LOCUS       XM_001066120            3376 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus urocanate hydratase 1 (Uroc1), mRNA.
ACCESSION   XM_001066120
VERSION     XM_001066120.7
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_001066120.8.
            
            On Jan 21, 2021 this sequence version replaced XM_001066120.6.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3376
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3376
                     /gene="Uroc1"
                     /note="urocanate hydratase 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 13
                     ESTs, 5 Proteins, and 96% coverage of the annotated
                     genomic feature by RNAseq alignments, including 4 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:685999"
                     /db_xref="RGD:1587777"
     CDS             34..2064
                     /gene="Uroc1"
                     /codon_start=1
                     /product="urocanate hydratase"
                     /protein_id="XP_001066120.2"
                     /db_xref="GeneID:685999"
                     /db_xref="RGD:1587777"
                     /translation="MSSLQELCSGLPLRPLPENRGRWAGVPHAPVRTPDLSPEEEQLA
                     LRNALRYFPPDVQKLLALEFAQELRQFGHIYMYRFCPSIEMRAYPIEQYPCRTRAAAA
                     IMHMIMNNLDPAVAQFPQELVTYGGNGQVFSNWAQFWLTMSYLSKMTEEQTLVMYSGH
                     PLGLFPSSSHAPRLVITNGMVIPNYSSRTEYEKLFALGVTMYGQMTAGSYCYIGPQGI
                     VHGTVLTVLNAGRRYLGIEDLAGKVFVTSGLGGMSGAQAKAAVIVGCIGVIAEVDKAA
                     LVKRHQQGWLMEVTDSLDHCIARLREARKKKEVLSLGYHGNVVDLWERLVHELDTTGE
                     LLVDLGSDQTSCHNPFNGGYYPVQLSFSEAQSLMSSNPAAFKNLVQESLRRHISAINR
                     LAQEKFFFWDYGNAFLLEAQRAGADVEKKGANKTEFRYPSYVQHIMGDIFSQGFGPFR
                     WVCTSGNPQDLTVTDHLATSVLEKAIADGVKASVKLQYMDNIRWIREAAKHQLVVGSQ
                     ARILYSDQKGRVAIAVAINQAIASGKIKAPVVLSRDHHDVSGTDSPFRETSNIYDGSA
                     FCADMAVQNFVGDACRGATWVALHNGGGVGWGEVINGGFGLVLDGTPEAEQKARMMLS
                     WDVSNGVARRCWSGNPKAYEIICQTMQENSGLVVTLPHEVADEQVLRQVLRL"
ORIGIN      
        1 ttcacactta ccttcacctc agtttcagcg gacatgtcca gcctccagga actgtgctct
       61 ggtctgcccc ttcgccccct ccctgagaac cggggtcgct gggctggagt gccacatgct
      121 ccggttagga ctcccgacct cagccctgag gaagagcagc tggcactgag gaatgcctta
      181 cgctacttcc cacctgatgt ccagaagctg ttggccctgg agtttgccca ggagctacga
      241 cagtttggac acatctacat gtacaggttc tgccccagca ttgaaatgag ggcttacccg
      301 attgagcagt acccatgccg gacacgggca gctgcagcca tcatgcacat gatcatgaac
      361 aacctggacc ctgctgtggc ccagtttcca caggagctgg tgacctacgg aggcaacggg
      421 caagtgttca gcaactgggc ccagttctgg ctgaccatgt cctacctgtc gaagatgacg
      481 gaggaacaga ctctggtcat gtacagtgga catcctctgg gcctcttccc cagcagctcc
      541 catgccccac ggctggtcat cactaatggg atggtcattc ccaactactc ctccaggaca
      601 gagtatgaga agctgtttgc cttgggggtg accatgtatg gacagatgac agcgggcagc
      661 tactgctaca ttggtcccca gggaattgtc catggcacag tgctcactgt gctgaatgcc
      721 ggtcggcggt acctgggcat cgaggatttg gcagggaagg tcttcgtcac ctctgggctt
      781 ggtgggatga gtggggctca agccaaggct gcggtcattg ttggatgtat tggggtgatt
