LOCUS       NM_001107418            4722 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ubiquitin specific peptidase 38 (Usp38), mRNA.
ACCESSION   NM_001107418 XM_001073885 XM_003751862 XM_003753096 XM_226362
VERSION     NM_001107418.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4722)
  AUTHORS   Quesada,V., Diaz-Perales,A., Gutierrez-Fernandez,A., Garabaya,C.,
            Cal,S. and Lopez-Otin,C.
  TITLE     Cloning and enzymatic analysis of 22 novel human ubiquitin-specific
            proteases
  JOURNAL   Biochem Biophys Res Commun 314 (1), 54-62 (2004)
   PUBMED   14715245
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000019.1 and AI112444.1.
            
            On or before Aug 2, 2019 this sequence version replaced
            XM_003751862.4, XM_003753096.4, NM_001107418.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.178012.1,
                                           SRR21887623.644510.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1196              JAXUCZ010000019.1  43910474-43911669
            1197-1332           JAXUCZ010000019.1  43913064-43913199
            1333-1462           JAXUCZ010000019.1  43919381-43919510
            1463-1564           JAXUCZ010000019.1  43922351-43922452
            1565-1723           JAXUCZ010000019.1  43927132-43927290
            1724-1917           JAXUCZ010000019.1  43929583-43929776
            1918-2011           JAXUCZ010000019.1  43933486-43933579
            2012-2118           JAXUCZ010000019.1  43935509-43935615
            2119-3478           JAXUCZ010000019.1  43936796-43938155
            3479-4705           JAXUCZ010000019.1  43940642-43941868
            4706-4722           AI112444.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..4722
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q11"
     gene            1..4722
                     /gene="Usp38"
                     /note="ubiquitin specific peptidase 38"
                     /db_xref="GeneID:307764"
                     /db_xref="RGD:1311974"
     exon            1..1196
                     /gene="Usp38"
                     /inference="alignment:Splign:2.1.0"
     CDS             515..3640
                     /gene="Usp38"
                     /EC_number="3.4.19.12"
                     /note="ubiquitin specific protease 38"
                     /codon_start=1
                     /product="ubiquitin carboxyl-terminal hydrolase 38"
                     /protein_id="NP_001100888.2"
                     /db_xref="GeneID:307764"
                     /db_xref="RGD:1311974"
                     /translation="MDKILEGLVSSSHPLPLKRMIVRKVVESAEHWLDEAQCEAMFDL
                     TTRLILEGQDPFQRQVGHQVLEAYARYHRPEFESFFNKTFVLGLLQQGYHSLDRKDVA
                     ILDYIHNGLKLIMSCPSVLDLFSLLQVEVLRMVCERPEPLLCARLSDLLTDFVQCVPK
                     GKLSITFCQQLVRTIGHFQCVSTQEKELREYVSQVTKVSNLLQNIWKAEPSTLLPSLQ
                     EVFASISSTDASFEPSVALASLVQHIPLQMITVLIRSLTTDPNVKDASMTRALCRMID
                     WLSWPLAQHVDTWVIALLKGLAAVQKFTILIDVTLLKIELVFNRLWFPLVRPGALAVL
                     SHMLLSFQHSPEAFHVIVPHIVNLVHSFRSDGLPSSTAFLVQLTELVHCMMYHYSGFP
                     DLYEPILEAVKDFPKPTEEKIKLILNQSAWTSQSNALASCLSRLSGKSETGKTGLINL
                     GNTCYMNSVLQALFMATEFRRQVLSLNLNGCNSLMKKLQHLFAFLAHTQREAYAPRIF
                     FEASRPPWFTPRSQQDCSEYLRFLLDRLHEEEKILRIQSSHKPSEGLGCTETCLQEVT
                     NKVAVPSESPSTGGSEKTLIEKMFGGKLRTHICCLNCRSTSHKVEAFTDLSLAFCPSP
                     SVEDSSFQDPASLPSAQDDGLMQTSVTDAEEEPVVCNPAAAAFVCDSVVNERRLGSPP
                     VEFPCAKNSSVPGESAKILVSKDVPQNPGGESTTSVTDLLNYFLAPEVLTGENQYYCE
                     SCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRTS
                     LSSLSEGWSADADFTDVNENLAKKLKPSGTEEAFCPKLVPYLLSSVVVHSGVSSESGH
                     YYSYARNITGTESSYQMRPQSESLSLTPSQSSLLGGESPNTVIEQDLENKEMSQEWFL
                     FNDSRVTFTSFQSVQKITSRFPKDTAYVLFYKKQSRTNGVRSDNPASGVWVNGEPPLQ
                     KELMDAITKDNKLYLQEQELNARARALQAASASCSFRPNGFDDNDPPGSCGPTGGGGG
                     GGFNAVGRLVF"
     exon            1197..1332
                     /gene="Usp38"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..1462
                     /gene="Usp38"
                     /inference="alignment:Splign:2.1.0"
     exon            1463..1564
                     /gene="Usp38"
                     /inference="alignment:Splign:2.1.0"
     exon            1565..1723
                     /gene="Usp38"
                     /inference="alignment:Splign:2.1.0"
     exon            1724..1917
                     /gene="Usp38"
                     /inference="alignment:Splign:2.1.0"
     exon            1918..2011
                     /gene="Usp38"
                     /inference="alignment:Splign:2.1.0"
     exon            2012..2118
                     /gene="Usp38"
                     /inference="alignment:Splign:2.1.0"
     exon            2119..3478
                     /gene="Usp38"
                     /inference="alignment:Splign:2.1.0"
     exon            3479..4706
                     /gene="Usp38"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acttcctatt tgccggtatt tctgcttccg ggttaagggt gttcggcgct tccagctcct
       61 ctccttggca gatcgaggta ctctggttga cagcgcctcc tgactcaacc gagggcggct
      121 ttttactgcc cacccgcgga cgtctggacg cctcacaacc ccgggacgcg aaggcgctcc
      181 tcaccttcca gctcagcctg gaggcctgga gggtccctgt gcccgaatgc tgagaggggt
      241 cgcgggccca gcgaggcagc cgtgtgcgga cctccggctc cttaggcgga ccgcggggac
      301 tgacagcctt tcggcgcccc agaatcgccc gctcccgtcc cagctcggat gggccttccc
      361 actcgataaa tgtggctgct gaggcagcgg tggcggtggc cagacctgct gctgcttggc
      421 ttcaagttca cccccaccgc ggctccttgg tgtccccccg ggctgccgcc gccagctcct
      481 tatcccctgg gcctggcctt gcagagtggc gacgatggac aagattctgg agggtctggt
      541 gagttcctcg cacccgctgc ccctcaagcg gatgattgtg cggaaggtgg tggaatccgc
      601 ggagcattgg ctcgacgagg cgcagtgcga ggccatgttt gacctgacga cccgcctcat
      661 cctggagggc caggacccct tccagcgaca agtgggccac caggtgctgg aggcctacgc
      721 gcggtaccac cggccggagt tcgagtcctt cttcaacaag actttcgtgt tgggcctcct
      781 tcagcagggc taccactcac tggacaggaa ggacgtagcc atcctggact acattcacaa
      841 cggcctgaag ctgattatga gctgcccgtc ggtgctggac ctcttcagcc tgttacaggt
      901 ggaggtctta cgaatggttt gcgagaggcc ggagccacta ctctgtgcca ggctgagcga
      961 cctcctgacg gatttcgtgc agtgcgtccc caaagggaaa ctgtccatta ccttctgtca
     1021 acagctggtt cggacgatag gtcacttcca gtgtgtgtcc acccaggaga aggagctccg
     1081 ggagtatgtc tcccaggtaa caaaagtgag taacttacta cagaatattt ggaaggctga
     1141 gccctccacg ctgctacctt ctctgcaaga agtttttgca agcatctctt ccacagatgc
     1201 gtcctttgag ccctcggtgg ccttggcaag cctggtgcag catattcctc tgcagatgat
     1261 cacggtcctc atcaggagcc tgaccaccga cccaaacgtg aaggatgcaa gcatgacccg
     1321 agctctctgc agaatgattg actggctgtc ctggccattg gctcagcatg tggatacatg
     1381 ggtaattgct ctcctgaagg gactggcagc tgttcagaag tttactattt tgatagatgt
     1441 tactttgctg aaaatagaac tggtttttaa tcgactttgg tttcctcttg tgagacctgg
     1501 tgctcttgca gtcctctctc atatgctgct tagttttcag cattctccag aggcattcca
     1561 tgtgattgtc cctcatatag ttaacttggt tcactccttc agaagtgatg gcctgccttc
     1621 cagcacagcc ttcttagtgc agttaacaga gctggttcac tgtatgatgt accattattc
     1681 tgggtttcca gatctctatg agcctattct ggaggcggtg aaggattttc ctaagcccac
     1741 tgaagagaag attaagttga ttctcaatca aagtgcctgg acttctcaat ccaacgcttt
