LOCUS       NM_001399168             397 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus ubiquinol-cytochrome c reductase complex assembly
            factor 5 (Uqcc5), mRNA.
ACCESSION   NM_001399168 XM_341397
VERSION     NM_001399168.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Zhang,D., Pan,N., Jiang,C. and Hao,M.
  TITLE     LncRNA SNHG8 sponges miR-449c-5p and regulates the SIRT1/FoxO1
            pathway to affect microglia activation and blood-brain barrier
            permeability in ischemic stroke
  JOURNAL   J Leukoc Biol 111 (5), 953-966 (2022)
   PUBMED   34585441
  REMARK    GeneRIF: LncRNA SNHG8 sponges miR-449c-5p and regulates the
            SIRT1/FoxO1 pathway to affect microglia activation and blood-brain
            barrier permeability in ischemic stroke.
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   3  (bases 1 to 397)
  AUTHORS   Liu,Y., Zhou,P., Wang,F., Zhang,X., Yang,D., Hong,L. and Ruan,D.
  TITLE     Inhibition of lncRNA SNHG8 plays a protective role in
            hypoxia-ischemia-reoxygenation-induced myocardial injury by
            regulating miR-335 and RASA1 expression
  JOURNAL   Mol Med Rep 24 (2) (2021)
   PUBMED   34165173
  REMARK    GeneRIF: Inhibition of lncRNA SNHG8 plays a protective role in
            hypoxia-ischemia-reoxygenation-induced myocardial injury by
            regulating miR-335 and RASA1 expression.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On Jan 4, 2022 this sequence version replaced XM_341397.8.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK840141.1, AA996717.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840109, SAMN12840117
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-293               JAXUCZ010000016.1  6326619-6326911     c
            294-397             JAXUCZ010000016.1  6323071-6323174     c
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p16"
     gene            1..397
                     /gene="Uqcc5"
                     /gene_synonym="Smim4; Snhg8"
                     /note="ubiquinol-cytochrome c reductase complex assembly
                     factor 5"
                     /db_xref="GeneID:361111"
                     /db_xref="RGD:1307583"
     exon            1..293
                     /gene="Uqcc5"
                     /gene_synonym="Smim4; Snhg8"
                     /inference="alignment:Splign:2.1.0"
     CDS             146..385
                     /gene="Uqcc5"
                     /gene_synonym="Smim4; Snhg8"
                     /note="small nucleolar RNA host gene (non-protein coding)
                     8"
                     /codon_start=1
                     /product="small integral membrane protein 4"
                     /protein_id="NP_001386097.1"
                     /db_xref="GeneID:361111"
                     /db_xref="RGD:1307583"
                     /translation="MFRAQLRRALQRVPGKQRFGIYRFLPFFFVLGGTMEWIMIKVRV
                     GQETFYDVYRRKASERQYQRRLEDISETNLHKLIK"
     exon            294..397
                     /gene="Uqcc5"
                     /gene_synonym="Smim4; Snhg8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cactcttgcg gccggactgt ggcgctgcaa tccagtcttg ctactcggtc cacgggactt
       61 cgcgggacgc gcagggacgt ttgtactgcc tctaggaaca ccagtctacc tggttccgcc
      121 cgtaccccac tttgaggcct cggtcatgtt cagggcccag ctgaggcgag ctcttcagcg
      181 agtgcctggg aagcagcgat tcggcatcta cagattcctg cccttctttt ttgtcctggg
      241 aggaacgatg gagtggatca tgattaaagt gcgcgtgggc caggagacct tctatgatgt
      301 ctaccgtaga aaagcttcag aaagacagta tcagagaagg ctggaagata tatcagaaac
      361 caatcttcat aagctaataa agtgaacttt cagtgtt
//
