LOCUS       XM_006237940            8532 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ubiquitin specific peptidase 45
            (Usp45), transcript variant X3, mRNA.
ACCESSION   XM_006237940
VERSION     XM_006237940.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051340.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006237940.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006237940.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8532
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..8532
                     /gene="Usp45"
                     /note="ubiquitin specific peptidase 45; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 19 ESTs, 1 Protein, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     140 samples with support for all annotated introns"
                     /db_xref="GeneID:313098"
                     /db_xref="RGD:1310976"
     CDS             82..2520
                     /gene="Usp45"
                     /codon_start=1
                     /product="ubiquitin carboxyl-terminal hydrolase 45 isoform
                     X2"
                     /protein_id="XP_006238002.1"
                     /db_xref="GeneID:313098"
                     /db_xref="RGD:1310976"
                     /translation="MRVKDPSKDLPEKGKRSKRPLLPHDEDSSDDIAGLTCQHISYAV
                     SVNHVKKAVAETLWSVCSECLKERRLCDGQPVLPSDVWLCLKCGFQGCGKNSESQHSL
                     RHFKSSGAESHCVVISLSTWVIWCYECNEKLSTHCNKKVLAQIVDFLQKHVFKTQTDA
                     FSRIIKLCEEKREAGEIKKGKKGCAVPSVKGITNLGNTCFFNAVIQNLAQTYILFELM
                     NEIKEDGTKFKISLSSAPQLEPLVVELSSPGPLTSALFLFLHSMKEAEKGPLSPKVLF
                     NQLCQKAPRFKGFQQQDSQELLHHLLDAVRTEETKRIQASILKAFNNPTTKTADEETR
                     KKVKAYGKEGVKMNFIDRIFIGELTSTVMCEECANISTMKDPFIDISLPIIEERVSKP
                     VLLGKMSKCRSLQETDQDHNKGTVTVENTHPPRAAKKHSSPKDKTLLSHDRKHLRKWP
                     SEEERTVGTHPNSENSEASPLAGILSNEASLNESPTEGSERDTSLESSVDADSEASEP
                     EVAYKPSVLLRSSGDPGAHGEQHPHLPLASELPHTKETHDCDEEMAEAMAELHLSGTV
                     TGNRDFHREKQPLNVPNNVCFSEGKHTKLHSAQNAFQTLSQSYVTTSKECSVQSCLYQ
                     FTSMELLMGNNKLLCEDCTEKKRKCQKETSSAERKAGGVYTNARKQLLISAVPAILIL
                     HLKRFHQAGLSLRKVNRHVDFPLTLDLAPFCAATCKNISVGEKVLYGLYGIVEHSGSM
                     RGGHYTAYVKVRVPSRKLSECITGRKTAPGLKEADSELGGHWVHVSDTYVQVVPESRA
                     LSAQAYLLFYERIL"
ORIGIN      
        1 cgccttctcc ggttcccctc tgcacaggcg cagaagctcc tgcgtgtgga agctgcggcc
       61 cggcgggcgg ggaaataaca gatgcgggta aaagatccat ccaaagatct acctgagaaa
      121 ggcaaaagaa gtaaaagacc actgctacct cacgatgaag attcttcaga tgacattgct
      181 ggtttaacat gccagcacat cagttatgct gtcagtgtga accatgtgaa gaaggcagta
      241 gctgagactc tctggtcagt ttgttcagag tgtttgaaag agagaagact ctgtgatgga
      301 cagccggtac ttccttccga tgtttggttg tgcctcaagt gcggttttca gggatgcggt
      361 aagaactcag aaagccagca ttcactgaga cacttcaaga gctctggggc ggagtcccat
      421 tgtgttgtca ttagcctgag cacatgggtc atatggtgtt atgaatgtaa tgaaaaatta
      481 tcgacacatt gcaacaagaa agttttggct cagatagttg attttctcca gaaacatgtt
      541 tttaaaacac aaacagatgc attttctaga atcataaaac tttgtgaaga aaaacgtgaa
      601 gcaggggaaa taaagaaggg gaagaaaggc tgtgctgtgc catctgtcaa aggaattaca
      661 aacttaggaa atacttgctt ttttaatgcc gtcatccaga acttggctca gacttacatt
