LOCUS       XM_006237939            8589 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ubiquitin specific peptidase 45
            (Usp45), transcript variant X2, mRNA.
ACCESSION   XM_006237939
VERSION     XM_006237939.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051340.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006237939.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006237939.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8589
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..8589
                     /gene="Usp45"
                     /note="ubiquitin specific peptidase 45; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 19 ESTs, 4 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     98 samples with support for all annotated introns"
                     /db_xref="GeneID:313098"
                     /db_xref="RGD:1310976"
     CDS             136..2577
                     /gene="Usp45"
                     /codon_start=1
                     /product="ubiquitin carboxyl-terminal hydrolase 45 isoform
                     X1"
                     /protein_id="XP_006238001.1"
                     /db_xref="GeneID:313098"
                     /db_xref="RGD:1310976"
                     /translation="MRVKDPSKDLPEKGKRSKRPLLPHDEDSSDDIAVGLTCQHISYA
                     VSVNHVKKAVAETLWSVCSECLKERRLCDGQPVLPSDVWLCLKCGFQGCGKNSESQHS
                     LRHFKSSGAESHCVVISLSTWVIWCYECNEKLSTHCNKKVLAQIVDFLQKHVFKTQTD
                     AFSRIIKLCEEKREAGEIKKGKKGCAVPSVKGITNLGNTCFFNAVIQNLAQTYILFEL
                     MNEIKEDGTKFKISLSSAPQLEPLVVELSSPGPLTSALFLFLHSMKEAEKGPLSPKVL
                     FNQLCQKAPRFKGFQQQDSQELLHHLLDAVRTEETKRIQASILKAFNNPTTKTADEET
                     RKKVKAYGKEGVKMNFIDRIFIGELTSTVMCEECANISTMKDPFIDISLPIIEERVSK
                     PVLLGKMSKCRSLQETDQDHNKGTVTVENTHPPRAAKKHSSPKDKTLLSHDRKHLRKW
                     PSEEERTVGTHPNSENSEASPLAGILSNEASLNESPTEGSERDTSLESSVDADSEASE
                     PEVAYKPSVLLRSSGDPGAHGEQHPHLPLASELPHTKETHDCDEEMAEAMAELHLSGT
                     VTGNRDFHREKQPLNVPNNVCFSEGKHTKLHSAQNAFQTLSQSYVTTSKECSVQSCLY
                     QFTSMELLMGNNKLLCEDCTEKKRKCQKETSSAERKAGGVYTNARKQLLISAVPAILI
                     LHLKRFHQAGLSLRKVNRHVDFPLTLDLAPFCAATCKNISVGEKVLYGLYGIVEHSGS
                     MRGGHYTAYVKVRVPSRKLSECITGRKTAPGLKEADSELGGHWVHVSDTYVQVVPESR
                     ALSAQAYLLFYERIL"
ORIGIN      
        1 ctgcacaggc gcagaagctc ctgcgtgtgg aagctgcggc ccggcgggcg gggtgagttg
       61 gggcccaggc tttggggtca ctgcaacccc tgtgtcttcg cttaggcggt gaggcctttt
      121 tgtaggaaat aacagatgcg ggtaaaagat ccatccaaag atctacctga gaaaggcaaa
      181 agaagtaaaa gaccactgct acctcacgat gaagattctt cagatgacat tgctgtaggt
      241 ttaacatgcc agcacatcag ttatgctgtc agtgtgaacc atgtgaagaa ggcagtagct
      301 gagactctct ggtcagtttg ttcagagtgt ttgaaagaga gaagactctg tgatggacag
      361 ccggtacttc cttccgatgt ttggttgtgc ctcaagtgcg gttttcaggg atgcggtaag
      421 aactcagaaa gccagcattc actgagacac ttcaagagct ctggggcgga gtcccattgt
      481 gttgtcatta gcctgagcac atgggtcata tggtgttatg aatgtaatga aaaattatcg
      541 acacattgca acaagaaagt tttggctcag atagttgatt ttctccagaa acatgttttt
      601 aaaacacaaa cagatgcatt ttctagaatc ataaaacttt gtgaagaaaa acgtgaagca
      661 ggggaaataa agaaggggaa gaaaggctgt gctgtgccat ctgtcaaagg aattacaaac
