LOCUS       NM_001107507            3236 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus URI1, prefoldin-like chaperone (Uri1), mRNA.
ACCESSION   NM_001107507 XM_001077296 XM_218532
VERSION     NM_001107507.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3236)
  AUTHORS   Mita P, Savas JN, Djouder N, Yates JR 3rd, Ha S, Ruoff R, Schafler
            ED, Nwachukwu JC, Tanese N, Cowan NJ, Zavadil J, Garabedian MJ and
            Logan SK.
  TITLE     Regulation of androgen receptor-mediated transcription by RPB5
            binding protein URI/RMP
  JOURNAL   Mol Cell Biol 31 (17), 3639-3652 (2011)
   PUBMED   21730289
REFERENCE   2  (bases 1 to 3236)
  AUTHORS   Horejsi Z, Takai H, Adelman CA, Collis SJ, Flynn H, Maslen S,
            Skehel JM, de Lange T and Boulton SJ.
  TITLE     CK2 phospho-dependent binding of R2TP complex to TEL2 is essential
            for mTOR and SMG1 stability
  JOURNAL   Mol Cell 39 (6), 839-850 (2010)
   PUBMED   20864032
REFERENCE   3  (bases 1 to 3236)
  AUTHORS   Djouder N, Metzler SC, Schmidt A, Wirbelauer C, Gstaiger M,
            Aebersold R, Hess D and Krek W.
  TITLE     S6K1-mediated disassembly of mitochondrial URI/PP1gamma complexes
            activates a negative feedback program that counters S6K1 survival
            signaling
  JOURNAL   Mol Cell 28 (1), 28-40 (2007)
   PUBMED   17936702
REFERENCE   4  (bases 1 to 3236)
  AUTHORS   Delgermaa L, Hayashi N, Dorjsuren D, Nomura T, Thuy le TT and
            Murakami S.
  TITLE     Subcellular localization of RPB5-mediating protein and its putative
            functional partner
  JOURNAL   Mol Cell Biol 24 (19), 8556-8566 (2004)
   PUBMED   15367675
REFERENCE   5  (bases 1 to 3236)
  AUTHORS   Wei W, Gu JX, Zhu CQ, Sun FY, Dorjsuren D, Lin Y and Murakami S.
  TITLE     Interaction with general transcription factor IIF (TFIIF) is
            required for the suppression of activated transcription by
            RPB5-mediating protein (RMP)
  JOURNAL   Cell Res 13 (2), 111-120 (2003)
   PUBMED   12737519
REFERENCE   6  (bases 1 to 3236)
  AUTHORS   Dorjsuren D, Lin Y, Wei W, Yamashita T, Nomura T, Hayashi N and
            Murakami S.
  TITLE     RMP, a novel RNA polymerase II subunit 5-interacting protein,
            counteracts transactivation by hepatitis B virus X protein
  JOURNAL   Mol Cell Biol 18 (12), 7546-7555 (1998)
   PUBMED   9819440
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473979.2.
