LOCUS       NM_001108252            2310 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus ubiquitin specific peptidase 51 (Usp51), mRNA.
ACCESSION   NM_001108252 XM_001066361 XM_228809
VERSION     NM_001108252.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2310)
  AUTHORS   Wang Z, Zhang H, Liu J, Cheruiyot A, Lee JH, Ordog T, Lou Z, You Z
            and Zhang Z.
  TITLE     USP51 deubiquitylates H2AK13,15ub and regulates DNA damage response
  JOURNAL   Genes Dev 30 (8), 946-959 (2016)
   PUBMED   27083998
REFERENCE   2  (bases 1 to 2310)
  AUTHORS   Quesada V, Diaz-Perales A, Gutierrez-Fernandez A, Garabaya C, Cal S
            and Lopez-Otin C.
  TITLE     Cloning and enzymatic analysis of 22 novel human ubiquitin-specific
            proteases
  JOURNAL   Biochem Biophys Res Commun 314 (1), 54-62 (2004)
   PUBMED   14715245
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474063.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_228809.4, XM_001066361.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB790453.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132263, SAMD00132265
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2310
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq12"
     gene            1..2310
                     /gene="Usp51"
                     /gene_synonym="RGD1562211"
                     /note="ubiquitin specific peptidase 51"
                     /db_xref="GeneID:317398"
                     /db_xref="RGD:1562211"
     exon            1..76
                     /gene="Usp51"
                     /gene_synonym="RGD1562211"
                     /inference="alignment:Splign:2.1.0"
     exon            77..2310
                     /gene="Usp51"
                     /gene_synonym="RGD1562211"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..2183
                     /gene="Usp51"
                     /gene_synonym="RGD1562211"
                     /EC_number="3.4.19.12"
                     /note="ubiquitin specific protease 51"
                     /codon_start=1
                     /product="ubiquitin carboxyl-terminal hydrolase 51"
                     /protein_id="NP_001101722.1"
                     /db_xref="GeneID:317398"
                     /db_xref="RGD:1562211"
                     /translation="MAHVREASRSSRSVACWSSGGGRGACLEQAAENASRMEQTMRGT
                     QGAQEMKPELWPEPKPTSENLTSRGSGSDEKVLPSIPAACHTSSSSVCPRRKPRPRPQ
                     PRSRSRGGRGLKAPPPPPAKPPPPPPAPPPPPLPKPRPVAWRNSRRRPRPAPRPQTRK
                     SYPSDPGCSGDSDGTENRLLEVGFDKGPTGCSHVEIFKVAKNWRRNLRMIYQRFIWSG
                     TPETRKRKAKTCICRVCSTHKNRLHSCLSCVFFGCFTEKHIHIHAETKQHNLAVDLYH
                     GVIYCFMCKDYVYDKDIEKIAKETKEKILGLLMSTAGDMSYQQLMASEVEENQSICES
                     KEQETSLVKPKKKRRKKTVYYTVGLRGLINLGNTCFMNCIVQALTRIPLLKEFFLSDK
                     HKCMMTSPSLCLVCEMSSLFQAMYSGNQSPHIPYKLLHLIWIHAEHLAGYRQQDAHEF
                     LIAILDVLHRHSRDDGIEQEGNLNHCNCIIDYIFTGGLQSDVTCQVCHGVSTTIDPCW
                     DISLDLPVSYTPGRAGSTGQKPRVISLTDCLKWFTRPEDLGSSAKIKCSRCQSYQQST
