LOCUS       NM_019379               3845 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus USO1 vesicle transport factor (Uso1), mRNA.
ACCESSION   NM_019379
VERSION     NM_019379.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3845)
  AUTHORS   Wang,T., Grabski,R., Sztul,E. and Hay,J.C.
  TITLE     p115-SNARE interactions: a dynamic cycle of p115 binding monomeric
            SNARE motifs and releasing assembled bundles
  JOURNAL   Traffic 16 (2), 148-171 (2015)
   PUBMED   25406594
  REMARK    GeneRIF: Monomeric SNAREs are a major binding site for p115 on
            COPII vesicles, and that p115 dissociates from its SNARE partners
            upon SNAREpin assembly.
REFERENCE   2  (bases 1 to 3845)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3845)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 3845)
  AUTHORS   Kim,S., Hill,A., Warman,M.L. and Smits,P.
  TITLE     Golgi disruption and early embryonic lethality in mice lacking USO1
  JOURNAL   PLoS One 7 (11), e50530 (2012)
   PUBMED   23185636
REFERENCE   5  (bases 1 to 3845)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   6  (bases 1 to 3845)
  AUTHORS   Lowe,M., Rabouille,C., Nakamura,N., Watson,R., Jackman,M.,
            Jamsa,E., Rahman,D., Pappin,D.J. and Warren,G.
  TITLE     Cdc2 kinase directly phosphorylates the cis-Golgi matrix protein
            GM130 and is required for Golgi fragmentation in mitosis
  JOURNAL   Cell 94 (6), 783-793 (1998)
   PUBMED   9753325
REFERENCE   7  (bases 1 to 3845)
  AUTHORS   Nakamura,N., Lowe,M., Levine,T.P., Rabouille,C. and Warren,G.
  TITLE     The vesicle docking protein p115 binds GM130, a cis-Golgi matrix
            protein, in a mitotically regulated manner
  JOURNAL   Cell 89 (3), 445-455 (1997)
   PUBMED   9150144
REFERENCE   8  (bases 1 to 3845)
  AUTHORS   Barroso,M., Nelson,D.S. and Sztul,E.
  TITLE     Transcytosis-associated protein (TAP)/p115 is a general fusion
            factor required for binding of vesicles to acceptor membranes
  JOURNAL   Proc Natl Acad Sci U S A 92 (2), 527-531 (1995)
   PUBMED   7831324
REFERENCE   9  (bases 1 to 3845)
  AUTHORS   Sapperstein,S.K., Walter,D.M., Grosvenor,A.R., Heuser,J.E. and
            Waters,M.G.
  TITLE     p115 is a general vesicular transport factor related to the yeast
            endoplasmic reticulum to Golgi transport factor Uso1p
  JOURNAL   Proc Natl Acad Sci U S A 92 (2), 522-526 (1995)
   PUBMED   7831323
REFERENCE   10 (bases 1 to 3845)
  AUTHORS   Waters,M.G., Clary,D.O. and Rothman,J.E.
  TITLE     A novel 115-kD peripheral membrane protein is required for
            intercisternal transport in the Golgi stack
  JOURNAL   J Cell Biol 118 (5), 1015-1026 (1992)
   PUBMED   1512287
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            On Nov 26, 2020 this sequence version replaced NM_019379.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U15589.1, U14192.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760393 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-162               JAXUCZ010000014.1  16216228-16216389   c
            163-249             JAXUCZ010000014.1  16203600-16203686   c
            250-314             JAXUCZ010000014.1  16203226-16203290   c
            315-391             JAXUCZ010000014.1  16196673-16196749   c
            392-492             JAXUCZ010000014.1  16187880-16187980   c
            493-595             JAXUCZ010000014.1  16187376-16187478   c
            596-651             JAXUCZ010000014.1  16187179-16187234   c
            652-772             JAXUCZ010000014.1  16183321-16183441   c
            773-951             JAXUCZ010000014.1  16179537-16179715   c
            952-1092            JAXUCZ010000014.1  16176514-16176654   c
            1093-1181           JAXUCZ010000014.1  16174146-16174234   c
            1182-1336           JAXUCZ010000014.1  16173545-16173699   c
            1337-1548           JAXUCZ010000014.1  16172437-16172648   c
            1549-1659           JAXUCZ010000014.1  16165962-16166072   c
            1660-1778           JAXUCZ010000014.1  16165587-16165705   c
            1779-1960           JAXUCZ010000014.1  16165285-16165466   c
            1961-2082           JAXUCZ010000014.1  16164034-16164155   c
            2083-2221           JAXUCZ010000014.1  16160822-16160960   c
            2222-2385           JAXUCZ010000014.1  16159485-16159648   c
            2386-2472           JAXUCZ010000014.1  16157924-16158010   c
            2473-2571           JAXUCZ010000014.1  16155224-16155322   c