            
            [WARNING] On Mar 20, 2024 this sequence was replaced by
            NM_001107507.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001077296.1, XM_218532.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3236
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..3236
                     /gene="Uri1"
                     /gene_synonym="RGD1310358"
                     /note="URI1, prefoldin-like chaperone"
                     /db_xref="GeneID:308537"
                     /db_xref="RGD:1310358"
     exon            1..298
                     /gene="Uri1"
                     /gene_synonym="RGD1310358"
                     /inference="alignment:Splign:2.1.0"
     CDS             188..1780
                     /gene="Uri1"
                     /gene_synonym="RGD1310358"
                     /codon_start=1
                     /product="unconventional prefoldin RPB5 interactor 1"
                     /protein_id="NP_001100977.1"
                     /db_xref="GeneID:308537"
                     /db_xref="RGD:1310358"
                     /translation="MEPPSEPEPEPQPFAEASAAAPLRAPEVARLREEQEKVVTNCQE
                     KIQHWEKVDNDYSALQERLRTLPDKLSYDIMVPFGPLAFMPGKLVHTNEVTVLLGDNW
                     FAKCSAKQAVGLVEHRKEHVRKTIDDFKKVLKNFESRVEFTEDLQKMSDAAGDFVDIR
                     EEIKSDFEFKGKQRIAHKPHSKPKTSDIFEAEFENGIKPQGTFDDDELWARLEELERQ
                     EELLGELKSKPDTVIANGEDTVSSEEEKEDEDTGVNVVSPVTDSSAPSSCKRHGGNAG
                     LPNGQTSSLNYSVNGSNSYHSNKEDEEEEEEEDEDDDEEDDDDESDHAVSADNSIPTI
                     YFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKSGAASHSAHELPAIRSPADIYRV
                     FVDVVNGEYIPRKSILKSRSRENSVCSDTSESSAADVDIDRRAPLRSPSSEETEAGSS
                     TLEELQENHPKKPLPSGVSEAFSGTVIEKEFLSPSLAPHSAIAHHALPTIPERKEVLS
                     EASEEPAKRVSKFRAARLQQRN"
     exon            299..333
                     /gene="Uri1"
                     /gene_synonym="RGD1310358"
                     /inference="alignment:Splign:2.1.0"
     exon            334..412
                     /gene="Uri1"
                     /gene_synonym="RGD1310358"
                     /inference="alignment:Splign:2.1.0"
     exon            413..548
                     /gene="Uri1"
                     /gene_synonym="RGD1310358"
                     /inference="alignment:Splign:2.1.0"
     exon            549..640
                     /gene="Uri1"
                     /gene_synonym="RGD1310358"
                     /inference="alignment:Splign:2.1.0"
     exon            641..698
                     /gene="Uri1"
                     /gene_synonym="RGD1310358"
                     /inference="alignment:Splign:2.1.0"
     exon            699..867
                     /gene="Uri1"
                     /gene_synonym="RGD1310358"
                     /inference="alignment:Splign:2.1.0"
     exon            868..1219
                     /gene="Uri1"
                     /gene_synonym="RGD1310358"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1359
                     /gene="Uri1"
                     /gene_synonym="RGD1310358"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1597
                     /gene="Uri1"
                     /gene_synonym="RGD1310358"
                     /inference="alignment:Splign:2.1.0"
     exon            1598..3236
                     /gene="Uri1"
                     /gene_synonym="RGD1310358"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccgcggg tagcccggac gcgagcggcg gcccccgggg cagcggggaa agtgagcgcg
       61 gcctcttcag agagaggcgt gctgtgcatg agggcgagcg cgcgggctct gggcatccgt
      121 cggccacgcc gcctccataa acacttgttt aggacttgtt cgcctcgctg aggctgcgac
      181 gccgggcatg gagcccccgt ccgaaccgga gcccgagccc cagccctttg cagaggcctc
