LOCUS       NM_001009480             576 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ubiquinol-cytochrome c reductase hinge protein
            (Uqcrh), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001009480 XM_345568
VERSION     NM_001009480.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 576)
  AUTHORS   Guo,R., Zong,S., Wu,M., Gu,J. and Yang,M.
  TITLE     Architecture of Human Mitochondrial Respiratory Megacomplex
            I2III2IV2
  JOURNAL   Cell 170 (6), 1247-1257 (2017)
   PUBMED   28844695
REFERENCE   2  (bases 1 to 576)
  AUTHORS   Zhao,X., Leon,I.R., Bak,S., Mogensen,M., Wrzesinski,K., Hojlund,K.
            and Jensen,O.N.
  TITLE     Phosphoproteome analysis of functional mitochondria isolated from
            resting human muscle reveals extensive phosphorylation of inner
            membrane protein complexes and enzymes
  JOURNAL   Mol Cell Proteomics 10 (1), M110.000299 (2011)
   PUBMED   20833797
REFERENCE   3  (bases 1 to 576)
  AUTHORS   Schilling,B., Murray,J., Yoo,C.B., Row,R.H., Cusack,M.P.,
            Capaldi,R.A. and Gibson,B.W.
  TITLE     Proteomic analysis of succinate dehydrogenase and
            ubiquinol-cytochrome c reductase (Complex II and III) isolated by
            immunoprecipitation from bovine and mouse heart mitochondria
  JOURNAL   Biochim Biophys Acta 1762 (2), 213-222 (2006)
   PUBMED   16120479
REFERENCE   4  (bases 1 to 576)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 576)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   6  (bases 1 to 576)
  AUTHORS   Sun,G., Kinter,M.T. and Anderson,V.E.
  TITLE     Mass spectrometric characterization of mitochondrial electron
            transport complexes: subunits of the rat heart ubiquinol-cytochrome
            c reductase
  JOURNAL   J Mass Spectrom 38 (5), 531-539 (2003)
   PUBMED   12794875
REFERENCE   7  (bases 1 to 576)
  AUTHORS   Kim,C.H., Balny,C. and King,T.E.
  TITLE     Role of the hinge protein in the electron transfer between cardiac
            cytochrome c1 and c. Equilibrium constants and kinetic probes
  JOURNAL   J Biol Chem 262 (17), 8103-8108 (1987)
   PUBMED   3036796
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086954.1.
            
            On Jan 7, 2005 this sequence version replaced XM_345568.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086954.1, CO561861.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..576
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q35"
     gene            1..576
                     /gene="Uqcrh"
                     /note="ubiquinol-cytochrome c reductase hinge protein"
                     /db_xref="GeneID:366448"
                     /db_xref="RGD:1305987"
     exon            1..85
                     /gene="Uqcrh"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..301
                     /gene="Uqcrh"
                     /EC_number="7.1.1.8"
                     /note="complex III subunit 6; complex III subunit VIII;
                     mitochondrial hinge protein; cytochrome c1 non-heme 11 kDa
                     protein; ubiquinol-cytochrome c reductase complex 11 kDa
                     protein"
                     /codon_start=1
                     /product="cytochrome b-c1 complex subunit 6,
                     mitochondrial"
                     /protein_id="NP_001009480.1"
                     /db_xref="GeneID:366448"
                     /db_xref="RGD:1305987"
                     /translation="MGLEDERKMLTGSGDPKEEEEEELVDPLTTVREHCEQLEKCVKA
                     RERLESCDRRVSSRSQTEEDCTEELFDFLHARDHCVAHKLFKSLK"
     exon            86..106
                     /gene="Uqcrh"
                     /inference="alignment:Splign:2.1.0"
     exon            107..268
                     /gene="Uqcrh"
                     /inference="alignment:Splign:2.1.0"
     exon            269..551
                     /gene="Uqcrh"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcttggtgtt gaatcccaaa ccggctccgc catgggacta gaggatgaac gaaagatgct
       61 cactggctcc ggagacccca aagaggaaga agaggaagaa ttagtggacc ccctgacaac
      121 agtgagagag cactgtgagc agttggagaa gtgtgtaaaa gcccgggaac gactagagtc
      181 gtgtgatagg cgcgtgtctt cccgatcaca gacagaagag gattgtacag aggagctctt
      241 tgacttcctg catgcacggg atcactgtgt ggcccacaaa ctcttcaaaa gcttgaagta
      301 aacatgcaga gtcgcttgcc tcagcctcgt cactgggaat cggaacagct tgctgtgctt
      361 ttgaacattt gtttctaacg taggaagttc ttgagaacct ccttgatttt ggcaagtagc
      421 ttctcttctg tgaagttagc agagattcca cctcaataaa ctcatccgca aacttgctac
      481 ttgtccttcc tttgctgtag ccctacttta ttattatatt ttaaatatta aaaatttttt
      541 tctccataaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//