            2572-2679           JAXUCZ010000014.1  16153793-16153900   c
            2680-2895           JAXUCZ010000014.1  16152375-16152590   c
            2896-3845           JAXUCZ010000014.1  16150923-16151872   c
FEATURES             Location/Qualifiers
     source          1..3845
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..3845
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /note="USO1 vesicle transport factor"
                     /db_xref="GeneID:56042"
                     /db_xref="RGD:621604"
     exon            1..162
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..2976
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /note="protein USO1 homolog; vesicle-docking protein;
                     transcytosis-associated protein; vesicle docking protein,
                     115 kDa"
                     /codon_start=1
                     /product="general vesicular transport factor p115"
                     /protein_id="NP_062252.2"
                     /db_xref="GeneID:56042"
                     /db_xref="RGD:621604"
                     /translation="MNFLRGVMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVR
                     ALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIAYALDTLYNIISNDEEEEVEENS
                     TRQSEDLGSQFTEIFIKQPENVTLLLSLLEEFDFHVRWPGVRLLTSLLKQLGPPVQQI
                     ILVSPMGVSKLMDLLADSREIIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIIT
                     EEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKAWFEVGDENPGWSAQK
                     VTNLHLMLQLVRVLVSPTNPPGATSSCQKAMFQCGLLQQLCTILMATGIPADILTETI
                     NTVSEVIRGCQVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCF
                     LYKNEKGQGEIVATLLPSTIDATGNSVSAGQLLCGGLFSTDSLSNWCAAVALAHALQG
                     NATQKEQLLRVQLATSIGNPPVSLLQQCTNILSQGSKIQTRVGLLMLLCTWLSNCPIA
                     VTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNSLENYTKEKLKQ
                     LIEKRIGKENYIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVI
                     TKAIYKSSEEDKKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELKQQVSTLKCQNEQ
                     LQTAVTQQASQIQQHKDQYNLLKVQLGKDNHHQGSHSDGAQVNGIQPEEISRLREEIE
                     ELRSHQVLLQSQLAEKDTVIENLRSSQVSGMSEQALATCSPRDAEQVAELKQELSALK
                     SQLCSQSLEITRLQTENSELQQRAETLAKSVPVEGESELVTAAKTTDVEGRLSALLQE
                     TKELKNEIKALSEERTAIQKQLDSSNSTIAILQTEKDKLYLEVTDSKKEQDDLLVLLA
                     DQDQKILSLKSKLKDLGHPVEEEDESGDQEDDDDELDDGDRDQDI"
     exon            163..249
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            250..314
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            315..391
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            392..492
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            493..595
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            596..651
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            652..772
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            773..951
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1092
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1181
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..1336
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1548
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1659
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            1660..1778
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            1779..1960
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            1961..2082
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            2083..2221
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            2222..2385
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            2386..2472
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            2473..2571
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            2572..2679
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            2680..2895
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
     exon            2896..3845
                     /gene="Uso1"
                     /gene_synonym="TAP; Vdp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggagagccg gctcgggggc taggcccttc gggggcgggg ggctgtcgtg ttttctttgg
       61 cggaggggct ggtgaagccg gcggctgagc gacgagatga atttcctccg cggggtgatg
      121 gggggtcaga gtgccggacc ccagcacaca gaagctgaga cgattcagaa gctctgtgac
      181 cgcgtagctt catctacttt actggacgac cgaagaaatg ctgtccgtgc ccttaagtca