      721 ctttttgaac tgatgaacga gataaaagaa gatggcacca aattcaagat ttctctttcg
      781 tcagctccac agctggagcc gttagtggtg gaactttcaa gccctggacc attgacttca
      841 gccttgttcc tgtttcttca cagcatgaag gaagctgaaa aaggaccact ttctcctaaa
      901 gttcttttca atcagctctg tcagaaggct cctcgattta aaggtttcca gcaacaggac
      961 agccaggagc ttctgcacca tttgttggat gcagtgagga cagaggagac aaagaggata
     1021 caagctagca ttctaaaagc gttcaacaat ccaactacca agactgctga tgaggaaact
     1081 agaaaaaaag tcaaagccta tggaaaggaa ggcgtgaaga tgaacttcat agatcggatc
     1141 ttcattggcg aattaactag cacagtcatg tgtgaagaat gtgctaacat ctctaccatg
     1201 aaggatccct tcatagatat ttcacttcct atcatagaag aaagggtttc aaaacctgta
     1261 cttttgggga aaatgagtaa atgcagaagt ttacaggaaa cagaccaaga tcataacaag
     1321 ggcaccgtta cagtagaaaa tacccatcca ccaagagctg ccaagaagca ttcctcacct
     1381 aaagataaga ctctgctaag tcatgacaga aaacatttaa gaaaatggcc gtctgaagaa
     1441 gagagaactg ttggtacaca tccgaacagt gaaaactcgg aagccagccc tttggccggc
     1501 atcctcagca atgaggcatc gctgaacgaa agccccactg agggcagtga gagagacacc
     1561 agcctagaaa gcagtgtgga tgcggacagc gaggcttctg aacccgaggt ggcttacaag
     1621 ccgtctgtgc tgctccgatc cagtggtgat cccggcgcgc acggggaaca gcacccacac
     1681 ctcccactgg caagtgaatt gccacacacc aaggagacgc acgactgcga tgaggaaatg
     1741 gcggaagcga tggctgagct tcatttgagc ggcactgtaa ctggaaatag agattttcac
     1801 agggaaaaac agccactaaa tgtcccaaat aatgtgtgtt tttcagaggg aaaacatacg
     1861 aagcttcaca gtgcccaaaa tgcttttcag actctttctc agagctatgt aactacttct
     1921 aaagaatgct cagttcagtc ctgtctctac cagttcacat ccatggagtt actaatgggc
     1981 aacaacaagc tgctctgtga ggactgcact gaaaagaaac ggaagtgcca aaaggaaacc
     2041 agttctgcag aaaggaaggc aggaggagtt tatactaatg ccaggaagca actactcata
     2101 tctgctgttc cagctatcct aatccttcat cttaaaaggt tccaccaggc tggcttgagt
     2161 cttcgtaaag taaacagaca tgtagacttc ccgcttaccc ttgacttagc accgttctgt
     2221 gctgctacct gtaagaatat aagtgtgggg gagaaggttc tctatggtct ctacggtata
     2281 gtggagcaca gcggctcaat gagaggaggc cactacactg cttacgtgaa ggtgcgagtg
     2341 ccctccagga agctgtccga gtgcatcacc gggaggaaga ctgcaccagg tttgaaagaa
     2401 gctgatagtg aattgggagg ccactgggtc catgtcagcg acacttatgt gcaagtggtt
     2461 ccagaatcaa gagcactgag tgcgcaagct tatctccttt tttatgaaag aatattataa
     2521 ttatctgtta attgttattt agttcatttt tattttaatg ctgaagtcgt aactgtaata
     2581 tgtaatgtgc ctttgtagtc tgtagaaata gtgcgtcctt ccagtgttac ttaactttgt
     2641 cgatatgcag tgaatccttt aaagaaatta attaatgtga caggcagttg tggtgctcgc
     2701 ctttattcca gcacttggaa ggcagaggca ggcagatctg tgaaaaacct tgtcttgaaa
     2761 aataaaacaa aaaagtaatt aatgctttca aatctatatt cttaagtgta gaaacatgtt
     2821 ttatgttaat tttcatgtcc atggagattg ccactcacca ccaaaaaaaa aaagaaaaga
     2881 aagaaaaagt tgatggtagt ggagagatcc ccttcgcgac gtgactcgtc actacagaca
     2941 ttcagagacg atgctggatc gggtctctag tggatccttc tcgagtggac gcagtgtatc
     3001 ttgtgcttac ttttgtttta gccttttaca atctcggccc tgttttgaat cactcttcac
     3061 atttctctgt gcgtgtcatt tttctagtaa acattggtgt aagtttataa ctatgaaaga
     3121 aaaattgccc atccttgcac caccccactt aaaatcatct cagggctttg cagtggttgg
     3181 tgtgtgtgtt agtcgatggg aaaagtttct agaacagtct gaactagtgc ctaatgtaac
     3241 ataataattt tttcatattt tatgtgactc agtagtatga aaaggaacca ttgtaatttt