      721 ttaggaaata cttgcttttt taatgccgtc atccagaact tggctcagac ttacattctt
      781 tttgaactga tgaacgagat aaaagaagat ggcaccaaat tcaagatttc tctttcgtca
      841 gctccacagc tggagccgtt agtggtggaa ctttcaagcc ctggaccatt gacttcagcc
      901 ttgttcctgt ttcttcacag catgaaggaa gctgaaaaag gaccactttc tcctaaagtt
      961 cttttcaatc agctctgtca gaaggctcct cgatttaaag gtttccagca acaggacagc
     1021 caggagcttc tgcaccattt gttggatgca gtgaggacag aggagacaaa gaggatacaa
     1081 gctagcattc taaaagcgtt caacaatcca actaccaaga ctgctgatga ggaaactaga
     1141 aaaaaagtca aagcctatgg aaaggaaggc gtgaagatga acttcataga tcggatcttc
     1201 attggcgaat taactagcac agtcatgtgt gaagaatgtg ctaacatctc taccatgaag
     1261 gatcccttca tagatatttc acttcctatc atagaagaaa gggtttcaaa acctgtactt
     1321 ttggggaaaa tgagtaaatg cagaagttta caggaaacag accaagatca taacaagggc
     1381 accgttacag tagaaaatac ccatccacca agagctgcca agaagcattc ctcacctaaa
     1441 gataagactc tgctaagtca tgacagaaaa catttaagaa aatggccgtc tgaagaagag
     1501 agaactgttg gtacacatcc gaacagtgaa aactcggaag ccagcccttt ggccggcatc
     1561 ctcagcaatg aggcatcgct gaacgaaagc cccactgagg gcagtgagag agacaccagc
     1621 ctagaaagca gtgtggatgc ggacagcgag gcttctgaac ccgaggtggc ttacaagccg
     1681 tctgtgctgc tccgatccag tggtgatccc ggcgcgcacg gggaacagca cccacacctc
     1741 ccactggcaa gtgaattgcc acacaccaag gagacgcacg actgcgatga ggaaatggcg
     1801 gaagcgatgg ctgagcttca tttgagcggc actgtaactg gaaatagaga ttttcacagg
     1861 gaaaaacagc cactaaatgt cccaaataat gtgtgttttt cagagggaaa acatacgaag
     1921 cttcacagtg cccaaaatgc ttttcagact ctttctcaga gctatgtaac tacttctaaa
     1981 gaatgctcag ttcagtcctg tctctaccag ttcacatcca tggagttact aatgggcaac
     2041 aacaagctgc tctgtgagga ctgcactgaa aagaaacgga agtgccaaaa ggaaaccagt
     2101 tctgcagaaa ggaaggcagg aggagtttat actaatgcca ggaagcaact actcatatct
     2161 gctgttccag ctatcctaat ccttcatctt aaaaggttcc accaggctgg cttgagtctt
     2221 cgtaaagtaa acagacatgt agacttcccg cttacccttg acttagcacc gttctgtgct
     2281 gctacctgta agaatataag tgtgggggag aaggttctct atggtctcta cggtatagtg
     2341 gagcacagcg gctcaatgag aggaggccac tacactgctt acgtgaaggt gcgagtgccc
     2401 tccaggaagc tgtccgagtg catcaccggg aggaagactg caccaggttt gaaagaagct
     2461 gatagtgaat tgggaggcca ctgggtccat gtcagcgaca cttatgtgca agtggttcca
     2521 gaatcaagag cactgagtgc gcaagcttat ctcctttttt atgaaagaat attataatta
     2581 tctgttaatt gttatttagt tcatttttat tttaatgctg aagtcgtaac tgtaatatgt
     2641 aatgtgcctt tgtagtctgt agaaatagtg cgtccttcca gtgttactta actttgtcga
     2701 tatgcagtga atcctttaaa gaaattaatt aatgtgacag gcagttgtgg tgctcgcctt
     2761 tattccagca cttggaaggc agaggcaggc agatctgtga aaaaccttgt cttgaaaaat
     2821 aaaacaaaaa agtaattaat gctttcaaat ctatattctt aagtgtagaa acatgtttta
     2881 tgttaatttt catgtccatg gagattgcca ctcaccacca aaaaaaaaaa gaaaagaaag
     2941 aaaaagttga tggtagtgga gagatcccct tcgcgacgtg actcgtcact acagacattc
     3001 agagacgatg ctggatcggg tctctagtgg atccttctcg agtggacgca gtgtatcttg
     3061 tgcttacttt tgttttagcc ttttacaatc tcggccctgt tttgaatcac tcttcacatt
     3121 tctctgtgcg tgtcattttt ctagtaaaca ttggtgtaag tttataacta tgaaagaaaa
     3181 attgcccatc cttgcaccac cccacttaaa atcatctcag ggctttgcag tggttggtgt
     3241 gtgtgttagt cgatgggaaa agtttctaga acagtctgaa ctagtgccta atgtaacata
     3301 ataatttttt catattttat gtgactcagt agtatgaaaa ggaaccattg taattttggt