     1801 ggcatcttgc ttgtctagac tttctggaaa atctgaaact gggaaaactg gtcttattaa
     1861 cctgggaaac acgtgttaca tgaacagtgt tttacaagca ttgtttatgg ctacagagtt
     1921 cagaagacaa gtattatctt taaatctaaa tgggtgtaat tccttaatga aaaaattaca
     1981 acatcttttt gcttttttgg ctcatacaca aagggaagca tacgcacctc ggatattttt
     2041 tgaggcttcc agacctccgt ggtttactcc caggtcacaa caggattgct ctgagtacct
     2101 caggtttctg ctggacagac tccatgaaga agaaaagatc ttacgaattc agtcctcaca
     2161 taagccttct gaaggtctgg gctgtactga aacttgttta caagaagtaa ccaataaggt
     2221 agctgtgccc tcagagtccc ctagcacagg tggcagtgag aagactctaa tagagaaaat
     2281 gtttggaggg aaactacgga ctcacatctg ctgcctgaac tgcaggagta cctcacacaa
     2341 agtggaagcc ttcacagatc tttcgctagc cttctgtcct agcccttctg tggaagactc
     2401 gtctttccaa gacccagctt cgctacccag tgcacaagat gatgggctaa tgcaaaccag
     2461 tgtcactgac gcagaagaag agccagtagt ttgtaaccca gcagcagctg cctttgtttg
     2521 tgactcagtt gtgaatgaaa gacgattggg cagtcctcct gttgagtttc cctgtgccaa
     2581 aaactcttct gtccctgggg aatctgcaaa gattcttgtc agtaaagatg tacctcagaa
     2641 cccaggaggt gagagcacaa cttcggtgac tgacttactg aactactttt tggctcccga
     2701 ggttctgact ggtgagaacc aatattactg tgagagctgt gcctctctac agaatgcaga
     2761 gaagactatg cagatcacag aggagcctga gtaccttatc cttacgctcc tgagattctc
     2821 ctatgatcag aagtaccacg tgagaagaaa gattttagac aatgtgtcac tgccgctggt
     2881 tttggagttg cccgttaaaa ggacttccct ctcttccttg tcggaaggtt ggtctgcaga
     2941 tgctgacttc actgatgtta atgagaacct agctaaaaaa ttaaaacctt ctgggactga
     3001 agaagctttc tgccccaaat tagtgcccta cctattaagt tctgttgttg tgcactctgg
     3061 tgtgtcctct gaaagtggcc attactattc ttatgccaga aacatcacag gtacagagtc
     3121 ttcctaccag atgcgccccc agtctgaaag tctgtcatta acaccctccc agagtagttt
     3181 attaggggga gaaagcccca atacagtcat tgaacaggac ttggaaaata aggaaatgtc
     3241 acaagagtgg tttttattta atgacagcag ggtgacattt acttcatttc agtcagtcca
     3301 gaaaatcaca agtaggtttc caaaagacac agcgtacgtg cttttctaca aaaagcaaag
     3361 cagaactaat ggtgtacgca gtgacaatcc agccagtggc gtctgggtca atggagagcc
     3421 accactacag aaagagctca tggatgccat aacaaaggac aacaaactgt atttgcagga
     3481 acaagaattg aatgctcgag cccgggccct acaagctgcg tcagcgtcat gctcctttcg
     3541 gcccaatgga tttgacgaca atgacccacc aggaagctgt gggccgacgg gtggaggggg
     3601 cggaggagga tttaacgcag ttggcagact cgtcttttga ccctgagaga actgaaaatg
     3661 catctggtca ccaaacatcc gatactgtgg ctgttaaaat gttaggctgt gacctagagc
     3721 atatctagct tttatttttc ttttcattag acccaaatac ttaagaaaat acactcagtg
     3781 gttgttttta ttttcttgac aaaaatgcat catggaaaaa aaaaatctac ctcttaaact
     3841 tccatttgca tttatggtta gacatgcttg gccaaaagtg ttgagaggaa aaggcatacc
     3901 tggtctctaa ttaagctcat taaatttggt agaaggattg aaatggtgta ttttacttgt
     3961 actgaacaaa ataattcatt ttgcattctt ataagaattg atgctagata tatatcttgt
     4021 tttaagaaaa atgaaagtct tcgtttctgg cataattacc ccaatattaa attcaagtct
     4081 ctgtggagtc gataccacgc tccgccccag ctgccagtct ctgggctgct gtccgtctcc
     4141 tcggcattgt gctccagatt gaggaacaag tgtcatttaa aggatcatct acaccacaca
     4201 tggcaagtga tttacggaag gtgcatgatg ccgtaggcag tgtttttaac ccaactctgt
     4261 agtatttcca gttgtccaag gactttaaaa tcctgtttca gggagggcat ctcctgtgtg
     4321 ttttaaagga gctgagtcct gtatgtgcct tgcagtactg taattcaaaa atagctttgg
     4381 ctgctgaaag ttttctaaaa caaaatgtta ggaagtaatt ttgtgctaac attaaaatta
     4441 ttttttaaag gtattagatt ttttcagaag taaaatcttg gtggtcctaa actagtaaat
     4501 gtaatggtaa atttctaact cttagaaaaa ttcagaggaa atgaagctag tttaagtaca
     4561 aaatctttga tttgttattt aatcttcaca ttaaacattg ataacatttt tagagttgta
     4621 tatatgggtt tttttccctt taagacacat gccttacaca taaaatataa tctgcttcat
     4681 aaaatattaa aatgtcacac cccacaaaaa aaaaaaaaaa aa
//