     3301 ggtactgtga gtttacaagt aataaattga ttcgcttatc gccttgaata tttgaagata
     3361 ttgagacatt tcataaacta atcatttgca atcctttaaa gacagtttgc aagtgattgg
     3421 ttaaggccaa aataaaaata tagagaattt tgacacatag aactagcata tagaagttgg
     3481 tggtctatat aggaacatag gatactttaa agtttaagga tgtctttgaa ctataaacta
     3541 ccaaactata tttatgagtg gtagaaatca tattcttata attaacaaca aatataatac
     3601 tttttttact tctgtacatt aataaatgtt aaatatggtt ttgtcttcat aagcattatt
     3661 tgaaaagaca ggtggctagt tggggatgta gttcaatggc agagaacttg cttggcctgt
     3721 gtaaggtcct ggttccatcc ccagacacac gaataaaaca ttcaggtcaa tttggctttg
     3781 actttaatgg ggcacagagc tgctacttct gttcccttta aatacgtaga aacacaggag
     3841 agtttctcct tccaaaattc aaagaattga actgtgaaaa cttagcatga aaaatattac
     3901 tacgaagatt ttaaataatc aatgaaatgg ttcagtgata catagtatta aagcaagatg
     3961 taagggaacg ggtccagcgt cttagtcttc agtgcctgtg tttgattcaa tgggcaaatg
     4021 taggggagag aggctgtaag ctgtacagac ctttagccag cgtcgagcct tcttggcatg
     4081 tgtaacataa ggtcacctta tgatgatgcc tcttaatatg cggcggctag gtgaaactga
     4141 tttgtctaat ggagaaattt taaaatacca tggcataact tctattttta agttgcagag
     4201 gaattttcaa tagtatttta aagatttttt tgtattgaag ataaagaact atattttatc
     4261 tgtagagccc agttgtgtcc tctaaaaaga actttccagt gtcttctgtt tcatcagaca
     4321 ttcagagttt attaatctat tgacacgaaa tagtctagca ccagagcaat gagctagaaa
     4381 aatttgctca agtcggcttc tcattcatag cagttgcccc accaaacaaa tgtaaatagt
     4441 taaccttttt ttctctctct cctagaaaag atactattaa gaggtgtaca gtctaggcag
     4501 gttccaatac ctggcatatg acagtatttt atcacccttt aaaacagaaa aacctgccga
     4561 gggtggtggt gcacgcctca gactcagcac tcgggaggca gaggcaggtg catttgagtt
     4621 ccagggcacc caaggctaca cagagaaacc ctgtctcaaa acacttgaag agaaaagaag
     4681 caccctaaaa tctatatatg atttttatac attatcctag tagtgacgtg cagataaaat
     4741 gttcatttat tacctagtgc taaggagatt ctgaaatgca tttttatgac ctaaagtttg
     4801 ttttttcttg ccatctaaaa atggagaaaa atggtttgat tttgatacct aggagtttcc
     4861 tatcaagctt atgttgtaga taaaaatcac acagatgtac acttaaattt ttgttcttat
     4921 tttgaagttt tccaaagcac atttgtagaa attttaaatt gcgaggctac tgtactaaca
     4981 atagtttcca gattacctca ggaaacagtg caaataaaca agaatgttta cagatcaaca
     5041 aaactactcg gtgttttggc acagtgaatt tgaaaggtaa aagagagaag tttttatcca
     5101 gaaactggtt tacagggtaa acccaattct cccctggctc tcccgtattt aaaatgatgt
     5161 gccaattatg tgaatgtttg tgacataaac aaatgtacat ctatatttaa gatttattgt
     5221 ttaatgtttt aaaaaataat atgaagactg cttctgtagg tagtcaagga gatgatcatc
     5281 gtagcagctc agagtcgtat atcaacagag ctattttacc atatctaata atccttagct
     5341 tgcatgtgtg attcattagt gattttatac agtagttgaa taaaattttc tgaagactta
     5401 gctgtgaaat gtcaccgcac atcaaatttt ttagtacaca atagcatcct gcctactttc
     5461 atgaacttta tactcagcat atttttctgc atgacatctg gtccaataaa ccttaaccaa
     5521 gtctgtgcac taaaaccaag ctttcagaga gcatccattg cattattgga gaaattattt
     5581 ctgtactaaa ctggttttgt tcatgtagaa atcatcagtt caactgtgtt taaaagatga
     5641 ttatttttgg gtatcaataa taaattccta gtatcattcc ttctctttta tccaatttta
     5701 cagtatttta aaaatatcta tgtaacttat tgatcattat ttggccattg ctgtatatat
     5761 aaacatccta ataaatatga aattcttatg ttagcagatt aggcctggag ctttgcatta
     5821 tacattattg acaggatatt aataaacatt gtgttcatat ctattttagt cccctggctt
     5881 tctataaaca aaatataatt taagaagctt atgaacaaca aaaatttatt tcctttactt