     3361 actgtgagtt tacaagtaat aaattgattc gcttatcgcc ttgaatattt gaagatattg
     3421 agacatttca taaactaatc atttgcaatc ctttaaagac agtttgcaag tgattggtta
     3481 aggccaaaat aaaaatatag agaattttga cacatagaac tagcatatag aagttggtgg
     3541 tctatatagg aacataggat actttaaagt ttaaggatgt ctttgaacta taaactacca
     3601 aactatattt atgagtggta gaaatcatat tcttataatt aacaacaaat ataatacttt
     3661 ttttacttct gtacattaat aaatgttaaa tatggttttg tcttcataag cattatttga
     3721 aaagacaggt ggctagttgg ggatgtagtt caatggcaga gaacttgctt ggcctgtgta
     3781 aggtcctggt tccatcccca gacacacgaa taaaacattc aggtcaattt ggctttgact
     3841 ttaatggggc acagagctgc tacttctgtt ccctttaaat acgtagaaac acaggagagt
     3901 ttctccttcc aaaattcaaa gaattgaact gtgaaaactt agcatgaaaa atattactac
     3961 gaagatttta aataatcaat gaaatggttc agtgatacat agtattaaag caagatgtaa
     4021 gggaacgggt ccagcgtctt agtcttcagt gcctgtgttt gattcaatgg gcaaatgtag
     4081 gggagagagg ctgtaagctg tacagacctt tagccagcgt cgagccttct tggcatgtgt
     4141 aacataaggt caccttatga tgatgcctct taatatgcgg cggctaggtg aaactgattt
     4201 gtctaatgga gaaattttaa aataccatgg cataacttct atttttaagt tgcagaggaa
     4261 ttttcaatag tattttaaag atttttttgt attgaagata aagaactata ttttatctgt
     4321 agagcccagt tgtgtcctct aaaaagaact ttccagtgtc ttctgtttca tcagacattc
     4381 agagtttatt aatctattga cacgaaatag tctagcacca gagcaatgag ctagaaaaat
     4441 ttgctcaagt cggcttctca ttcatagcag ttgccccacc aaacaaatgt aaatagttaa
     4501 cctttttttc tctctctcct agaaaagata ctattaagag gtgtacagtc taggcaggtt
     4561 ccaatacctg gcatatgaca gtattttatc accctttaaa acagaaaaac ctgccgaggg
     4621 tggtggtgca cgcctcagac tcagcactcg ggaggcagag gcaggtgcat ttgagttcca
     4681 gggcacccaa ggctacacag agaaaccctg tctcaaaaca cttgaagaga aaagaagcac
     4741 cctaaaatct atatatgatt tttatacatt atcctagtag tgacgtgcag ataaaatgtt
     4801 catttattac ctagtgctaa ggagattctg aaatgcattt ttatgaccta aagtttgttt
     4861 tttcttgcca tctaaaaatg gagaaaaatg gtttgatttt gatacctagg agtttcctat
     4921 caagcttatg ttgtagataa aaatcacaca gatgtacact taaatttttg ttcttatttt
     4981 gaagttttcc aaagcacatt tgtagaaatt ttaaattgcg aggctactgt actaacaata
     5041 gtttccagat tacctcagga aacagtgcaa ataaacaaga atgtttacag atcaacaaaa
     5101 ctactcggtg ttttggcaca gtgaatttga aaggtaaaag agagaagttt ttatccagaa
     5161 actggtttac agggtaaacc caattctccc ctggctctcc cgtatttaaa atgatgtgcc
     5221 aattatgtga atgtttgtga cataaacaaa tgtacatcta tatttaagat ttattgttta
     5281 atgttttaaa aaataatatg aagactgctt ctgtaggtag tcaaggagat gatcatcgta
     5341 gcagctcaga gtcgtatatc aacagagcta ttttaccata tctaataatc cttagcttgc
     5401 atgtgtgatt cattagtgat tttatacagt agttgaataa aattttctga agacttagct
     5461 gtgaaatgtc accgcacatc aaatttttta gtacacaata gcatcctgcc tactttcatg
     5521 aactttatac tcagcatatt tttctgcatg acatctggtc caataaacct taaccaagtc
     5581 tgtgcactaa aaccaagctt tcagagagca tccattgcat tattggagaa attatttctg
     5641 tactaaactg gttttgttca tgtagaaatc atcagttcaa ctgtgtttaa aagatgatta
     5701 tttttgggta tcaataataa attcctagta tcattccttc tcttttatcc aattttacag
     5761 tattttaaaa atatctatgt aacttattga tcattatttg gccattgctg tatatataaa
     5821 catcctaata aatatgaaat tcttatgtta gcagattagg cctggagctt tgcattatac
     5881 attattgaca ggatattaat aaacattgtg ttcatatcta ttttagtccc ctggctttct
     5941 ataaacaaaa tataatttaa gaagcttatg aacaacaaaa atttatttcc tttactttta
