LOCUS       NM_031139               2171 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus upstream transcription factor 2, c-fos
            interacting (Usf2), mRNA.
ACCESSION   NM_031139 XM_001079341
VERSION     NM_031139.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2171)
  AUTHORS   Wood,M.A., Mukherjee,P., Toocheck,C.A. and Walker,W.H.
  TITLE     Upstream stimulatory factor induces Nr5a1 and Shbg gene expression
            during the onset of rat Sertoli cell differentiation
  JOURNAL   Biol Reprod 85 (5), 965-976 (2011)
   PUBMED   21734262
  REMARK    GeneRIF: Upstream stimulatory factors (USF1 and USF2) induce Nr5a1
            and Shbg gene expression during the onset of rat Sertoli cell
            differentiation.
REFERENCE   2  (bases 1 to 2171)
  AUTHORS   Li,Y. and Wang,S.
  TITLE     Glycated albumin upregulates upstream stimulatory factor 2 gene
            transcription in mesangial cells
  JOURNAL   Am J Physiol Renal Physiol 299 (1), F121-F127 (2010)
   PUBMED   20410211
  REMARK    GeneRIF: Data suggest that glycated albumin upregulated USF2 gene
            transcription in mesangial cells through NF-kappaB-dependent
            transactivation of the USF2 promoter.
REFERENCE   3  (bases 1 to 2171)
  AUTHORS   Kim,K.S., Jung,H.S., Chung,Y.J., Jung,T.S., Jang,H.W., Lee,M.S.,
            Kim,K.W. and Chung,J.H.
  TITLE     Overexpression of USF increases TGF-beta1 protein levels, but G1
            phase arrest was not induced in FRTL-5 cells
  JOURNAL   J Korean Med Sci 23 (5), 870-876 (2008)
   PUBMED   18955796
  REMARK    GeneRIF: USF has a role in increasing TGF-beta1 protein levels, but
            not in indusing G1 phase arrest
REFERENCE   4  (bases 1 to 2171)
  AUTHORS   Shi,L., Liu,S., Nikolic,D. and Wang,S.
  TITLE     High glucose levels upregulate upstream stimulatory factor 2 gene
            transcription in mesangial cells
  JOURNAL   J Cell Biochem 103 (6), 1952-1961 (2008)
   PUBMED   17955499
  REMARK    GeneRIF: high glucose levels up-regulate USF2 gene transcription in
            mesangial cells through CREB-dependent transactivation of the USF2
            promoter.
REFERENCE   5  (bases 1 to 2171)
  AUTHORS   Park,K.Y. and Russo,A.F.
  TITLE     Control of the calcitonin gene-related peptide enhancer by upstream
            stimulatory factor in trigeminal ganglion neurons
  JOURNAL   J Biol Chem 283 (9), 5441-5451 (2008)
   PUBMED   18167349
  REMARK    GeneRIF: USF1 and USF2 are important contributors to
            neuronal-specific and mitogen-activated protein kinase regulation
            of the CGRP gene in trigeminal ganglion neurons
REFERENCE   6  (bases 1 to 2171)
  AUTHORS   Casado,M., Vallet,V.S., Kahn,A. and Vaulont,S.
  TITLE     Essential role in vivo of upstream stimulatory factors for a normal
            dietary response of the fatty acid synthase gene in the liver
  JOURNAL   J Biol Chem 274 (4), 2009-2013 (1999)
   PUBMED   9890958
REFERENCE   7  (bases 1 to 2171)
  AUTHORS   Kono,M., Takashima,S., Liu,H., Inoue,M., Kojima,N., Lee,Y.C.,
            Hamamoto,T. and Tsuji,S.
  TITLE     Molecular cloning and functional expression of a fifth-type alpha
            2,3-sialyltransferase (mST3Gal V: GM3 synthase)
  JOURNAL   Biochem Biophys Res Commun 253 (1), 170-175 (1998)
   PUBMED   9875239
REFERENCE   8  (bases 1 to 2171)
  AUTHORS   Viollet,B., Lefrancois-Martinez,A.M., Henrion,A., Kahn,A.,
            Raymondjean,M. and Martinez,A.
  TITLE     Immunochemical characterization and transacting properties of
            upstream stimulatory factor isoforms
  JOURNAL   J Biol Chem 271 (3), 1405-1415 (1996)
   PUBMED   8576131
REFERENCE   9  (bases 1 to 2171)
  AUTHORS   Lefrancois-Martinez,A.M., Martinez,A., Antoine,B., Raymondjean,M.
            and Kahn,A.
  TITLE     Upstream stimulatory factor proteins are major components of the
            glucose response complex of the L-type pyruvate kinase gene
            promoter
  JOURNAL   J Biol Chem 270 (6), 2640-2643 (1995)
   PUBMED   7852331
REFERENCE   10 (bases 1 to 2171)
  AUTHORS   Lin,Q., Luo,X. and Sawadogo,M.
  TITLE     Archaic structure of the gene encoding transcription factor USF
  JOURNAL   J Biol Chem 269 (39), 23894-23903 (1994)
   PUBMED   7523363
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB047556.1.