      241 agccgccgct ccgctgcgcg caccagaggt ggcgcggctt cgcgaggagc aggaaaaggt
      301 ggtcactaac tgccaagaga aaatccagca ttgggagaaa gtagacaatg actatagtgc
      361 tcttcaagag aggctgagga ccttgcctga caagttgtct tacgacatca tggtaccatt
      421 tggccctctt gccttcatgc caggaaaact tgtccatact aatgaagtca ctgttttact
      481 tggggacaac tggtttgcaa agtgctcagc gaagcaggcc gtgggtttag ttgagcatcg
      541 gaaagaacat gtaagaaaaa ccatagatga ttttaaaaaa gtgttgaaga attttgaatc
      601 cagagttgaa ttcacagaag atttgcagaa gatgagtgat gctgcaggtg attttgttga
      661 cataagagaa gaaattaaaa gcgactttga atttaaagga aaacaacgaa ttgctcataa
      721 acctcactcc aaaccaaaaa cttcagatat ttttgaagca gaatttgaaa atggtataaa
      781 accccagggt acgtttgatg atgatgaact gtgggctcgg cttgaagagc tggagagaca
      841 agaagagttg ctgggtgaac ttaaaagtaa gcctgatact gtaattgcaa atggagaaga
      901 cacagtgtct tctgaggaag aaaaagaaga tgaagacaca ggtgtgaatg tggtgtctcc
      961 agtgacagac tcctccgccc ccagcagctg taaaaggcat ggtggaaatg caggactccc
     1021 taatggtcag accagcagtc tgaactattc agtgaatggc tcaaattctt accatagcaa
     1081 caaagaagat gaagaagaag aagaagaaga agatgaagat gatgatgaag aagatgatga
     1141 tgatgaaagt gaccatgctg tttcagcaga taattctata ccaacaatat atttctctca
     1201 tactgttgaa ccaaaaaggg ttcgaataaa tactgggaaa aataccactt taaagttcag
     1261 tgagaagaaa gaggaagcca aacggaaacg aaagagtggt gctgcctctc actctgccca
     1321 tgagctacct gccatcagga gtcctgctga tatttacaga gtcttcgtgg atgtggtgaa
     1381 tggagaatac attcctcgga agtccatcct gaagtctcgt agccgagaga acagcgtgtg
     1441 cagcgacacg agcgagagca gtgctgcaga cgtggacatt gacagacggg cgcctctgcg
     1501 gagccccagc tctgaggaga ccgaggctgg cagcagcact ttggaggaac tccaagagaa
     1561 ccaccccaag aagcctttgc cctcaggagt gtctgaggct ttttctggaa ctgtaataga
     1621 aaaggaattt ttatcaccgt ccctagcacc acactcagcc attgctcatc atgccctacc
     1681 caccattcca gagcgaaaag aagttctgtc agaagcatca gaggaacccg caaagagggt
     1741 ttcgaagttc agagctgcga gattgcagca gagaaactag aggggatggg cttcacccgc
     1801 agctccagct gcgctttagg acatgcgcac ggcagaatcg gccatggagt tgggaaggcg
     1861 cccacttggc tggcagagtt ctctaccctt atcagtgttg gggaaggcag agtaaatgtt
     1921 tgaatgctgt aatgttctgc tggctttgtt aactctgtga ctactgtcta attggcctta
     1981 ggatgcagga agaacatttt aagttacttt tcaaagaaca ctgccgtgta ttgtttttgt
     2041 gtttccaact aaatgcaggc agtttcctac cagctgtgat gctgtgcttt ccatacggac
     2101 catgttcaag aaacttaaaa tttcaatagg ttccacagtt atattacttg cttttacatt
     2161 ttaaaggcac tttaaaaaaa atctacattt cttgtaggtt tcacagctag atagttcttt
     2221 gaaaaattct tcctttgaat gttgtactat aatctttaag gcaaaaagct acataaaccc
     2281 tttgggaaaa tttgaataga agaatatttt atacaaattt ttttgggaag taatattttt
     2341 atgaaacttg gtttctaaaa tgtggtaagc ttcctggttt agaattgtga ataagatgtc
     2401 tgatttgtgt ctatgctgta caggccatac cacagagttg tgaatcttta aagtcccata
     2461 agcacctcct ctccctacgt actgttttca ctggtttctt cctttgggaa agaaaagttt
     2521 gtctggatgc tttaaaattt cttaaagttt ttttgtttgt tttatgtttc agtctttctc
     2581 acattttgat tcttcaagat tgctttgcta ccagtaaaaa aaaaaatgaa atattatatt
     2641 tactctactc cttaaagagg cattcagttt cagattgact atacagtgca agtgttgatt
     2701 agcctggtgc atgctaaaat gtagctttta aaaagcatcc tgcattagta ctaaaataag
     2761 ccttcaaccc cagtccaccc tctattcatg gctaaatatt taaaggttat ttatagcttc
     2821 tttaatgaat tcttgcttaa acaaagtgga attatgtcct agaaaagtgg atgctgtaac
     2881 tagagcagtg ccactgtcaa agttctatga aatacatact ttaatgataa aatggtgggc
     2941 ttggacctgg gcactgattt gaaagactgc ctaaagctgt aatagctctg tttttctagc
     3001 tgttgttgat catctgtcca tgtattttgt acttaaaacc cacttttctt tccggtgacc
     3061 tactctcgac cagactatcc catctcgtgg actccaggtg cgccctgttc cttctcctta
     3121 cacgaggctt cctgtgctaa cccctcctga tgcaagcctc cttgtaggac tgttggatct
     3181 tcagacatgt aacttaagtg tgttgttatt aaacaacttt ctgtgttcat gaactt
//
