204170608-204171080
FEATURES             Location/Qualifiers
     source          1..1030
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..1030
                     /gene="Utf1"
                     /note="undifferentiated embryonic cell transcription
                     factor 1"
                     /db_xref="GeneID:681901"
                     /db_xref="RGD:1589375"
     exon            1..557
                     /gene="Utf1"
                     /inference="alignment:Splign:2.1.0"
     CDS             2..1018
                     /gene="Utf1"
                     /codon_start=1
                     /product="undifferentiated embryonic cell transcription
                     factor 1"
                     /protein_id="NP_001124504.2"
                     /db_xref="GeneID:681901"
                     /db_xref="RGD:1589375"
                     /translation="MLLRPRRLPAFAPPSPGSPDAELRAAGDVPVTTSDAFATSGAMA
                     DPGSPKAPVSPGSAQRTPWSARETELLLGTLLQPAVWRSLLLDRRQALPTYRRVSAAL
                     ARQQVRRTPAQCRRRYKFLKDKLRDSQGQPSGPFDDQIRQLMGLLGDDGPPRVRRRSA
                     GPGRPQRRGRSAFSALAPAPAVVEQEAELPLAAENAEPAPALRFSSSTTKSAGVRRIT
                     SSPPPTAIDTLPPEPGHTLESSPTPTPDHDTENPNEPPGLSQGRASPQVAPQSLNTAL
                     LQTLTHLGDISTVLGPLRDQLSTLNQHVEHLRGSFDQTVSLAVGFILGSAASERGILG
                     DLRQ"
     exon            558..1030
                     /gene="Utf1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gatgctgctc cgtccccgga ggttgcccgc ttttgctccg ccgtcgccag gtagccccga
       61 cgccgagcta cgggcggccg gggacgtccc ggtgactacg tctgatgcct tcgctacttc
      121 gggcgcgatg gcggatcctg gctcgcccaa ggctcccgtg tccccgggct cggcgcagcg
      181 cacgccctgg agtgcccgag agacggagct acttctgggc acgctgctgc agccggcggt
      241 gtggcgctca ctcctgctgg accgccggca ggctctaccc acttaccgcc gcgtgtccgc
      301 cgcactggcc cgtcagcaag ttcggcgcac gcccgctcag tgccgccgtc gctacaagtt
      361 cctcaaggac aaactccgag actcccaggg ccagccgtcc ggacccttcg atgaccagat
      421 ccgccagctc atggggctat tgggtgacga tgggccgccg cgggtccgcc gccgttctgc
      481 tggtcctgga cgtccccagc gccgtggtcg ctcagccttc tccgcgttag cacccgcacc
      541 tgcagtggtg gagcaagagg ccgagctgcc gctggctgcg gaaaacgccg aacctgcccc
      601 cgcgctcaga ttcagctctt ccactacgaa gtctgcaggc gtccgccgca ttaccagctc
      661 cccacctcct acggccatcg ataccttgcc tcctgagccg ggccataccc tcgaatcctc
      721 cccgacgcca acccccgacc acgacacgga gaacccgaat gagcctcctg gcctttccca
      781 gggccgtgct tcccctcagg ttgctcccca gtctctgaat accgcattgc tgcagacctt
      841 gacgcacttg ggcgacatct caacagttct gggccctctg cgcgaccagc tgtcgaccct
      901 gaaccagcac gtggagcatc tacgaggttc cttcgaccaa accgtttctc tggctgtggg
      961 gttcattctg ggcagtgcag cctccgagcg gggcatcctt ggggacttgc gacaataaag
     1021 aagctttgtt
//