            
            On Jun 25, 2006 this sequence version replaced XM_001079341.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB047556.1, BC128735.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMN11044071
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2171
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..2171
                     /gene="Usf2"
                     /note="upstream transcription factor 2, c-fos interacting"
                     /db_xref="GeneID:81817"
                     /db_xref="RGD:620975"
     exon            1..573
                     /gene="Usf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             512..1552
                     /gene="Usf2"
                     /note="major late transcription factor 2; transcription
                     factor USF2"
                     /codon_start=1
                     /product="upstream stimulatory factor 2"
                     /protein_id="NP_112401.1"
                     /db_xref="GeneID:81817"
                     /db_xref="RGD:620975"
                     /translation="MDMLDPGLDPASSATAAAAASHDKGPEAEEGVELQEGGDGPGAE
                     EQTAVAIASVQQAAFGDHNIQYQFRTESNGGQVTYRVVQVTDGQLDGQGDAAGAVSVV
                     STAAFAGGQQAVTQVGVDGAAQRPGPAAASVPTGPAAPFPLAVIQNPFSNGGSPAAEA
                     VSGEARFAYFPASSVGDTTAVSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRT
                     HPYSPKIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCHADNSKTGASK
                     GGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQQ
                     HNLEMVGESTRQ"
     exon            574..620
                     /gene="Usf2"
                     /inference="alignment:Splign:2.1.0"
     exon            621..739
                     /gene="Usf2"
                     /inference="alignment:Splign:2.1.0"
     exon            740..940
                     /gene="Usf2"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1091
                     /gene="Usf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1179
                     /gene="Usf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1180..1238
                     /gene="Usf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1239..1333
                     /gene="Usf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1334..1462
                     /gene="Usf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1463..2161
                     /gene="Usf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tagaaagcgg cggcagctgc agccacgatc cgccgccgaa ccgggccagg ccgggcggcg
       61 gacgcgagaa ccgaggatct gggaaacagg gcggccgcca tccgggcagg gccgagttat
      121 aaaaaaaaat taaaaaaaaa ggaaggctca agtctcggcg gcggcggcgg caagcactca
      181 gggaagcagg ccccaggcgt gcggcggcgg ggcggcgggc ggcgagccgg ccggcgggcg
      241 ggcggggggc atctgaactg tggcccggag cctcgcgccg cccggaactg gcggcgggcg
      301 gagcggatgg aagaggcggc agctgcagga gtagcggcgg cggcggcggc ggcatctcct
      361 cctcacatga cccactgttt gtccccgtga tcagcgcgag gctcccgtgt ctcctccgtc
      421 ccctcctgcc gagcgggtga gcgccgggct cgggcccccc cggccgccct ctccctcccc
      481 tccctcccct cccctccccc ccgccccccc catggacatg ctggacccgg gtctggatcc
      541 cgcttcctcg gccaccgctg ctgccgccgc cagccacgac aagggacccg aggccgagga
      601 gggcgttgag ctgcaggaag gcggggacgg cccgggggct gaggagcaga cggcggtggc
      661 catcgccagc gtccagcagg cggcgttcgg cgaccataat atccagtacc agttccgcac
      721 agagagtaat ggaggccagg tgacataccg cgtagtccag gtgactgatg gtcagctgga
      781 cggccagggc gacgcggctg gcgccgtcag cgtcgtgtcc accgctgcct tcgcaggggg
      841 gcagcaggct gtgacccagg tgggtgtgga cggggcagcc cagcgccccg gccctgccgc
      901 tgcctctgta cccacaggtc ccgcagcacc cttcccgctg gctgtaattc aaaatccatt
      961 cagcaatggt ggcagcccag cagccgaagc tgtcagcggg gaggcacggt ttgcttattt
     1021 tccagcatcc agtgtcggcg ataccacagc tgtgtctgtt caaactacag accagagcct
     1081 acaggccgga ggccagttct atgtcatgat gacaccccag gatgtgcttc aaacaggaac
     1141 acagaggaca attgcacccc ggacacaccc ctattctccg aaaattgatg gaaccagaac
     1201 tcctcgagat gagagaagaa gagctcagca caatgaagtg gagcggagaa ggagggacaa
     1261 gatcaacaac tggattgtcc agctttcaaa aatcattcca gattgtcatg cagacaacag
     1321 caagacaggg gcgagtaaag ggggcatcct gtccaaggct tgcgattaca tccgggagct
     1381 acgccagacc aaccagcgta tgcaggagac cttcaaggag gcagagcggc tgcaaatgga
     1441 caatgagctc ctgaggcagc agatcgagga gctgaagaac gagaacgccc tgcttcgagc
     1501 ccaactgcag cagcacaacc tggaaatggt gggcgagagc acccggcagt gatgcccgct
     1561 ggctcaccct tcagctgctg ccggcctttg ctgcccctcc cccagccctt agcacagaga
     1621 gggagatgcc cctccccaag ctgcgttttt tatagtagat ttttaacaaa aacaaggaga
     1681 cataatgcat ttctgttgat acattgccca ctaccctccc ccatgcggaa atgatgtcca
     1741 cctgcccatc tgtccgtcag cctcccttct cggccctcac cagcccatca cttatagtgg
     1801 gctcatcggg aggagcgagg gaggaggaca gaggccccgc tgcccgctgc ctccttggtc
     1861 tctagaggta ttgagacagg gtgcttatgg gaaggaggga gctttgggga tgggggcctt
     1921 ccctggggcc tggacctatg cagggaggcc aagccccccc acccctcttg tttctggatc
     1981 cctgctcccc tctgggtgtg tgggtgtgta tgtgtgtgtg tgtgtgcgcg tgtgtatgtg
     2041 tgcgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtt ttaattttct ttatggaaaa
     2101 tggacaaaaa atagagagag aggtatttaa ctgcaataaa ctggccagtg tggccccgcc
     2161 taaaaaaaaa a
//