      241 ctgtctaaga aataccgctt ggaagtggga atccaagcca tggagcatct tatccacgtc
      301 ttacagacag atcgttcgga ttctgaaata atagcgtatg ctttggacac actctataat
      361 ataatatcca atgatgaaga ggaagaagta gaagaaaatt ctacaagaca gagtgaggat
      421 ttgggaagcc aatttacaga aattttcatt aagcagccag aaaatgtcac tctcctgtta
      481 tctttgttgg aggagtttga tttccacgtc cgatggcctg gtgtgagact tctgacttct
      541 cttttaaaac agctagggcc tccagtgcag caaatcatcc tagtcagccc catgggtgtt
      601 tcaaaattaa tggacttgct ggcagattcc agggaaatta tacgtaatga tggcgtctta
      661 ctactgcagg cattaacaag gagcaacgga gcgatccaga aaattgttgc ttttgaaaat
      721 gctttcgaga gactactgga cattattaca gaggagggga acagcgatgg aggtatagta
      781 gtggaagatt gtttgatttt gctccaaaat ttgttaaaaa acaacaattc caatcaaaat
      841 ttttttaaag aaggctctta tattcaacgt atgaaagctt ggtttgaagt tggagatgaa
      901 aatcctggtt ggtcagcaca gaaagtgacc aatcttcatt taatgctcca gcttgtgcgg
      961 gtactggtgt ctcccaccaa ccctcccggt gctaccagta gctgccagaa ggccatgttc
     1021 cagtgtgggt tactacaaca gctttgcact atcctgatgg ctaccggaat tcctgctgat
     1081 atcctgactg agaccataaa tactgtatca gaagttattc gaggctgcca agtaaatcaa
     1141 gactactttg cttctgtgaa tgcgccttca aatcccccac gaccggcaat cgttgtgctg
     1201 ctcatgtcca tggtcaacga gaggcagcca tttgtactgc gctgcgccgt gctctactgt
     1261 ttccagtgct tcctctataa aaacgagaaa ggacaaggag agattgtggc cactctgcta
     1321 ccttccacta ttgacgcaac aggtaactcg gtctcagctg gccagctgct ctgcggaggt
     1381 ttgttttcca cagactccct ctcaaactgg tgtgctgccg tggccctcgc ccatgcactg
     1441 caagggaacg ccacccagaa ggagcagctg ctcagggttc agctggccac cagcatcggc
     1501 aaccccccag tgtcgctctt gcagcagtgc accaacattc tgtcccaggg aagcaagata
     1561 cagacaagag tcgggttgtt gatgttgctt tgtacctggt taagcaactg tccgattgct
     1621 gtaacacact ttcttcacaa ctcagccaat gttccatttc ttacaggaca gattgcagaa
     1681 aatctcggag aagaagagca gttggtccaa ggcttatgtg cccttctttt gggcatttca
     1741 atttatttca acgacaactc actagaaaac tacacgaaag agaaactaaa gcaactaata
     1801 gagaagagga ttggcaaaga gaattacata gagaaacttg gatttattag caagcatgag
     1861 ttatattcca gagcatctca gaaaccccag ccaaactttc cgagtccaga atacatgata
     1921 tttgatcatg agtttacaaa actggtgaaa gaacttgaag gtgttattac caaggctatt
     1981 tataagtcca gcgaagaaga taagaaagag gaagaggtaa agaaaacctt agaacagcat
     2041 gataatattg tgactcacta taagaatatg atccgtgagc aagacctaca actggaggaa
     2101 ctaaaacagc aagtgtccac actgaaatgt cagaacgagc agctgcaaac agcagtcacc
     2161 cagcaggctt ctcagattca gcagcacaag gatcagtaca acctcctcaa agttcagctc
     2221 gggaaagaca atcaccatca aggttctcac agtgacgggg ctcaggtaaa tggcattcag
     2281 ccagaggaaa tcagtcggct gagggaagag atagaagaat taagaagtca tcaggtgctc
     2341 ttacagagcc agctagctga aaaggacact gtgattgaaa atttgagatc ttcacaagtg
     2401 tctggcatga gtgaacaggc tttagcaacg tgttcaccca gagatgccga gcaagttgca
     2461 gagttaaaac aggaattgtc agcattaaag tcccagttat gttcacagtc tctggagatc
     2521 actagactcc agacagagaa cagtgagctg caacagagag cagagacctt ggcaaagtca
     2581 gttcctgtag aaggagagag tgagcttgtg acagccgcaa aaactacgga tgtagaggga
     2641 aggctgtctg ccctgctgca ggagaccaaa gagttaaaga atgagattaa agcattgtct
     2701 gaggagagga ccgccattca aaagcagctg gactcctcca acagcaccat cgccatccta
     2761 caaacggaga aagacaagct atacttggaa gttacggatt ctaagaaaga acaagatgat
     2821 cttttggtgc tgttggcaga tcaagatcag aaaatcctgt cactgaagag taaactcaag
     2881 gatcttggtc atccagttga agaagaagat gaatctggag accaagaaga tgatgatgat
     2941 gaacttgacg atggtgacag ggaccaggat atctagcttt aaaccctagg aacaatagag
     3001 attatgtcat tgtgttgaag aagtcttaag acagtgcttt ggcttgcctc cacaaaaaat
     3061 aaagacagaa ccaggtggaa agcattcact aataaaatta ttgatgtatg tttttaatat
     3121 tgccacccat gtgggaaact ctgacttcat gtggaagttt tatttatgtt cttctgaact
     3181 ctcccaaaat ttgcagaggg caccaggttc caaaaacaca gcatttgaag gcacgtggtg
     3241 gcagtgcagt tccttactgg ttcactggtc ggtcgcttgc tttcagacag agtctgggcc
     3301 ttcagtacta acatttgatt aatgtgtatt gaacgggaat cactatttct aaatcagcgt
     3361 ttgcattctc ggctgattaa tccttgtaaa gaaaggactg tacttaaaga cagggcagcc
     3421 ttgaatcagg ggtcctgtgt gtcatcaccc ccttccccac tgtgcctccc tggtgagcag
     3481 gatgggacag ttcagagtgc ttgccgtcca gcagggccac ctctgcctac tgagcggaaa
     3541 gactgtcccg gagtgtgaaa gcactctgag gagctggaac agtgtattaa cgtggctggt
     3601 tttctctctg ttaaagctaa agaaggaaac agattatagt cagcagttca tacagctggg
     3661 attagaattg tttgattatc acaaaacatg ttcttagttt tacaaaaacc caaactatga
     3721 tttatgtaat ttattggcat ttttgctgaa taggtgtaag tcagataata gatttttaaa
     3781 aagcaaatga agcaatgtgt caaagtctaa tgttttcata ataaaaatag atattatgtt
     3841 cactt
//
