LOCUS       NM_001398810            2362 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus uroplakin 3B (Upk3b), mRNA.
ACCESSION   NM_001398810 XM_341056
VERSION     NM_001398810.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2362)
  AUTHORS   Reis,L.O., Ferrari,K., Zamuner,M., Rocha,G.Z., Billis,A. and
            Favaro,W.J.
  TITLE     Urothelial carcinogen resistance driven by stronger Toll-like
            receptor 2 (TLR2) and Uroplakin III (UP III) defense mechanisms: a
            new model
  JOURNAL   World J Urol 33 (3), 413-419 (2015)
   PUBMED   24871424
  REMARK    GeneRIF: Preservation of TLR2 and UP III defense mechanisms might
            drive diverse urothelial phenotypes during carcinogenesis in
            differently susceptible individuals.
REFERENCE   2  (bases 1 to 2362)
  AUTHORS   Drerup,J.M., Hayashi,K., Cui,H., Mettlach,G.L., Long,M.A.,
            Marvin,M., Sun,X., Goldberg,M.S., Lutter,M. and Bibb,J.A.
  TITLE     Attention-deficit/hyperactivity phenotype in mice lacking the
            cyclin-dependent kinase 5 cofactor p35
  JOURNAL   Biol Psychiatry 68 (12), 1163-1171 (2010)
   PUBMED   20832057
REFERENCE   3  (bases 1 to 2362)
  AUTHORS   Foot,N.J., Dalton,H.E., Shearwin-Whyatt,L.M., Dorstyn,L., Tan,S.S.,
            Yang,B. and Kumar,S.
  TITLE     Regulation of the divalent metal ion transporter DMT1 and iron
            homeostasis by a ubiquitin-dependent mechanism involving Ndfips and
            WWP2
  JOURNAL   Blood 112 (10), 4268-4275 (2008)
   PUBMED   18776082
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Dec 23, 2021 this sequence version replaced XM_341056.9.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KU310912.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760400,
                                           SAMEA5760434 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-173               JAXUCZ010000012.1  26274068-26274240   c
            174-323             JAXUCZ010000012.1  26273763-26273912   c
            324-549             JAXUCZ010000012.1  26272568-26272793   c
            550-629             JAXUCZ010000012.1  26270974-26271053   c
            630-759             JAXUCZ010000012.1  26269363-26269492   c
            760-2362            JAXUCZ010000012.1  26266838-26268440   c
FEATURES             Location/Qualifiers
     source          1..2362
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q12"
     gene            1..2362
                     /gene="Upk3b"
                     /gene_synonym="RGD1309615"
                     /note="uroplakin 3B"
                     /db_xref="GeneID:360790"
                     /db_xref="RGD:1309615"
     exon            1..173
                     /gene="Upk3b"
                     /gene_synonym="RGD1309615"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..919
                     /gene="Upk3b"
                     /gene_synonym="RGD1309615"
                     /note="uroplakin-3b"
                     /codon_start=1
                     /product="uroplakin-3b precursor"
                     /protein_id="NP_001385739.1"
                     /db_xref="GeneID:360790"
                     /db_xref="RGD:1309615"
                     /translation="MEFTRMRPHPWPLLLPVLMWLPQSLSLDLIPYTPQITARDLGGK
                     VTATTFSLEQPRCVFDEHASSNDTIWLVVAFSNASRDFQNPQTAAKIPTFPQLLTDGH
                     YMTLPLSLDQLPCEDLTGGSGGVQVLRVGNDFGCYQRPYCNAPLPSQGPYSVKFLVMD
                     AGGPPKAETKWSNPIFLHQGKNPNAIDTWPGRRSGCMIVITSILPVLAGLLLLAFLAA
                     STTRFSSLWWPEEAPEQLRIGSFMGKRYMTHHIPPSEAATLPVGCEPGLDPLPSLSP"
     exon            174..323
                     /gene="Upk3b"
                     /gene_synonym="RGD1309615"