                     KQLTMKKLPIVACFHLKRFEHLGKQRRKINTFISFPLELDMTPFLASTKESIMKGQPL
                     TECVPIENKYSLFAVINHHGTLESGHYTSFVRQEKDQWFSCDDAVVTKATMEELLYSE
                     GYLLFYHRQDIEKE"
ORIGIN      
        1 agagaagact ggcagaggag cgcctggaca gcagcagcag ctgactttct agatcaagcg
       61 cgccttgggg ccccaggctt gggagtgagc cgatggccca cgttcgagaa gcgtcccggt
      121 cctcccgctc cgtcgcctgt tggagttcgg gaggtggtcg aggagcctgt ttggagcagg
      181 cggctgagaa tgcatcgaga atggagcaga cgatgcgggg tacacaggga gcccaggaga
      241 tgaagccgga gctgtggccg gagcccaagc ccacgtcgga gaacttaaca agtaggggca
      301 gtggcagcga tgagaaggtg ctcccttcta tcccggctgc ttgtcacacc agctccagct
      361 cggtttgccc gcgccgcaag ccccgccctc ggccccagcc caggtcccgc tccaggggag
      421 ggcgtgggct caaggcccca cccccgcctc ccgccaaacc tccgcctccc ccgccagcgc
      481 cgccgccacc acccctgccc aagccgcggc cggtggcctg gcgcaattcc aggcgtagac
      541 ccaggcctgc acccagaccc caaacacgga aaagctaccc tagtgaccca ggctgctctg
      601 gggactcaga tggcacagag aacaggttac tggaggtagg gtttgataag ggtcccacag
      661 gctgctctca tgtagagatc tttaaagtag ctaaaaactg gcggaggaac ctgcggatga
      721 tctatcagcg tttcatttgg agtggaaccc cggagactag gaagcgtaag gcaaagacat
      781 gcatctgtcg tgtatgtagt acgcataaga acagactcca ctcttgtctg tcctgtgtat
      841 ttttcggatg ctttactgag aaacatattc atattcatgc agaaactaag caacacaatt
      901 tagcagtaga cctctaccat ggggttatat attgctttat gtgtaaggat tatgtatatg
      961 acaaagatat agaaaagatt gccaaagaaa caaaagagaa aattctggga ctcttaatgt
     1021 ccactgcagg agatatgtct tatcagcaac taatggcatc tgaggttgaa gaaaatcaat
     1081 caatctgtga gtccaaagaa caggagacca gtttggtaaa acccaagaaa aagaggagga
     1141 agaagacagt gtattatact gtaggcctca gagggttaat taatcttggg aatacttgct
     1201 ttatgaactg tattgtccag gcacttaccc gcattccact actgaaggag ttcttccttt
     1261 cggataagca caaatgcatg atgacaagcc ccagcttgtg tttggtctgt gagatgtctt
     1321 cactttttca agctatgtac tcggggaacc aaagtcctca tattccctat aaattgcttc
     1381 acctgatatg gatccatgca gagcatctag ctgggtacag gcaacaggat gctcatgagt
     1441 ttctgattgc aatattagat gtgttgcata gacacagcag agatgatggc atcgagcaag
     1501 aaggtaacct caaccactgt aactgcatca tagactacat ctttacaggt ggcctgcagt
     1561 ccgatgtcac ctgtcaagtc tgtcatggtg tctccaccac tatagaccca tgctgggaca
     1621 ttagtctgga cttgcctgtc tcttataccc cagggagggc tggcagcaca ggccagaagc
     1681 cacgagtcat ctcacttaca gattgcctga agtggtttac aaggcccgaa gacctgggaa
     1741 gcagtgccaa aatcaaatgc agtcgatgcc aaagctacca gcaatctacc aaacagctca
     1801 caatgaagaa attaccgatt gtggcctgct ttcatctgaa acggtttgaa catttaggca
     1861 aacagagacg caagattaat acttttatct catttccttt ggagctagac atgacaccct
     1921 ttttggcctc tactaaagaa agcataatga aaggccagcc attaacggag tgtgtgccaa
     1981 ttgagaataa atattctttg tttgcagtga ttaaccacca tggtactttg gaaagtggcc
     2041 attacaccag ctttgtccgt caggaaaagg accagtggtt cagctgcgat gatgctgtag
     2101 tcactaaggc tacaatggag gagttactct atagtgaagg gtatctactg ttctatcaca
     2161 ggcaagatat agagaaagaa taatcttacc cagaatgata caatttccag accaaaattt
     2221 taaaaagtta aacaaaaaaa gaaaaacaaa aaaacaaaaa aaaaaaacaa aaaaaaaaaa
     2281 caaaaaagaa gaaaaagaag aaaaaataat
//