      841 gcagaggttg acaaagctgc acttgtaaaa cgccaccagc aaggctggct gatggaggta
      901 accgacagct tggaccactg cattgcgaga ctcagggaag caagaaaaaa gaaggaggta
      961 ctcagcctcg gctaccatgg caacgtggtg gatctttggg agcgccttgt ccatgaactg
     1021 gacacaacag gggaactttt ggtggatctc gggtctgacc agacatcctg tcacaacccg
     1081 ttcaatggcg gctactaccc tgtgcagctc agcttctcag aagcccagag cctcatgtcc
     1141 tccaaccctg ctgccttcaa gaacctggta caggaaagcc tgaggagaca catctcagcc
     1201 atcaacaggt tggcccagga gaagttcttc ttttgggact atggtaatgc cttcctcttg
     1261 gaggctcaga gagcaggagc agatgtagag aagaaaggag ccaacaagac ggaattccgc
     1321 tacccctcct atgtccagca cattatgggg gatatattct cccagggctt tgggcccttc
     1381 cgctgggtat gcacatcagg aaacccccag gacctgactg tcactgatca tctggccaca
     1441 tctgtgctgg agaaagccat tgctgatgga gtgaaggcat ccgtgaagtt acagtatatg
     1501 gacaatatac gctggatccg ggaggctgcc aagcaccagc tggtggtggg ctcccaggca
     1561 aggatcctgt actcagacca gaaaggtcga gtggctattg cggtagctat aaaccaggcc
     1621 atcgccagtg ggaagatcaa ggcaccagtg gtcctgagcc gtgaccacca tgatgtgagt
     1681 ggcactgaca gcccctttag ggagacttcg aatatttatg acggttctgc cttctgcgca
     1741 gacatggccg tgcagaactt cgtaggagat gcctgtcgtg gtgccacctg ggttgcactt
     1801 cacaacggag ggggtgtagg ctggggtgag gtgatcaatg ggggatttgg ccttgttctc
     1861 gatgggaccc cagaggctga gcagaaagcc aggatgatgc tcagctggga tgtctccaat
     1921 ggcgtggcac ggcgttgctg gtctgggaac cccaaggcct atgagatcat ctgccagaca
     1981 atgcaggaaa acagtggcct ggtggtgact cttccccatg aggtggcaga tgaacaagtg
     2041 ctacgacagg tcctgcggct ctgaggagat cgtgggtcct cttgatcccc tccttcccac
     2101 tggcctcccc tcacagctca tcaccctccc cccccactac tacacccctc cctacatggc
     2161 actcttagtg tcccacatag taaaccacag aggcccatca agatggggct cttgcctttg
     2221 actactggct tcagggcagg gtacatagtg ttcacagaga agccataagc ctgcagtaga
     2281 gtagactcca gcttggatgg gaaggagtct tgatgctgac caagctggca ccagcctcac
     2341 agtagtctct gtgaccttct aaatgtgctg ttcagtctac tgtccactgc tgtccccaca
     2401 gtactaccca cccatccctt gtttatgcca tcacttctga ttcctcagag aacccggcac
     2461 gggtacacaa agtgctcaca ccaagtcctt ggtgctgagg gtatgggaaa gatataaagg
     2521 aagtaaagac caaaatagag gcaagcgcat ggcacagact gggctggcaa gagtgggtga
     2581 cagagtctct gaggcaaagt ggccaggtgc tactgcaacg tgtggagaaa agacactttc
     2641 caggccagct gtgtgagcat gaaacacaga accaaccact tccagaggtg cctgggtgga
     2701 tctggaatcc ttccggagtt gcattagcca taagctgggt tcttatacct tttccatgcc
     2761 ctgcaaccca atcagaccta ccccagcctt gcctctgaag caggagccct ggcaagagag
     2821 ttgggttgtg cttcctcaga cctccccctg gaagttacca ctgctttata agtgccccct
     2881 accccccaat acccagcttt tgggcccctc ccactactgt gtcctgtgcc ctcctttcaa
     2941 tctttaccag gccagctctc ctgctgtgtt gtcccctgag ctgaggcagg gctacttggc
     3001 agttaattta caaagagaaa agggatctat ctggctgaca gttctggatg tccccaccca
     3061 agatcaggaa gtcatattgc tttgggtctc tggcaacagt gccaaatggc agtggcaggg
     3121 cacacatggc agaacaaact gcttacactg tgaggcagga agaaagaaaa gacgcttgga
     3181 cccaagtgct acaatccctc aagggcatgt tccaataacc taaaggcctt tcccccagct
     3241 ctactgctaa aggattccat caccctttga ataagccttt agcccaatca ggagccatac
     3301 cagaggtcaa aactggcttt ctggcatttt ggtctatgtt ttcttgcata aaataaaatt
     3361 tttcctaaat caaaaa
//