                     /inference="alignment:Splign:2.1.0"
     exon            324..549
                     /gene="Upk3b"
                     /gene_synonym="RGD1309615"
                     /inference="alignment:Splign:2.1.0"
     exon            550..629
                     /gene="Upk3b"
                     /gene_synonym="RGD1309615"
                     /inference="alignment:Splign:2.1.0"
     exon            630..759
                     /gene="Upk3b"
                     /gene_synonym="RGD1309615"
                     /inference="alignment:Splign:2.1.0"
     exon            760..2362
                     /gene="Upk3b"
                     /gene_synonym="RGD1309615"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagtccaag tgaccatcaa ctgtaggcca gaggtgttgg aggtggggtg agacagacca
       61 gcccctaagc ctggtcagtg ctgtggcaga catggagttc acccggatgc ggcctcaccc
      121 ttggcccctg cttctcccgg tacttatgtg gcttccccaa agcctgagtc tagacctgat
      181 tccctacacg ccgcagataa ctgccaggga cctgggaggg aaggtcacag ccactacgtt
      241 ctctctggag cagcctcggt gcgtctttga tgagcacgcc tcaagtaatg acaccatctg
      301 gctagtggtg gctttcagca atgcctccag ggactttcag aacccacaga ccgctgctaa
      361 gatcccgacc ttcccacagc tgctgactga cggccactat atgacattac ccctgtccct
      421 ggatcagctg ccatgtgagg acctgaccgg tggcagtgga ggtgttcagg tgcttcgggt
      481 gggcaatgac ttcggctgtt accagcgacc ctattgcaac gctcccctcc ccagccaggg
      541 cccttacagt gtgaagttcc ttgtaatgga tgctggtggc ccacccaagg ctgaaacgaa
      601 gtggtctaat cccatttttc tccaccaagg gaagaacccc aacgccattg acacatggcc
      661 tggtcggcgg agcggctgta tgatcgtcat aacttctatc cttccggtcc tggccggcct
      721 cttgctcctg gctttcctgg cagcctccac tacgcgtttc tccagcctgt ggtggcctga
      781 ggaagcccct gagcagctgc ggattggctc cttcatggga aaacgttaca tgactcacca
      841 tatccccccc agcgaggctg ccacactgcc ggtgggctgc gagcctggcc tggaccccct
      901 tcccagtctc agcccatagc ttggtctctg gatcttgggc tggtgtgagg ggcacagagc
      961 aggtgcccct cctgtggggc agggtggggc ccttgcatct ccacagcccc tcctatctgc
     1021 ctggctgttt tatcttctgc gtctggttct gtctgtcact cgcctctgta tgtaagtgca
     1081 tttacaagat caggatcagt ttgatccttt tttttttttt ttgttctttt tttcggagct
     1141 ggggaccgaa cccagggcct tgcgcttcct aggcaagcgc tctaccactg agctaaatcc
     1201 ccaaccccca gtttgatcct tgataacccc cttcacgtaa ggctcaagga tgtggttcac
     1261 cctcacctta gccagacttc agagaaccca ggaggagatg ggtaacacga ggccgtgatc
     1321 cccaccctta ggaggctgag gtaggagggt catgtgctcc aggctagtct gggctatgga
     1381 gcaagagcag gtctcgaaca aaacaaaaca aaacaaaaca aaacaaaaca aaacaaaaca
     1441 aaacagaaac acacaaccct gggaggcagc cttgttgggc agttagtagg ttgggctggg
     1501 ccatcacgag ggtatgaggc tccatcctac ccaacaacca gggatggggt gctgctgcag
     1561 aaataccact atgcaggggt tggggattta gctcagtggt agagcgcttg cctagcaatc
     1621 gcaaggccct gggttcggtc ctcagctccg gaaaaaaaaa acccactatg gtctcctcac
     1681 tttctgaggc tgggtctcac cagtgtgctg gttagagagt gtgaatggtt actaatgaca
     1741 gctcggctac ctaccccagt ccctgtgcac agagagatgc ttcgagcact tctctgctga
     1801 ctcagcatca tttattgcgc acctgccctt ctgtaccaca tacagtgtca gacgacacgg
     1861 cctggggtcg caaagctgct cgtgactttg gaggactctc caccttgctt tgaatctcag
     1921 actgacacct gtccagatgt gggatctatt actgttgggg agatgccatg tcctcaaact
     1981 gtcctcaggg tcacactctc ccaattacca cagcgggctc ctcgcgactt tttcaaagga
     2041 aaagatctcc aggacaaagc cagtgcttcc tgccatcacc acacgggggc gtccgcaaga
     2101 tgtagctacg tggcagcagg gccctgagca gttcactcca gtttactgct ccatctgcac
     2161 tcctgtcttt tcaggggtca gggaagaatg tgttccagct catccagggc gagcccgcgg
     2221 ggctaccatg ttctctttaa tggcgaccct tgtgactaat cattgacttt cctgaccaca
     2281 ctgtttagcc accctacccc atgtcccatg gggcttgttt gatcaagctc ttaggaagtt
     2341 aataaatgtt attatggcag ga
//