     5941 ttagcaacca ggaagctcaa gacaaagaca aacagatcca ttttccaaat gaggctctgg
     6001 tgatcctctc tgagcgttca cctggttact agggaaaggg agcagtaggg tcgcctttat
     6061 gagggcttca cgtcagaacc taatcacttt ctaaatactc cagtcacaga actctcacct
     6121 ggggagcttg cgaatgggac acaaacattt agctcacagt gaccttcaag tttcaggaat
     6181 gcgctattta aaaaaaaacc ttgtcaccaa cccgatgctg gagattgtat ctagtagttc
     6241 ttccacccag ctacattctc agtccagaaa ccaaacagac ctgtcagcta tttccctgaa
     6301 aggtttgagt tacttagata ggattgtaca ctaagaaata tgttgtctac atgtctgctt
     6361 ctttaacttt tttagagcca tgaagcttcc agagattttg aggaaagtta gatatttttc
     6421 ttttagagtg tataaagatg ggtttattgc tcttgggcag gttctgatcc caagagtgag
     6481 gccagggaag ttgccatagg gagggagaca gaagggaggt agatgagaaa gagaaagagt
     6541 gtgtgcattc agggaaagga aaagcacaga aggagagggg tagggggaga gggagaaagt
     6601 tacatactta acatttttat ttgatcattt aacaagtgtt tgttgaatac ctgctctttg
     6661 cttggcatta gggatatagc agtgaatgca agaaatcact caagaagaag actgtcaagt
     6721 gagtgtactg gtcttcgttt cagtttcttt tgctgtgatg aaacatcata accacaagca
     6781 actaggagag gagaaggttt atttcattta catttgcata tcacagaggg agtgggggca
     6841 ggatgtgatg cagaggctgg ggagtgctgc ttactggctt actctccatg ttgtctccag
     6901 ttggctttct aaagaaccaa agtccaggcc aggggtagca tcactcacaa tgctctggaa
     6961 ccttccacat caatcactta tttgacagtg cccaaaagac ttgcctagag ccccatctaa
     7021 tagaggcatt ttctcaattg aggctccttt ctctcctctg aatctagctg tgtcaagttg
     7081 acataaaact agctggcaca taaggggaaa aaaaacccaa ataatactgc ttacgtgctg
     7141 ttgggagtaa cacctagcaa agaaggatgt tccagtgagg cacagaactt atgggatatc
     7201 tatatagtaa gtattaaggg aatttattgt aaggacttat agtcttcagt ccaactaacc
     7261 caacagtggg cagccatgaa taggaactcc aggaatctag tagttgctca gtcccacgag
     7321 gctggttgtt tcagctggaa tcctgtgtaa actggaatcc taaagaagta ggttccggca
     7381 gatgtgctgg caagtagtgc acacaggaaa agaagagcga gtcttcttct tccattggcc
     7441 ttatgtaggc ctccagcaga aggtgtcact gagatacata gatgtatcac catgcctgga
     7501 tttggagctt tctttgtccc acgttggcct tgaactcaga gatctggtta cctcgatctc
     7561 ctgtttttaa ggtcatgtac taccttgcct ggtcctaagc ttttcatggc cactatacct
     7621 caagatctgg atcaaaagca tgtgtcattt aaagtgagat atgggtcaga agcccatgtt
     7681 ctccagcctc aagatctgga tgacaggttt gacctccatt tctggattgt agttcattcc
     7741 agttgtagtc aagtcgacaa ccaggaatag ccatcacaac agatacgata gtacctacca
     7801 aagaaagcta agagagaaga atgagcctta atcgtagggc cctctcctgc aacagaagcc
     7861 gagaagagaa atcttgatat ttgtcctcag aaaaacatta tttgtcaaat atttgttgtt
     7921 ttagaagttt gtgagtttcc tgaaagcatt ttcatatgtt tcaaggatta cacccaagca
     7981 gaaaaactca aaatgtgtgc aaatagcatg tattttctaa tgatttattt tacttttatg
     8041 tactttgcca ttttgcttga ttgtgtgtct gtctgtgtga aggtgttgga tctcctggaa
     8101 ctatagagct agttgtaagc tgccctgtgg gtactgggat tgaacttggg ccctctggaa
     8161 gcccagccag tgctcttaac cactgaattg tgacaaggac cttagttggc cccaggacct
     8221 tagcacaact gagttaatga tggagtagta tcacatgagt aatacaattc agcatgtaaa
     8281 caatctcacc tcccaaaaca aaggcctaat ctatcaaaat ccgtaattct tggaaagtct
     8341 gtcagtgtac taaccttgct gtttggcttt tgtaggtctg cttcatgctg ttttgttttc
     8401 tgatatttgt caacccagaa catagttttt gtgcttaaaa gctccccctg agaaagaatc
     8461 agggctacac tggcatgcca aaccccaagt gtggtctctc atgggttatt aaagattttc
     8521 tattgactta aa
//