     6001 gcaaccagga agctcaagac aaagacaaac agatccattt tccaaatgag gctctggtga
     6061 tcctctctga gcgttcacct ggttactagg gaaagggagc agtagggtcg cctttatgag
     6121 ggcttcacgt cagaacctaa tcactttcta aatactccag tcacagaact ctcacctggg
     6181 gagcttgcga atgggacaca aacatttagc tcacagtgac cttcaagttt caggaatgcg
     6241 ctatttaaaa aaaaaccttg tcaccaaccc gatgctggag attgtatcta gtagttcttc
     6301 cacccagcta cattctcagt ccagaaacca aacagacctg tcagctattt ccctgaaagg
     6361 tttgagttac ttagatagga ttgtacacta agaaatatgt tgtctacatg tctgcttctt
     6421 taactttttt agagccatga agcttccaga gattttgagg aaagttagat atttttcttt
     6481 tagagtgtat aaagatgggt ttattgctct tgggcaggtt ctgatcccaa gagtgaggcc
     6541 agggaagttg ccatagggag ggagacagaa gggaggtaga tgagaaagag aaagagtgtg
     6601 tgcattcagg gaaaggaaaa gcacagaagg agaggggtag ggggagaggg agaaagttac
     6661 atacttaaca tttttatttg atcatttaac aagtgtttgt tgaatacctg ctctttgctt
     6721 ggcattaggg atatagcagt gaatgcaaga aatcactcaa gaagaagact gtcaagtgag
     6781 tgtactggtc ttcgtttcag tttcttttgc tgtgatgaaa catcataacc acaagcaact
     6841 aggagaggag aaggtttatt tcatttacat ttgcatatca cagagggagt gggggcagga
     6901 tgtgatgcag aggctgggga gtgctgctta ctggcttact ctccatgttg tctccagttg
     6961 gctttctaaa gaaccaaagt ccaggccagg ggtagcatca ctcacaatgc tctggaacct
     7021 tccacatcaa tcacttattt gacagtgccc aaaagacttg cctagagccc catctaatag
     7081 aggcattttc tcaattgagg ctcctttctc tcctctgaat ctagctgtgt caagttgaca
     7141 taaaactagc tggcacataa ggggaaaaaa aacccaaata atactgctta cgtgctgttg
     7201 ggagtaacac ctagcaaaga aggatgttcc agtgaggcac agaacttatg ggatatctat
     7261 atagtaagta ttaagggaat ttattgtaag gacttatagt cttcagtcca actaacccaa
     7321 cagtgggcag ccatgaatag gaactccagg aatctagtag ttgctcagtc ccacgaggct
     7381 ggttgtttca gctggaatcc tgtgtaaact ggaatcctaa agaagtaggt tccggcagat
     7441 gtgctggcaa gtagtgcaca caggaaaaga agagcgagtc ttcttcttcc attggcctta
     7501 tgtaggcctc cagcagaagg tgtcactgag atacatagat gtatcaccat gcctggattt
     7561 ggagctttct ttgtcccacg ttggccttga actcagagat ctggttacct cgatctcctg
     7621 tttttaaggt catgtactac cttgcctggt cctaagcttt tcatggccac tatacctcaa
     7681 gatctggatc aaaagcatgt gtcatttaaa gtgagatatg ggtcagaagc ccatgttctc
     7741 cagcctcaag atctggatga caggtttgac ctccatttct ggattgtagt tcattccagt
     7801 tgtagtcaag tcgacaacca ggaatagcca tcacaacaga tacgatagta cctaccaaag
     7861 aaagctaaga gagaagaatg agccttaatc gtagggccct ctcctgcaac agaagccgag
     7921 aagagaaatc ttgatatttg tcctcagaaa aacattattt gtcaaatatt tgttgtttta
     7981 gaagtttgtg agtttcctga aagcattttc atatgtttca aggattacac ccaagcagaa
     8041 aaactcaaaa tgtgtgcaaa tagcatgtat tttctaatga tttattttac ttttatgtac
     8101 tttgccattt tgcttgattg tgtgtctgtc tgtgtgaagg tgttggatct cctggaacta
     8161 tagagctagt tgtaagctgc cctgtgggta ctgggattga acttgggccc tctggaagcc
     8221 cagccagtgc tcttaaccac tgaattgtga caaggacctt agttggcccc aggaccttag
     8281 cacaactgag ttaatgatgg agtagtatca catgagtaat acaattcagc atgtaaacaa
     8341 tctcacctcc caaaacaaag gcctaatcta tcaaaatccg taattcttgg aaagtctgtc
     8401 agtgtactaa ccttgctgtt tggcttttgt aggtctgctt catgctgttt tgttttctga
     8461 tatttgtcaa cccagaacat agtttttgtg cttaaaagct ccccctgaga aagaatcagg
     8521 gctacactgg catgccaaac cccaagtgtg gtctctcatg ggttattaaa gattttctat
     8581 tgacttaaa
//
